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The map label for this gene is ompR [H]

Identifier: 77456488

GI number: 77456488

Start: 307575

End: 308315

Strand: Direct

Name: ompR [H]

Synonym: Pfl01_0260

Alternate gene names: 77456488

Gene position: 307575-308315 (Clockwise)

Preceding gene: 77456480

Following gene: 77456489

Centisome position: 4.78

GC content: 62.35

Gene sequence:

>741_bases
ATGAGCAGCACTGCACAAACTGCTGAAGGCGAAAAAATTCTCATCGTTGACGACGATCCGGGGCTGAGCAGCCTGCTGGA
ACGATTTTTCGTCAGCAAGGGCTACCGTGCCCGCGCCGTACCGAATACCGAGCAGATGGATCGTCTGCTGTCGCGTGAAG
TGTTCAACCTGGTCGTCCTCGACCTGATGCTGCCGGGCGAAGACGGCCTGACCGCTTGCCGCCGCCTGCGTGGCGCGAAC
AATCAGATTCCGATCATCATGCTCACTGCCAAGGGTGACGAGCTGAGCCGTATCAAGGGCCTGGAACTGGGCGCCGACGA
CTACCTGGCCAAGCCGTTCAACCCGGACGAGCTGATGGCTCGCGTCAAAGCCGTGCTGCGCCGTCAGGCCGCGCCGGTGC
CGGGCGCGCCGGGCAGTGAAGAAGAAAACGTCACGTTCGGCGACTACGTGCTGTCCCTGGCCACCCGCGAACTCAAACGC
GGCGACGAAGTGCACATGCTCACCACCGGCGAGTTTGCGGTACTCAAGGCCCTGGTGATGAACGCCCGTCAGCCGCTGAC
CCGCGACAAGCTGATGAACCTGGCCCGTGGCCGTGAGTGGGATGCCCTGGAGCGTTCCATCGACGTGCAGATTTCCCGTC
TGCGCCGGATGATCGAACCCGATCCTTCCAAGCCGCGCTACATCCAGACTGTCTGGGGTGTCGGCTACGTGTTCGTGCCG
GATGGCAACTCCACCAAGTGA

Upstream 100 bases:

>100_bases
CCCGGTTTTCTGGCAGTGAAGGAAAAATCTGCTAACAATGCACACGGTGCGTATAACGGCAGCTACGCCATAATGCGCGC
CGAGCTAAAAGGAGTATCCA

Downstream 100 bases:

>100_bases
TGGGTGATTTGTAGGAGCGGGTCTGCGGGAAACGGTCGGAAACGCCGTCCGCGCAGACTCGCAATCCGCAATATGCGAGC
ATTGCTCGCTCCTGCAAGTG

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSSTAQTAEGEKILIVDDDPGLSSLLERFFVSKGYRARAVPNTEQMDRLLSREVFNLVVLDLMLPGEDGLTACRRLRGAN
NQIPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMARVKAVLRRQAAPVPGAPGSEEENVTFGDYVLSLATRELKR
GDEVHMLTTGEFAVLKALVMNARQPLTRDKLMNLARGREWDALERSIDVQISRLRRMIEPDPSKPRYIQTVWGVGYVFVP
DGNSTK

Sequences:

>Translated_246_residues
MSSTAQTAEGEKILIVDDDPGLSSLLERFFVSKGYRARAVPNTEQMDRLLSREVFNLVVLDLMLPGEDGLTACRRLRGAN
NQIPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMARVKAVLRRQAAPVPGAPGSEEENVTFGDYVLSLATRELKR
GDEVHMLTTGEFAVLKALVMNARQPLTRDKLMNLARGREWDALERSIDVQISRLRRMIEPDPSKPRYIQTVWGVGYVFVP
DGNSTK
>Mature_245_residues
SSTAQTAEGEKILIVDDDPGLSSLLERFFVSKGYRARAVPNTEQMDRLLSREVFNLVVLDLMLPGEDGLTACRRLRGANN
QIPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMARVKAVLRRQAAPVPGAPGSEEENVTFGDYVLSLATRELKRG
DEVHMLTTGEFAVLKALVMNARQPLTRDKLMNLARGREWDALERSIDVQISRLRRMIEPDPSKPRYIQTVWGVGYVFVPD
GNSTK

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=67.0886075949367, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=36.7965367965368, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=36.9098712446352, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.8936170212766, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=32.7510917030568, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=36.0515021459227, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.8965517241379, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.7826086956522, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=36.3247863247863, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=31.6017316017316, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=31.3304721030043, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=32.0175438596491, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=31.0043668122271, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=30.2521008403361, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=29.7297297297297, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27428; Mature: 27297

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTAQTAEGEKILIVDDDPGLSSLLERFFVSKGYRARAVPNTEQMDRLLSREVFNLVVL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DLMLPGEDGLTACRRLRGANNQIPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMA
HHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHCCCCCCCCHHCCCCCCHHHHHH
RVKAVLRRQAAPVPGAPGSEEENVTFGDYVLSLATRELKRGDEVHMLTTGEFAVLKALVM
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
NARQPLTRDKLMNLARGREWDALERSIDVQISRLRRMIEPDPSKPRYIQTVWGVGYVFVP
HCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEEC
DGNSTK
CCCCCC
>Mature Secondary Structure 
SSTAQTAEGEKILIVDDDPGLSSLLERFFVSKGYRARAVPNTEQMDRLLSREVFNLVVL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DLMLPGEDGLTACRRLRGANNQIPIIMLTAKGDELSRIKGLELGADDYLAKPFNPDELMA
HHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHCCCCCCCCHHCCCCCCHHHHHH
RVKAVLRRQAAPVPGAPGSEEENVTFGDYVLSLATRELKRGDEVHMLTTGEFAVLKALVM
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
NARQPLTRDKLMNLARGREWDALERSIDVQISRLRRMIEPDPSKPRYIQTVWGVGYVFVP
HCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEEC
DGNSTK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]