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The map label for this gene is murA [H]

Identifier: 77457096

GI number: 77457096

Start: 1014183

End: 1015448

Strand: Direct

Name: murA [H]

Synonym: Pfl01_0869

Alternate gene names: 77457096

Gene position: 1014183-1015448 (Clockwise)

Preceding gene: 77457095

Following gene: 77457097

Centisome position: 15.75

GC content: 61.45

Gene sequence:

>1266_bases
ATGGATAAATTGATTATTACCGGTGGCGCTCGTCTTGATGGCGAGATCCGCATCTCCGGGGCGAAGAACTCCGCCCTGCC
GATCCTGGCCGCCACCCTGCTGTGCGATGGCCCGGTTACCGTCGGCAACCTGCCGCACCTGCATGACATCACCACCATGA
TCGAGCTGTTCGGTCGCATGGGCATCGAGCCTGTGATCGACGAGAAGCTCAGCGTCGAAATCGACCCGCGCACCATCAAG
ACCCTGATCGCCCCGTACGAACTGGTGAAAACCATGCGTGCGTCGATCCTGGTGCTGGGCCCGATGGTTGCGCGTTTCGG
TGAAGCCGAAGTCGCACTGCCTGGCGGTTGCGCCATCGGTTCGCGTCCGGTCGACCTTCACATCCGTGGCCTGGAAGCCA
TGGGCGCAGTCATCGATGTCGAAGGCGGCTACATCAAGGCCAAGGCGCCTGAAGGCGGCCTGCGCGGCGCGCACTTCTTC
TTCGATACCGTCAGTGTGACCGGTACCGAGAACATCATGATGGCTGCCGCTCTGGCCAAGGGCCGCAGCGTGTTGCAGAA
CGCCGCTCGCGAACCTGAAGTGGTCGACCTGGCGAACTTCCTCAACGCCATGGGTGCCAAGGTTTCCGGTGCCGGAACCG
ACACCATCACCATCGACGGCGTCGAGCGTCTGGGCTCGGCCTTCTATAAGGTCATGCCTGACCGTATCGAAACCGGCACC
TACCTGGTGGCCGCTGCGGTTACCGGTGGCCGCGTGAAGGTCAAGGACACCGATCCGACCATCCTCGAAGCCGTTCTGGA
AAAACTCCGTGAAGCCGGTGCAGAAATCACCTGTGGTGAAGACTGGATCGAGCTGAACATGCACGGCAAGCGCCCGAAAG
CGGTCAACGTGCGCACTGCGCCGTATCCGGCGTTCCCGACCGACATGCAGGCGCAGTTCATCTCGCTCAACGCCATTGCC
GAAGGCACCGGTGCCGTGATCGAGACGATCTTCGAAAACCGCTTCATGCACGTGTACGAACTGCACCGCATGGGCGCGCA
CATCCAGGTCGAAGGCAACACCGCCATTGTGACCGGTATCGAAACACTCAAGGGCGCGCCAGTGATGGCAACCGACCTGC
GTGCTTCGGCGAGCCTGGTGATTTCGGCGCTGGTGGCACAGGGCGATACCCTGATCGACCGCATCTACCACATCGACCGT
GGTTACGAGTGCATCGAGGAAAAACTGCAGATGCTGGGCGCCAAGATCCGTCGCGTTCCGGGCTAA

Upstream 100 bases:

>100_bases
CCTTGGATCGCCGATGGCAGCATCCACGCGGTCACTATGAAATTTTTCAGCAGCGCGGCCTGGGCCGAGCGCACCTGAGC
CCTAGGGCGTCGAGATTCTT

Downstream 100 bases:

>100_bases
TCGCTGCATCTGGACACAGGGAAGTGTCCGTTGAATTCGTTTTGATCGGGGGTGGCAACGCCCTCGAAGTATGTCCGGCG
CCGATTGCGACCGGACATGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDKLIITGGARLDGEIRISGAKNSALPILAATLLCDGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIK
TLIAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAVIDVEGGYIKAKAPEGGLRGAHFF
FDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFLNAMGAKVSGAGTDTITIDGVERLGSAFYKVMPDRIETGT
YLVAAAVTGGRVKVKDTDPTILEAVLEKLREAGAEITCGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIA
EGTGAVIETIFENRFMHVYELHRMGAHIQVEGNTAIVTGIETLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDR
GYECIEEKLQMLGAKIRRVPG

Sequences:

>Translated_421_residues
MDKLIITGGARLDGEIRISGAKNSALPILAATLLCDGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIK
TLIAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAVIDVEGGYIKAKAPEGGLRGAHFF
FDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFLNAMGAKVSGAGTDTITIDGVERLGSAFYKVMPDRIETGT
YLVAAAVTGGRVKVKDTDPTILEAVLEKLREAGAEITCGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIA
EGTGAVIETIFENRFMHVYELHRMGAHIQVEGNTAIVTGIETLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDR
GYECIEEKLQMLGAKIRRVPG
>Mature_421_residues
MDKLIITGGARLDGEIRISGAKNSALPILAATLLCDGPVTVGNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIK
TLIAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAVIDVEGGYIKAKAPEGGLRGAHFF
FDTVSVTGTENIMMAAALAKGRSVLQNAAREPEVVDLANFLNAMGAKVSGAGTDTITIDGVERLGSAFYKVMPDRIETGT
YLVAAAVTGGRVKVKDTDPTILEAVLEKLREAGAEITCGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIA
EGTGAVIETIFENRFMHVYELHRMGAHIQVEGNTAIVTGIETLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDR
GYECIEEKLQMLGAKIRRVPG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=61.2826603325416, Blast_Score=530, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44964; Mature: 44964

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLIITGGARLDGEIRISGAKNSALPILAATLLCDGPVTVGNLPHLHDITTMIELFGRM
CCCEEEECCCEECCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GIEPVIDEKLSVEIDPRTIKTLIAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIG
CCCHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
SRPVDLHIRGLEAMGAVIDVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAK
CCCEEEEEECHHHCCEEEEECCCEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHH
GRSVLQNAAREPEVVDLANFLNAMGAKVSGAGTDTITIDGVERLGSAFYKVMPDRIETGT
HHHHHHHHCCCCCHHHHHHHHHHHCCEECCCCCCEEEECCHHHHHHHHHHHCCCHHCCCC
YLVAAAVTGGRVKVKDTDPTILEAVLEKLREAGAEITCGEDWIELNMHGKRPKAVNVRTA
EEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEEEECC
PYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYELHRMGAHIQVEGNTAIVTGI
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEECCCEEEEEEH
ETLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVP
HHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
G
C
>Mature Secondary Structure
MDKLIITGGARLDGEIRISGAKNSALPILAATLLCDGPVTVGNLPHLHDITTMIELFGRM
CCCEEEECCCEECCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GIEPVIDEKLSVEIDPRTIKTLIAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIG
CCCHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
SRPVDLHIRGLEAMGAVIDVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAAALAK
CCCEEEEEECHHHCCEEEEECCCEEEEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHHH
GRSVLQNAAREPEVVDLANFLNAMGAKVSGAGTDTITIDGVERLGSAFYKVMPDRIETGT
HHHHHHHHCCCCCHHHHHHHHHHHCCEECCCCCCEEEECCHHHHHHHHHHHCCCHHCCCC
YLVAAAVTGGRVKVKDTDPTILEAVLEKLREAGAEITCGEDWIELNMHGKRPKAVNVRTA
EEEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCEEEEECC
PYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYELHRMGAHIQVEGNTAIVTGI
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEECCCEEEEEEH
ETLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVP
HHHCCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA