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The map label for this gene is yhcW [H]

Identifier: 77457979

GI number: 77457979

Start: 1946572

End: 1947270

Strand: Direct

Name: yhcW [H]

Synonym: Pfl01_1752

Alternate gene names: 77457979

Gene position: 1946572-1947270 (Clockwise)

Preceding gene: 77457976

Following gene: 77457981

Centisome position: 30.23

GC content: 61.37

Gene sequence:

>699_bases
ATGATGAATGCACCGCTGAAGGCGTTCGGCCCGATCAAGGCCGTGATTTTCGACATGGACGGTTTGCTGCTGGACACCGA
GGGCATCTACACCGAGGTTACCTCGCTGATTGCCGAGCGTTACGGGCGCACGTTCGATTGGAGCATCAAACAGAACATCA
TCGGGCGCGGCGCCGGCGATCTCGCGCGTTATGTGGTTGAAGCGCTGGACCTGCCGATCACCGCCGAAGAGTTTCTGGTG
ATCCGCGAGCCGCTGATGCGTGAGCGTTTTCCCACCGCGCAAGCGATGCCGGGCGCCGAGGAACTGATCCGCCACCTCAA
GGCGCACAACATTCCGATTGCGGTCGGCACCAGTTCGTCGCGTCAGTCGTTCGGTCAGAAAACCACCTTGCACCGCGACT
GGTTTGCGTTGTTCGACTTCATCGTCACCGCTGACGACCCGGAAGTCGGTGCGGCCAAACCGGCGCCGGACATCTTCCTC
ACCGCCGCTCGCCGCCTCGGTGTTGCGCCGGAAGATTGCCTGGTGTTTGAAGATTCGCCGTTCGGTGTGACAGCCGCGAA
AGCAGCCGGCATGACTGCCATCGCCATTCCCGATGCCGCCATGGCCGATGAAAAATACGCACACGCCGACGGGATTCTTC
GTACGTTGAAAGCGTTCACGCCGAGTGCTTGCGGGTTGCCGGCGCTCGACTGGGCTTGA

Upstream 100 bases:

>100_bases
GCTCAAACTCGGCCGTGCTCGTTATGCTGCTGAACCCTTTAATCAGATCCGAGCAGCGGCGCTATCCACGCCGCCCGGGA
TGTCTTTGATAACGGATCCG

Downstream 100 bases:

>100_bases
TCAAATCGCGAACAAAAAAAACGCCGCCCCTCTGTCAAAGGAGGGGCGGCGTTTTTCGTTATCGACTATCCGATCAATCA
GGCGCCGAAACCACCGTCGA

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MMNAPLKAFGPIKAVIFDMDGLLLDTEGIYTEVTSLIAERYGRTFDWSIKQNIIGRGAGDLARYVVEALDLPITAEEFLV
IREPLMRERFPTAQAMPGAEELIRHLKAHNIPIAVGTSSSRQSFGQKTTLHRDWFALFDFIVTADDPEVGAAKPAPDIFL
TAARRLGVAPEDCLVFEDSPFGVTAAKAAGMTAIAIPDAAMADEKYAHADGILRTLKAFTPSACGLPALDWA

Sequences:

>Translated_232_residues
MMNAPLKAFGPIKAVIFDMDGLLLDTEGIYTEVTSLIAERYGRTFDWSIKQNIIGRGAGDLARYVVEALDLPITAEEFLV
IREPLMRERFPTAQAMPGAEELIRHLKAHNIPIAVGTSSSRQSFGQKTTLHRDWFALFDFIVTADDPEVGAAKPAPDIFL
TAARRLGVAPEDCLVFEDSPFGVTAAKAAGMTAIAIPDAAMADEKYAHADGILRTLKAFTPSACGLPALDWA
>Mature_232_residues
MMNAPLKAFGPIKAVIFDMDGLLLDTEGIYTEVTSLIAERYGRTFDWSIKQNIIGRGAGDLARYVVEALDLPITAEEFLV
IREPLMRERFPTAQAMPGAEELIRHLKAHNIPIAVGTSSSRQSFGQKTTLHRDWFALFDFIVTADDPEVGAAKPAPDIFL
TAARRLGVAPEDCLVFEDSPFGVTAAKAAGMTAIAIPDAAMADEKYAHADGILRTLKAFTPSACGLPALDWA

Specific function: Unknown

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=222, Percent_Identity=45.045045045045, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI207113149, Length=245, Percent_Identity=40.8163265306122, Blast_Score=192, Evalue=2e-49,
Organism=Homo sapiens, GI296011028, Length=180, Percent_Identity=43.8888888888889, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI296011030, Length=222, Percent_Identity=38.2882882882883, Blast_Score=154, Evalue=5e-38,
Organism=Escherichia coli, GI1789046, Length=196, Percent_Identity=33.1632653061224, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787576, Length=194, Percent_Identity=27.8350515463918, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554716, Length=227, Percent_Identity=36.5638766519824, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17137324, Length=230, Percent_Identity=46.9565217391304, Blast_Score=199, Evalue=9e-52,
Organism=Drosophila melanogaster, GI116008157, Length=226, Percent_Identity=43.8053097345133, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI45550911, Length=225, Percent_Identity=39.5555555555556, Blast_Score=165, Evalue=3e-41,
Organism=Drosophila melanogaster, GI20129151, Length=228, Percent_Identity=35.0877192982456, Blast_Score=151, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24580849, Length=206, Percent_Identity=38.8349514563107, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI45550097, Length=224, Percent_Identity=28.125, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129149, Length=192, Percent_Identity=29.6875, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25151; Mature: 25151

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNAPLKAFGPIKAVIFDMDGLLLDTEGIYTEVTSLIAERYGRTFDWSIKQNIIGRGAGD
CCCCCCCHHCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHH
LARYVVEALDLPITAEEFLVIREPLMRERFPTAQAMPGAEELIRHLKAHNIPIAVGTSSS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCHH
RQSFGQKTTLHRDWFALFDFIVTADDPEVGAAKPAPDIFLTAARRLGVAPEDCLVFEDSP
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCC
FGVTAAKAAGMTAIAIPDAAMADEKYAHADGILRTLKAFTPSACGLPALDWA
CCEEHHHHCCEEEEECCCHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MMNAPLKAFGPIKAVIFDMDGLLLDTEGIYTEVTSLIAERYGRTFDWSIKQNIIGRGAGD
CCCCCCCHHCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHH
LARYVVEALDLPITAEEFLVIREPLMRERFPTAQAMPGAEELIRHLKAHNIPIAVGTSSS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCHH
RQSFGQKTTLHRDWFALFDFIVTADDPEVGAAKPAPDIFLTAARRLGVAPEDCLVFEDSP
HHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCC
FGVTAAKAAGMTAIAIPDAAMADEKYAHADGILRTLKAFTPSACGLPALDWA
CCEEHHHHCCEEEEECCCHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]