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The map label for this gene is yocR [H]

Identifier: 77456983

GI number: 77456983

Start: 889017

End: 890420

Strand: Direct

Name: yocR [H]

Synonym: Pfl01_0756

Alternate gene names: 77456983

Gene position: 889017-890420 (Clockwise)

Preceding gene: 77456981

Following gene: 77456984

Centisome position: 13.81

GC content: 59.05

Gene sequence:

>1404_bases
ATGTCGACAGACAAGGTTTCTGTCCACGGCAGTTGGGCTAGCCGCTGGGTTTTCATATTCGCCGCGACCGGTTCGGCCGT
GGGATTGGGCAGCATCTGGAAATTCCCCTACATGGTCGGGGTCTACGGTGGCGGCGCCTTCGTGCTTATGTTTCTGGCGT
GTATCGCGCTGATCGGTATCCCGGTGATGCTCGCCGAAACCCTGATCGGCCGCCGTGCCCGTCAGAGCCCGGCGAATGCC
CTGAAGATGCTGGCGCTGGAAGCCGGTCACTCGGGCAAATGGTCGTGGGGTGCGTTCGCCGGGATGATCACGGCGTTGCT
GATCCTGTCTTTCTACAGTGTGGTCGGCGGCTGGTCGCTGGATTACATCATTGATATGGGGCGCGGAGATTTTCAGGGGG
CTACGGCCGATCAGGTCGGGGCCTATTTTGGCAATGTCATCTCCGACCCCTGGCGCCTGACACTTTGGCACACGGTTTTC
ATGCTGTTGTCGGCTGTGGTGATCGCCAAGGGCGTGGTTGCCGGGCTCGAGCGCAGCCTGCGGATCATGATGCCGCTGCT
GTTCGTGATGGTGCTGGTGCTGCTGGGTTACAGCATGACCACCGGGCATTTCATGGAGGGTGTGCACTTCATGTTCGATT
TCCACCCGGAAAAAGTCCTCGACGGCTTGCTGCCGGCCATGGGCCACGCGTTCTTCTCCCTGAGCGTGGGCGTGGGCTCG
ATCATGATCTACGGCGCCTACATGACCAAGGAAGCCTCGCTGTCCGGCACGGTCGTGGGTGTGGCGCTGCTCGATACCTT
CGTTTCGCTGGTGGCCGGTCTGGCCTTGTTTCCAATTGTGTTCGCCGGTGGTTTGAACCCGAGTGAAGGCCCGGGGCTGA
TGTTCGTCAGCCTGCCATTTGCTTTCGGTAACGTGCTTTTCGGCCAGTTGATGGGCGTGGTGTTTTTCGTTTTAGTGGCG
ATTGCCGCCTGGAGCTCAGCGATTTCCTTGCTTGAGCCGATGGTCGCCTATCTGGTCGAGCGGACTAAAATCAGTCGTGC
CTGGGTGACATTCTGGTTGGCGTTCACCTGTTGGTTCGTTGGCCTGGGCACGGTGTTTTCCTTCAATATCTGGAAGGAAG
CCAAATTTTTCGTGAACGATGGCGGGGTGTTCCATCTCTACCAATGGGGTGCGGCCGGTGGCCTGGACTTCTTTGGTGTG
ATCGACTTCTTCACCTCGCGGATCATGTTGCCGCTCGGCGGGCTGTGCTTTGTGCTGTTTGCCGGTTGGGTGATGGGGCG
TGAAGCGGTGCGTGATGAATTGTCGATTCGCAGCCCGGCGCTGTTCGCCCTGTCTCTGTTCTTGATGCGCTATGTGGCGC
CCATCGGCATTCTTGTAGTGTTTGCCGCCCAGCTCTGGAAGTGA

Upstream 100 bases:

>100_bases
GATAAACGGCTGTCGGCTACGGTGATGCTGCGTGCTTGAGCAGGTTGAGTGAATCCCGGACAATGCGGCCTCTTTTTCTA
ACGCTTGGGCGTGATAAACG

Downstream 100 bases:

