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The map label for this gene is xcpR [H]

Identifier: 77458209

GI number: 77458209

Start: 2263533

End: 2265254

Strand: Direct

Name: xcpR [H]

Synonym: Pfl01_1982

Alternate gene names: 77458209

Gene position: 2263533-2265254 (Clockwise)

Preceding gene: 77458208

Following gene: 77458210

Centisome position: 35.16

GC content: 62.83

Gene sequence:

>1722_bases
ATGGATCGTCTGTCCGTTGTCGTCGAACCGCTGTCGGTCAATCCTCCACAGGAGGCACAGACCCCGCCACGCTTTTCCAG
TGAGCAACTGGCCCAGGCCCGGGCACGGGCCACCACGTCCGGGGAACGGGTGCTCGATGCACTGGCCGTGCTCTGCGAAC
TGGCGCCGATGCCGTTCATTGCCAGCCTCGGCGCCACCCTGCATTACCCGGTGCTCGACACCGACACGCTGTTTCTGGCG
ACCCCGGTGTTCGACCGGGTCACCCTCGCGCAATGCCTCAAACGTGAATTCATCCTGCTGCGCCACAACGACGAAGTCAT
CGGCGTGTTCGCCGACCCCTTCGACACGTCGCGCCTGGCCTGGATCGACGAATGCCTGCATGGCGCACCGCTGTATCTGG
TGCATGCCGACGACCTCAAGGCTTATCTGGCCCGCCACGAAGAAAGTTTCCACGCCGTCGAATCGCTCAACGCCCAGGCC
GACGCCGGCAGCGAAACCGACACTCTGCAAAGCCTGTCGTTGACCAGCATCAGCGAAGATTCGAGCGTGGTGGTGAAACT
GGTCAACTCGACCCTGTACGACGCGCTGAAAATGCACGCCAGCGATATCCACCTCGGCACCACCGGCCAGGGCCTGGTGA
TCAAGTACCGGATCGACGGCGTGCTGAACAACATAGGCAAGATCCAGGGCAGCGAGTTCGCCGAGCAGGTGATCTCGCGG
GTCAAGGTCATGGCCGAACTGGACATCGGCGAAAAACGCGTGCCCCAGGACGGTCGCTTCAAGATCGGCATCAGCGGCCG
GCAGATCGACTTCCGGGTGTCGATCATGCCGAGCATCTTCGGCGAAGACGCGGTGCTGCGGGTGCTGGACAAACAGGACC
TGGCCGACAAGGTCTGCGGCGTGCAACTGCAAGCGCTGGGCTTTGAAGACGAAACCCTGCGCCAACTGCGTCGCCTGGCT
GCCGAACCCTACGGCATGGTACTGGTGACCGGCCCCACCGGCAGCGGCAAGACCACCACGCTGTACGCGATGATCACCGA
GATCAACCACGGCGTGGACAAGATCATCACCATCGAAGACCCGGTGGAATATCAGCTGCCGGGCGTGCTGCAAATCCCGG
TCAACGAGAAAAAAGGCCTGACCTTCGCCCGTGGCCTGCGCTCGATCCTGCGCCACGACCCGGACAAGATCATGGTCGGC
GAGATCCGCGACCCGGACACCGCACAGATCGCCGTGCAATCGGCGCTCACCGGTCACCTGGTGTTCACCACCATTCACGC
CAACAACGTGTTCGACGTGATCGGTCGTTTTACCCAAATGGAAATCGACCCCTACAGCCTGGTCTCGGCGCTCAACGCGA
TTCTTGCCCAGCGCCTGATCCGGCTGGTGTGCAGCAGCTGCAGCACGCCGGTCAATCCGAGCGATGAAGAGCTGCGCGCC
TCGGGCCTCGATCCACAGAAAGTCGATCACTACCACTTCGTCCACGGCAAGGGCTGCGGCCACTGCCGGGGCAGCGGCTA
TCGCGGCCGCACGGCGATTGCCGAGCTGCTGCACCTGGACGACGAACTGCGTCAGATGATCGTCGAGCGCCAACCCATCA
CCCAGATCAAAGCCCTGGCCTGCGCCCGTGGTTTGCGCCTGTTGCGCGAATCGGCGCTGGAACTGGTGGAGCACGGTCGG
ACCACGCTGGAGGAGATCAATCGTGTCACTTTTATCGCGTGA

