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The map label for this gene is gufA [H]

Identifier: 77457079

GI number: 77457079

Start: 1002530

End: 1003423

Strand: Direct

Name: gufA [H]

Synonym: Pfl01_0852

Alternate gene names: 77457079

Gene position: 1002530-1003423 (Clockwise)

Preceding gene: 77457078

Following gene: 77457090

Centisome position: 15.57

GC content: 61.86

Gene sequence:

>894_bases
ATGGGCACTGAAACACTGGCGATCGGAAGTGGGCGCATGTTTCGTTACGCAATCGGATCGCTGCTGCTGTTGGCGGGTAT
GACTTTGCTGATCGCCCACGGACTGGAATGGCTGAACCTGGAGCCGAGGTTGTCGCGGGCTCTACAGGGCGGGGCGATTT
TCGCCCTCGGCACCGCACTCGGGGCTGTTCCGGTGCTGGTGATTCGCAACATGCCTCAGGCATTGGGGGATACGCTGTTG
GGTTTTGGCGCTGGCGTGATGCTGGCAGCGACCGCGTTTTCGCTGATCGTGCCGGGAATCGCCGCGGCCGAAGGTCTGGG
GTTGAGCCCTTGGGGCGCCAGCGGCCTGATCTGCTTTGGCATCATGCTCGGGGCGTTTGGCCTTTATCTGGTTGATCGCC
GGGTCTCGGGCGCCTCGCCGGAAATGCTCATCGGCACAGTCGAGCATCCGGTGATTCCGCCGCGGATCTGGTTGTTCGTG
TTCGCCATCATTGCCCATAACATCCCGGAAGGCATGGCGGTCGGTGTCTCGGCGGGTGGTGGCATGTCGGACGCAGACAG
TCTGGCCATGGGCATTGCCTTGCAGGATGTGCCGGAAGGGCTGGTGATTGCACTGGTACTGGCAGGTGCCGGGATGTCGC
GGGTCAAGGCATTCTTGATTGGCGCAGCGTCAGGTCTGGTCGAGCCGGTGTTCGCGCTGCTCTGTGCCTGGCTGGTCAGT
CTTGCCGAGTTGTTGCTACCCTTGGGCTTGGCGTTGGCGGCGGGTGCCATGCTGCTGGTGGTGACTCACGAGGTCATCCC
GGAGTCGCGACGCAATGGTCACGAGAAGCTTGCAAGCCTGGGATTGTTGATCGGTTTCTGTCTGATGATGGTGATGGATA
CGGCGTTGGGCTGA

Upstream 100 bases:

>100_bases
CATCAGCGCGTTCTACAACGTGATCAACTGGCCACAAGTCGCTGCGCGTTATCAGGCCGCGCTGGTTTGAGTCTCCTATA
AAAACAATCCAAGGCTGACT

Downstream 100 bases:

>100_bases
GCCGGGAAGAGGAAGTGAGCTCCCTCGCCTGAAACGGTTTCAACCACCTTCGTCGAAATAGTTGTTGATCAGGGTCACCA
GCGCGTCCATGGCTTCCTGT

Product: Zinc transporter ZIP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MGTETLAIGSGRMFRYAIGSLLLLAGMTLLIAHGLEWLNLEPRLSRALQGGAIFALGTALGAVPVLVIRNMPQALGDTLL
GFGAGVMLAATAFSLIVPGIAAAEGLGLSPWGASGLICFGIMLGAFGLYLVDRRVSGASPEMLIGTVEHPVIPPRIWLFV
FAIIAHNIPEGMAVGVSAGGGMSDADSLAMGIALQDVPEGLVIALVLAGAGMSRVKAFLIGAASGLVEPVFALLCAWLVS
LAELLLPLGLALAAGAMLLVVTHEVIPESRRNGHEKLASLGLLIGFCLMMVMDTALG

Sequences:

>Translated_297_residues
MGTETLAIGSGRMFRYAIGSLLLLAGMTLLIAHGLEWLNLEPRLSRALQGGAIFALGTALGAVPVLVIRNMPQALGDTLL
GFGAGVMLAATAFSLIVPGIAAAEGLGLSPWGASGLICFGIMLGAFGLYLVDRRVSGASPEMLIGTVEHPVIPPRIWLFV
FAIIAHNIPEGMAVGVSAGGGMSDADSLAMGIALQDVPEGLVIALVLAGAGMSRVKAFLIGAASGLVEPVFALLCAWLVS
LAELLLPLGLALAAGAMLLVVTHEVIPESRRNGHEKLASLGLLIGFCLMMVMDTALG
>Mature_296_residues
GTETLAIGSGRMFRYAIGSLLLLAGMTLLIAHGLEWLNLEPRLSRALQGGAIFALGTALGAVPVLVIRNMPQALGDTLLG
FGAGVMLAATAFSLIVPGIAAAEGLGLSPWGASGLICFGIMLGAFGLYLVDRRVSGASPEMLIGTVEHPVIPPRIWLFVF
AIIAHNIPEGMAVGVSAGGGMSDADSLAMGIALQDVPEGLVIALVLAGAGMSRVKAFLIGAASGLVEPVFALLCAWLVSL
AELLLPLGLALAAGAMLLVVTHEVIPESRRNGHEKLASLGLLIGFCLMMVMDTALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=324, Percent_Identity=33.9506172839506, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI229577422, Length=150, Percent_Identity=46.6666666666667, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1789419, Length=218, Percent_Identity=33.0275229357798, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507805, Length=309, Percent_Identity=37.8640776699029, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24652846, Length=182, Percent_Identity=41.2087912087912, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 30384; Mature: 30253

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTETLAIGSGRMFRYAIGSLLLLAGMTLLIAHGLEWLNLEPRLSRALQGGAIFALGTAL
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCCHHHHHHHHH
GAVPVLVIRNMPQALGDTLLGFGAGVMLAATAFSLIVPGIAAAEGLGLSPWGASGLICFG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHH
IMLGAFGLYLVDRRVSGASPEMLIGTVEHPVIPPRIWLFVFAIIAHNIPEGMAVGVSAGG
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCC
GMSDADSLAMGIALQDVPEGLVIALVLAGAGMSRVKAFLIGAASGLVEPVFALLCAWLVS
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAELLLPLGLALAAGAMLLVVTHEVIPESRRNGHEKLASLGLLIGFCLMMVMDTALG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GTETLAIGSGRMFRYAIGSLLLLAGMTLLIAHGLEWLNLEPRLSRALQGGAIFALGTAL
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCCHHHHHHHHH
GAVPVLVIRNMPQALGDTLLGFGAGVMLAATAFSLIVPGIAAAEGLGLSPWGASGLICFG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHHHH
IMLGAFGLYLVDRRVSGASPEMLIGTVEHPVIPPRIWLFVFAIIAHNIPEGMAVGVSAGG
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCC
GMSDADSLAMGIALQDVPEGLVIALVLAGAGMSRVKAFLIGAASGLVEPVFALLCAWLVS
CCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAELLLPLGLALAAGAMLLVVTHEVIPESRRNGHEKLASLGLLIGFCLMMVMDTALG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]