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The map label for this gene is ureC [H]

Identifier: 77456808

GI number: 77456808

Start: 672541

End: 674241

Strand: Reverse

Name: ureC [H]

Synonym: Pfl01_0580

Alternate gene names: 77456808

Gene position: 674241-672541 (Counterclockwise)

Preceding gene: 77456809

Following gene: 77456807

Centisome position: 10.47

GC content: 64.14

Gene sequence:

>1701_bases
ATGAAGATTTCCAGACAAGCCTACGCCGACATGTTCGGCCCCACCGTCGGCGACAAGGTGCGCCTGGCCGACACCGAGCT
GTGGATCGAGGTCGAACAGGACTTCACCACCTACGGCGAAGAAGTGAAATTCGGCGGCGGCAAAGTGATCCGCGACGGCC
AGGGCCAGAGCCAGTTGCTGGCGGCCGAAGTGGTCGACACCGTCATCACCAACGCGCTGATCATCGACCACTGGGGCATC
GTCAAAGCCGACGTCGGCCTCAAGGACGGACGCATCGCCGCGATCGGCAAGGCCGGCAATCCGGACGTGCAGCCCGGCGT
GACCATCGCCATCGGCGCCAGCAGCGAAGTGATCGCCGGCGAAGGCATGATCCTCACCGCCGGCGGCATCGACACCCACA
TCCACTTCATTTGCCCGCAGCAGATCGAAGAGGCGCTGATGAGCGGCGTCACCACCATGATCGGTGGTGGCACCGGTCCG
GCCACCGGCACCAATGCAACGACCTGCACTTCGGGGCCGTGGCACCTGGCGCGGATGCTCCAGGCCGCCGACGCGTTCCC
GATGAACATCGGCCTCACCGGCAAGGGCAACGCCAGCCTGCCGGAGCCGTTGATCGAACAGGTCAAGGCCGGCGCCATCG
GCCTCAAGCTGCACGAAGACTGGGGCACCACCCCGGCGAGCATCGACAACTGCCTGAGCGTCGCCGACCAGTACGACGTG
CAAGTGGCAATCCATACCGACACCCTCAACGAGTCCGGTTTCGTCGAAACCACCCTCGGCGCGTTCAAGGGCCGGACCAT
CCACACCTATCACACCGAAGGTGCCGGTGGCGGCCACGCGCCGGACATCATCAAGGCCTGCGGTTTCGCCAACGTACTGC
CGAGTTCGACCAACCCGACCCGGCCGTTCACCCGCAACACCATCGACGAACACCTCGACATGCTGATGGTCTGCCACCAC
CTCGACCCGAGCATTGCCGAAGACGTGGCGTTCGCCGAAAGCCGCATCCGCCGCGAAACGATTGCCGCCGAAGACATCCT
CCACGACCTCGGCGCGTTCTCGATGATCAGCTCCGACAGCCAGGCCATGGGCCGCGTCGGCGAAGTCATCACGCGCACCT
GGCAGACCGCCGACAAGATGAAAAAGCAGCGCGGCCCGCTGCCTCAGGACGGTGAAGGCAACGATAACTTCCGCGCCAAA
CGCTACATCGCCAAGTACACCATCAACCCGGCGATCACCCATGGCATCAGCCATGAAGTGGGTTCGGTGGAAGTCGGCAA
GTGGGCCGATCTGGTGCTGTGGCGCCCGGCATTCTTCGGCGTGAAACCGACGCTGATCCTCAAGGGCGGCGCCATCGCCG
CGAGCCTGATGGGCGACGCCAACGCGTCGATCCCGACCCCGCAACCGGTGCACTACCGCCCGATGTTCGCCAGTTACGGC
GGCTCGCTGCACGCCACCAGCCTGACCTTCATCAGTCAGGCGGCGCAGGCGTCGGGATTGCCCGAAGCATTGGGCCTGAA
GAAGAAAATCGCGGTGGTCAAAGGTTGCCGCGACGTGCAGAAAACCGACCTGATCCACAACGACTATCTGCCGAACATCG
ACGTCGACCCGCAGACCTATCAGGTCAAGGCCGATGGCGTGCTGCTCTGGTGTGAACCGGCCGAAACCCTGCCGATGGCG
CAGCGTTACTTCCTGTTCTGA

Upstream 100 bases:

>100_bases
CCCACCGCGATCAGTCCCCTCTCCCTCCGGGCGGTCCGACGTTTCGGGAGGGTCAGGGAGACGCTCGATGGCTCACCGCT
ATTTTCCTGAAGGACGCTAG

Downstream 100 bases:

>100_bases
CAACCGACAAACGCAAAAAAGGCCCCGAGCACCTGCCTGACGCACGGTCTCGGGGCCTTTTTCGTGATGCTGGAAAACCA
CTGGGCAATGGGTCGTGTAT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha 2 [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MKISRQAYADMFGPTVGDKVRLADTELWIEVEQDFTTYGEEVKFGGGKVIRDGQGQSQLLAAEVVDTVITNALIIDHWGI
VKADVGLKDGRIAAIGKAGNPDVQPGVTIAIGASSEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGP
ATGTNATTCTSGPWHLARMLQAADAFPMNIGLTGKGNASLPEPLIEQVKAGAIGLKLHEDWGTTPASIDNCLSVADQYDV
QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKKQRGPLPQDGEGNDNFRAK
RYIAKYTINPAITHGISHEVGSVEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASYG
GSLHATSLTFISQAAQASGLPEALGLKKKIAVVKGCRDVQKTDLIHNDYLPNIDVDPQTYQVKADGVLLWCEPAETLPMA
QRYFLF