>100_bases
CGCTTACATGACGACACATATTCAACGATCGGCGCTGCTGCCTTACCCGGCGCAATTTCTCTACGACCTGGTCAATGACG
TGGCGCGTTACCCCGAGTTT

Product: Sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSTDKVSVHGSWASRWVFIFAATGSAVGLGSIWKFPYMVGVYGGGAFVLMFLACIALIGIPVMLAETLIGRRARQSPANA
LKMLALEAGHSGKWSWGAFAGMITALLILSFYSVVGGWSLDYIIDMGRGDFQGATADQVGAYFGNVISDPWRLTLWHTVF
MLLSAVVIAKGVVAGLERSLRIMMPLLFVMVLVLLGYSMTTGHFMEGVHFMFDFHPEKVLDGLLPAMGHAFFSLSVGVGS
IMIYGAYMTKEASLSGTVVGVALLDTFVSLVAGLALFPIVFAGGLNPSEGPGLMFVSLPFAFGNVLFGQLMGVVFFVLVA
IAAWSSAISLLEPMVAYLVERTKISRAWVTFWLAFTCWFVGLGTVFSFNIWKEAKFFVNDGGVFHLYQWGAAGGLDFFGV
IDFFTSRIMLPLGGLCFVLFAGWVMGREAVRDELSIRSPALFALSLFLMRYVAPIGILVVFAAQLWK

Sequences:

>Translated_467_residues
MSTDKVSVHGSWASRWVFIFAATGSAVGLGSIWKFPYMVGVYGGGAFVLMFLACIALIGIPVMLAETLIGRRARQSPANA
LKMLALEAGHSGKWSWGAFAGMITALLILSFYSVVGGWSLDYIIDMGRGDFQGATADQVGAYFGNVISDPWRLTLWHTVF
MLLSAVVIAKGVVAGLERSLRIMMPLLFVMVLVLLGYSMTTGHFMEGVHFMFDFHPEKVLDGLLPAMGHAFFSLSVGVGS
IMIYGAYMTKEASLSGTVVGVALLDTFVSLVAGLALFPIVFAGGLNPSEGPGLMFVSLPFAFGNVLFGQLMGVVFFVLVA
IAAWSSAISLLEPMVAYLVERTKISRAWVTFWLAFTCWFVGLGTVFSFNIWKEAKFFVNDGGVFHLYQWGAAGGLDFFGV
IDFFTSRIMLPLGGLCFVLFAGWVMGREAVRDELSIRSPALFALSLFLMRYVAPIGILVVFAAQLWK
>Mature_466_residues
STDKVSVHGSWASRWVFIFAATGSAVGLGSIWKFPYMVGVYGGGAFVLMFLACIALIGIPVMLAETLIGRRARQSPANAL
KMLALEAGHSGKWSWGAFAGMITALLILSFYSVVGGWSLDYIIDMGRGDFQGATADQVGAYFGNVISDPWRLTLWHTVFM
LLSAVVIAKGVVAGLERSLRIMMPLLFVMVLVLLGYSMTTGHFMEGVHFMFDFHPEKVLDGLLPAMGHAFFSLSVGVGSI
MIYGAYMTKEASLSGTVVGVALLDTFVSLVAGLALFPIVFAGGLNPSEGPGLMFVSLPFAFGNVLFGQLMGVVFFVLVAI
AAWSSAISLLEPMVAYLVERTKISRAWVTFWLAFTCWFVGLGTVFSFNIWKEAKFFVNDGGVFHLYQWGAAGGLDFFGVI
DFFTSRIMLPLGGLCFVLFAGWVMGREAVRDELSIRSPALFALSLFLMRYVAPIGILVVFAAQLWK

