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The map label for this gene is gph [C]

Identifier: 77456320

GI number: 77456320

Start: 98895

End: 99545

Strand: Direct

Name: gph [C]

Synonym: Pfl01_0092

Alternate gene names: 77456320

Gene position: 98895-99545 (Clockwise)

Preceding gene: 77456319

Following gene: 77456322

Centisome position: 1.54

GC content: 59.6

Gene sequence:

>651_bases
ATGCATTACCAGACCGTACTGTTCGACCTTGACGGCACCCTCACCGACCCGCGTGAGGGCATCACCCGTTCCATCCAGTT
CGCCTTGAGCAAACTCGGCATCGACGAGCCGGATCTGACCAGACTGGAACACTTCATCGGCCCGCCGCTGTTGCAAGCGT
TCATGCAGTTTTATGGTTTCGACGAAGCCAAGGCTTGGGAGGCGGTGAATTACTACCGCGAGCGCTTCAAGGTTACCGGC
CTGTACGAGAACCGGGTGTTCGACGGCGTCACGCCGTTGTTGGAAACCCTGGGCAGCCAGGGCCGGCAGTTGTATATCGC
GACGTCGAAGCCTTGGGTGTTCGCCCGGGAAATCGCCCGGCACTTTGATTTCGCCAAACACTTCAAGGTGATCTACGGCA
GCGAACTGGACGGCACCCGTACCAACAAGGTCGAGCTGATTGCCCACCTGATCGCCGAGGAAAGACTGGACCCGGCCAGT
ACGTTGATGATCGGTGACCGCAAACACGACCTGATCGGTGCTCGCAGCAACGGTCTGGACGCGGCGGCCGTGGGTTACGG
TTTTGGCAGCCATGAAGAGCTGAGCGCTGAAGCACCGGCGTATCACTTCGAGACGCTGGCGGAGCTGCATCAGGCGTTTT
TGCAGCGCTGA

Upstream 100 bases:

>100_bases
TTCACCTACAGCGCGGCGAACTACGTGAAGCTCAAGGACCTGCATCTGGCTGAAGGCTACGACCAGCTCTGACTTTTCTT
TCTACCGCCCGGGATTTTTC

Downstream 100 bases:

>100_bases
TCGTCAATCCGGGCGAAGGGCAGCCAGCTCACGCAGTGCTGCCTTGCGCTTGTCCGCCGGCAATTTACCCAGCTGTTCGA
CCCGCGCATAAAACTGCGGC

Product: HAD family hydrolase

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MHYQTVLFDLDGTLTDPREGITRSIQFALSKLGIDEPDLTRLEHFIGPPLLQAFMQFYGFDEAKAWEAVNYYRERFKVTG
LYENRVFDGVTPLLETLGSQGRQLYIATSKPWVFAREIARHFDFAKHFKVIYGSELDGTRTNKVELIAHLIAEERLDPAS
TLMIGDRKHDLIGARSNGLDAAAVGYGFGSHEELSAEAPAYHFETLAELHQAFLQR

Sequences:

>Translated_216_residues
MHYQTVLFDLDGTLTDPREGITRSIQFALSKLGIDEPDLTRLEHFIGPPLLQAFMQFYGFDEAKAWEAVNYYRERFKVTG
LYENRVFDGVTPLLETLGSQGRQLYIATSKPWVFAREIARHFDFAKHFKVIYGSELDGTRTNKVELIAHLIAEERLDPAS
TLMIGDRKHDLIGARSNGLDAAAVGYGFGSHEELSAEAPAYHFETLAELHQAFLQR
>Mature_216_residues
MHYQTVLFDLDGTLTDPREGITRSIQFALSKLGIDEPDLTRLEHFIGPPLLQAFMQFYGFDEAKAWEAVNYYRERFKVTG
LYENRVFDGVTPLLETLGSQGRQLYIATSKPWVFAREIARHFDFAKHFKVIYGSELDGTRTNKVELIAHLIAEERLDPAS
TLMIGDRKHDLIGARSNGLDAAAVGYGFGSHEELSAEAPAYHFETLAELHQAFLQR

Specific function: Specifically dephosphorylates nucleoside 5'- monophosphates to nucleosides and inorganic phosphate. Displays high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 24512; Mature: 24512

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYQTVLFDLDGTLTDPREGITRSIQFALSKLGIDEPDLTRLEHFIGPPLLQAFMQFYGF
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCC
DEAKAWEAVNYYRERFKVTGLYENRVFDGVTPLLETLGSQGRQLYIATSKPWVFAREIAR
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
HFDFAKHFKVIYGSELDGTRTNKVELIAHLIAEERLDPASTLMIGDRKHDLIGARSNGLD
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHEEECCCCHHHCCCCCCCCC
AAAVGYGFGSHEELSAEAPAYHFETLAELHQAFLQR
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHYQTVLFDLDGTLTDPREGITRSIQFALSKLGIDEPDLTRLEHFIGPPLLQAFMQFYGF
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHCC
DEAKAWEAVNYYRERFKVTGLYENRVFDGVTPLLETLGSQGRQLYIATSKPWVFAREIAR
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHH
HFDFAKHFKVIYGSELDGTRTNKVELIAHLIAEERLDPASTLMIGDRKHDLIGARSNGLD
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHEEECCCCHHHCCCCCCCCC
AAAVGYGFGSHEELSAEAPAYHFETLAELHQAFLQR
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]