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The map label for this gene is mreD [H]

Identifier: 77457067

GI number: 77457067

Start: 988569

End: 989060

Strand: Direct

Name: mreD [H]

Synonym: Pfl01_0840

Alternate gene names: 77457067

Gene position: 988569-989060 (Clockwise)

Preceding gene: 77457066

Following gene: 77457068

Centisome position: 15.35

GC content: 58.13

Gene sequence:

>492_bases
ATGGTCGGGGCTACCGCATCGCGTAACGGCTGGATTGTCTGGCTGACGTTTATTGTCGGCATTCTGCTCAGTGTGTCGCC
ACTGCCCATTTTCATGGAAATCCTGCGCCCGCTGTGGCTGGCCTTGCTCCTGACTTTCTGGGCTTTGTATTTGCCGCATA
CCGTTGGAATGGTTACGGCGTTCTGCCTGGGATTGGCCGAGGACGTGCTGCAGGGTGATCTGCTCGGTCAGAATGCCTTG
ATCCTGACCCTGATCACGTTCCTGGTGTTGTCATTGCAGCAACGCCTGCGAATGTTCCCGATGTGGCAGCAGAGCCTGGT
GGTTCTGGTGATCTTCGGCTTGGCCCAGCTCGTACAACTCTGGCTCAGTGCCTTGACCGGCAACCGTCAGCCGACCCTCG
CACTGGTCCTGCCGGCACTGGTCAGTGCCTTGCTCTGGCCTTGGGTCAGCTTCGCTTTGCGTGGATTGCGTCGGCGCTAC
AAAATCAACTGA

Upstream 100 bases:

>100_bases
CCACACCAGCGGCCAGCAAACCACCGGCGAATCAGCCGGCGGCTCGACCAGCGGCGAAACCGCCAGTCACTGCGCCGGCT
ACCACCGGGAGGCAAGAATA

Downstream 100 bases:

>100_bases
TTCGGTCAGGCATTTGCCCGCACCTCGACAGGGAGATGTCTTGATGAAAAAGCTTTACCTCGCCTCAGGATCGCCGCGTC
GGCGTGAATTGCTCACGCAG

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MVGATASRNGWIVWLTFIVGILLSVSPLPIFMEILRPLWLALLLTFWALYLPHTVGMVTAFCLGLAEDVLQGDLLGQNAL
ILTLITFLVLSLQQRLRMFPMWQQSLVVLVIFGLAQLVQLWLSALTGNRQPTLALVLPALVSALLWPWVSFALRGLRRRY
KIN

Sequences:

>Translated_163_residues
MVGATASRNGWIVWLTFIVGILLSVSPLPIFMEILRPLWLALLLTFWALYLPHTVGMVTAFCLGLAEDVLQGDLLGQNAL
ILTLITFLVLSLQQRLRMFPMWQQSLVVLVIFGLAQLVQLWLSALTGNRQPTLALVLPALVSALLWPWVSFALRGLRRRY
KIN
>Mature_163_residues
MVGATASRNGWIVWLTFIVGILLSVSPLPIFMEILRPLWLALLLTFWALYLPHTVGMVTAFCLGLAEDVLQGDLLGQNAL
ILTLITFLVLSLQQRLRMFPMWQQSLVVLVIFGLAQLVQLWLSALTGNRQPTLALVLPALVSALLWPWVSFALRGLRRRY
KIN

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=161, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18337; Mature: 18337

Theoretical pI: Translated: 11.67; Mature: 11.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGATASRNGWIVWLTFIVGILLSVSPLPIFMEILRPLWLALLLTFWALYLPHTVGMVTA
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCLGLAEDVLQGDLLGQNALILTLITFLVLSLQQRLRMFPMWQQSLVVLVIFGLAQLVQL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSALTGNRQPTLALVLPALVSALLWPWVSFALRGLRRRYKIN
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVGATASRNGWIVWLTFIVGILLSVSPLPIFMEILRPLWLALLLTFWALYLPHTVGMVTA
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCLGLAEDVLQGDLLGQNALILTLITFLVLSLQQRLRMFPMWQQSLVVLVIFGLAQLVQL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLSALTGNRQPTLALVLPALVSALLWPWVSFALRGLRRRYKIN
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]