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=451, Percent_Identity=24.390243902439, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI194018524, Length=318, Percent_Identity=24.8427672955975, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI58219014, Length=302, Percent_Identity=24.5033112582781, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI188528618, Length=451, Percent_Identity=21.7294900221729, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI33354281, Length=302, Percent_Identity=23.5099337748344, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI171184408, Length=453, Percent_Identity=21.6335540838852, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI171184406, Length=453, Percent_Identity=21.6335540838852, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI171184404, Length=453, Percent_Identity=21.6335540838852, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI51468073, Length=315, Percent_Identity=22.8571428571429, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI11181770, Length=296, Percent_Identity=23.3108108108108, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI12408638, Length=271, Percent_Identity=23.9852398523985, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI92859670, Length=120, Percent_Identity=34.1666666666667, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI21361693, Length=112, Percent_Identity=33.9285714285714, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146584, Length=407, Percent_Identity=21.1302211302211, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17554804, Length=500, Percent_Identity=23.6, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19921936, Length=446, Percent_Identity=23.3183856502242, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639514, Length=529, Percent_Identity=20.4158790170132, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136952, Length=382, Percent_Identity=21.7277486910995, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221329674, Length=529, Percent_Identity=20.4158790170132, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24655079, Length=301, Percent_Identity=22.5913621262458, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639516, Length=304, Percent_Identity=23.0263157894737, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281364394, Length=379, Percent_Identity=21.6358839050132, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28574704, Length=379, Percent_Identity=21.6358839050132, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17136950, Length=379, Percent_Identity=21.6358839050132, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28574702, Length=379, Percent_Identity=21.6358839050132, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582567, Length=415, Percent_Identity=21.6867469879518, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 50688; Mature: 50557

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDKVSVHGSWASRWVFIFAATGSAVGLGSIWKFPYMVGVYGGGAFVLMFLACIALIGI
CCCCCEEECCCHHCCEEEEEEECCCCCCCCHHHHCCHHEEEECCHHHHHHHHHHHHHHHH
PVMLAETLIGRRARQSPANALKMLALEAGHSGKWSWGAFAGMITALLILSFYSVVGGWSL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
DYIIDMGRGDFQGATADQVGAYFGNVISDPWRLTLWHTVFMLLSAVVIAKGVVAGLERSL
HHEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIMMPLLFVMVLVLLGYSMTTGHFMEGVHFMFDFHPEKVLDGLLPAMGHAFFSLSVGVGS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
IMIYGAYMTKEASLSGTVVGVALLDTFVSLVAGLALFPIVFAGGLNPSEGPGLMFVSLPF
HHEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHH
AFGNVLFGQLMGVVFFVLVAIAAWSSAISLLEPMVAYLVERTKISRAWVTFWLAFTCWFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGTVFSFNIWKEAKFFVNDGGVFHLYQWGAAGGLDFFGVIDFFTSRIMLPLGGLCFVLF
HHHHHHEEHHHHCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGWVMGREAVRDELSIRSPALFALSLFLMRYVAPIGILVVFAAQLWK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STDKVSVHGSWASRWVFIFAATGSAVGLGSIWKFPYMVGVYGGGAFVLMFLACIALIGI
CCCCEEECCCHHCCEEEEEEECCCCCCCCHHHHCCHHEEEECCHHHHHHHHHHHHHHHH
PVMLAETLIGRRARQSPANALKMLALEAGHSGKWSWGAFAGMITALLILSFYSVVGGWSL
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
DYIIDMGRGDFQGATADQVGAYFGNVISDPWRLTLWHTVFMLLSAVVIAKGVVAGLERSL
HHEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIMMPLLFVMVLVLLGYSMTTGHFMEGVHFMFDFHPEKVLDGLLPAMGHAFFSLSVGVGS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHH
IMIYGAYMTKEASLSGTVVGVALLDTFVSLVAGLALFPIVFAGGLNPSEGPGLMFVSLPF
HHEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHH
AFGNVLFGQLMGVVFFVLVAIAAWSSAISLLEPMVAYLVERTKISRAWVTFWLAFTCWFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGTVFSFNIWKEAKFFVNDGGVFHLYQWGAAGGLDFFGVIDFFTSRIMLPLGGLCFVLF
HHHHHHEEHHHHCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AGWVMGREAVRDELSIRSPALFALSLFLMRYVAPIGILVVFAAQLWK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]