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The map label for this gene is yhdY [H]

Identifier: 77458094

GI number: 77458094

Start: 2129675

End: 2131117

Strand: Direct

Name: yhdY [H]

Synonym: Pfl01_1867

Alternate gene names: 77458094

Gene position: 2129675-2131117 (Clockwise)

Preceding gene: 77458093

Following gene: 77458095

Centisome position: 33.08

GC content: 61.47

Gene sequence:

>1443_bases
ATGCTGTCTCTGCTCACCGATCATCCGTTGTTTTGTGCCCTGATCCTGATCCTGGTCGATCTCGGTCTGTGGCGCCTGAT
CAGCGCCCACGGCAGTGCATGGAAACTGTTGGTGCGGGTGCTGATTTTTGCCCTGTTCAGCATTCTGCTGTTCAACGAAG
GGCTCAACCCGATGGAGCCTGCGCCTTGGGCCGACAATGTGCCGTTGCACCTGGCGGCGACCGGGTTGCAGATCGGCTGG
TGGCTGTTCGGCGCGCGCACTCTGACGGTGCTGATTGGTGCGGTGATGATGCAGCGTGTCGGGCATACCGGGCGGTTGTT
GCAGGATCTGCTCGGTGCGGTGATCTTCCTGATTGCGATCATCGCGGCGCTGGCCTACGTGCTGGATCTGCCGGTCAAAG
GCGTGCTGGCAACGTCCGGGGCGTTGGCGATCATCGTCGGTCTGGCGCTGCAGAGCACCTTGAGTGACGTGTTTTCCGGG
ATCGTGCTCAACACCACCAAGCCTTATCAACTGGATGACTGGATCTCCATCGACGGCACCGAAGGCCGGGTCACCGACAT
CGACTGGCGCGCCACGCGCCTGCAAACCAGTCAGGGCAGCATGGCGGTGATTCCCAACTCGCTGGCGGCCAAGGCCAAGA
TCATCAACTTCAGCCGGCCGAGCAACATGTTCGGGGTTGCCGTCAGCGTGCAGGTCAGCCCCCATGCGCGGCCGAGTTCG
GTGATCGATGCCCTGGAGCGCGCGATGCAGGGCTGTCGCCAACTGCTGGAGAACCCCGCGCCGAGTGTTGCGCTGAAGAG
CTCCAGCAGTGCAGGCACCGAATATGAAATCAGCGGGTTCGTCGCCTCGATGAGTGAAAAGCGCGTGGTGCGCAATCAGC
TGTTCGACCTGGCCTACCGGCATCTGCAAGCGTCCGGGGTCAATCTGCTCTCGAGTGATGAGCCGGGTGTTCCGAGCAAT
CTCTCGCGACCTCGGGCGTTGCTCGACAGCTCGCCGATTTTCTCCACCCTGCGTCAGGAGGAGAAAGAAACCTTCAGCCA
GAACATGACTCTGCAAACCTTCCGTGCCGGCGAGATGATTCTGGCGGGCGGGGAGGTCAGCGATCACCTGTTCATCATTG
AGTCCGGCGTGGTCTCGGTGACGCTCAAGCGCCACGGCACGCCGTTCGAGTCCGGACGGATGGGGCCGGGCGAAGTGATC
GGCGAGGCGGGGATTGTGTCCGATACCTCTTTGCCGGCCGACTTCTCCGCCAAGACCTTCTGCGCGCTGTACCGCATCGA
GAAGTCTTATCTCAAGCCATGCCTGGACGCCCGTCACGACATCAACGATGCGATGAAGGCGCTGCTCGATTTCCGCCTGC
ACAAGGCGCAATCCCTGACGGAAGATACGCCGGCGGTCGTGCCGAAAAAAGGCTTCCTTCAATGGCTGCGCAATCGCGTG
TAA

Upstream 100 bases:

>100_bases
TGCGCACGCGCAGTGGCGCTCATCCCGCCAAATCAATTACTCCTACACTGAGCCCAATCTGTGCGATCTTCTCGCGACTG
GCCCCTGTCGGAGTTGTTTG

Downstream 100 bases:

>100_bases
ACGGAGGATCCAACGCAACCGTCGCGGGGGGACCGGTGTCACAGGTTTTAATCGGTCAATGGCAGGAGCCCGGACGATGA
AAAAAATGCGCATTGCCACG

Product: cyclic nucleotide-regulated small mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MLSLLTDHPLFCALILILVDLGLWRLISAHGSAWKLLVRVLIFALFSILLFNEGLNPMEPAPWADNVPLHLAATGLQIGW
WLFGARTLTVLIGAVMMQRVGHTGRLLQDLLGAVIFLIAIIAALAYVLDLPVKGVLATSGALAIIVGLALQSTLSDVFSG
IVLNTTKPYQLDDWISIDGTEGRVTDIDWRATRLQTSQGSMAVIPNSLAAKAKIINFSRPSNMFGVAVSVQVSPHARPSS
VIDALERAMQGCRQLLENPAPSVALKSSSSAGTEYEISGFVASMSEKRVVRNQLFDLAYRHLQASGVNLLSSDEPGVPSN
LSRPRALLDSSPIFSTLRQEEKETFSQNMTLQTFRAGEMILAGGEVSDHLFIIESGVVSVTLKRHGTPFESGRMGPGEVI
GEAGIVSDTSLPADFSAKTFCALYRIEKSYLKPCLDARHDINDAMKALLDFRLHKAQSLTEDTPAVVPKKGFLQWLRNRV

