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The map label for this gene is rbsK [H]

Identifier: 77458150

GI number: 77458150

Start: 2195658

End: 2196575

Strand: Direct

Name: rbsK [H]

Synonym: Pfl01_1923

Alternate gene names: 77458150

Gene position: 2195658-2196575 (Clockwise)

Preceding gene: 77458149

Following gene: 77458151

Centisome position: 34.1

GC content: 63.4

Gene sequence:

>918_bases
ATGTCCGCAAATGTAGTGGTAATAGGCAGCCTGAACATGGACCTGGTCACCCGGGCGCCGCGCTTGCCCCGGGGCGGTGA
GACGCTGATCGGTCATTCCTTCGCGACCGTGTCCGGTGGCAAGGGCGCCAATCAGGCGGTGGCCGCTGCGCGACTGGGTG
CGCAAGTGTCGATGGTCGGCTGTGTCGGCAACGATGAATATGGCGTGCAATTGCACGACGCGTTGCTGGCCGAGCAGATC
GATTGCCAGGCGGTCAGCGTGGTGGAGGATTCCAGTGGTGTGGCCTTGATCGTGGTCGATGACAACAGTCAGAACGCGAT
TGTCATCGTTGCCGGCGCCAATGGTTCGATGACCCCGGCGGTCATCGACCGGTTCGACGCCGTGCTGCAGGCTGCCGACG
TGATCATCTGCCAGCTGGAAATCCCCGATGCCACGGTGGGCCATGCGCTGAAACGCGGGCATGAACTGGGCAAGATGGTC
ATCCTCAACCCGGCGCCGGCCAGTCGCCCGCTGCCGGTGGACTGGTTTGCCGCCATCGATTACCTGATTCCCAACGAGAG
CGAGGCCGCCGCCCTCTGCGGTTTGCCGGTGGACTCGCTGGAGACCGCTGAAAAAGCCGCGGCGCACCTGATTTCACTGG
GCGCCGGCAAGGTCATCATCACGCTGGGCGCTCAAGGCTCTTTGTTCGCCAACGGTACGGGTTACCAGTATTTTCCTGCA
CCCAAAGTGAAGGCTGTCGACACCACCGCCGCCGGGGACACTTTTGTCGGCGGATTTGCCGCTGCACTGGCGGCCGGCAA
AACCGAGGACGAGGCCATTCGTTTCGGGCAGGTCGCTGCGGCCCTGTCGGTTACCCGGGCAGGTGCCCAGCCGTCCATTC
CCACCACCTCCGACGTACAGGCATTCAAACCCGCATGA

Upstream 100 bases:

>100_bases
AGCGGATCGTGACCCCGAGTATTGTCCTGCGCGAATCGACTGCACCGCTGTCCGGCGTGTTCACCGAATACCGCTGAAAC
GAATTGAAGAGTAGTGATGT

Downstream 100 bases:

>100_bases
AAAAGACTCCTTTGCTCAATGTCGCCCTGTCGCGGCTGATTGCCTCCCTCGGCCACGGCGACGTGGTCGTGATCGGTGAT
GCCGGCCTGCCGGTGCCGCC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSANVVVIGSLNMDLVTRAPRLPRGGETLIGHSFATVSGGKGANQAVAAARLGAQVSMVGCVGNDEYGVQLHDALLAEQI
DCQAVSVVEDSSGVALIVVDDNSQNAIVIVAGANGSMTPAVIDRFDAVLQAADVIICQLEIPDATVGHALKRGHELGKMV
ILNPAPASRPLPVDWFAAIDYLIPNESEAAALCGLPVDSLETAEKAAAHLISLGAGKVIITLGAQGSLFANGTGYQYFPA
PKVKAVDTTAAGDTFVGGFAAALAAGKTEDEAIRFGQVAAALSVTRAGAQPSIPTTSDVQAFKPA

Sequences:

>Translated_305_residues
MSANVVVIGSLNMDLVTRAPRLPRGGETLIGHSFATVSGGKGANQAVAAARLGAQVSMVGCVGNDEYGVQLHDALLAEQI
DCQAVSVVEDSSGVALIVVDDNSQNAIVIVAGANGSMTPAVIDRFDAVLQAADVIICQLEIPDATVGHALKRGHELGKMV
ILNPAPASRPLPVDWFAAIDYLIPNESEAAALCGLPVDSLETAEKAAAHLISLGAGKVIITLGAQGSLFANGTGYQYFPA
PKVKAVDTTAAGDTFVGGFAAALAAGKTEDEAIRFGQVAAALSVTRAGAQPSIPTTSDVQAFKPA
>Mature_304_residues
SANVVVIGSLNMDLVTRAPRLPRGGETLIGHSFATVSGGKGANQAVAAARLGAQVSMVGCVGNDEYGVQLHDALLAEQID
CQAVSVVEDSSGVALIVVDDNSQNAIVIVAGANGSMTPAVIDRFDAVLQAADVIICQLEIPDATVGHALKRGHELGKMVI
LNPAPASRPLPVDWFAAIDYLIPNESEAAALCGLPVDSLETAEKAAAHLISLGAGKVIITLGAQGSLFANGTGYQYFPAP
KVKAVDTTAAGDTFVGGFAAALAAGKTEDEAIRFGQVAAALSVTRAGAQPSIPTTSDVQAFKPA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=41.8918918918919, Blast_Score=181, Evalue=5e-46,
Organism=Escherichia coli, GI1790193, Length=301, Percent_Identity=43.8538205980066, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI87082343, Length=300, Percent_Identity=29.3333333333333, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87081971, Length=282, Percent_Identity=28.3687943262411, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788491, Length=285, Percent_Identity=24.2105263157895, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789775, Length=258, Percent_Identity=28.2945736434109, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788493, Length=286, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789432, Length=263, Percent_Identity=26.9961977186312, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=37.953795379538, Blast_Score=177, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI25147470, Length=270, Percent_Identity=26.2962962962963, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319884, Length=330, Percent_Identity=33.6363636363636, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322565, Length=286, Percent_Identity=32.1678321678322, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=39.7350993377483, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24583886, Length=299, Percent_Identity=34.1137123745819, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30981; Mature: 30849

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANVVVIGSLNMDLVTRAPRLPRGGETLIGHSFATVSGGKGANQAVAAARLGAQVSMVG
CCCCEEEEEECCHHHHHCCCCCCCCCCEEECCEEEEECCCCCCCHHHHHHHHCCEEEEEE
CVGNDEYGVQLHDALLAEQIDCQAVSVVEDSSGVALIVVDDNSQNAIVIVAGANGSMTPA
EECCCCCCEEEHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCHH
VIDRFDAVLQAADVIICQLEIPDATVGHALKRGHELGKMVILNPAPASRPLPVDWFAAID
HHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHH
YLIPNESEAAALCGLPVDSLETAEKAAAHLISLGAGKVIITLGAQGSLFANGTGYQYFPA
EECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCEECCC
PKVKAVDTTAAGDTFVGGFAAALAAGKTEDEAIRFGQVAAALSVTRAGAQPSIPTTSDVQ
CCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AFKPA
CCCCC
>Mature Secondary Structure 
SANVVVIGSLNMDLVTRAPRLPRGGETLIGHSFATVSGGKGANQAVAAARLGAQVSMVG
CCCEEEEEECCHHHHHCCCCCCCCCCEEECCEEEEECCCCCCCHHHHHHHHCCEEEEEE
CVGNDEYGVQLHDALLAEQIDCQAVSVVEDSSGVALIVVDDNSQNAIVIVAGANGSMTPA
EECCCCCCEEEHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCHH
VIDRFDAVLQAADVIICQLEIPDATVGHALKRGHELGKMVILNPAPASRPLPVDWFAAID
HHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHH
YLIPNESEAAALCGLPVDSLETAEKAAAHLISLGAGKVIITLGAQGSLFANGTGYQYFPA
EECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCEECCC
PKVKAVDTTAAGDTFVGGFAAALAAGKTEDEAIRFGQVAAALSVTRAGAQPSIPTTSDVQ
CCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AFKPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]