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The map label for this gene is cysH [H]

Identifier: 77457984

GI number: 77457984

Start: 1951962

End: 1952696

Strand: Reverse

Name: cysH [H]

Synonym: Pfl01_1757

Alternate gene names: 77457984

Gene position: 1952696-1951962 (Counterclockwise)

Preceding gene: 77457986

Following gene: 77457983

Centisome position: 30.33

GC content: 59.18

Gene sequence:

>735_bases
ATGAGCCCAACGTTCGACGTCGTGGAACTCGCCACGACCTATGCCAACAAATCCGCGCAGGACATCCTCAAACTCGCGTT
CGCCGAGTTCGGCGATGACCTGTGGATATCTTTCAGCGGCGCCGAGGATGTGGTGCTGGTGGACATGGCCTGGAAGCTGA
ACAAGAACGTCAAGGTGTTCAGTCTCGACACCGGCCGCCTGCATCCGGAAACCTACCGTTTCATCGATCAGGTGCGCGAG
CACTACAAGATCGACATCGAACTGGTCTCGCCGGACTACACGAAACTTGAACCGTTCGTGAAGGAAAAAGGCCTGTTCAG
TTTCTACAAGGACGGTCACGGCGAATGCTGCGGGATCCGCAAGATCGAGCCGCTGCGCCGCAAGCTGTCCGGCGTCAAAG
CCTGGGCCACCGGCCAGCGCCGCGATCAAAGCCCTGGCACCCGCAGCGCTGTGGCGGTGATGGAAATCGATACAGCGTTC
TCCACCCCGGAGCGCACCCTGTACAAGTTCAACCCGCTGGCACAGATGACCAGCGAGGAAATCTGGGGCTACATCCGCAT
GCTGGAGCTGCCGTACAACAGCCTGCACGAGCGCGGCTTTATCAGCATCGGCTGCGAACCGTGCACTCGTCCTGTCCTGC
CGAACCAGCACGAACGTGAAGGTCGCTGGTGGTGGGAAGAAGCGACCCAAAAAGAATGCGGGTTGCATGCCGGGAACATC
ATCAGCAAGGCATAA

Upstream 100 bases:

>100_bases
GAGCGCGCAACGCAGAGGCTGCCCCGGCGCGCGTTGCTTTTTGTTACCATCGCCGCCATATAGAGCGCCCAGCGCCACCG
ACCTGTAGGAAGCCGCCCTG

Downstream 100 bases:

>100_bases
GCATCCCTGTTGCCCTTTGGGAGCAAGTCAGCTCCCACAGTGTTCACCACCCGTTTTGAAAAATGTGTACACACGAATGT
CACCATCGGTGCCATTTATG

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSPTFDVVELATTYANKSAQDILKLAFAEFGDDLWISFSGAEDVVLVDMAWKLNKNVKVFSLDTGRLHPETYRFIDQVRE
HYKIDIELVSPDYTKLEPFVKEKGLFSFYKDGHGECCGIRKIEPLRRKLSGVKAWATGQRRDQSPGTRSAVAVMEIDTAF
STPERTLYKFNPLAQMTSEEIWGYIRMLELPYNSLHERGFISIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAGNI
ISKA

Sequences:

>Translated_244_residues
MSPTFDVVELATTYANKSAQDILKLAFAEFGDDLWISFSGAEDVVLVDMAWKLNKNVKVFSLDTGRLHPETYRFIDQVRE
HYKIDIELVSPDYTKLEPFVKEKGLFSFYKDGHGECCGIRKIEPLRRKLSGVKAWATGQRRDQSPGTRSAVAVMEIDTAF
STPERTLYKFNPLAQMTSEEIWGYIRMLELPYNSLHERGFISIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAGNI
ISKA
>Mature_243_residues
SPTFDVVELATTYANKSAQDILKLAFAEFGDDLWISFSGAEDVVLVDMAWKLNKNVKVFSLDTGRLHPETYRFIDQVREH
YKIDIELVSPDYTKLEPFVKEKGLFSFYKDGHGECCGIRKIEPLRRKLSGVKAWATGQRRDQSPGTRSAVAVMEIDTAFS
TPERTLYKFNPLAQMTSEEIWGYIRMLELPYNSLHERGFISIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAGNII
SKA

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=210, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6325425, Length=233, Percent_Identity=28.755364806867, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27986; Mature: 27855

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTFDVVELATTYANKSAQDILKLAFAEFGDDLWISFSGAEDVVLVDMAWKLNKNVKVF
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEECCCCEEEE
SLDTGRLHPETYRFIDQVREHYKIDIELVSPDYTKLEPFVKEKGLFSFYKDGHGECCGIR
EECCCCCCHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCEECCC
KIEPLRRKLSGVKAWATGQRRDQSPGTRSAVAVMEIDTAFSTPERTLYKFNPLAQMTSEE
CCHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEECCHHHHHHHH
IWGYIRMLELPYNSLHERGFISIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAGNI
HHHHHHHEECCHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
ISKA
CCCC
>Mature Secondary Structure 
SPTFDVVELATTYANKSAQDILKLAFAEFGDDLWISFSGAEDVVLVDMAWKLNKNVKVF
CCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEECCCCEEEE
SLDTGRLHPETYRFIDQVREHYKIDIELVSPDYTKLEPFVKEKGLFSFYKDGHGECCGIR
EECCCCCCHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCEECCC
KIEPLRRKLSGVKAWATGQRRDQSPGTRSAVAVMEIDTAFSTPERTLYKFNPLAQMTSEE
CCHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEECCHHHHHHHH
IWGYIRMLELPYNSLHERGFISIGCEPCTRPVLPNQHEREGRWWWEEATQKECGLHAGNI
HHHHHHHEECCHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
ISKA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA