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The map label for this gene is tauD [H]

Identifier: 77456481

GI number: 77456481

Start: 298990

End: 299832

Strand: Reverse

Name: tauD [H]

Synonym: Pfl01_0253

Alternate gene names: 77456481

Gene position: 299832-298990 (Counterclockwise)

Preceding gene: 77456482

Following gene: 77456477

Centisome position: 4.66

GC content: 62.51

Gene sequence:

>843_bases
ATGAGCAGCCTGAACATCACCCCGTTAAGCTCGGCCCTCGGCGCACAGATCAGCGGCGTCGACATCAGCCAGCCGCTGAA
CCAGGAACAGCGCGACGCCATCGAGCAGGCGCTGCTCAAGTTTCAAGTGCTGTTCTTTCGCAATCAGCCGATCGAACCTT
CGCAACAGGCGCGCTTCGCCCACTATTTCGGCGACTTACACATTCACCCGATCTACCCGAACGTGCCGGAACAACCGGAA
GTGCTGATCCTCGACACCGCCGTCACCGACGTGCGCGACAACGCGATCTGGCACACCGACGTGACCTTCCTGCCGACCCC
GGCCATGGGTGCGGTGCTCAGCGCCAAGCTGTTGCCGGAGTTTGGTGGCGACACGTTGTGGGCCAGCGGAATTGCTGCGT
ATGAAGCGCTCTCGGCGCCGATGAAAGCGCTGCTCGAAGGGCTGACCGCGACTCACGACTTCACCCGCTCGTTTCCGCTG
GAGCGCTATGGCAACACGCCGCAGGCACTGGCGCAGTGGGAAGAGGCGCGGCGCAAGAATCCACCGCTCTCGCATCCGGT
GATTCGCACGCACCCGGTGAGCGGACGGCGTTCGCTGTTCGTCAACGAAGGGTTCACGTCGAAGATCAATGAGCTGTCGG
AGACCGAGAGCGAAGCGGTGTTGAAGTTCTTGTTCGCGCATGCGACGCGGCCGGAGTTCACCATTCGCTGGCGCTGGCAG
AAGGACGACATTGCGTTCTGGGACAACCGCGTGACGCAACATTACGCGGTGGATGACTACCGGCCGGCGCGGCGGGTGAT
GCAGCGGGCTACGGTGTTGGGGGATGTGCCGTTTTTTCGCTGA

Upstream 100 bases:

>100_bases
CCTGCAACGCAAACTGGTGCCGTGGCACGGCCAGGCCCACTGATTTTTCAGCACTGACTACCCCGACAGTTTCGGGGCCC
CGGAATTGAAGAGAACCACC

Downstream 100 bases:

>100_bases
GCCTTTAACGCCAGAGCAAAATCAAGAGCCCCCCTCACCCTAACCCTCTCCCGGAGGGAGAGGGGACTGACCGAGGTGTT
TTGTCGCTATACACCGACCT

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSSLNITPLSSALGAQISGVDISQPLNQEQRDAIEQALLKFQVLFFRNQPIEPSQQARFAHYFGDLHIHPIYPNVPEQPE
VLILDTAVTDVRDNAIWHTDVTFLPTPAMGAVLSAKLLPEFGGDTLWASGIAAYEALSAPMKALLEGLTATHDFTRSFPL
ERYGNTPQALAQWEEARRKNPPLSHPVIRTHPVSGRRSLFVNEGFTSKINELSETESEAVLKFLFAHATRPEFTIRWRWQ
KDDIAFWDNRVTQHYAVDDYRPARRVMQRATVLGDVPFFR

Sequences:

>Translated_280_residues
MSSLNITPLSSALGAQISGVDISQPLNQEQRDAIEQALLKFQVLFFRNQPIEPSQQARFAHYFGDLHIHPIYPNVPEQPE
VLILDTAVTDVRDNAIWHTDVTFLPTPAMGAVLSAKLLPEFGGDTLWASGIAAYEALSAPMKALLEGLTATHDFTRSFPL
ERYGNTPQALAQWEEARRKNPPLSHPVIRTHPVSGRRSLFVNEGFTSKINELSETESEAVLKFLFAHATRPEFTIRWRWQ
KDDIAFWDNRVTQHYAVDDYRPARRVMQRATVLGDVPFFR
>Mature_279_residues
SSLNITPLSSALGAQISGVDISQPLNQEQRDAIEQALLKFQVLFFRNQPIEPSQQARFAHYFGDLHIHPIYPNVPEQPEV
LILDTAVTDVRDNAIWHTDVTFLPTPAMGAVLSAKLLPEFGGDTLWASGIAAYEALSAPMKALLEGLTATHDFTRSFPLE
RYGNTPQALAQWEEARRKNPPLSHPVIRTHPVSGRRSLFVNEGFTSKINELSETESEAVLKFLFAHATRPEFTIRWRWQK
DDIAFWDNRVTQHYAVDDYRPARRVMQRATVLGDVPFFR

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=277, Percent_Identity=59.2057761732852, Blast_Score=348, Evalue=3e-97,
Organism=Saccharomyces cerevisiae, GI6322971, Length=293, Percent_Identity=29.0102389078498, Blast_Score=122, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 31720; Mature: 31589

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLNITPLSSALGAQISGVDISQPLNQEQRDAIEQALLKFQVLFFRNQPIEPSQQARFA
CCCCCCCCCHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
HYFGDLHIHPIYPNVPEQPEVLILDTAVTDVRDNAIWHTDVTFLPTPAMGAVLSAKLLPE
HHHCCEEEEECCCCCCCCCCEEEEECHHHHHCCCCEEECCCEEECCCHHHHHHHHHHHHH
FGGDTLWASGIAAYEALSAPMKALLEGLTATHDFTRSFPLERYGNTPQALAQWEEARRKN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCC
PPLSHPVIRTHPVSGRRSLFVNEGFTSKINELSETESEAVLKFLFAHATRPEFTIRWRWQ
CCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
KDDIAFWDNRVTQHYAVDDYRPARRVMQRATVLGDVPFFR
CCCCHHHCCCCHHEECCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSLNITPLSSALGAQISGVDISQPLNQEQRDAIEQALLKFQVLFFRNQPIEPSQQARFA
CCCCCCCCHHHHCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
HYFGDLHIHPIYPNVPEQPEVLILDTAVTDVRDNAIWHTDVTFLPTPAMGAVLSAKLLPE
HHHCCEEEEECCCCCCCCCCEEEEECHHHHHCCCCEEECCCEEECCCHHHHHHHHHHHHH
FGGDTLWASGIAAYEALSAPMKALLEGLTATHDFTRSFPLERYGNTPQALAQWEEARRKN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCC
PPLSHPVIRTHPVSGRRSLFVNEGFTSKINELSETESEAVLKFLFAHATRPEFTIRWRWQ
CCCCCCCEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
KDDIAFWDNRVTQHYAVDDYRPARRVMQRATVLGDVPFFR
CCCCHHHCCCCHHEECCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]