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The map label for this gene is yhjE [H]

Identifier: 77457242

GI number: 77457242

Start: 1178993

End: 1180309

Strand: Reverse

Name: yhjE [H]

Synonym: Pfl01_1015

Alternate gene names: 77457242

Gene position: 1180309-1178993 (Counterclockwise)

Preceding gene: 77457243

Following gene: 77457236

Centisome position: 18.33

GC content: 62.49

Gene sequence:

>1317_bases
ATGACGACCAGTACCGCTTACAGCGACACCACGCCTGCCCAACCGACCAACTCCGCCACCCGCGTGGCCACGGCAAGCTT
CATCGGCACGGCCATCGAGTTCTACGATTTCTATGTCTACGCCACCGCCGCTGCGCTGGTGATCGGGCCGGTGTTTTTCC
CGCAGACTTCCGGCACGGCGCAGATGCTTTCGGCATTTCTTACCTTCGGCATCGCCTTCCTGGCCCGACCGCTGGGCTCG
GCGCTGTTCGGCCATTTCGGCGACCGGATCGGGCGCAAATCGACTTTGGTCGCTTCGCTGCTGCTGATGGGTGTCTGCAC
CACGCTGATCGGCGTGCTGCCGGGCTACGACAGCATCGGGGCCTGGGCGCCGATCCTGCTTTGCGTACTGCGTTTCGGCC
AAGGCCTGGGATTGGGTGGCGAATGGGGCGGTGCAGCGCTGCTGGCGACCGAAAACGCGCCGAAAGGCAAACGGGCGTGG
TTCGGCATGTTCCCGCAACTCGGGCCTTCGATTGGTTTTCTGGCCGCCAACGGTCTGTTCCTGACCCTTGCCATGAGCCT
GAACGACGATCAGTTCCGCAGTTGGGGCTGGCGGATTCCGTTCCTGCTCAGCGCTGTGCTGGTGATGGTCGGGCTGTACG
TGCGCCTCAAGCTGCACGAGACCCCGGTGTTCGCCAACGCCATCGCCCGTCAGGAGCGAGTGAAAGTGCCGCTGGTCGAG
CTGTTCAGCCAATACTGGGTACCGACATTGCTTGGTGCCGCTGCCATGGTGGTGTGCTACGCCCTGTTCTACATCTCGAC
GGTGTTTTCCCTGAGCTACGGCGTATCCACATTGGGCTACAGCCGTGAGACTTTCCTCGGGCTGCTGTGCTTCGCAGTAC
TGTTCATGGCAGCCGCGACGCCGTTGTCGGCGTGGGCAAGCGATCGTTACGGGCGCAAGCCGGTGCTGATCGTCGGCGGT
GTGCTGGCGATTCTTTCCGGGTTTCTGATGGAGCCGCTGCTGACTCAGGGTTCGACCTGGGGCGTGGCCCTGTTCCTGTG
CATCGAGCTGTTTCTGATGGGGGTGACATTCGCCCCAATGGGCGCGCTGCTGCCGGAGCTGTTTCCGACACACGTCCGCT
ATACCGGTGCATCGGCGGCCTACAACCTCGGCGGCATTGTCGGAGCCTCGGCGGCGCCATTCTTTGCGCAGAAACTGGTG
GCGATGGGTGGTTTGAGTTACGTCGGCGGGTATGTGTCTGCGGCCGCGGTGCTCAGCCTGATCGCTGTGCTGTGCCTGAA
GGAAACGCGCAATAACGATTTGAATCAGGTGTCGTAA

Upstream 100 bases:

>100_bases
GTTCCTACCTGAAGCAGCGATCGCGCCTCATCCCACATCCCTGGGTGTTCGACCATAATAATTCGCTCCAACGGAGCTCA
TGACTGTCAGGGATCACCGC

Downstream 100 bases:

>100_bases
ATGCCCTGATCGCTCCCGCCCGATGCGGGAGCGATCAGGTTGCGAGATTACAGCTCTACAACGACAGCCTGAGAAGCACG
GGTCGCCTTGGCACGAGCGG

Product: general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MTTSTAYSDTTPAQPTNSATRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTAQMLSAFLTFGIAFLARPLGS
ALFGHFGDRIGRKSTLVASLLLMGVCTTLIGVLPGYDSIGAWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAW
FGMFPQLGPSIGFLAANGLFLTLAMSLNDDQFRSWGWRIPFLLSAVLVMVGLYVRLKLHETPVFANAIARQERVKVPLVE
LFSQYWVPTLLGAAAMVVCYALFYISTVFSLSYGVSTLGYSRETFLGLLCFAVLFMAAATPLSAWASDRYGRKPVLIVGG
VLAILSGFLMEPLLTQGSTWGVALFLCIELFLMGVTFAPMGALLPELFPTHVRYTGASAAYNLGGIVGASAAPFFAQKLV
AMGGLSYVGGYVSAAAVLSLIAVLCLKETRNNDLNQVS

Sequences:

>Translated_438_residues
MTTSTAYSDTTPAQPTNSATRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTAQMLSAFLTFGIAFLARPLGS
ALFGHFGDRIGRKSTLVASLLLMGVCTTLIGVLPGYDSIGAWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAW
FGMFPQLGPSIGFLAANGLFLTLAMSLNDDQFRSWGWRIPFLLSAVLVMVGLYVRLKLHETPVFANAIARQERVKVPLVE
LFSQYWVPTLLGAAAMVVCYALFYISTVFSLSYGVSTLGYSRETFLGLLCFAVLFMAAATPLSAWASDRYGRKPVLIVGG
VLAILSGFLMEPLLTQGSTWGVALFLCIELFLMGVTFAPMGALLPELFPTHVRYTGASAAYNLGGIVGASAAPFFAQKLV
AMGGLSYVGGYVSAAAVLSLIAVLCLKETRNNDLNQVS
>Mature_437_residues
TTSTAYSDTTPAQPTNSATRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTAQMLSAFLTFGIAFLARPLGSA
LFGHFGDRIGRKSTLVASLLLMGVCTTLIGVLPGYDSIGAWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAWF
GMFPQLGPSIGFLAANGLFLTLAMSLNDDQFRSWGWRIPFLLSAVLVMVGLYVRLKLHETPVFANAIARQERVKVPLVEL
FSQYWVPTLLGAAAMVVCYALFYISTVFSLSYGVSTLGYSRETFLGLLCFAVLFMAAATPLSAWASDRYGRKPVLIVGGV
LAILSGFLMEPLLTQGSTWGVALFLCIELFLMGVTFAPMGALLPELFPTHVRYTGASAAYNLGGIVGASAAPFFAQKLVA
MGGLSYVGGYVSAAAVLSLIAVLCLKETRNNDLNQVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789941, Length=437, Percent_Identity=53.3180778032037, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788292, Length=440, Percent_Identity=38.1818181818182, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1790550, Length=429, Percent_Identity=33.1002331002331, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1788942, Length=433, Percent_Identity=30.4849884526559, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87082404, Length=362, Percent_Identity=26.5193370165746, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082231, Length=246, Percent_Identity=27.2357723577236, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1; PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 46513; Mature: 46382

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSTAYSDTTPAQPTNSATRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QMLSAFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVASLLLMGVCTTLIGVLPGYDSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGFLAANGLF
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCHHHCCCHHHHHHCCEE
LTLAMSLNDDQFRSWGWRIPFLLSAVLVMVGLYVRLKLHETPVFANAIARQERVKVPLVE
EEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCHHHH
LFSQYWVPTLLGAAAMVVCYALFYISTVFSLSYGVSTLGYSRETFLGLLCFAVLFMAAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PLSAWASDRYGRKPVLIVGGVLAILSGFLMEPLLTQGSTWGVALFLCIELFLMGVTFAPM
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GALLPELFPTHVRYTGASAAYNLGGIVGASAAPFFAQKLVAMGGLSYVGGYVSAAAVLSL
HHHHHHHHHHHHEECCCHHHHHCCCHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IAVLCLKETRNNDLNQVS
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTSTAYSDTTPAQPTNSATRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QMLSAFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVASLLLMGVCTTLIGVLPGYDSIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
AWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGFLAANGLF
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCHHHCCCHHHHHHCCEE
LTLAMSLNDDQFRSWGWRIPFLLSAVLVMVGLYVRLKLHETPVFANAIARQERVKVPLVE
EEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCHHHH
LFSQYWVPTLLGAAAMVVCYALFYISTVFSLSYGVSTLGYSRETFLGLLCFAVLFMAAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
PLSAWASDRYGRKPVLIVGGVLAILSGFLMEPLLTQGSTWGVALFLCIELFLMGVTFAPM
HHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GALLPELFPTHVRYTGASAAYNLGGIVGASAAPFFAQKLVAMGGLSYVGGYVSAAAVLSL
HHHHHHHHHHHHEECCCHHHHHCCCHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IAVLCLKETRNNDLNQVS
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]