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The map label for this gene is ycaN [H]

Identifier: 77457981

GI number: 77457981

Start: 1948175

End: 1949161

Strand: Direct

Name: ycaN [H]

Synonym: Pfl01_1754

Alternate gene names: 77457981

Gene position: 1948175-1949161 (Clockwise)

Preceding gene: 77457979

Following gene: 77457985

Centisome position: 30.26

GC content: 61.5

Gene sequence:

>987_bases
GTGGTTGCTATAGTCTGTGTAAACCAAAAGTTTAGAGTGGCGGCCATGGAAACCTTCAGCAGTATCGAATGCTTCGTGCG
CAGCGCCGAAGTCGGCAGCTTTGCCGAGGCCGCGCGACGACTGAGCCTGACACCGGCCGCCGTGGGCAAAAGCGTGGCGA
AACTGGAAGCGCGCCTCGGCGTGAGGCTGTTCCAGCGTAGCACCCGTCGCTTGACCCTGACGGAAGCGGGGCAATTGTTT
CTGAGTGAGGTCAGCGGCAGCCTGACCACCATCCAGAACGCGGTGAACAATCTGGCCAGTGCCGGCGGTCAACCGGCGGG
CACGCTGAAAGTCAGCATGGGTACGGTGTTCGGCCGTTTGTACATCGTGCCGTTGCTGGGGGAATTCCTGAAAAGATTTC
CGGCGATCAACCCGGACTGGCACTTCGATAACCGCCAGGTCGATCTGATCGGCCAGGGTTTCGATGCGGCGATTGGTGGA
GGCTTCGAACTGCCCCAAGGCGTGGTAGCGCGCAGGCTCACACCGGCGCATCGGGTGTTGGTGGCTTCTGCGGATTATCT
GGATCGATACGCGCCGATCAGCGAGCCGGACGACCTCAAGCTGCACGACGGCATCCTGATCCGCTCACCGCAGACCGGTC
GCGTGCGCTCCTGGCAGTTGACCCATCGCACCCGGCAACACAGCCCGCTGACCCTCAAGGCACGAATGACCATGAGTGAT
TCCGAAGCCGCCTGCGCCACGGCGGCGCAGGGGTTGGGGATTGCGTTGGTGAGCATGCCGTTTGCCGTCGGTTACCTTGA
GGTGGGGACCTTGCAGCGGGTCCTGCCGGACTGGTACGTCGACGACGGCAACATCTCCATTTATTACGCCGAACACAAAC
TGCTGCCGGGCAAGACCCGGGCGTTCGTCGATTTTGTCATCGAGCAGTTTTCAACCCTGGGCCTCGCCGAACGGTTCAAC
GCGCAAAACGTGCTGGCCAGCCAATGA

Upstream 100 bases:

>100_bases
CTGAGGTGTTGAGTGGTCATGTTCGATCTCCAGAAGTTTCAAGGCAGGCTGCCTTGGTGTGGTGTCGAGTATCTGCCCCT
CGCCAATAGGCGGGTAGACC

Downstream 100 bases:

>100_bases
TGGTTTTCGGCCGTGGCGTCGCATAGGTGCGCACCTTGGAGGTCGACAGGCCGAGGCGCACCAGCGATTCGGCAATGGTC
ACGGCCGCTGTGACGCCATC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MVAIVCVNQKFRVAAMETFSSIECFVRSAEVGSFAEAARRLSLTPAAVGKSVAKLEARLGVRLFQRSTRRLTLTEAGQLF
LSEVSGSLTTIQNAVNNLASAGGQPAGTLKVSMGTVFGRLYIVPLLGEFLKRFPAINPDWHFDNRQVDLIGQGFDAAIGG
GFELPQGVVARRLTPAHRVLVASADYLDRYAPISEPDDLKLHDGILIRSPQTGRVRSWQLTHRTRQHSPLTLKARMTMSD
SEAACATAAQGLGIALVSMPFAVGYLEVGTLQRVLPDWYVDDGNISIYYAEHKLLPGKTRAFVDFVIEQFSTLGLAERFN
AQNVLASQ

Sequences:

>Translated_328_residues
MVAIVCVNQKFRVAAMETFSSIECFVRSAEVGSFAEAARRLSLTPAAVGKSVAKLEARLGVRLFQRSTRRLTLTEAGQLF
LSEVSGSLTTIQNAVNNLASAGGQPAGTLKVSMGTVFGRLYIVPLLGEFLKRFPAINPDWHFDNRQVDLIGQGFDAAIGG
GFELPQGVVARRLTPAHRVLVASADYLDRYAPISEPDDLKLHDGILIRSPQTGRVRSWQLTHRTRQHSPLTLKARMTMSD
SEAACATAAQGLGIALVSMPFAVGYLEVGTLQRVLPDWYVDDGNISIYYAEHKLLPGKTRAFVDFVIEQFSTLGLAERFN
AQNVLASQ
>Mature_328_residues
MVAIVCVNQKFRVAAMETFSSIECFVRSAEVGSFAEAARRLSLTPAAVGKSVAKLEARLGVRLFQRSTRRLTLTEAGQLF
LSEVSGSLTTIQNAVNNLASAGGQPAGTLKVSMGTVFGRLYIVPLLGEFLKRFPAINPDWHFDNRQVDLIGQGFDAAIGG
GFELPQGVVARRLTPAHRVLVASADYLDRYAPISEPDDLKLHDGILIRSPQTGRVRSWQLTHRTRQHSPLTLKARMTMSD
SEAACATAAQGLGIALVSMPFAVGYLEVGTLQRVLPDWYVDDGNISIYYAEHKLLPGKTRAFVDFVIEQFSTLGLAERFN
AQNVLASQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=28.6206896551724, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=28.9198606271777, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786401, Length=301, Percent_Identity=28.9036544850498, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789639, Length=311, Percent_Identity=26.3665594855305, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=26.9896193771626, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=26.4604810996564, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=26.6211604095563, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789173, Length=289, Percent_Identity=26.2975778546713, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788706, Length=309, Percent_Identity=27.5080906148867, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786448, Length=127, Percent_Identity=30.7086614173228, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=31.8965517241379, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693105, Length=121, Percent_Identity=34.7107438016529, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=116, Percent_Identity=31.0344827586207, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=30, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35768; Mature: 35768

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAIVCVNQKFRVAAMETFSSIECFVRSAEVGSFAEAARRLSLTPAAVGKSVAKLEARLG
CEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VRLFQRSTRRLTLTEAGQLFLSEVSGSLTTIQNAVNNLASAGGQPAGTLKVSMGTVFGRL
HHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHH
YIVPLLGEFLKRFPAINPDWHFDNRQVDLIGQGFDAAIGGGFELPQGVVARRLTPAHRVL
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHHCCHHHHEE
VASADYLDRYAPISEPDDLKLHDGILIRSPQTGRVRSWQLTHRTRQHSPLTLKARMTMSD
EEEHHHHHHCCCCCCCCCCEEECCEEEECCCCCCCEEEEHHHHHCCCCCEEEEEEEEECC
SEAACATAAQGLGIALVSMPFAVGYLEVGTLQRVLPDWYVDDGNISIYYAEHKLLPGKTR
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCEECCCCHH
AFVDFVIEQFSTLGLAERFNAQNVLASQ
HHHHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MVAIVCVNQKFRVAAMETFSSIECFVRSAEVGSFAEAARRLSLTPAAVGKSVAKLEARLG
CEEEEEECCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VRLFQRSTRRLTLTEAGQLFLSEVSGSLTTIQNAVNNLASAGGQPAGTLKVSMGTVFGRL
HHHHHHCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHH
YIVPLLGEFLKRFPAINPDWHFDNRQVDLIGQGFDAAIGGGFELPQGVVARRLTPAHRVL
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHCCCCCCCCHHHHHHHCCHHHHEE
VASADYLDRYAPISEPDDLKLHDGILIRSPQTGRVRSWQLTHRTRQHSPLTLKARMTMSD
EEEHHHHHHCCCCCCCCCCEEECCEEEECCCCCCCEEEEHHHHHCCCCCEEEEEEEEECC
SEAACATAAQGLGIALVSMPFAVGYLEVGTLQRVLPDWYVDDGNISIYYAEHKLLPGKTR
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCEECCCCHH
AFVDFVIEQFSTLGLAERFNAQNVLASQ
HHHHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]