Upstream 100 bases:

>100_bases
TGCTCACCGGGGAGTAATGGCGCGATAGACGTTCCGGCACTCGCCGAATTCGCCTCCCGCGCCGTCAGGGCCTCAAGCCC
CGGGTGTTGGAGAGCAAGCC

Downstream 100 bases:

>100_bases
TCAATTTATCGCCGTGCTCGGCGCCAGCGGTGTCGGCCTCGGCCAGCGCCGGGGCAGCGACACCCTGTGGCTGGGCAGCG
TCGGCTACATCGACGAAGGC

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MDRLSVVVEPLSVNPPQEAQTPPRFSSEQLAQARARATTSGERVLDALAVLCELAPMPFIASLGATLHYPVLDTDTLFLA
TPVFDRVTLAQCLKREFILLRHNDEVIGVFADPFDTSRLAWIDECLHGAPLYLVHADDLKAYLARHEESFHAVESLNAQA
DAGSETDTLQSLSLTSISEDSSVVVKLVNSTLYDALKMHASDIHLGTTGQGLVIKYRIDGVLNNIGKIQGSEFAEQVISR
VKVMAELDIGEKRVPQDGRFKIGISGRQIDFRVSIMPSIFGEDAVLRVLDKQDLADKVCGVQLQALGFEDETLRQLRRLA
AEPYGMVLVTGPTGSGKTTTLYAMITEINHGVDKIITIEDPVEYQLPGVLQIPVNEKKGLTFARGLRSILRHDPDKIMVG
EIRDPDTAQIAVQSALTGHLVFTTIHANNVFDVIGRFTQMEIDPYSLVSALNAILAQRLIRLVCSSCSTPVNPSDEELRA
SGLDPQKVDHYHFVHGKGCGHCRGSGYRGRTAIAELLHLDDELRQMIVERQPITQIKALACARGLRLLRESALELVEHGR
TTLEEINRVTFIA

Sequences:

>Translated_573_residues
MDRLSVVVEPLSVNPPQEAQTPPRFSSEQLAQARARATTSGERVLDALAVLCELAPMPFIASLGATLHYPVLDTDTLFLA
TPVFDRVTLAQCLKREFILLRHNDEVIGVFADPFDTSRLAWIDECLHGAPLYLVHADDLKAYLARHEESFHAVESLNAQA
DAGSETDTLQSLSLTSISEDSSVVVKLVNSTLYDALKMHASDIHLGTTGQGLVIKYRIDGVLNNIGKIQGSEFAEQVISR
VKVMAELDIGEKRVPQDGRFKIGISGRQIDFRVSIMPSIFGEDAVLRVLDKQDLADKVCGVQLQALGFEDETLRQLRRLA
AEPYGMVLVTGPTGSGKTTTLYAMITEINHGVDKIITIEDPVEYQLPGVLQIPVNEKKGLTFARGLRSILRHDPDKIMVG
EIRDPDTAQIAVQSALTGHLVFTTIHANNVFDVIGRFTQMEIDPYSLVSALNAILAQRLIRLVCSSCSTPVNPSDEELRA
SGLDPQKVDHYHFVHGKGCGHCRGSGYRGRTAIAELLHLDDELRQMIVERQPITQIKALACARGLRLLRESALELVEHGR
TTLEEINRVTFIA
>Mature_573_residues
MDRLSVVVEPLSVNPPQEAQTPPRFSSEQLAQARARATTSGERVLDALAVLCELAPMPFIASLGATLHYPVLDTDTLFLA
TPVFDRVTLAQCLKREFILLRHNDEVIGVFADPFDTSRLAWIDECLHGAPLYLVHADDLKAYLARHEESFHAVESLNAQA
DAGSETDTLQSLSLTSISEDSSVVVKLVNSTLYDALKMHASDIHLGTTGQGLVIKYRIDGVLNNIGKIQGSEFAEQVISR
VKVMAELDIGEKRVPQDGRFKIGISGRQIDFRVSIMPSIFGEDAVLRVLDKQDLADKVCGVQLQALGFEDETLRQLRRLA
AEPYGMVLVTGPTGSGKTTTLYAMITEINHGVDKIITIEDPVEYQLPGVLQIPVNEKKGLTFARGLRSILRHDPDKIMVG
EIRDPDTAQIAVQSALTGHLVFTTIHANNVFDVIGRFTQMEIDPYSLVSALNAILAQRLIRLVCSSCSTPVNPSDEELRA
SGLDPQKVDHYHFVHGKGCGHCRGSGYRGRTAIAELLHLDDELRQMIVERQPITQIKALACARGLRLLRESALELVEHGR
TTLEEINRVTFIA