Sequences:

>Translated_480_residues
MLSLLTDHPLFCALILILVDLGLWRLISAHGSAWKLLVRVLIFALFSILLFNEGLNPMEPAPWADNVPLHLAATGLQIGW
WLFGARTLTVLIGAVMMQRVGHTGRLLQDLLGAVIFLIAIIAALAYVLDLPVKGVLATSGALAIIVGLALQSTLSDVFSG
IVLNTTKPYQLDDWISIDGTEGRVTDIDWRATRLQTSQGSMAVIPNSLAAKAKIINFSRPSNMFGVAVSVQVSPHARPSS
VIDALERAMQGCRQLLENPAPSVALKSSSSAGTEYEISGFVASMSEKRVVRNQLFDLAYRHLQASGVNLLSSDEPGVPSN
LSRPRALLDSSPIFSTLRQEEKETFSQNMTLQTFRAGEMILAGGEVSDHLFIIESGVVSVTLKRHGTPFESGRMGPGEVI
GEAGIVSDTSLPADFSAKTFCALYRIEKSYLKPCLDARHDINDAMKALLDFRLHKAQSLTEDTPAVVPKKGFLQWLRNRV
>Mature_480_residues
MLSLLTDHPLFCALILILVDLGLWRLISAHGSAWKLLVRVLIFALFSILLFNEGLNPMEPAPWADNVPLHLAATGLQIGW
WLFGARTLTVLIGAVMMQRVGHTGRLLQDLLGAVIFLIAIIAALAYVLDLPVKGVLATSGALAIIVGLALQSTLSDVFSG
IVLNTTKPYQLDDWISIDGTEGRVTDIDWRATRLQTSQGSMAVIPNSLAAKAKIINFSRPSNMFGVAVSVQVSPHARPSS
VIDALERAMQGCRQLLENPAPSVALKSSSSAGTEYEISGFVASMSEKRVVRNQLFDLAYRHLQASGVNLLSSDEPGVPSN
LSRPRALLDSSPIFSTLRQEEKETFSQNMTLQTFRAGEMILAGGEVSDHLFIIESGVVSVTLKRHGTPFESGRMGPGEVI
GEAGIVSDTSLPADFSAKTFCALYRIEKSYLKPCLDARHDINDAMKALLDFRLHKAQSLTEDTPAVVPKKGFLQWLRNRV

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=170, Percent_Identity=24.7058823529412, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789291, Length=140, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 52152; Mature: 52152

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLLTDHPLFCALILILVDLGLWRLISAHGSAWKLLVRVLIFALFSILLFNEGLNPMEP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APWADNVPLHLAATGLQIGWWLFGARTLTVLIGAVMMQRVGHTGRLLQDLLGAVIFLIAI
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAALAYVLDLPVKGVLATSGALAIIVGLALQSTLSDVFSGIVLNTTKPYQLDDWISIDGT
HHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEECCC
EGRVTDIDWRATRLQTSQGSMAVIPNSLAAKAKIINFSRPSNMFGVAVSVQVSPHARPSS
CCCEEECCCHHHEEECCCCCEEECCCHHHHHHHEEECCCCCCCEEEEEEEEECCCCCHHH
VIDALERAMQGCRQLLENPAPSVALKSSSSAGTEYEISGFVASMSEKRVVRNQLFDLAYR
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
HLQASGVNLLSSDEPGVPSNLSRPRALLDSSPIFSTLRQEEKETFSQNMTLQTFRAGEMI
HHHHCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEE
LAGGEVSDHLFIIESGVVSVTLKRHGTPFESGRMGPGEVIGEAGIVSDTSLPADFSAKTF
EECCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHH
CALYRIEKSYLKPCLDARHDINDAMKALLDFRLHKAQSLTEDTPAVVPKKGFLQWLRNRV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLSLLTDHPLFCALILILVDLGLWRLISAHGSAWKLLVRVLIFALFSILLFNEGLNPMEP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
APWADNVPLHLAATGLQIGWWLFGARTLTVLIGAVMMQRVGHTGRLLQDLLGAVIFLIAI
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAALAYVLDLPVKGVLATSGALAIIVGLALQSTLSDVFSGIVLNTTKPYQLDDWISIDGT
HHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCEEECCC
EGRVTDIDWRATRLQTSQGSMAVIPNSLAAKAKIINFSRPSNMFGVAVSVQVSPHARPSS
CCCEEECCCHHHEEECCCCCEEECCCHHHHHHHEEECCCCCCCEEEEEEEEECCCCCHHH
VIDALERAMQGCRQLLENPAPSVALKSSSSAGTEYEISGFVASMSEKRVVRNQLFDLAYR
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
HLQASGVNLLSSDEPGVPSNLSRPRALLDSSPIFSTLRQEEKETFSQNMTLQTFRAGEMI
HHHHCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEE
LAGGEVSDHLFIIESGVVSVTLKRHGTPFESGRMGPGEVIGEAGIVSDTSLPADFSAKTF
EECCCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHH
CALYRIEKSYLKPCLDARHDINDAMKALLDFRLHKAQSLTEDTPAVVPKKGFLQWLRNRV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]