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The map label for this gene is pabB [H]

Identifier: 77457986

GI number: 77457986

Start: 1953602

End: 1954945

Strand: Reverse

Name: pabB [H]

Synonym: Pfl01_1759

Alternate gene names: 77457986

Gene position: 1954945-1953602 (Counterclockwise)

Preceding gene: 77457987

Following gene: 77457984

Centisome position: 30.36

GC content: 61.98

Gene sequence:

>1344_bases
ATGTTGACCTGTTCCGTACACCCGCTGCCCTACCGCGCCAACCCCGCCGACTATTTTGCGGCCGTCCGCCATGCGCCCGG
CGCCGTGCTGCTCGACAGTGGCCGGCCGAGTGCCGATCGTGGCCGTTATGACTTGCTCAGCGCCTGGCCGCTGGAACAAC
TGGCGGTGTTGCCGGACGAGCGCGGAGAAGATTTCCTGCAACGCCTACGGACCAATCTGACCCGGTTGGGCGACGCGCAA
TTGCCCGACGACTACGAATTGCCTTTCGCTGGTGGCCTGATTGGTTACCTGAGCTACGACTTCGGCCGTCATCTGGAAAA
CCTGCCGAGTCAGGCCCTGGATGACCTGCAATTGCCCGATGCGCGATTTGGTCTGTACGACTGGGCCTTGATCAGCGATC
ACCAATCGGCCACCAGCCAACTTGTGTTCCACCCCTCAGTCAGCGCCAGCGAGAAACAGCGGTTGATCGATGTATTCAGC
CAACCGGTGGGCACGGAACTGACCCCATTCAAACTGAACAGCCCGATGGCAGCCGATCTCTCGGCCAATGAATACCGTCA
GGCGTTCGAACGTATCCAGCATTACATTCAGGCCGGCGACTGCTATCAGGTCAATTTCGCCCAGCGTTTCCGCGCGCCGT
GCCAGGGCGATCCATGGCTGGCCTACTGCAAATTGCGCGAGGCCTGCCCGACACCGTTTTCCGGGTTCCAGAGCCTGCCC
GACGGCAACGCAGTGCTGAGCGTGTCGCCCGAGCGTTTCGTCAAAGTCAGCCAGCGTCAGGTGGAAACCCGCCCGATCAA
GGGCACCCGTCCCCGTGGCGCGAACCCGACCGAGGACGCGGCGAACGCCGCCGAATTGCTGGCCAGCCCCAAGGATCGCG
CGGAAAACCTGATGATCGTCGACCTGCTGCGCAATGATCTGGGCCGCACCTGCCGTATCGGCTCGGTGCGAGTGCCAGAG
CTGTTCAGCCTGGAAAGCTATCCGAACGTGCATCACCTGGTCAGCAGCGTGACCGGCGAACTGGCGCAGGATCGCGACGC
CCTGGACCTGATTGCCGGCAGCTTCCCCGGCGGCTCGATCACCGGCGCACCGAAAATCCGTGCGATGCAGATCATCGATG
AGCTGGAGCCGACCCGGCGTGGTTTGTATTGCGGTTCGTTGCTGTATCTGGACGTGCGCGGCGAGATGGACAGCTCCATC
GCCATTCGCAGTCTGCTGGTGAAGGATGGACAAGTGTGTTGCTGGGGCGGTGGCGGAATCGTCGCCGATTCTGACTGGGA
AGCGGAGTATCAGGAATCGATCACCAAGGTCAGAGTCCTGCTCGAAACCCTGCAGAACCTCTGA

Upstream 100 bases:

>100_bases
TCCTGCCGCCGACCTGCCAATCCCCGACATCCCCTCTAGGAGCAATTCCCGGAGGGGACTACAATCCCCACCCCGCCTCG
ATGGCCGATCTGCCCCGCCC

Downstream 100 bases:

>100_bases
CGTTTGTTGATCGTTCCCACGCTCTGCGTGGGAATGCAGCCCGGGACGCTCTGCGTCCCAAAGCGGACGCAGAGCGTCCA
TTGAGGCATTCCCACGCAGA

Product: aminodeoxychorismate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MLTCSVHPLPYRANPADYFAAVRHAPGAVLLDSGRPSADRGRYDLLSAWPLEQLAVLPDERGEDFLQRLRTNLTRLGDAQ
LPDDYELPFAGGLIGYLSYDFGRHLENLPSQALDDLQLPDARFGLYDWALISDHQSATSQLVFHPSVSASEKQRLIDVFS
QPVGTELTPFKLNSPMAADLSANEYRQAFERIQHYIQAGDCYQVNFAQRFRAPCQGDPWLAYCKLREACPTPFSGFQSLP
DGNAVLSVSPERFVKVSQRQVETRPIKGTRPRGANPTEDAANAAELLASPKDRAENLMIVDLLRNDLGRTCRIGSVRVPE
LFSLESYPNVHHLVSSVTGELAQDRDALDLIAGSFPGGSITGAPKIRAMQIIDELEPTRRGLYCGSLLYLDVRGEMDSSI
AIRSLLVKDGQVCCWGGGGIVADSDWEAEYQESITKVRVLLETLQNL

Sequences:

