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The map label for this gene is tauC [H]

Identifier: 77456482

GI number: 77456482

Start: 299890

End: 300729

Strand: Reverse

Name: tauC [H]

Synonym: Pfl01_0254

Alternate gene names: 77456482

Gene position: 300729-299890 (Counterclockwise)

Preceding gene: 77456483

Following gene: 77456481

Centisome position: 4.67

GC content: 64.29

Gene sequence:

>840_bases
ATGAGCAGTTACGACGTTTCCGCTACCGCCGTGAAACCCGCCGCCACGTCGGTGGTGATTCCCGTGCGCCGCAGCCTCAG
CACCCGCTGGATCAGCCTGCTGACCCTGTTCGCATTGTTGGTGATCTGGTGGGCGGTGACGGCCAGTGGCCTGATCGAGC
CGCTGTTCCTGCCGCCACCGTCCGCCGTGCTGCAAAAAGGCTGGTTGCTGGCGACCACGGGTTATATGGATTCGACGTTG
TGGCAGCACTTGGGCGCGAGCCTGAGCCGCATCGGTCTGGGCCTGGGTTTTGCGATTTTGACCGCAGTGCCGGTGGGCAT
TGCCATCGGCGCCAACCGCATCGCCCGTGGCGTGCTGGATCCGCTGATCGAGTTCTACCGGCCGATTCCGCCACTGGCTT
ATCTGCCGCTGATCGTGATCTGGTGCGGCATCGGTGAGTTGTCGAAAGTGCTGCTGATCTATCTGGCGATTTTCGCTCCG
ATCGCGATTGCCACCGCCACCGGTGTGCGCACCGTCGACCCGGCCAAATTGCGCGCCGCACAGTCGCTGGGCGCCACTCG
CGCACAACTGATCCGCCATGTGATTTTGCCAAGCGCCCTGCCGGACATTCTGACCGGTGTGCGCATTGGCCTGGGTGTGG
GTTGGTCGACGCTGGTCGCCGCCGAACTGATCGCGGCCACCAGCGGCCTGGGCTTCATGGTGCAGTCGGCTGCGCAGTTC
CTGGTCACCGATGTGGTGGTGCTGGGGATTCTGGTCATCGCCCTGATCGCCTTCGCTATGGAGATGGGCCTGCGCGCCCT
GCAACGCAAACTGGTGCCGTGGCACGGCCAGGCCCACTGA

Upstream 100 bases:

>100_bases
CGCGGGCGATCAAGTCCGATCCGCGCTTCATCGAAACCCGCGAGCACGTGCTGGCCAAAGTGTTCTCGCAACGCAGCGCC
GTTCAGCGGCAGGAGCGCGC

Downstream 100 bases:

>100_bases
TTTTTCAGCACTGACTACCCCGACAGTTTCGGGGCCCCGGAATTGAAGAGAACCACCATGAGCAGCCTGAACATCACCCC
GTTAAGCTCGGCCCTCGGCG

Product: binding-protein dependent transport system inner membrane protein

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSSYDVSATAVKPAATSVVIPVRRSLSTRWISLLTLFALLVIWWAVTASGLIEPLFLPPPSAVLQKGWLLATTGYMDSTL
WQHLGASLSRIGLGLGFAILTAVPVGIAIGANRIARGVLDPLIEFYRPIPPLAYLPLIVIWCGIGELSKVLLIYLAIFAP
IAIATATGVRTVDPAKLRAAQSLGATRAQLIRHVILPSALPDILTGVRIGLGVGWSTLVAAELIAATSGLGFMVQSAAQF
LVTDVVVLGILVIALIAFAMEMGLRALQRKLVPWHGQAH

Sequences:

>Translated_279_residues
MSSYDVSATAVKPAATSVVIPVRRSLSTRWISLLTLFALLVIWWAVTASGLIEPLFLPPPSAVLQKGWLLATTGYMDSTL
WQHLGASLSRIGLGLGFAILTAVPVGIAIGANRIARGVLDPLIEFYRPIPPLAYLPLIVIWCGIGELSKVLLIYLAIFAP
IAIATATGVRTVDPAKLRAAQSLGATRAQLIRHVILPSALPDILTGVRIGLGVGWSTLVAAELIAATSGLGFMVQSAAQF
LVTDVVVLGILVIALIAFAMEMGLRALQRKLVPWHGQAH
>Mature_278_residues
SSYDVSATAVKPAATSVVIPVRRSLSTRWISLLTLFALLVIWWAVTASGLIEPLFLPPPSAVLQKGWLLATTGYMDSTLW
QHLGASLSRIGLGLGFAILTAVPVGIAIGANRIARGVLDPLIEFYRPIPPLAYLPLIVIWCGIGELSKVLLIYLAIFAPI
AIATATGVRTVDPAKLRAAQSLGATRAQLIRHVILPSALPDILTGVRIGLGVGWSTLVAAELIAATSGLGFMVQSAAQFL
VTDVVVLGILVIALIAFAMEMGLRALQRKLVPWHGQAH

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=264, Percent_Identity=63.6363636363636, Blast_Score=306, Evalue=1e-84,
Organism=Escherichia coli, GI87081802, Length=238, Percent_Identity=36.1344537815126, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789033, Length=174, Percent_Identity=29.8850574712644, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29561; Mature: 29430

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSYDVSATAVKPAATSVVIPVRRSLSTRWISLLTLFALLVIWWAVTASGLIEPLFLPPP
CCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SAVLQKGWLLATTGYMDSTLWQHLGASLSRIGLGLGFAILTAVPVGIAIGANRIARGVLD
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLIEFYRPIPPLAYLPLIVIWCGIGELSKVLLIYLAIFAPIAIATATGVRTVDPAKLRAA
HHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QSLGATRAQLIRHVILPSALPDILTGVRIGLGVGWSTLVAAELIAATSGLGFMVQSAAQF
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
LVTDVVVLGILVIALIAFAMEMGLRALQRKLVPWHGQAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SSYDVSATAVKPAATSVVIPVRRSLSTRWISLLTLFALLVIWWAVTASGLIEPLFLPPP
CCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SAVLQKGWLLATTGYMDSTLWQHLGASLSRIGLGLGFAILTAVPVGIAIGANRIARGVLD
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLIEFYRPIPPLAYLPLIVIWCGIGELSKVLLIYLAIFAPIAIATATGVRTVDPAKLRAA
HHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
QSLGATRAQLIRHVILPSALPDILTGVRIGLGVGWSTLVAAELIAATSGLGFMVQSAAQF
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
LVTDVVVLGILVIALIAFAMEMGLRALQRKLVPWHGQAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]