BacMap

Definition	Pseudomonas fluorescens Pf0-1 chromosome, complete genome.
Accession	NC_007492
Length	6,438,405

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The map label for this gene is fabG [C]

Identifier: 77457130

GI number: 77457130

Start: 1045756

End: 1046667

Strand: Direct

Name: fabG [C]

Synonym: Pfl01_0903

Alternate gene names: 77457130

Gene position: 1045756-1046667 (Clockwise)

Preceding gene: 77457129

Following gene: 77457132

Centisome position: 16.24

GC content: 61.95

Gene sequence:

>912_bases
ATGAATGAGTCTGTGCGTTTCGAAGATAAAGTCGTGATCGTCACCGGAGCCGGTGGTGGCCTGGGACGCGCTCACGCTTT
GCTGTTCGCCAAACAGGGCGCCAAAGTGCTGGTCAACGACCTCGGCGGCTCGACTCAGGGCGAAGGCGCCAACGCTTCGG
CCGCCGACCGCGTGGTGGCGGAAATCCGCGAGGCCGGCGGCATCGCCGAAGCCAACCACGATTCGGTTACCGACGGCGAC
AAACTGGTACAGAACGCCCTCGACGTGTTCGGTCGCGTCGATGTCGTGGTCAACAACGCCGGGATCCTGCGCGACAAGAC
CTTCCATAAAATGGAAGACGCCGACTGGGATCTGGTCTACCGCGTCCACGTCGAAGGCGCCTATAAAGTGACCCGCGCCG
CCTGGCCCCATCTGCGCGAGCAAAATTACGGCCGGGTGATCTTCACCGCCTCGACCTCGGGCATCTACGGCAATTTCGGC
CAGTCCAACTACGGCATGGCCAAACTCGGCCTCTACGGCCTGACCCGCACCCTGGCCATCGAAGGTCGCAAGAACAACAT
CCTGGTCAACGCCATCGCTCCCACCGGCGGCACCCGCATGACCGAAGGCCTGATTCCGCCGCAAGTGTTCGAACAACTCA
AGCCTGAACTGGTCAGCCCGCTGGTGGTGTACCTGGCCAGTGAACAGTGCCAGGAAACCTCGGGCCTGTTCGAAGTCGGC
GGCGGCTGGATGGGCAAGGTGCGCTGGGAGCGCAGCCTGGGCGCCGGCTTCGATCCACGCGTCGGGTTTTCCCCGGAAGA
CGTCGCGGCGCACTGGCAGCAGATCTGTGATTTCGAAGGTGCGGCGCATCCGAAGGACAATATCGAGGCGCTGAAGGAAA
TGATGGGGAATTTGCAGAAGTATTCGTTGTAA

Upstream 100 bases:

>100_bases
TTATCGCGCACCATTCAGCCCCAGCCGTGTTCGTTGTGACCGCACGCTCTGTGCCTGACACTCAGGGACACTGTCCCTCA
GGTCTGCTGGAGTTGCCCCG

Downstream 100 bases:

>100_bases
TACATAAAGAGACGAGCAGGCATGAGTTGCCTGCTCGTTGTTTGCTTTCTATTCTTCGTTTTTAAATCCGGGTTTTCCGT
TGGCAGCGCGCCAAGCCTTG

Product: Short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNESVRFEDKVVIVTGAGGGLGRAHALLFAKQGAKVLVNDLGGSTQGEGANASAADRVVAEIREAGGIAEANHDSVTDGD
KLVQNALDVFGRVDVVVNNAGILRDKTFHKMEDADWDLVYRVHVEGAYKVTRAAWPHLREQNYGRVIFTASTSGIYGNFG
QSNYGMAKLGLYGLTRTLAIEGRKNNILVNAIAPTGGTRMTEGLIPPQVFEQLKPELVSPLVVYLASEQCQETSGLFEVG
GGWMGKVRWERSLGAGFDPRVGFSPEDVAAHWQQICDFEGAAHPKDNIEALKEMMGNLQKYSL

Sequences:

>Translated_303_residues
MNESVRFEDKVVIVTGAGGGLGRAHALLFAKQGAKVLVNDLGGSTQGEGANASAADRVVAEIREAGGIAEANHDSVTDGD
KLVQNALDVFGRVDVVVNNAGILRDKTFHKMEDADWDLVYRVHVEGAYKVTRAAWPHLREQNYGRVIFTASTSGIYGNFG
QSNYGMAKLGLYGLTRTLAIEGRKNNILVNAIAPTGGTRMTEGLIPPQVFEQLKPELVSPLVVYLASEQCQETSGLFEVG
GGWMGKVRWERSLGAGFDPRVGFSPEDVAAHWQQICDFEGAAHPKDNIEALKEMMGNLQKYSL
>Mature_303_residues
MNESVRFEDKVVIVTGAGGGLGRAHALLFAKQGAKVLVNDLGGSTQGEGANASAADRVVAEIREAGGIAEANHDSVTDGD
KLVQNALDVFGRVDVVVNNAGILRDKTFHKMEDADWDLVYRVHVEGAYKVTRAAWPHLREQNYGRVIFTASTSGIYGNFG
QSNYGMAKLGLYGLTRTLAIEGRKNNILVNAIAPTGGTRMTEGLIPPQVFEQLKPELVSPLVVYLASEQCQETSGLFEVG
GGWMGKVRWERSLGAGFDPRVGFSPEDVAAHWQQICDFEGAAHPKDNIEALKEMMGNLQKYSL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4504505, Length=301, Percent_Identity=56.8106312292359, Blast_Score=362, Evalue=1e-100,
Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=32.5842696629214, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=29.2307692307692, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40254992, Length=210, Percent_Identity=31.4285714285714, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI66933014, Length=263, Percent_Identity=28.1368821292776, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=25.1336898395722, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI126723191, Length=197, Percent_Identity=28.4263959390863, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=29.3814432989691, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI10190704, Length=269, Percent_Identity=27.1375464684015, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=32.0158102766798, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082100, Length=197, Percent_Identity=30.4568527918782, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=31.2741312741313, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=29.5546558704453, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790717, Length=214, Percent_Identity=29.9065420560748, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=27.9166666666667, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082160, Length=185, Percent_Identity=30.2702702702703, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789057, Length=215, Percent_Identity=28.3720930232558, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=280, Percent_Identity=51.0714285714286, Blast_Score=312, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.4, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=208, Percent_Identity=36.5384615384615, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=30.7692307692308, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=31.5, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=189, Percent_Identity=31.2169312169312, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=223, Percent_Identity=32.2869955156951, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=222, Percent_Identity=32.8828828828829, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=246, Percent_Identity=28.8617886178862, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=204, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=199, Percent_Identity=31.1557788944724, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=216, Percent_Identity=30.0925925925926, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=195, Percent_Identity=31.2820512820513, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=177, Percent_Identity=30.5084745762712, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=190, Percent_Identity=31.0526315789474, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=32.1782178217822, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=193, Percent_Identity=30.0518134715026, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=202, Percent_Identity=30.1980198019802, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=203, Percent_Identity=30.0492610837438, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=199, Percent_Identity=26.6331658291457, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=243, Percent_Identity=26.3374485596708, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=177, Percent_Identity=28.2485875706215, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=215, Percent_Identity=26.9767441860465, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=30.5, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=247, Percent_Identity=24.6963562753036, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=219, Percent_Identity=26.9406392694064, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=214, Percent_Identity=28.0373831775701, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=25.3846153846154, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=196, Percent_Identity=27.5510204081633, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=291, Percent_Identity=50.8591065292096, Blast_Score=308, Evalue=8e-85,
Organism=Drosophila melanogaster, GI18859837, Length=298, Percent_Identity=49.3288590604027, Blast_Score=303, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=32.5301204819277, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=30.0395256916996, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357041, Length=200, Percent_Identity=31.5, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24640492, Length=192, Percent_Identity=30.2083333333333, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644339, Length=199, Percent_Identity=29.6482412060301, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17737361, Length=203, Percent_Identity=31.5270935960591, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28571526, Length=192, Percent_Identity=29.6875, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357673, Length=242, Percent_Identity=26.0330578512397, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581726, Length=218, Percent_Identity=27.5229357798165, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355319, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 32750; Mature: 32750

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESVRFEDKVVIVTGAGGGLGRAHALLFAKQGAKVLVNDLGGSTQGEGANASAADRVVA
CCCCCEECCEEEEEEECCCCCCHHHHHEEHHCCCEEEEECCCCCCCCCCCCCHHHHHHHH
EIREAGGIAEANHDSVTDGDKLVQNALDVFGRVDVVVNNAGILRDKTFHKMEDADWDLVY
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHCCCCCCEEEE
RVHVEGAYKVTRAAWPHLREQNYGRVIFTASTSGIYGNFGQSNYGMAKLGLYGLTRTLAI
EEEECCCCHHHHHHCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHCEEEEEE
EGRKNNILVNAIAPTGGTRMTEGLIPPQVFEQLKPELVSPLVVYLASEQCQETSGLFEVG
ECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEC
GGWMGKVRWERSLGAGFDPRVGFSPEDVAAHWQQICDFEGAAHPKDNIEALKEMMGNLQK
CCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
YSL
CCC
>Mature Secondary Structure
MNESVRFEDKVVIVTGAGGGLGRAHALLFAKQGAKVLVNDLGGSTQGEGANASAADRVVA
CCCCCEECCEEEEEEECCCCCCHHHHHEEHHCCCEEEEECCCCCCCCCCCCCHHHHHHHH
EIREAGGIAEANHDSVTDGDKLVQNALDVFGRVDVVVNNAGILRDKTFHKMEDADWDLVY
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHCCCCCCEEEE
RVHVEGAYKVTRAAWPHLREQNYGRVIFTASTSGIYGNFGQSNYGMAKLGLYGLTRTLAI
EEEECCCCHHHHHHCCHHHCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHCEEEEEE
EGRKNNILVNAIAPTGGTRMTEGLIPPQVFEQLKPELVSPLVVYLASEQCQETSGLFEVG
ECCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEEC
GGWMGKVRWERSLGAGFDPRVGFSPEDVAAHWQQICDFEGAAHPKDNIEALKEMMGNLQK
CCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
YSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]