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The map label for this gene is aspC [H]

Identifier: 77458101

GI number: 77458101

Start: 2136084

End: 2137280

Strand: Reverse

Name: aspC [H]

Synonym: Pfl01_1874

Alternate gene names: 77458101

Gene position: 2137280-2136084 (Counterclockwise)

Preceding gene: 77458103

Following gene: 77458100

Centisome position: 33.2

GC content: 62.91

Gene sequence:

>1197_bases
ATGAGCCTGTTCTCCGCTGTCGAAATGGCACCCCGCGATCCAATCCTGGGCCTCAACGAAGCATTCAACGCCGATACCCG
GACCAACAAGGTCAACCTCGGGGTGGGTGTGTACTGCAACGAAGAGGGGCGAATTCCACTCCTGCGCGCCGTCATCGAAG
CCGAAACCATTCGCGCCGCTCAGCATGCCTCCCGTGGCTACCTGCCGATCGACGGCATCGCGGCCTACGACCAGGCTGTG
CAAAAGCTGCTGTTCGGCAATGATTCGCCACTGCTGGCGGCTGGCCGCGTTATCACCACTCAGGCCGTCGGCGGTACCGG
CGCACTGAAAATCGGTGCCGACTTCCTCAAGCAACTGCTGCCCAATGCCGTCGTGGCGATCAGCGACCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAAACCGCCGGTTTCCCGGTGCAGAACTACCGCTACTACGACGCCGCCACCCACGACGTGAAC
CGTGCCGGCCTGCTGGAAGACCTCAATGCCCTGCCGAACGGCTCGATCGTCGTGCTGCACGCCTGCTGCCACAATCCGAC
CGGCGTCGACCTGAGCCCGGCGGACTGGAACAACGTGCTGGAGGCGGTCAAGGCCAAAGGTCACGTGCCGTTCCTCGACA
TGGCTTACCAGGGTTTCGGTGACGGCATCGCCGAAGACGCCGCTGCCGTGCGTCTGTTCGCGGAATCCGGTCTGACCTTC
TTCGTATCGAGCTCGTTCTCCAAGTCGTTCTCGTTGTACGGCGAGCGCGTCGGTGCACTGTCGATCATCAGCGAATCGAA
AGAAGAAAGCGCCCGCGTCCTGTCGCAAGTCAAACGCGTGATCCGCACCAACTACTCCAACCCGCCGACCCACGGCGCAA
GCATCGTTGCCGCTGTGCTGAACAGCCCGGAACTGCGCGCTCAGTGGGAAGCCGAACTGGCTGAAATGCGCCTGCGCATT
CGCGGCATGCGCGAGCAGATGGTTGCTCTGCTGGCCAAGAAAGCCCCGCAGCGTGACTTCAGCTTCGTCGGTCGCCAGCG
CGGCATGTTCTCCTACTCCGGCCTGACCACCGAACAGGTTCACCGCCTGCGCAACGAGTTCGGCATCTACGCCCTGGACA
CCGGCCGCATCTGCGTCGCCGCGCTGAACCAGAGCAACATCGAAGCCGTGACGGACGCCATCGTTCAGGTCATCTGA

Upstream 100 bases:

>100_bases
GATGATGGCCTCTATACTAGCTCCCCGTTTGTGCACCGCTCTAGTGCATTCGGCTGGAGCGCCACACGTCCCTCCACTCT
CCATTAGAGCTGCCGTAAAA

Downstream 100 bases:

>100_bases
TCCGGCGTGGCACTGAAAACGGGAAGCCTTCGCGCTTCCCGTTTTTTATTTGTCTGAAGAAAAGCCGCCATACCCTCTAG
ACTGCACCCAAACGATATTT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSLFSAVEMAPRDPILGLNEAFNADTRTNKVNLGVGVYCNEEGRIPLLRAVIEAETIRAAQHASRGYLPIDGIAAYDQAV
QKLLFGNDSPLLAAGRVITTQAVGGTGALKIGADFLKQLLPNAVVAISDPSWENHRALFETAGFPVQNYRYYDAATHDVN
RAGLLEDLNALPNGSIVVLHACCHNPTGVDLSPADWNNVLEAVKAKGHVPFLDMAYQGFGDGIAEDAAAVRLFAESGLTF
FVSSSFSKSFSLYGERVGALSIISESKEESARVLSQVKRVIRTNYSNPPTHGASIVAAVLNSPELRAQWEAELAEMRLRI
RGMREQMVALLAKKAPQRDFSFVGRQRGMFSYSGLTTEQVHRLRNEFGIYALDTGRICVAALNQSNIEAVTDAIVQVI

Sequences:

>Translated_398_residues
MSLFSAVEMAPRDPILGLNEAFNADTRTNKVNLGVGVYCNEEGRIPLLRAVIEAETIRAAQHASRGYLPIDGIAAYDQAV
QKLLFGNDSPLLAAGRVITTQAVGGTGALKIGADFLKQLLPNAVVAISDPSWENHRALFETAGFPVQNYRYYDAATHDVN
RAGLLEDLNALPNGSIVVLHACCHNPTGVDLSPADWNNVLEAVKAKGHVPFLDMAYQGFGDGIAEDAAAVRLFAESGLTF
FVSSSFSKSFSLYGERVGALSIISESKEESARVLSQVKRVIRTNYSNPPTHGASIVAAVLNSPELRAQWEAELAEMRLRI
RGMREQMVALLAKKAPQRDFSFVGRQRGMFSYSGLTTEQVHRLRNEFGIYALDTGRICVAALNQSNIEAVTDAIVQVI
>Mature_397_residues
SLFSAVEMAPRDPILGLNEAFNADTRTNKVNLGVGVYCNEEGRIPLLRAVIEAETIRAAQHASRGYLPIDGIAAYDQAVQ
KLLFGNDSPLLAAGRVITTQAVGGTGALKIGADFLKQLLPNAVVAISDPSWENHRALFETAGFPVQNYRYYDAATHDVNR
AGLLEDLNALPNGSIVVLHACCHNPTGVDLSPADWNNVLEAVKAKGHVPFLDMAYQGFGDGIAEDAAAVRLFAESGLTFF
VSSSFSKSFSLYGERVGALSIISESKEESARVLSQVKRVIRTNYSNPPTHGASIVAAVLNSPELRAQWEAELAEMRLRIR
GMREQMVALLAKKAPQRDFSFVGRQRGMFSYSGLTTEQVHRLRNEFGIYALDTGRICVAALNQSNIEAVTDAIVQVI

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=397, Percent_Identity=45.088161209068, Blast_Score=351, Evalue=5e-97,
Organism=Homo sapiens, GI4504067, Length=405, Percent_Identity=40.7407407407407, Blast_Score=305, Evalue=4e-83,
Organism=Homo sapiens, GI117414139, Length=381, Percent_Identity=28.8713910761155, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=52.1410579345088, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=46.4646464646465, Blast_Score=381, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71981858, Length=398, Percent_Identity=40.2010050251256, Blast_Score=330, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI25147133, Length=397, Percent_Identity=42.0654911838791, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17569539, Length=401, Percent_Identity=38.1546134663342, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI17569537, Length=396, Percent_Identity=32.5757575757576, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=40.8450704225352, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17550384, Length=268, Percent_Identity=33.955223880597, Blast_Score=164, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=37.9310344827586, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=431, Percent_Identity=31.7865429234339, Blast_Score=234, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=42.964824120603, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=42.964824120603, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=42.9667519181586, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI19922362, Length=398, Percent_Identity=39.6984924623116, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24654046, Length=398, Percent_Identity=39.6984924623116, Blast_Score=308, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43182; Mature: 43050

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVEMAPRDPILGLNEAFNADTRTNKVNLGVGVYCNEEGRIPLLRAVIEAETIRAA
CCHHHHHHCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
QHASRGYLPIDGIAAYDQAVQKLLFGNDSPLLAAGRVITTQAVGGTGALKIGADFLKQLL
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHC
PNAVVAISDPSWENHRALFETAGFPVQNYRYYDAATHDVNRAGLLEDLNALPNGSIVVLH
CCCEEEECCCCCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEE
ACCHNPTGVDLSPADWNNVLEAVKAKGHVPFLDMAYQGFGDGIAEDAAAVRLFAESGLTF
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEE
FVSSSFSKSFSLYGERVGALSIISESKEESARVLSQVKRVIRTNYSNPPTHGASIVAAVL
EEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
NSPELRAQWEAELAEMRLRIRGMREQMVALLAKKAPQRDFSFVGRQRGMFSYSGLTTEQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCHHHH
HRLRNEFGIYALDTGRICVAALNQSNIEAVTDAIVQVI
HHHHHHCCEEEECCCCEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SLFSAVEMAPRDPILGLNEAFNADTRTNKVNLGVGVYCNEEGRIPLLRAVIEAETIRAA
CHHHHHHCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
QHASRGYLPIDGIAAYDQAVQKLLFGNDSPLLAAGRVITTQAVGGTGALKIGADFLKQLL
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHC
PNAVVAISDPSWENHRALFETAGFPVQNYRYYDAATHDVNRAGLLEDLNALPNGSIVVLH
CCCEEEECCCCCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEE
ACCHNPTGVDLSPADWNNVLEAVKAKGHVPFLDMAYQGFGDGIAEDAAAVRLFAESGLTF
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEE
FVSSSFSKSFSLYGERVGALSIISESKEESARVLSQVKRVIRTNYSNPPTHGASIVAAVL
EEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
NSPELRAQWEAELAEMRLRIRGMREQMVALLAKKAPQRDFSFVGRQRGMFSYSGLTTEQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCHHHH
HRLRNEFGIYALDTGRICVAALNQSNIEAVTDAIVQVI
HHHHHHCCEEEECCCCEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]