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The map label for this gene is rutD [H]

Identifier: 77457656

GI number: 77457656

Start: 1604928

End: 1605731

Strand: Reverse

Name: rutD [H]

Synonym: Pfl01_1429

Alternate gene names: 77457656

Gene position: 1605731-1604928 (Counterclockwise)

Preceding gene: 77457657

Following gene: 77457655

Centisome position: 24.94

GC content: 62.06

Gene sequence:

>804_bases
ATGGCGTATTTCGAGCATGAAGGTTGCAACCTGCACTACGAGGAATATGGCCACGGCGTTCCGTTGCTGCTGGTTCACGG
TCTGGGCTCCAGCACCCTGGACTGGGAAATGCAGATTCCCGCGCTGGCCGCGCATTACCGGGTGATCGTCCCGGACGTGC
GCGGTCACGGTCGCTCCGACAAGCCCCGCGAGCGCTACAGCATCGCCGGCTTCAGCGCCGACATCGTTGCCCTGATCGAA
CACCTGAAGCTTGGCCCGGTGCACTACGTCGGGCTGTCCATGGGCGGCATGATCGGCTTCCAGTTCGCCGTCGATCACCC
GCGGATGCTCAAGAGCCTGACCATCGTCAACAGCGCGCCCGAGGTCAAGGTGCGCAGCCGCGACGATTACTGGCAGTGGT
TCAAACGCTGGAGCCTGATGCGCCTGCTCAGCCTCGCCACCATCGGCAAGGCCCTTGGCGCCAAGCTGTTCCCCAAACCG
GAGCAGGCCGATTTGCGTCAGAAGATGGCCGAACGCTGGGCAAAAAACGACAAACGTGCTTATCTCGCCAGCTTCGATGC
GATTGTTGGCTGGGGGGTCCAGGAACGACTTTCCCGGGTCACCTGTCCAACCCTCGTCGTCAGCGCCGACCGGGACTACA
CCCCCGTTTCGTTGAAAGAAACCTATGTCAGACTGCTGCCCGATGCGCGGCTGGTGGTGATCGCCGACTCGCGCCATGCC
ACCCCGCTCGATCAGCCCGAACGCTTCAATCAAACGCTGCTGGAGTTCCTCGCCACAGCCGATAATCACCCTCAGGATCA
CTGA

Upstream 100 bases:

>100_bases
CAGCGACGCAAATCCTGATCGAACTGCTGCGCACCTTCGACACCCTGCCGCTGGACGCACCGTTCGCCGCCCCCGAACAA
GCCTGACACGGAGTTCACCG

Downstream 100 bases:

>100_bases
CCCATGCTGAAAAAACTCGCCCTCGCCGCCGGCACCGTGCTGTTCGCTGCCAACCTGATGGCTGCCACGCCGGCAAAAGC
ACCGCACGTGCTGCTGGACA

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MAYFEHEGCNLHYEEYGHGVPLLLVHGLGSSTLDWEMQIPALAAHYRVIVPDVRGHGRSDKPRERYSIAGFSADIVALIE
HLKLGPVHYVGLSMGGMIGFQFAVDHPRMLKSLTIVNSAPEVKVRSRDDYWQWFKRWSLMRLLSLATIGKALGAKLFPKP
EQADLRQKMAERWAKNDKRAYLASFDAIVGWGVQERLSRVTCPTLVVSADRDYTPVSLKETYVRLLPDARLVVIADSRHA
TPLDQPERFNQTLLEFLATADNHPQDH

Sequences:

>Translated_267_residues
MAYFEHEGCNLHYEEYGHGVPLLLVHGLGSSTLDWEMQIPALAAHYRVIVPDVRGHGRSDKPRERYSIAGFSADIVALIE
HLKLGPVHYVGLSMGGMIGFQFAVDHPRMLKSLTIVNSAPEVKVRSRDDYWQWFKRWSLMRLLSLATIGKALGAKLFPKP
EQADLRQKMAERWAKNDKRAYLASFDAIVGWGVQERLSRVTCPTLVVSADRDYTPVSLKETYVRLLPDARLVVIADSRHA
TPLDQPERFNQTLLEFLATADNHPQDH
>Mature_266_residues
AYFEHEGCNLHYEEYGHGVPLLLVHGLGSSTLDWEMQIPALAAHYRVIVPDVRGHGRSDKPRERYSIAGFSADIVALIEH
LKLGPVHYVGLSMGGMIGFQFAVDHPRMLKSLTIVNSAPEVKVRSRDDYWQWFKRWSLMRLLSLATIGKALGAKLFPKPE
QADLRQKMAERWAKNDKRAYLASFDAIVGWGVQERLSRVTCPTLVVSADRDYTPVSLKETYVRLLPDARLVVIADSRHAT
PLDQPERFNQTLLEFLATADNHPQDH

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=309, Percent_Identity=23.6245954692557, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI218777837, Length=280, Percent_Identity=25.7142857142857, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787244, Length=251, Percent_Identity=27.4900398406374, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=280, Percent_Identity=24.2857142857143, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 30270; Mature: 30139

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYFEHEGCNLHYEEYGHGVPLLLVHGLGSSTLDWEMQIPALAAHYRVIVPDVRGHGRSD
CCEEECCCCEEEHHHHCCCCCEEEEECCCCCCCEEEEECCHHHHCEEEEEECCCCCCCCC
KPRERYSIAGFSADIVALIEHLKLGPVHYVGLSMGGMIGFQFAVDHPRMLKSLTIVNSAP
CCHHHEEECCCCHHHHHHHHHHCCCCEEEEHHHHCCCEEEEEECCCHHHHHHHHHCCCCC
EVKVRSRDDYWQWFKRWSLMRLLSLATIGKALGAKLFPKPEQADLRQKMAERWAKNDKRA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHH
YLASFDAIVGWGVQERLSRVTCPTLVVSADRDYTPVSLKETYVRLLPDARLVVIADSRHA
HHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCC
TPLDQPERFNQTLLEFLATADNHPQDH
CCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AYFEHEGCNLHYEEYGHGVPLLLVHGLGSSTLDWEMQIPALAAHYRVIVPDVRGHGRSD
CEEECCCCEEEHHHHCCCCCEEEEECCCCCCCEEEEECCHHHHCEEEEEECCCCCCCCC
KPRERYSIAGFSADIVALIEHLKLGPVHYVGLSMGGMIGFQFAVDHPRMLKSLTIVNSAP
CCHHHEEECCCCHHHHHHHHHHCCCCEEEEHHHHCCCEEEEEECCCHHHHHHHHHCCCCC
EVKVRSRDDYWQWFKRWSLMRLLSLATIGKALGAKLFPKPEQADLRQKMAERWAKNDKRA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHH
YLASFDAIVGWGVQERLSRVTCPTLVVSADRDYTPVSLKETYVRLLPDARLVVIADSRHA
HHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCC
TPLDQPERFNQTLLEFLATADNHPQDH
CCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA