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The map label for this gene is pkn1 [H]

Identifier: 77458078

GI number: 77458078

Start: 2106936

End: 2107847

Strand: Reverse

Name: pkn1 [H]

Synonym: Pfl01_1851

Alternate gene names: 77458078

Gene position: 2107847-2106936 (Counterclockwise)

Preceding gene: 77458079

Following gene: 77458077

Centisome position: 32.74

GC content: 64.91

Gene sequence:

>912_bases
ATGATGAACAGTGAGCTACGTAGTTTTTCCATCAAGTCGCTCCCCGCGCTGACCCTGGCCGCCCTGCTCGCCAGCCTGTT
GCCGGGACTGGCGCAGGCGGCTGAACCGCTGCAGCCGGGCAAGGTGTTCAAAGACTGCAAGGACTGCCCGGAAATGGTCG
TGCTGCCCACCGGCACGTTCACCATGGGCACCCCGGAAGACGAAGTCGGCCGCGAACCGGACGAAGGCCCGATGCACCCG
GTGACGTTCGCCAAACCGCTGGCCATCAGCCGCTTTCAGGTCCTTCGGGGCCAATGGGACGCCTATCTCAAGGACACCGG
TTATCAGATGCCCGACGGCGATGATCGCGAGGGCCGCGCGTGCAAGGCCGGGATTCCGGATTACGCGGGCAGCGATCCGC
GCAAGCAGTACACCGACAAGCATCCGGCCGTGTGCATGGACTTCGCCGAAGTCAACGCGTACGTGGCGTGGCTCTCGAAA
AAGACCGGCAAGCAATACCGTCTGGTCAGTGAGTCCCTGCGCGAATACGCCGCGCGTGCCGGCAGCGCCGGGCCCTTCCC
GTTCCCGTTCGATGAGGGCAAGGAATACAGCATCGCCAAACACGCCAACACCTACGGCGCCGCCGATGGCTACAACTTTA
CCGCGCCGGCCGGCAGCTTTCCGGCCAACGCCTTCGGCGTCTATGACATGCACGGCAACGTCTACGAATGGACCGCTGAC
TGCTACAACGAAAACTACGCCGGTGCCCCGAGTGACGGCAGCGCGTGGCTGACCGGCGACTGCAGCATCCGGCGCATCCG
CGGCAATGACTGGGGCGAGGCGCCGGTGTTCTCGCGCTCCGGCAACCGCAACGCGGTCTACCCCAAAGTGCGGGGCGACT
GGCTGGGCTTTCGTGTAGCCCGCGACCTCTGA

Upstream 100 bases:

>100_bases
GGGCCTGTTGAACACCGAACAAGAAATCGACCGTTTCATGACCGTGCTCGTCAGCCAGATCTGAGCACCGTGAACGCCTT
TAAACCTGTTATCGAGAGAA

Downstream 100 bases:

>100_bases
TCCACCCCGGCGTCGACCATCGGGTCGACGCCTTCCCGGTTTTTCTCGAATCATCGCCCCCAGCGGCCTTCAAAAGCGGA
ATCCACCATGACCACTAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MMNSELRSFSIKSLPALTLAALLASLLPGLAQAAEPLQPGKVFKDCKDCPEMVVLPTGTFTMGTPEDEVGREPDEGPMHP
VTFAKPLAISRFQVLRGQWDAYLKDTGYQMPDGDDREGRACKAGIPDYAGSDPRKQYTDKHPAVCMDFAEVNAYVAWLSK
KTGKQYRLVSESLREYAARAGSAGPFPFPFDEGKEYSIAKHANTYGAADGYNFTAPAGSFPANAFGVYDMHGNVYEWTAD
CYNENYAGAPSDGSAWLTGDCSIRRIRGNDWGEAPVFSRSGNRNAVYPKVRGDWLGFRVARDL

Sequences:

>Translated_303_residues
MMNSELRSFSIKSLPALTLAALLASLLPGLAQAAEPLQPGKVFKDCKDCPEMVVLPTGTFTMGTPEDEVGREPDEGPMHP
VTFAKPLAISRFQVLRGQWDAYLKDTGYQMPDGDDREGRACKAGIPDYAGSDPRKQYTDKHPAVCMDFAEVNAYVAWLSK
KTGKQYRLVSESLREYAARAGSAGPFPFPFDEGKEYSIAKHANTYGAADGYNFTAPAGSFPANAFGVYDMHGNVYEWTAD
CYNENYAGAPSDGSAWLTGDCSIRRIRGNDWGEAPVFSRSGNRNAVYPKVRGDWLGFRVARDL
>Mature_303_residues
MMNSELRSFSIKSLPALTLAALLASLLPGLAQAAEPLQPGKVFKDCKDCPEMVVLPTGTFTMGTPEDEVGREPDEGPMHP
VTFAKPLAISRFQVLRGQWDAYLKDTGYQMPDGDDREGRACKAGIPDYAGSDPRKQYTDKHPAVCMDFAEVNAYVAWLSK
KTGKQYRLVSESLREYAARAGSAGPFPFPFDEGKEYSIAKHANTYGAADGYNFTAPAGSFPANAFGVYDMHGNVYEWTAD
CYNENYAGAPSDGSAWLTGDCSIRRIRGNDWGEAPVFSRSGNRNAVYPKVRGDWLGFRVARDL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=276, Percent_Identity=29.3478260869565, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI257470975, Length=206, Percent_Identity=26.6990291262136, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI194248088, Length=293, Percent_Identity=26.962457337884, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 33201; Mature: 33201

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNSELRSFSIKSLPALTLAALLASLLPGLAQAAEPLQPGKVFKDCKDCPEMVVLPTGTF
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCE
TMGTPEDEVGREPDEGPMHPVTFAKPLAISRFQVLRGQWDAYLKDTGYQMPDGDDREGRA
ECCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
CKAGIPDYAGSDPRKQYTDKHPAVCMDFAEVNAYVAWLSKKTGKQYRLVSESLREYAARA
EECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GSAGPFPFPFDEGKEYSIAKHANTYGAADGYNFTAPAGSFPANAFGVYDMHGNVYEWTAD
CCCCCCCCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEHH
CYNENYAGAPSDGSAWLTGDCSIRRIRGNDWGEAPVFSRSGNRNAVYPKVRGDWLGFRVA
HCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCEECCCCCCEECCCCCCCCEEEEEE
RDL
CCC
>Mature Secondary Structure
MMNSELRSFSIKSLPALTLAALLASLLPGLAQAAEPLQPGKVFKDCKDCPEMVVLPTGTF
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCE
TMGTPEDEVGREPDEGPMHPVTFAKPLAISRFQVLRGQWDAYLKDTGYQMPDGDDREGRA
ECCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
CKAGIPDYAGSDPRKQYTDKHPAVCMDFAEVNAYVAWLSKKTGKQYRLVSESLREYAARA
EECCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GSAGPFPFPFDEGKEYSIAKHANTYGAADGYNFTAPAGSFPANAFGVYDMHGNVYEWTAD
CCCCCCCCCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEHH
CYNENYAGAPSDGSAWLTGDCSIRRIRGNDWGEAPVFSRSGNRNAVYPKVRGDWLGFRVA
HCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCCEECCCCCCEECCCCCCCCEEEEEE
RDL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]