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=448, Percent_Identity=41.9642857142857, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1786296, Length=415, Percent_Identity=37.1084337349398, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI87082188, Length=145, Percent_Identity=44.8275862068966, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 63089; Mature: 63089

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLSVVVEPLSVNPPQEAQTPPRFSSEQLAQARARATTSGERVLDALAVLCELAPMPFI
CCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHH
ASLGATLHYPVLDTDTLFLATPVFDRVTLAQCLKREFILLRHNDEVIGVFADPFDTSRLA
HHCCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHCEEEEEECCCEEEEEECCCCCCHHH
WIDECLHGAPLYLVHADDLKAYLARHEESFHAVESLNAQADAGSETDTLQSLSLTSISED
HHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCEECCCCCC
SSVVVKLVNSTLYDALKMHASDIHLGTTGQGLVIKYRIDGVLNNIGKIQGSEFAEQVISR
HHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEEECHHHHHHHCCCCHHHHHHHHHH
VKVMAELDIGEKRVPQDGRFKIGISGRQIDFRVSIMPSIFGEDAVLRVLDKQDLADKVCG
HHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHHC
VQLQALGFEDETLRQLRRLAAEPYGMVLVTGPTGSGKTTTLYAMITEINHGVDKIITIED
CEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEHHHCCCCCEEEEECC
PVEYQLPGVLQIPVNEKKGLTFARGLRSILRHDPDKIMVGEIRDPDTAQIAVQSALTGHL
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEE
VFTTIHANNVFDVIGRFTQMEIDPYSLVSALNAILAQRLIRLVCSSCSTPVNPSDEELRA
EEEEEECCCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SGLDPQKVDHYHFVHGKGCGHCRGSGYRGRTAIAELLHLDDELRQMIVERQPITQIKALA
CCCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
CARGLRLLRESALELVEHGRTTLEEINRVTFIA
HHHHHHHHHHHHHHHHHCCCHHHHHCCHHEECC
>Mature Secondary Structure
MDRLSVVVEPLSVNPPQEAQTPPRFSSEQLAQARARATTSGERVLDALAVLCELAPMPFI
CCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHH
ASLGATLHYPVLDTDTLFLATPVFDRVTLAQCLKREFILLRHNDEVIGVFADPFDTSRLA
HHCCCEEECCCCCCCCEEEECCHHHHHHHHHHHHHCEEEEEECCCEEEEEECCCCCCHHH
WIDECLHGAPLYLVHADDLKAYLARHEESFHAVESLNAQADAGSETDTLQSLSLTSISED
HHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCEECCCCCC
SSVVVKLVNSTLYDALKMHASDIHLGTTGQGLVIKYRIDGVLNNIGKIQGSEFAEQVISR
HHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEEEECHHHHHHHCCCCHHHHHHHHHH
VKVMAELDIGEKRVPQDGRFKIGISGRQIDFRVSIMPSIFGEDAVLRVLDKQDLADKVCG
HHHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHHC
VQLQALGFEDETLRQLRRLAAEPYGMVLVTGPTGSGKTTTLYAMITEINHGVDKIITIED
CEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEHHHCCCCCEEEEECC
PVEYQLPGVLQIPVNEKKGLTFARGLRSILRHDPDKIMVGEIRDPDTAQIAVQSALTGHL
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCCEE
VFTTIHANNVFDVIGRFTQMEIDPYSLVSALNAILAQRLIRLVCSSCSTPVNPSDEELRA
EEEEEECCCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SGLDPQKVDHYHFVHGKGCGHCRGSGYRGRTAIAELLHLDDELRQMIVERQPITQIKALA
CCCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
CARGLRLLRESALELVEHGRTTLEEINRVTFIA
HHHHHHHHHHHHHHHHHCCCHHHHHCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]