Sequences:

>Translated_566_residues
MKISRQAYADMFGPTVGDKVRLADTELWIEVEQDFTTYGEEVKFGGGKVIRDGQGQSQLLAAEVVDTVITNALIIDHWGI
VKADVGLKDGRIAAIGKAGNPDVQPGVTIAIGASSEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGP
ATGTNATTCTSGPWHLARMLQAADAFPMNIGLTGKGNASLPEPLIEQVKAGAIGLKLHEDWGTTPASIDNCLSVADQYDV
QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKKQRGPLPQDGEGNDNFRAK
RYIAKYTINPAITHGISHEVGSVEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASYG
GSLHATSLTFISQAAQASGLPEALGLKKKIAVVKGCRDVQKTDLIHNDYLPNIDVDPQTYQVKADGVLLWCEPAETLPMA
QRYFLF
>Mature_566_residues
MKISRQAYADMFGPTVGDKVRLADTELWIEVEQDFTTYGEEVKFGGGKVIRDGQGQSQLLAAEVVDTVITNALIIDHWGI
VKADVGLKDGRIAAIGKAGNPDVQPGVTIAIGASSEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGP
ATGTNATTCTSGPWHLARMLQAADAFPMNIGLTGKGNASLPEPLIEQVKAGAIGLKLHEDWGTTPASIDNCLSVADQYDV
QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKKQRGPLPQDGEGNDNFRAK
RYIAKYTINPAITHGISHEVGSVEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASYG
GSLHATSLTFISQAAQASGLPEALGLKKKIAVVKGCRDVQKTDLIHNDYLPNIDVDPQTYQVKADGVLLWCEPAETLPMA
QRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60532; Mature: 60532

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISRQAYADMFGPTVGDKVRLADTELWIEVEQDFTTYGEEVKFGGGKVIRDGQGQSQLL
CCCCHHHHHHHHCCCCCCEEEEECCEEEEEECCCHHCCCCEEEECCCEEEECCCCCHHHH
AAEVVDTVITNALIIDHWGIVKADVGLKDGRIAAIGKAGNPDVQPGVTIAIGASSEVIAG
HHHHHHHHHHHEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCEEEC
EGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTCTSGPWHLARML
CCEEEEECCCCCEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
QAADAFPMNIGLTGKGNASLPEPLIEQVKAGAIGLKLHEDWGTTPASIDNCLSVADQYDV
HHHCCCCEEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEE
QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPT
EEEEEECCCCCCCCEEHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCHHCCCCCCCCC
RPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDS
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QAMGRVGEVITRTWQTADKMKKQRGPLPQDGEGNDNFRAKRYIAKYTINPAITHGISHEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEECCHHHHCCCCCCC
GSVEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASYG
CCEECCCCCEEEEECHHHHCCCCEEEEECCCEEEEHHCCCCCCCCCCCCCEECCHHHHCC
GSLHATSLTFISQAAQASGLPEALGLKKKIAVVKGCRDVQKTDLIHNDYLPNIDVDPQTY
CCEEHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCEE
QVKADGVLLWCEPAETLPMAQRYFLF
EEEECCEEEEECCCCCCCHHHHHHCC
>Mature Secondary Structure
MKISRQAYADMFGPTVGDKVRLADTELWIEVEQDFTTYGEEVKFGGGKVIRDGQGQSQLL
CCCCHHHHHHHHCCCCCCEEEEECCEEEEEECCCHHCCCCEEEECCCEEEECCCCCHHHH
AAEVVDTVITNALIIDHWGIVKADVGLKDGRIAAIGKAGNPDVQPGVTIAIGASSEVIAG
HHHHHHHHHHHEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCEEEC
EGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTCTSGPWHLARML
CCEEEEECCCCCEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
QAADAFPMNIGLTGKGNASLPEPLIEQVKAGAIGLKLHEDWGTTPASIDNCLSVADQYDV
HHHCCCCEEEEECCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCEE
QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPT
EEEEEECCCCCCCCEEHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCHHCCCCCCCCC
RPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDS
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QAMGRVGEVITRTWQTADKMKKQRGPLPQDGEGNDNFRAKRYIAKYTINPAITHGISHEV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEECCHHHHCCCCCCC
GSVEVGKWADLVLWRPAFFGVKPTLILKGGAIAASLMGDANASIPTPQPVHYRPMFASYG
CCEECCCCCEEEEECHHHHCCCCEEEEECCCEEEEHHCCCCCCCCCCCCCEECCHHHHCC
GSLHATSLTFISQAAQASGLPEALGLKKKIAVVKGCRDVQKTDLIHNDYLPNIDVDPQTY
CCEEHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCEE
QVKADGVLLWCEPAETLPMAQRYFLF
EEEECCEEEEECCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA