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The map label for this gene is rtcB [H]

Identifier: 77458173

GI number: 77458173

Start: 2221079

End: 2222308

Strand: Direct

Name: rtcB [H]

Synonym: Pfl01_1946

Alternate gene names: 77458173

Gene position: 2221079-2222308 (Clockwise)

Preceding gene: 77458172

Following gene: 77458174

Centisome position: 34.5

GC content: 60.24

Gene sequence:

>1230_bases
ATGATGAAAGAACACACTTACCAACTGCTGGAAGTCGCCAACGGCAAACCGATCAAGCTCTGGACCGAAGGCGTCCCGGT
GGAAAACGAAGCGCGCGAGCAGTTGATGAACACGGCGAAGATGCCCTTCATCTTCAAGCATCTGGCAGTGATGCCGGACG
TCCATCTGGGCAAGGGCTCGACCATCGGCAGCGTGATTCCCACGGTCGGCGCGATCATCCCGGCAGCGGTCGGGGTGGAC
ATCGGTTGCGGCATGATTGCCGCGCGAACCTCGCTGACGGCGGCCGATCTGCCGGACAATCTGCATGGCCTGCGCAGTGC
CATCGAGCAAGCGGTGCCCCATGGCCGCAGTTCGACCCGCTCGCGCCGTGACAAAGGCGCCTGGGACGAGATTCCGCAAC
AGGCCGATCAGGCCTGGGCGGCGCTGAATCCACGCTTTAAGGCGATCACCGACAAGTACCCGAAACTGGCCAACACCAAC
AACCGCGGGCATCTCGGAACACTGGGCAGCGGTAACCACTTCATCGAAGTGTGCCTGGATGAGGCCAACCGGGTCTGGTT
CATGTTGCACAGTGGCTCGCGCGGTGTCGGCAACGCCATCGGCAACCTGTTCATCCAGATGGCCCAGGCGGATATGCGTC
AGCACATCGCCAACCTGCCGGATCGTGATCTGGCGTACTTCGAAGAAGGCAGCCGGCATTTTGATGACTACGTGGAGGCG
GTGGGCTGGGCTCAGGATTTCGCCAAACAGAACCGTGCGCTGATGATGCAAGCGGTGATTCAGGCCACGCGACAGATTAT
CCGCAAGCCATTCGAAGTCGCGCTGGAAGCGGTGAACTGCCACCACAACTACGTGCAGAAAGAGCGGCATTTCGGCGAGG
ACATTCTGGTCACCCGCAAAGGCGCGGTGTCAGCGAAGAAGGGCGAGTTGGGGATCATTCCCGGTTCGATGGGCGCCAAG
AGTTTCATCGTGCGCGGTCTGGGCAACGAAGAATCGTTTTGCTCCTGCAGCCACGGTGCCGGTCGGACCATGAGCCGTAC
CAAGGCCAAAAACACCTTCACCGTCGAAGACCAGATCCGCGCCACCGCGCACGTCGAATGTCGCAAGGACGCTGCGGTGA
TCGATGAAATTCCGATGGCCTACAAGGATATCGACAAAGTCATGCACGCCCAGCGTGAGCTGGTTGAGGTGCTGCACACC
CTGCGTCAGGTGGTGTGCGTCAAGGGATAA

Upstream 100 bases:

>100_bases
CAACCCCGGTGCGCGGCAACGCGCAACAGTCATCAATCTTTGTCGTGCCACCTTTTTGAATCCGCCGGCGAATGCCGGTG
GAACTACCTGAAGAATCGAG

Downstream 100 bases:

>100_bases
CGCGTGCCGCCAGGCACGCCGGAACAAGGATTAAAGGACATGAAATTCGAAGAACGTCACCCGCTGTGCAACACCATGCG
CGCCCGGGTACTGGAAGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MMKEHTYQLLEVANGKPIKLWTEGVPVENEAREQLMNTAKMPFIFKHLAVMPDVHLGKGSTIGSVIPTVGAIIPAAVGVD
IGCGMIAARTSLTAADLPDNLHGLRSAIEQAVPHGRSSTRSRRDKGAWDEIPQQADQAWAALNPRFKAITDKYPKLANTN
NRGHLGTLGSGNHFIEVCLDEANRVWFMLHSGSRGVGNAIGNLFIQMAQADMRQHIANLPDRDLAYFEEGSRHFDDYVEA
VGWAQDFAKQNRALMMQAVIQATRQIIRKPFEVALEAVNCHHNYVQKERHFGEDILVTRKGAVSAKKGELGIIPGSMGAK
SFIVRGLGNEESFCSCSHGAGRTMSRTKAKNTFTVEDQIRATAHVECRKDAAVIDEIPMAYKDIDKVMHAQRELVEVLHT
LRQVVCVKG

Sequences:

>Translated_409_residues
MMKEHTYQLLEVANGKPIKLWTEGVPVENEAREQLMNTAKMPFIFKHLAVMPDVHLGKGSTIGSVIPTVGAIIPAAVGVD
IGCGMIAARTSLTAADLPDNLHGLRSAIEQAVPHGRSSTRSRRDKGAWDEIPQQADQAWAALNPRFKAITDKYPKLANTN
NRGHLGTLGSGNHFIEVCLDEANRVWFMLHSGSRGVGNAIGNLFIQMAQADMRQHIANLPDRDLAYFEEGSRHFDDYVEA
VGWAQDFAKQNRALMMQAVIQATRQIIRKPFEVALEAVNCHHNYVQKERHFGEDILVTRKGAVSAKKGELGIIPGSMGAK
SFIVRGLGNEESFCSCSHGAGRTMSRTKAKNTFTVEDQIRATAHVECRKDAAVIDEIPMAYKDIDKVMHAQRELVEVLHT
LRQVVCVKG
>Mature_409_residues
MMKEHTYQLLEVANGKPIKLWTEGVPVENEAREQLMNTAKMPFIFKHLAVMPDVHLGKGSTIGSVIPTVGAIIPAAVGVD
IGCGMIAARTSLTAADLPDNLHGLRSAIEQAVPHGRSSTRSRRDKGAWDEIPQQADQAWAALNPRFKAITDKYPKLANTN
NRGHLGTLGSGNHFIEVCLDEANRVWFMLHSGSRGVGNAIGNLFIQMAQADMRQHIANLPDRDLAYFEEGSRHFDDYVEA
VGWAQDFAKQNRALMMQAVIQATRQIIRKPFEVALEAVNCHHNYVQKERHFGEDILVTRKGAVSAKKGELGIIPGSMGAK
SFIVRGLGNEESFCSCSHGAGRTMSRTKAKNTFTVEDQIRATAHVECRKDAAVIDEIPMAYKDIDKVMHAQRELVEVLHT
LRQVVCVKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=450, Percent_Identity=26.6666666666667, Blast_Score=122, Evalue=8e-28,
Organism=Escherichia coli, GI2367224, Length=407, Percent_Identity=70.5159705159705, Blast_Score=614, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI17506665, Length=431, Percent_Identity=26.9141531322506, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24585217, Length=425, Percent_Identity=27.5294117647059, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 45121; Mature: 45121

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKEHTYQLLEVANGKPIKLWTEGVPVENEAREQLMNTAKMPFIFKHLAVMPDVHLGKGS
CCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
TIGSVIPTVGAIIPAAVGVDIGCGMIAARTSLTAADLPDNLHGLRSAIEQAVPHGRSSTR
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCCCCHHH
SRRDKGAWDEIPQQADQAWAALNPRFKAITDKYPKLANTNNRGHLGTLGSGNHFIEVCLD
HHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEC
EANRVWFMLHSGSRGVGNAIGNLFIQMAQADMRQHIANLPDRDLAYFEEGSRHFDDYVEA
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHH
VGWAQDFAKQNRALMMQAVIQATRQIIRKPFEVALEAVNCHHNYVQKERHFGEDILVTRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GAVSAKKGELGIIPGSMGAKSFIVRGLGNEESFCSCSHGAGRTMSRTKAKNTFTVEDQIR
CCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEHHHHH
ATAHVECRKDAAVIDEIPMAYKDIDKVMHAQRELVEVLHTLRQVVCVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMKEHTYQLLEVANGKPIKLWTEGVPVENEAREQLMNTAKMPFIFKHLAVMPDVHLGKGS
CCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
TIGSVIPTVGAIIPAAVGVDIGCGMIAARTSLTAADLPDNLHGLRSAIEQAVPHGRSSTR
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHCCCHHHHHHHHHHHHHCCCCCCHHH
SRRDKGAWDEIPQQADQAWAALNPRFKAITDKYPKLANTNNRGHLGTLGSGNHFIEVCLD
HHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEC
EANRVWFMLHSGSRGVGNAIGNLFIQMAQADMRQHIANLPDRDLAYFEEGSRHFDDYVEA
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHH
VGWAQDFAKQNRALMMQAVIQATRQIIRKPFEVALEAVNCHHNYVQKERHFGEDILVTRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
GAVSAKKGELGIIPGSMGAKSFIVRGLGNEESFCSCSHGAGRTMSRTKAKNTFTVEDQIR
CCCCCCCCCEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEHHHHH
ATAHVECRKDAAVIDEIPMAYKDIDKVMHAQRELVEVLHTLRQVVCVKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9738023 [H]