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The map label for this gene is cobO [H]

Identifier: 77457868

GI number: 77457868

Start: 1832434

End: 1833045

Strand: Direct

Name: cobO [H]

Synonym: Pfl01_1641

Alternate gene names: 77457868

Gene position: 1832434-1833045 (Clockwise)

Preceding gene: 77457865

Following gene: 77457869

Centisome position: 28.46

GC content: 61.44

Gene sequence:

>612_bases
ATGACTGATTCCCCCGAACGCGACGAGCGCCACCTGGCGCGCATGCAGCGCAAAAAAGCGGTGATCGACGAACGCATCGC
CAATTCGCCAGACGAGTGCGGGCTGGTGCTGGTGCTCACCGGCAATGGCAAAGGCAAGAGCAGTTCGGCATTCGGCATGC
TCGCCCGCGCCATGGGCCACGGCATGCAGTGCGGCGTGGTGCAGTTCATCAAGGGTCGCAACAGCACCGGCGAAGAGCTG
TTCTTCCGCCGCTTCCCTGAACAAGTACGTTTTCATGTGATGGGCGAAGGCTTCACCTGGGAAACCCAGGACCGCCAGCG
CGACATCGCCGCCGCCGAAGCGGCCTGGGAAGTCTCCCGCGAACTGCTGCGTGATCCGTCGATCGGTCTGGTGGTGCTCG
ATGAACTGAACATCGCCCTCAAGCACGGTTACCTCGATCTGGATCAGGTGCTCAGCGATCTGCAGGCCCGTCCGCCGATG
CAGCATGTGATCGTCACCGGTCGCGCTGCCAAGCCGGAAATGATCGAGATGGGCGACACCGTCACCGAAATGGGCATGAT
CAAGCACGCCTTCCAAGCCGGTATCAAAGCGCAGAAAGGCGTCGAACTTTGA

Upstream 100 bases:

>100_bases
CCTGATCCATCCAGCGGCATCACGGTGGGCGATGCCAGGCTTGTTGCCGTCTATTCTTGTGCCTGCCCGCCGTTATCCAG
CCTCAACGGAGAGCTCCCCC

Downstream 100 bases:

>100_bases
ATCAACCACGTCACTGCCCGGCGGTTCTGATCGCCGCGCCGGCTTCCGGTCAGGGCAAGACCACCGTCACCGCCGCGCTG
GCCCGTCTGCATCGCAATCA

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MTDSPERDERHLARMQRKKAVIDERIANSPDECGLVLVLTGNGKGKSSSAFGMLARAMGHGMQCGVVQFIKGRNSTGEEL
FFRRFPEQVRFHVMGEGFTWETQDRQRDIAAAEAAWEVSRELLRDPSIGLVVLDELNIALKHGYLDLDQVLSDLQARPPM
QHVIVTGRAAKPEMIEMGDTVTEMGMIKHAFQAGIKAQKGVEL

Sequences:

>Translated_203_residues
MTDSPERDERHLARMQRKKAVIDERIANSPDECGLVLVLTGNGKGKSSSAFGMLARAMGHGMQCGVVQFIKGRNSTGEEL
FFRRFPEQVRFHVMGEGFTWETQDRQRDIAAAEAAWEVSRELLRDPSIGLVVLDELNIALKHGYLDLDQVLSDLQARPPM
QHVIVTGRAAKPEMIEMGDTVTEMGMIKHAFQAGIKAQKGVEL
>Mature_202_residues
TDSPERDERHLARMQRKKAVIDERIANSPDECGLVLVLTGNGKGKSSSAFGMLARAMGHGMQCGVVQFIKGRNSTGEELF
FRRFPEQVRFHVMGEGFTWETQDRQRDIAAAEAAWEVSRELLRDPSIGLVVLDELNIALKHGYLDLDQVLSDLQARPPMQ
HVIVTGRAAKPEMIEMGDTVTEMGMIKHAFQAGIKAQKGVEL

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=46.4285714285714, Blast_Score=190, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22604; Mature: 22473

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSPERDERHLARMQRKKAVIDERIANSPDECGLVLVLTGNGKGKSSSAFGMLARAMGH
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCC
GMQCGVVQFIKGRNSTGEELFFRRFPEQVRFHVMGEGFTWETQDRQRDIAAAEAAWEVSR
CCCHHHHHHHHCCCCCHHHHHHHHCHHHHEEEEECCCCEECCCHHHHHHHHHHHHHHHHH
ELLRDPSIGLVVLDELNIALKHGYLDLDQVLSDLQARPPMQHVIVTGRAAKPEMIEMGDT
HHHCCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHCCH
VTEMGMIKHAFQAGIKAQKGVEL
HHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDSPERDERHLARMQRKKAVIDERIANSPDECGLVLVLTGNGKGKSSSAFGMLARAMGH
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCC
GMQCGVVQFIKGRNSTGEELFFRRFPEQVRFHVMGEGFTWETQDRQRDIAAAEAAWEVSR
CCCHHHHHHHHCCCCCHHHHHHHHCHHHHEEEEECCCCEECCCHHHHHHHHHHHHHHHHH
ELLRDPSIGLVVLDELNIALKHGYLDLDQVLSDLQARPPMQHVIVTGRAAKPEMIEMGDT
HHHCCCCCCEEEEECCCCHHHCCCCCHHHHHHHHHCCCCHHHEEEECCCCCCHHHHHCCH
VTEMGMIKHAFQAGIKAQKGVEL
HHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]