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The map label for this gene is soxC [H]

Identifier: 77456467

GI number: 77456467

Start: 281620

End: 282813

Strand: Reverse

Name: soxC [H]

Synonym: Pfl01_0239

Alternate gene names: 77456467

Gene position: 282813-281620 (Counterclockwise)

Preceding gene: 77456468

Following gene: 77456466

Centisome position: 4.39

GC content: 64.15

Gene sequence:

>1194_bases
ATGACTTTTTCCCATCCCGTCGCGGTCATCACCAGCGACGAGCAAGCCCTGATCGTCGCCAGCGACCTGGCCGAAGATTT
CCAGCGCGACAGCAACCTGCGCGACCGCGAACGCCGGCTGCCGCTGCCGGAGCTCGACGTGTTTTCCCGTTCCGGCCTGT
GGGGCATCAGCGTGCCCAAGGAGTACGGTGGCGCCGGCGTATCCAACGTGACCCTGGCCAAAGTCATCGCTTTGATCGCC
AGGGCCGATGGCTCGCTCGGGCAGATTCCACAGAACCATTTTTATGCCCTGGAAGTGCTCCGGGTGAACGGCAGCCACGA
GCAGAAACAACGTCTGTACGCCGAAGTCCTCGCCGGCCAGCGTTTTGGCAATGCCCTGGCAGAACTGGGCACCAGGACCG
CCCACGACCGTGTCACCCGCCTCGAACGCGACGGCAGCGGTTATCGCATCAACGGTCGCAAGTTCTATGCGACCGGCGCC
ATTTACGCCCAACGGATTCCAACGTCCGTGGTCGATGAAAACGGCGTGCAGCAACTGGCGTTCGTCCCGCGCGACAGCAA
AGGTCTGACCGTGATCGACGACTGGAGCGGCTTCGGCCAGCGCACCACTGGCAGCGGTTCGGTGGTGTTCGAAAACGTGT
ACGTCGCCGCCGAAGACGTCATTCCGTTCCAGAGCGCTTTCGAGCGCCCGACCCCGGTCGGCCCGTTGGCGCAGATCCTT
CACGCCGCCATCGACACCGGCATCGCCCGCGCCGCTTACGAAGACGCGTTGCACTTCGTGCGCAGCAAGACCCGTCCATG
GATCGATTCGGGCAACGACAAAGCCACCGAAGACCCGCTGACCCTCAAGAGCTTCGGCCACTTGAGCATTCGCCTGCACG
CCACCGAAGCCCTACTCGAACGTGCCGGCGAATTCCTCGACGCGGCCCAGGCCGAGACTAACGCCGAGACCGTTGCGGCA
GCCTCGATTGCCGTCGCCGAAGCACGGGCAATCAGCACCGAAATCTCCCTGGCCGCCGGTAGCACCCTGTTCGAACTGGC
CGGCAGCCAGGCCACCCTGATCGAGCACGGCCTCGACCGCCACTGGCGCAACGCCCGGGTACACACCCTGCACGACCCGG
TGCGCTGGAAGTATCACGCGGTGGGCAATTACTACCTCAACGATGAAAACCCGCCGCTGCGAGGGACCATCTGA

Upstream 100 bases:

>100_bases
ACCACGCGGTCGGCGCTTATCGCCTCAACGGCAAGTTGCCGGCTCGCCATTCCTGGATCTGACGACCCGAACACTTTTGA
CCAGATCTCTGGAGAAATAC

Downstream 100 bases:

>100_bases
TGAGCAAGAAAAAGATCCTGCTCAATGCGTTCAACATGAACTGCATCGGCCACATCAACCACGGGTTGTGGACCCATCCC
CGCGACACCTCGACCCGATA

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: DBT sulfur dioxygenase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTFSHPVAVITSDEQALIVASDLAEDFQRDSNLRDRERRLPLPELDVFSRSGLWGISVPKEYGGAGVSNVTLAKVIALIA
RADGSLGQIPQNHFYALEVLRVNGSHEQKQRLYAEVLAGQRFGNALAELGTRTAHDRVTRLERDGSGYRINGRKFYATGA
IYAQRIPTSVVDENGVQQLAFVPRDSKGLTVIDDWSGFGQRTTGSGSVVFENVYVAAEDVIPFQSAFERPTPVGPLAQIL
HAAIDTGIARAAYEDALHFVRSKTRPWIDSGNDKATEDPLTLKSFGHLSIRLHATEALLERAGEFLDAAQAETNAETVAA
ASIAVAEARAISTEISLAAGSTLFELAGSQATLIEHGLDRHWRNARVHTLHDPVRWKYHAVGNYYLNDENPPLRGTI

Sequences:

>Translated_397_residues
MTFSHPVAVITSDEQALIVASDLAEDFQRDSNLRDRERRLPLPELDVFSRSGLWGISVPKEYGGAGVSNVTLAKVIALIA
RADGSLGQIPQNHFYALEVLRVNGSHEQKQRLYAEVLAGQRFGNALAELGTRTAHDRVTRLERDGSGYRINGRKFYATGA
IYAQRIPTSVVDENGVQQLAFVPRDSKGLTVIDDWSGFGQRTTGSGSVVFENVYVAAEDVIPFQSAFERPTPVGPLAQIL
HAAIDTGIARAAYEDALHFVRSKTRPWIDSGNDKATEDPLTLKSFGHLSIRLHATEALLERAGEFLDAAQAETNAETVAA
ASIAVAEARAISTEISLAAGSTLFELAGSQATLIEHGLDRHWRNARVHTLHDPVRWKYHAVGNYYLNDENPPLRGTI
>Mature_396_residues
TFSHPVAVITSDEQALIVASDLAEDFQRDSNLRDRERRLPLPELDVFSRSGLWGISVPKEYGGAGVSNVTLAKVIALIAR
ADGSLGQIPQNHFYALEVLRVNGSHEQKQRLYAEVLAGQRFGNALAELGTRTAHDRVTRLERDGSGYRINGRKFYATGAI
YAQRIPTSVVDENGVQQLAFVPRDSKGLTVIDDWSGFGQRTTGSGSVVFENVYVAAEDVIPFQSAFERPTPVGPLAQILH
AAIDTGIARAAYEDALHFVRSKTRPWIDSGNDKATEDPLTLKSFGHLSIRLHATEALLERAGEFLDAAQAETNAETVAAA
SIAVAEARAISTEISLAAGSTLFELAGSQATLIEHGLDRHWRNARVHTLHDPVRWKYHAVGNYYLNDENPPLRGTI

Specific function: Part of a pathway to remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Sulfur dioxygenase which converts DBT to DBT-sulfone (DBTO2 or DBT 5,5-dioxide) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4501859, Length=379, Percent_Identity=23.4828496042216, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4557233, Length=352, Percent_Identity=24.4318181818182, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356377, Length=355, Percent_Identity=23.943661971831, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24646207, Length=238, Percent_Identity=26.890756302521, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 43390; Mature: 43259

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSHPVAVITSDEQALIVASDLAEDFQRDSNLRDRERRLPLPELDVFSRSGLWGISVPK
CCCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCCHHHHCCCCCCCCHHCCCCEEECCCCH
EYGGAGVSNVTLAKVIALIARADGSLGQIPQNHFYALEVLRVNGSHEQKQRLYAEVLAGQ
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHH
RFGNALAELGTRTAHDRVTRLERDGSGYRINGRKFYATGAIYAQRIPTSVVDENGVQQLA
HHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCEEEEEECCHHHHHCCCHHHCCCCCEEEE
FVPRDSKGLTVIDDWSGFGQRTTGSGSVVFENVYVAAEDVIPFQSAFERPTPVGPLAQIL
ECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEHHHCCCHHHHCCCCCCCCHHHHHH
HAAIDTGIARAAYEDALHFVRSKTRPWIDSGNDKATEDPLTLKSFGHLSIRLHATEALLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHH
RAGEFLDAAQAETNAETVAAASIAVAEARAISTEISLAAGSTLFELAGSQATLIEHGLDR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEHHCCCHHHHHCCCCHHHHHHHHHH
HWRNARVHTLHDPVRWKYHAVGNYYLNDENPPLRGTI
HHCCCEEEEECCCCCEEEEEECEEEECCCCCCCCCCC
>Mature Secondary Structure 
TFSHPVAVITSDEQALIVASDLAEDFQRDSNLRDRERRLPLPELDVFSRSGLWGISVPK
CCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCCHHHHCCCCCCCCHHCCCCEEECCCCH
EYGGAGVSNVTLAKVIALIARADGSLGQIPQNHFYALEVLRVNGSHEQKQRLYAEVLAGQ
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHH
RFGNALAELGTRTAHDRVTRLERDGSGYRINGRKFYATGAIYAQRIPTSVVDENGVQQLA
HHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCEEEEEECCHHHHHCCCHHHCCCCCEEEE
FVPRDSKGLTVIDDWSGFGQRTTGSGSVVFENVYVAAEDVIPFQSAFERPTPVGPLAQIL
ECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEHHHCCCHHHHCCCCCCCCHHHHHH
HAAIDTGIARAAYEDALHFVRSKTRPWIDSGNDKATEDPLTLKSFGHLSIRLHATEALLE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEHHHHHHH
RAGEFLDAAQAETNAETVAAASIAVAEARAISTEISLAAGSTLFELAGSQATLIEHGLDR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEHHCCCHHHHHCCCCHHHHHHHHHH
HWRNARVHTLHDPVRWKYHAVGNYYLNDENPPLRGTI
HHCCCEEEEECCCCCEEEEEECEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961424; 7574582 [H]