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The map label for this gene is cynT [H]

Identifier: 77456310

GI number: 77456310

Start: 86861

End: 87592

Strand: Reverse

Name: cynT [H]

Synonym: Pfl01_0082

Alternate gene names: 77456310

Gene position: 87592-86861 (Counterclockwise)

Preceding gene: 77456311

Following gene: 77456309

Centisome position: 1.36

GC content: 59.56

Gene sequence:

>732_bases
ATGAGTGACAAGGATAAACAGCCGTTGGCTGCGTCGGCGCAAGCCGCCCCTGTGGCGGAATCCGCCGATGCAGCGTTGAA
GCGTATCGTTGACGGCTTTTTGCATTTTCATCATGAGGTCTTTCCGCAGCAGGAAGAACTCTTCAAGAAACTCGCCACGG
CACAGTCGCCACGGGCGATGTTCATCACCTGCGCCGACTCGCGCATCGTGCCCGAACTGATCACCCAGAGTTCGCCCGGC
GATCTGTTCGTGACCCGTAACGTCGGCAACGTCGTGCCACCCTACGGCCAGATGAACGGCGGCGTTTCCACCGCCATCGA
ATACGCGGTCCTGGCCCTCGGCGTGCAGCACATCATCATTTGCGGCCACTCCGACTGCGGCGCCATGCGGGCGGTGCTCA
ACCCGGACAGCCTGGAAAAAATGCCGACGGTCAAAGCCTGGCTGCGCCACGCCGAAGTCGCGAAAACCATGGTGCATGAC
AACTGCAACTGCACCGACGAAAAAGAAAGCATGCCGATCCTCACCGAGGAGAACGTCATCGCCCAACTGCAGCACTTGCG
TACCCATCCTTCGGTAGCCTCGCGCATGGCGAACGGTCATTTGTTCATCCATGGCTGGGTCTACAACATCGAAACCAGCG
AAATCAAAGCTTACGACGCGGATCAGGGTTGCTTCCTGCCGCTCGACGGCAGCCATCCGATTCCGGTGGCGACGCCCAAA
GCGCGCTTCTAA

Upstream 100 bases:

>100_bases
TGACTGACGGGTCGGGATGACCCGGATGTTCTAAACAGCCACTGGCTTCACACCGGAATACACGGGAACGACTCCCCGAA
TCCGCCAATGAGGATGAATC

Downstream 100 bases:

>100_bases
ATCCTCCTAAAAATCCGTGTGGTTTGACGCCGGCCGCTGTTTCAGCGGCCAGGCCTTGCCACGCCTGAAGAAAACTTCGG
GAGAATCGCCATGCGTGCGG

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSDKDKQPLAASAQAAPVAESADAALKRIVDGFLHFHHEVFPQQEELFKKLATAQSPRAMFITCADSRIVPELITQSSPG
DLFVTRNVGNVVPPYGQMNGGVSTAIEYAVLALGVQHIIICGHSDCGAMRAVLNPDSLEKMPTVKAWLRHAEVAKTMVHD
NCNCTDEKESMPILTEENVIAQLQHLRTHPSVASRMANGHLFIHGWVYNIETSEIKAYDADQGCFLPLDGSHPIPVATPK
ARF

Sequences:

>Translated_243_residues
MSDKDKQPLAASAQAAPVAESADAALKRIVDGFLHFHHEVFPQQEELFKKLATAQSPRAMFITCADSRIVPELITQSSPG
DLFVTRNVGNVVPPYGQMNGGVSTAIEYAVLALGVQHIIICGHSDCGAMRAVLNPDSLEKMPTVKAWLRHAEVAKTMVHD
NCNCTDEKESMPILTEENVIAQLQHLRTHPSVASRMANGHLFIHGWVYNIETSEIKAYDADQGCFLPLDGSHPIPVATPK
ARF
>Mature_242_residues
SDKDKQPLAASAQAAPVAESADAALKRIVDGFLHFHHEVFPQQEELFKKLATAQSPRAMFITCADSRIVPELITQSSPGD
LFVTRNVGNVVPPYGQMNGGVSTAIEYAVLALGVQHIIICGHSDCGAMRAVLNPDSLEKMPTVKAWLRHAEVAKTMVHDN
CNCTDEKESMPILTEENVIAQLQHLRTHPSVASRMANGHLFIHGWVYNIETSEIKAYDADQGCFLPLDGSHPIPVATPKA
RF

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=220, Percent_Identity=50.4545454545455, Blast_Score=227, Evalue=6e-61,
Organism=Escherichia coli, GI1786318, Length=176, Percent_Identity=35.2272727272727, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25147564, Length=241, Percent_Identity=27.8008298755187, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI115532990, Length=244, Percent_Identity=27.4590163934426, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324292, Length=166, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24645213, Length=240, Percent_Identity=27.5, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26548; Mature: 26416

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKDKQPLAASAQAAPVAESADAALKRIVDGFLHFHHEVFPQQEELFKKLATAQSPRAM
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEE
FITCADSRIVPELITQSSPGDLFVTRNVGNVVPPYGQMNGGVSTAIEYAVLALGVQHIII
EEEECCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
CGHSDCGAMRAVLNPDSLEKMPTVKAWLRHAEVAKTMVHDNCNCTDEKESMPILTEENVI
ECCCCHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECHHHH
AQLQHLRTHPSVASRMANGHLFIHGWVYNIETSEIKAYDADQGCFLPLDGSHPIPVATPK
HHHHHHHCCHHHHHHHCCCEEEEEEEEEEEEHHHEEEEECCCCCEEECCCCCCCCCCCCC
ARF
CCC
>Mature Secondary Structure 
SDKDKQPLAASAQAAPVAESADAALKRIVDGFLHFHHEVFPQQEELFKKLATAQSPRAM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEE
FITCADSRIVPELITQSSPGDLFVTRNVGNVVPPYGQMNGGVSTAIEYAVLALGVQHIII
EEEECCCCHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEE
CGHSDCGAMRAVLNPDSLEKMPTVKAWLRHAEVAKTMVHDNCNCTDEKESMPILTEENVI
ECCCCHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECHHHH
AQLQHLRTHPSVASRMANGHLFIHGWVYNIETSEIKAYDADQGCFLPLDGSHPIPVATPK
HHHHHHHCCHHHHHHHCCCEEEEEEEEEEEEHHHEEEEECCCCCEEECCCCCCCCCCCCC
ARF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]