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The map label for this gene is soxC [H]

Identifier: 77456468

GI number: 77456468

Start: 282852

End: 284093

Strand: Reverse

Name: soxC [H]

Synonym: Pfl01_0240

Alternate gene names: 77456468

Gene position: 284093-282852 (Counterclockwise)

Preceding gene: 77456469

Following gene: 77456467

Centisome position: 4.41

GC content: 63.77

Gene sequence:

>1242_bases
ATGTCCAGTCTGGCAGACGCAAACGTCCAGAGTGACCTGGACATCGCCCCGTTGTTGTTGCCTGCACAAGTGCTGCGCAA
CGACGCTCAAGCCATCAAGGCCGCCCATGAGCTGGCGCAAGTCGCCCGCGTGCAGGCCGCCAAACGTGATCGCCAGCGCA
AGCTGCCGTGGTCGGAAATCGAACAGTTCACCCGCAGCGGCCTCGGCAGCATCGCGATTCCGCGCGAATACGGCGGTCCG
CAGGTTTCCTTCGTGACCCTGGCCGAGGTGTTCGCGATCATTTCGGCAGCCGACCCGGCATTGGGGCAGATCCCGCAGAA
CCAGTTCGGCATCATCAACCTGATCCTCGGCAGCGCCACCGAACAGCAGAAAAAACATTTGCTACAGAGTGTGCTCGAAG
GCTGGCGCATCGGTAATGCCGGGCCGGAGCGTGGCACCAAGAACACCCTGGAATTGAAAGCGCGCATCACCGCCGACGGC
GATGACTACGTGATCAATGGCCAGAAGTTCTACTCCACCGGCGCCCTGTTCGCCCACTGGGTCGCGGTCAAGGCGCTGAA
CGATGACGGTAAACAGGTTTTGGCCTTCGTCCGTCGGGGCACGCCGGGCCTGCGCATCGTCGATGACTGGTCCGGTTTCG
GCCAGCGCACCACCGCCAGTGGCACGATCCTGTTGAACAACGTGCGGGTCGACGCCGGCCTCGTGGTGGACAACTGGAAG
ATCAACGAAAAGCCCAACACCCAGGGCGCGGTGTCGCAGCTGATTCAAGCGGCGATCGACGCCGGCATCGCCCGTGGCGC
CATCGATGACGCCATTGAGTTCGTCAAGACTCGCGCCCGGCCGTGGATCGACGCTAACGTCGAACGGGCCAGCGATGACC
TCTACGTCATCGCCGACATCGGCAAACTGAAAATCGAACTGCACGCCGCCGAAGCGCTGCTGCGCAAGGCCGGGCAGGTA
CTGGATCAGGTGCACGCCGCACCGCTGACTGCCGAGTCCGCCGCCCGCGCCTCGATTGCCGTGGCCGAAGCCAAGGTGCT
GACCACCGAGATCTCGCTGCTGGCCAGCGAAAAACTCTTCGAACTGGCCGGCAGCCGCGCGACCCTCGCCGAATTCAACC
TCGACCGTCACTGGCGCAACGCCCGGGTGCACACCCTGCACGACCCGGTGCGCTGGAAGTACCACGCGGTCGGCGCTTAT
CGCCTCAACGGCAAGTTGCCGGCTCGCCATTCCTGGATCTGA

Upstream 100 bases:

>100_bases
CGGCGTTTTTCATGAGATGTGAGGTAGGTAACATGGTCCGGAACACAATCACCCCAGTGCAGATCGCCAGGGCATTGCGT
GCAGCCAGGGAGCGGCACTG

Downstream 100 bases:

>100_bases
CGACCCGAACACTTTTGACCAGATCTCTGGAGAAATACATGACTTTTTCCCATCCCGTCGCGGTCATCACCAGCGACGAG
CAAGCCCTGATCGTCGCCAG

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: DBT sulfur dioxygenase [H]

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MSSLADANVQSDLDIAPLLLPAQVLRNDAQAIKAAHELAQVARVQAAKRDRQRKLPWSEIEQFTRSGLGSIAIPREYGGP
QVSFVTLAEVFAIISAADPALGQIPQNQFGIINLILGSATEQQKKHLLQSVLEGWRIGNAGPERGTKNTLELKARITADG
DDYVINGQKFYSTGALFAHWVAVKALNDDGKQVLAFVRRGTPGLRIVDDWSGFGQRTTASGTILLNNVRVDAGLVVDNWK
INEKPNTQGAVSQLIQAAIDAGIARGAIDDAIEFVKTRARPWIDANVERASDDLYVIADIGKLKIELHAAEALLRKAGQV
LDQVHAAPLTAESAARASIAVAEAKVLTTEISLLASEKLFELAGSRATLAEFNLDRHWRNARVHTLHDPVRWKYHAVGAY
RLNGKLPARHSWI

Sequences:

>Translated_413_residues
MSSLADANVQSDLDIAPLLLPAQVLRNDAQAIKAAHELAQVARVQAAKRDRQRKLPWSEIEQFTRSGLGSIAIPREYGGP
QVSFVTLAEVFAIISAADPALGQIPQNQFGIINLILGSATEQQKKHLLQSVLEGWRIGNAGPERGTKNTLELKARITADG
DDYVINGQKFYSTGALFAHWVAVKALNDDGKQVLAFVRRGTPGLRIVDDWSGFGQRTTASGTILLNNVRVDAGLVVDNWK
INEKPNTQGAVSQLIQAAIDAGIARGAIDDAIEFVKTRARPWIDANVERASDDLYVIADIGKLKIELHAAEALLRKAGQV
LDQVHAAPLTAESAARASIAVAEAKVLTTEISLLASEKLFELAGSRATLAEFNLDRHWRNARVHTLHDPVRWKYHAVGAY
RLNGKLPARHSWI
>Mature_412_residues
SSLADANVQSDLDIAPLLLPAQVLRNDAQAIKAAHELAQVARVQAAKRDRQRKLPWSEIEQFTRSGLGSIAIPREYGGPQ
VSFVTLAEVFAIISAADPALGQIPQNQFGIINLILGSATEQQKKHLLQSVLEGWRIGNAGPERGTKNTLELKARITADGD
DYVINGQKFYSTGALFAHWVAVKALNDDGKQVLAFVRRGTPGLRIVDDWSGFGQRTTASGTILLNNVRVDAGLVVDNWKI
NEKPNTQGAVSQLIQAAIDAGIARGAIDDAIEFVKTRARPWIDANVERASDDLYVIADIGKLKIELHAAEALLRKAGQVL
DQVHAAPLTAESAARASIAVAEAKVLTTEISLLASEKLFELAGSRATLAEFNLDRHWRNARVHTLHDPVRWKYHAVGAYR
LNGKLPARHSWI

Specific function: Part of a pathway to remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Sulfur dioxygenase which converts DBT to DBT-sulfone (DBTO2 or DBT 5,5-dioxide) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4501859, Length=383, Percent_Identity=25.3263707571802, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557233, Length=359, Percent_Identity=23.9554317548747, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=352, Percent_Identity=24.4318181818182, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17534899, Length=377, Percent_Identity=23.342175066313, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=298, Percent_Identity=26.1744966442953, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=23.2, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17506239, Length=355, Percent_Identity=22.5352112676056, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646207, Length=398, Percent_Identity=24.8743718592965, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=354, Percent_Identity=24.8587570621469, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666513, Length=384, Percent_Identity=23.6979166666667, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 44971; Mature: 44839

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLADANVQSDLDIAPLLLPAQVLRNDAQAIKAAHELAQVARVQAAKRDRQRKLPWSEI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EQFTRSGLGSIAIPREYGGPQVSFVTLAEVFAIISAADPALGQIPQNQFGIINLILGSAT
HHHHHCCCCCEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEECCCC
EQQKKHLLQSVLEGWRIGNAGPERGTKNTLELKARITADGDDYVINGQKFYSTGALFAHW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEECCCEEECCHHHHHHH
VAVKALNDDGKQVLAFVRRGTPGLRIVDDWSGFGQRTTASGTILLNNVRVDAGLVVDNWK
HHHEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEECEEEEECEE
INEKPNTQGAVSQLIQAAIDAGIARGAIDDAIEFVKTRARPWIDANVERASDDLYVIADI
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCEEEEEEC
GKLKIELHAAEALLRKAGQVLDQVHAAPLTAESAARASIAVAEAKVLTTEISLLASEKLF
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAGSRATLAEFNLDRHWRNARVHTLHDPVRWKYHAVGAYRLNGKLPARHSWI
HHCCCCCCHHHCCCHHHHCCCEEEEECCCCCEEEEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SSLADANVQSDLDIAPLLLPAQVLRNDAQAIKAAHELAQVARVQAAKRDRQRKLPWSEI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
EQFTRSGLGSIAIPREYGGPQVSFVTLAEVFAIISAADPALGQIPQNQFGIINLILGSAT
HHHHHCCCCCEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEEEEECCCC
EQQKKHLLQSVLEGWRIGNAGPERGTKNTLELKARITADGDDYVINGQKFYSTGALFAHW
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEECCCEEECCHHHHHHH
VAVKALNDDGKQVLAFVRRGTPGLRIVDDWSGFGQRTTASGTILLNNVRVDAGLVVDNWK
HHHEEECCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEECEEEEECEE
INEKPNTQGAVSQLIQAAIDAGIARGAIDDAIEFVKTRARPWIDANVERASDDLYVIADI
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCEEEEEEC
GKLKIELHAAEALLRKAGQVLDQVHAAPLTAESAARASIAVAEAKVLTTEISLLASEKLF
CEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAGSRATLAEFNLDRHWRNARVHTLHDPVRWKYHAVGAYRLNGKLPARHSWI
HHCCCCCCHHHCCCHHHHCCCEEEEECCCCCEEEEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961424; 7574582 [H]