>Translated_447_residues
MLTCSVHPLPYRANPADYFAAVRHAPGAVLLDSGRPSADRGRYDLLSAWPLEQLAVLPDERGEDFLQRLRTNLTRLGDAQ
LPDDYELPFAGGLIGYLSYDFGRHLENLPSQALDDLQLPDARFGLYDWALISDHQSATSQLVFHPSVSASEKQRLIDVFS
QPVGTELTPFKLNSPMAADLSANEYRQAFERIQHYIQAGDCYQVNFAQRFRAPCQGDPWLAYCKLREACPTPFSGFQSLP
DGNAVLSVSPERFVKVSQRQVETRPIKGTRPRGANPTEDAANAAELLASPKDRAENLMIVDLLRNDLGRTCRIGSVRVPE
LFSLESYPNVHHLVSSVTGELAQDRDALDLIAGSFPGGSITGAPKIRAMQIIDELEPTRRGLYCGSLLYLDVRGEMDSSI
AIRSLLVKDGQVCCWGGGGIVADSDWEAEYQESITKVRVLLETLQNL
>Mature_447_residues
MLTCSVHPLPYRANPADYFAAVRHAPGAVLLDSGRPSADRGRYDLLSAWPLEQLAVLPDERGEDFLQRLRTNLTRLGDAQ
LPDDYELPFAGGLIGYLSYDFGRHLENLPSQALDDLQLPDARFGLYDWALISDHQSATSQLVFHPSVSASEKQRLIDVFS
QPVGTELTPFKLNSPMAADLSANEYRQAFERIQHYIQAGDCYQVNFAQRFRAPCQGDPWLAYCKLREACPTPFSGFQSLP
DGNAVLSVSPERFVKVSQRQVETRPIKGTRPRGANPTEDAANAAELLASPKDRAENLMIVDLLRNDLGRTCRIGSVRVPE
LFSLESYPNVHHLVSSVTGELAQDRDALDLIAGSFPGGSITGAPKIRAMQIIDELEPTRRGLYCGSLLYLDVRGEMDSSI
AIRSLLVKDGQVCCWGGGGIVADSDWEAEYQESITKVRVLLETLQNL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=457, Percent_Identity=46.1706783369803, Blast_Score=387, Evalue=1e-108,
Organism=Escherichia coli, GI1787518, Length=380, Percent_Identity=35, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786809, Length=215, Percent_Identity=27.906976744186, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082077, Length=206, Percent_Identity=28.6407766990291, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=431, Percent_Identity=33.6426914153132, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6324361, Length=415, Percent_Identity=28.9156626506024, Blast_Score=149, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49423; Mature: 49423

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTCSVHPLPYRANPADYFAAVRHAPGAVLLDSGRPSADRGRYDLLSAWPLEQLAVLPDE
CEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHCCCHHHHHCCCCC
RGEDFLQRLRTNLTRLGDAQLPDDYELPFAGGLIGYLSYDFGRHLENLPSQALDDLQLPD
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCC
ARFGLYDWALISDHQSATSQLVFHPSVSASEKQRLIDVFSQPVGTELTPFKLNSPMAADL
CCCCCEEEEEECCCHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCC
SANEYRQAFERIQHYIQAGDCYQVNFAQRFRAPCQGDPWLAYCKLREACPTPFSGFQSLP
CHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHCCC
DGNAVLSVSPERFVKVSQRQVETRPIKGTRPRGANPTEDAANAAELLASPKDRAENLMIV
CCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEHH
DLLRNDLGRTCRIGSVRVPELFSLESYPNVHHLVSSVTGELAQDRDALDLIAGSFPGGSI
HHHHHHCCCEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
TGAPKIRAMQIIDELEPTRRGLYCGSLLYLDVRGEMDSSIAIRSLLVKDGQVCCWGGGGI
CCCCCHHHHHHHHHHCHHHCCEEECEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCE
VADSDWEAEYQESITKVRVLLETLQNL
EECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTCSVHPLPYRANPADYFAAVRHAPGAVLLDSGRPSADRGRYDLLSAWPLEQLAVLPDE
CEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHCCCHHHHHCCCCC
RGEDFLQRLRTNLTRLGDAQLPDDYELPFAGGLIGYLSYDFGRHLENLPSQALDDLQLPD
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCC
ARFGLYDWALISDHQSATSQLVFHPSVSASEKQRLIDVFSQPVGTELTPFKLNSPMAADL
CCCCCEEEEEECCCHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCC
SANEYRQAFERIQHYIQAGDCYQVNFAQRFRAPCQGDPWLAYCKLREACPTPFSGFQSLP
CHHHHHHHHHHHHHHHHCCCEEEECHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHCCC
DGNAVLSVSPERFVKVSQRQVETRPIKGTRPRGANPTEDAANAAELLASPKDRAENLMIV
CCCEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEHH
DLLRNDLGRTCRIGSVRVPELFSLESYPNVHHLVSSVTGELAQDRDALDLIAGSFPGGSI
HHHHHHCCCEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
TGAPKIRAMQIIDELEPTRRGLYCGSLLYLDVRGEMDSSIAIRSLLVKDGQVCCWGGGGI
CCCCCHHHHHHHHHHCHHHCCEEECEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCE
VADSDWEAEYQESITKVRVLLETLQNL
EECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]