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The map label for this gene is hicA [H]

Identifier: 77456532

GI number: 77456532

Start: 351918

End: 352109

Strand: Direct

Name: hicA [H]

Synonym: Pfl01_0304

Alternate gene names: 77456532

Gene position: 351918-352109 (Clockwise)

Preceding gene: 77456530

Following gene: 77456533

Centisome position: 5.47

GC content: 51.04

Gene sequence:

>192_bases
GTGATGCACATGAAGTACAGCGAGTTTCGGCGATGGTTGAAAGCCCAAGGCGTTGAGTTCCAAACCGGCAAGGGCAGTCA
CTTCAAGGTTTCCTTGAATGGCAAATCAACTGTCTTTCCCGACCACGGAGCCAAGGAGATGGGCGAAGGGTTGAGAAAAT
CGATAGTCAAACAGCTGGGCCTCAAGGATTGA

Upstream 100 bases:

>100_bases
CAGGTGGTGGCGGAGACTAGCGATGTTCCAGATGTGTGGTGCAACAGTTATGTTGCATGCGTAACAGATATGTTGCACAT
TCGCTCTACCGAAACAGCGA

Downstream 100 bases:

>100_bases
GGCCCAGCTGTACCCCTTATGAGAGGAAGCGTGATGTTCGAATATGCGTTGGAAGTCCACGAAGAGCCGGGCAGTGTCTG
GTTGTCCTGCGCAGAAATTC

Product: hypothetical protein

Products: NA

Alternate protein names: Endoribonuclease HicA; Toxin HicA [H]

Number of amino acids: Translated: 63; Mature: 63

Protein sequence:

>63_residues
MMHMKYSEFRRWLKAQGVEFQTGKGSHFKVSLNGKSTVFPDHGAKEMGEGLRKSIVKQLGLKD

Sequences:

>Translated_63_residues
MMHMKYSEFRRWLKAQGVEFQTGKGSHFKVSLNGKSTVFPDHGAKEMGEGLRKSIVKQLGLKD
>Mature_63_residues
MMHMKYSEFRRWLKAQGVEFQTGKGSHFKVSLNGKSTVFPDHGAKEMGEGLRKSIVKQLGLKD

Specific function: Part of a toxin-antitoxin (TA) module. A probable translation-independent mRNA interferase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HicA mRNA interferase family [H]

Homologues:

Organism=Escherichia coli, GI87081911, Length=58, Percent_Identity=51.7241379310345, Blast_Score=64, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015146
- InterPro:   IPR012933 [H]

Pfam domain/function: PF07927 YcfA [H]

EC number: NA

Molecular weight: Translated: 7168; Mature: 7168

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHMKYSEFRRWLKAQGVEFQTGKGSHFKVSLNGKSTVFPDHGAKEMGEGLRKSIVKQLG
CCCCCHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
LKD
CCC
>Mature Secondary Structure
MMHMKYSEFRRWLKAQGVEFQTGKGSHFKVSLNGKSTVFPDHGAKEMGEGLRKSIVKQLG
CCCCCHHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
LKD
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA