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The map label for this gene is fruK [H]

Identifier: 77457021

GI number: 77457021

Start: 933662

End: 934603

Strand: Direct

Name: fruK [H]

Synonym: Pfl01_0794

Alternate gene names: 77457021

Gene position: 933662-934603 (Clockwise)

Preceding gene: 77457020

Following gene: 77457022

Centisome position: 14.5

GC content: 64.12

Gene sequence:

>942_bases
ATGGCCAAGATTCTCACCCTGACCCTGAACCCGGCGCTGGATCTCACGGTGCAGTTGTCACGTCTTGAGGCCGGTCAGGT
CAATCGCAGCGACGAGATGCACACCCACGCCGCCGGCAAGGGCGTCAACGTTGCGCAAGTGCTGGCCGACCTCGGTCATC
AACTGACGGTCAGCGGCTTTCTCGGCGAAGACAATCTGCAAGCGTTCGAAACCCTGTTCGCCAAACGCGGTTTCACCGAT
GCGTTTATCCGGGTGCCCGGCGAGACCCGCAGCAACATCAAGGTCGCGGAACAGAACGGACGCATCACCGATATCAACGG
CCCGGGCCCGGTGGTCGGCGTGGTGGCGCAACAGGCGTTGCTGGAGCGTCTGGTGCAGATCGCGCCGGGGCATGACGCGG
TTGTAGTTGCGGGCAGTTTGCCGCGCGGGGTCAGTGCGCAGTGGTTGCGTGAACTGGTCGAGCGCTTGAAGGCGTTGGGC
CTGAAAGTCGCCCTGGACACCAGCGGCGATGCCTTGCGTGCGGCGCTCAAGGCCGGTCCGTGGCTGATCAAACCGAATAC
CGAAGAGCTGGCCGATGCGCTGGGTTGTGAAGTGGTGTCTCACGCGTCTCAGGCTGAAGCGGCCAATCAGCTGCACGCCC
AGGGCATCGAGCATGTGGTGATCTCCCACGGCGCCGAGGGTGTGAACTGGTTCAGCGTCGGCTCGGCGCTGCATGCGACG
CCGCCAAAGGTCAGCGTCGCCAGCACGGTCGGTGCTGGCGATTCGTTGCTGGCCGGCATGCTCCACGGTCTGCTCAGCGC
CGACACGCCGGAACAAACCCTGCGCACGGCCACCGCAATTGCGGCGCAGGCGGTAACCCAGATCGGTTTCGGTATTCACG
ATGCTGCGCAACTGGTGCAGCTCGAACAGGGCGTGCGCGTGCGCCCCCTGACAGAACAATAA

Upstream 100 bases:

>100_bases
GCATCCGCGAACTCAGCCTGACCCAGACTCAAACCCTTGCTCAACAAGCCCTGGCCGTGGGCAGCGCCAACGAAGTGCGC
GCATTAGTGGAGGCCCTGTA

Downstream 100 bases:

>100_bases
GAGGGTTTGTCATGAAGTTAGCCATTGTCACGTCCTGCCCGAACGGCATGGTCACCAGTGTGCTGTGCGCCCGGTTGCTG
GATGCTGCGGCCCAGCGTCA

Product: PfkB

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MAKILTLTLNPALDLTVQLSRLEAGQVNRSDEMHTHAAGKGVNVAQVLADLGHQLTVSGFLGEDNLQAFETLFAKRGFTD
AFIRVPGETRSNIKVAEQNGRITDINGPGPVVGVVAQQALLERLVQIAPGHDAVVVAGSLPRGVSAQWLRELVERLKALG
LKVALDTSGDALRAALKAGPWLIKPNTEELADALGCEVVSHASQAEAANQLHAQGIEHVVISHGAEGVNWFSVGSALHAT
PPKVSVASTVGAGDSLLAGMLHGLLSADTPEQTLRTATAIAAQAVTQIGFGIHDAAQLVQLEQGVRVRPLTEQ

Sequences:

>Translated_313_residues
MAKILTLTLNPALDLTVQLSRLEAGQVNRSDEMHTHAAGKGVNVAQVLADLGHQLTVSGFLGEDNLQAFETLFAKRGFTD
AFIRVPGETRSNIKVAEQNGRITDINGPGPVVGVVAQQALLERLVQIAPGHDAVVVAGSLPRGVSAQWLRELVERLKALG
LKVALDTSGDALRAALKAGPWLIKPNTEELADALGCEVVSHASQAEAANQLHAQGIEHVVISHGAEGVNWFSVGSALHAT
PPKVSVASTVGAGDSLLAGMLHGLLSADTPEQTLRTATAIAAQAVTQIGFGIHDAAQLVQLEQGVRVRPLTEQ
>Mature_312_residues
AKILTLTLNPALDLTVQLSRLEAGQVNRSDEMHTHAAGKGVNVAQVLADLGHQLTVSGFLGEDNLQAFETLFAKRGFTDA
FIRVPGETRSNIKVAEQNGRITDINGPGPVVGVVAQQALLERLVQIAPGHDAVVVAGSLPRGVSAQWLRELVERLKALGL
KVALDTSGDALRAALKAGPWLIKPNTEELADALGCEVVSHASQAEAANQLHAQGIEHVVISHGAEGVNWFSVGSALHATP
PKVSVASTVGAGDSLLAGMLHGLLSADTPEQTLRTATAIAAQAVTQIGFGIHDAAQLVQLEQGVRVRPLTEQ

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=309, Percent_Identity=43.3656957928803, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1788017, Length=304, Percent_Identity=29.6052631578947, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32739; Mature: 32607

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILTLTLNPALDLTVQLSRLEAGQVNRSDEMHTHAAGKGVNVAQVLADLGHQLTVSGF
CCEEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCEEEEEEE
LGEDNLQAFETLFAKRGFTDAFIRVPGETRSNIKVAEQNGRITDINGPGPVVGVVAQQAL
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHH
LERLVQIAPGHDAVVVAGSLPRGVSAQWLRELVERLKALGLKVALDTSGDALRAALKAGP
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCC
WLIKPNTEELADALGCEVVSHASQAEAANQLHAQGIEHVVISHGAEGVNWFSVGSALHAT
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCEECCCCCCCC
PPKVSVASTVGAGDSLLAGMLHGLLSADTPEQTLRTATAIAAQAVTQIGFGIHDAAQLVQ
CCCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LEQGVRVRPLTEQ
HHCCCEECCCCCC
>Mature Secondary Structure 
AKILTLTLNPALDLTVQLSRLEAGQVNRSDEMHTHAAGKGVNVAQVLADLGHQLTVSGF
CEEEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHCCCEEEEEEE
LGEDNLQAFETLFAKRGFTDAFIRVPGETRSNIKVAEQNGRITDINGPGPVVGVVAQQAL
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHH
LERLVQIAPGHDAVVVAGSLPRGVSAQWLRELVERLKALGLKVALDTSGDALRAALKAGP
HHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCC
WLIKPNTEELADALGCEVVSHASQAEAANQLHAQGIEHVVISHGAEGVNWFSVGSALHAT
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCEECCCCCCCC
PPKVSVASTVGAGDSLLAGMLHGLLSADTPEQTLRTATAIAAQAVTQIGFGIHDAAQLVQ
CCCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LEQGVRVRPLTEQ
HHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]