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The map label for this gene is nahR [H]

Identifier: 77456369

GI number: 77456369

Start: 169940

End: 170857

Strand: Direct

Name: nahR [H]

Synonym: Pfl01_0141

Alternate gene names: 77456369

Gene position: 169940-170857 (Clockwise)

Preceding gene: 77456368

Following gene: 77456370

Centisome position: 2.64

GC content: 66.12

Gene sequence:

>918_bases
ATGCAACTCCCGGACATGAACCTGTTGGTCGCCCTCGACGCCTTGCTTGACGAGGGCAGCGTGGTCGGCGCCGCGCGGCG
GATGAACCTCAGCCCGGCGGCCATGAGCCGCACGCTGACGCGGATTCGCGAAGCCATTGGCGATCCGATTCTGGTGCGTG
CCGGCCGCGGTCTGGTGCCGACGCCCAAGGCCCTGGAACTGCGCGAGCAGGTGCGGGATGTGGTCGAGCAGGCGGCGCTG
CTGTTTCGCTCGGCCGATGCGGTGGAACTGGGCACGTTGCGCCGGCGCTTCAGCATTCGCGCCAACGATTTTTTCGTTGG
CGTGTACGGCGGCAAGCTGTTCGACACCCTCGATCAACTGGCGCCGCACTGTGAGTTGCGTTTCGTTCCCGAGGGGGATG
GCGACGATGAAGCGCTGCGCGAAGGGCGCATCGACCTGAGTGTCAGCAATACGCGCCCGGTGACGCCGGAAGTCAAAGTG
CAGAACCTGTTTTCCACCCACTTCGTCGGTCTGGTGCGCGAGGATCATCCGCTGCTGGACGGCGAGATCACGGCCGAACG
CTATGCCGGGTTTTCCCACATCAGCATGTCCCGCCGGGGCATCGCCCGTGGCCCCATCGACACTGCTTTGAATGCCCTGG
GGTTGGAGCGGCGGGTGGCAGTGATTGCGCCGAGTTTCCACGCGGCGATGTTCGCCCTGCCGGACTCCGACCTGATCCTG
CCAGTGCCCAAGGAAGCGCTGCTCAGCGTGCGGCGGCTGGGCTTGAAGCTGCGCTCGTTCGACCTGCCGATCCCGCTGCC
GACGCTGATGCTGACCCAGGCCTGGCACCCGCGTTTTGACAAGGACCCGGCCCACCGCTGGCTGCGGGAAACCCTCAAGA
CCTGCTGCGACGAAACCTGGCTGGCGGCACAGCCCTGA

Upstream 100 bases:

>100_bases
CTGGAGCGGGTGACGGTGAAACGCTGGGGGATGCAGCGCTGATTTTCTGATCTGCTAGCATTGCGTGCGAATCAATCCTG
ATCGGTCACGAGTGCTCAGC

Downstream 100 bases:

>100_bases
CAATTGCGTCCGGTGCACTTATAAACTGCCAAGAAGTCAATTTTCGTCAGCACTAAGCCCTACTACCATGCTCCGGTATT
TTTCCCTCCGGAGTTTGCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQLPDMNLLVALDALLDEGSVVGAARRMNLSPAAMSRTLTRIREAIGDPILVRAGRGLVPTPKALELREQVRDVVEQAAL
LFRSADAVELGTLRRRFSIRANDFFVGVYGGKLFDTLDQLAPHCELRFVPEGDGDDEALREGRIDLSVSNTRPVTPEVKV
QNLFSTHFVGLVREDHPLLDGEITAERYAGFSHISMSRRGIARGPIDTALNALGLERRVAVIAPSFHAAMFALPDSDLIL
PVPKEALLSVRRLGLKLRSFDLPIPLPTLMLTQAWHPRFDKDPAHRWLRETLKTCCDETWLAAQP

Sequences:

>Translated_305_residues
MQLPDMNLLVALDALLDEGSVVGAARRMNLSPAAMSRTLTRIREAIGDPILVRAGRGLVPTPKALELREQVRDVVEQAAL
LFRSADAVELGTLRRRFSIRANDFFVGVYGGKLFDTLDQLAPHCELRFVPEGDGDDEALREGRIDLSVSNTRPVTPEVKV
QNLFSTHFVGLVREDHPLLDGEITAERYAGFSHISMSRRGIARGPIDTALNALGLERRVAVIAPSFHAAMFALPDSDLIL
PVPKEALLSVRRLGLKLRSFDLPIPLPTLMLTQAWHPRFDKDPAHRWLRETLKTCCDETWLAAQP
>Mature_305_residues
MQLPDMNLLVALDALLDEGSVVGAARRMNLSPAAMSRTLTRIREAIGDPILVRAGRGLVPTPKALELREQVRDVVEQAAL
LFRSADAVELGTLRRRFSIRANDFFVGVYGGKLFDTLDQLAPHCELRFVPEGDGDDEALREGRIDLSVSNTRPVTPEVKV
QNLFSTHFVGLVREDHPLLDGEITAERYAGFSHISMSRRGIARGPIDTALNALGLERRVAVIAPSFHAAMFALPDSDLIL
PVPKEALLSVRRLGLKLRSFDLPIPLPTLMLTQAWHPRFDKDPAHRWLRETLKTCCDETWLAAQP

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=300, Percent_Identity=26, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87081684, Length=322, Percent_Identity=22.360248447205, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786820, Length=275, Percent_Identity=21.4545454545455, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081766, Length=190, Percent_Identity=25.7894736842105, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33849; Mature: 33849

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPDMNLLVALDALLDEGSVVGAARRMNLSPAAMSRTLTRIREAIGDPILVRAGRGLVP
CCCCCCHHHHHHHHHHCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCC
TPKALELREQVRDVVEQAALLFRSADAVELGTLRRRFSIRANDFFVGVYGGKLFDTLDQL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCEEEEEEECCHHHHHHHHH
APHCELRFVPEGDGDDEALREGRIDLSVSNTRPVTPEVKVQNLFSTHFVGLVREDHPLLD
CCCCEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
GEITAERYAGFSHISMSRRGIARGPIDTALNALGLERRVAVIAPSFHAAMFALPDSDLIL
CCCCHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCHHCEEEEECCCHHHEEEECCCCCEEE
PVPKEALLSVRRLGLKLRSFDLPIPLPTLMLTQAWHPRFDKDPAHRWLRETLKTCCDETW
ECCHHHHHHHHHHCCHHEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
LAAQP
CCCCC
>Mature Secondary Structure
MQLPDMNLLVALDALLDEGSVVGAARRMNLSPAAMSRTLTRIREAIGDPILVRAGRGLVP
CCCCCCHHHHHHHHHHCCCCEEHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCC
TPKALELREQVRDVVEQAALLFRSADAVELGTLRRRFSIRANDFFVGVYGGKLFDTLDQL
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCEEEEEEECCHHHHHHHHH
APHCELRFVPEGDGDDEALREGRIDLSVSNTRPVTPEVKVQNLFSTHFVGLVREDHPLLD
CCCCEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
GEITAERYAGFSHISMSRRGIARGPIDTALNALGLERRVAVIAPSFHAAMFALPDSDLIL
CCCCHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCHHCEEEEECCCHHHEEEECCCCCEEE
PVPKEALLSVRRLGLKLRSFDLPIPLPTLMLTQAWHPRFDKDPAHRWLRETLKTCCDETW
ECCHHHHHHHHHHCCHHEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
LAAQP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]