Click here to switch to the map view.

The map label for this gene is algB [H]

Identifier: 77456274

GI number: 77456274

Start: 49441

End: 50787

Strand: Direct

Name: algB [H]

Synonym: Pfl01_0046

Alternate gene names: 77456274

Gene position: 49441-50787 (Clockwise)

Preceding gene: 77456268

Following gene: 77456275

Centisome position: 0.77

GC content: 62.73

Gene sequence:

>1347_bases
ATGGAATCAGCCACTGAGCACCAAGGCCGCATTCTGCTGGTGGACGATGAATCCGCCATCCTGCGAACCTTTCGTTATTG
CCTCGAAGACGAAGGTTATACCGTCGCCACCGCCAACAGTGCGGCTCAGGCTGACGCGCTGCTGCAACGCCAGGTGTTCG
ACCTGTGCTTCCTTGATTTACGCCTGGGTGAAGACAACGGCCTCGATGTACTCGCGCAGATGCGCATTCAGGCGCCGTGG
ATGCGGGTGGTCATCGTTACCGCCCATTCGGCCGTCGATACCGCGGTAGACGCGATTCAGGCCGGCGCTGCCGATTATCT
GGTCAAACCGTGCAGCCCGGATCAATTGCGCCTGGCGACCGCCAAGCAGCTTGAAGTGCGCCAGCTGTCGGCGCGTCTGG
AAGCCCTCGAAGGCGAGATCCGCAAACCCAAGGACGGCCTCGATTCCCACAGCCCGGCGATGAAAGTCGTACTGGAAACC
GCGCGGCAAGTGGCGGGCACCGACGCCAACATCCTGATCCTCGGCGAGTCCGGCACCGGTAAAGGTGAGCTGGCCCGGGC
GATTCACGGCTGGAGCAAGCGCGAGAAGAAATCCTGTGTGACCATCAATTGCCCGTCACTGACCGCCGAATTAATGGAGA
GCGAGCTGTTTGGTCACAGTCGTGGCGCCTTCACCGGGGCCAGCGAAAGCACGCTCGGTCGGGTCAATCAGGCCGATGGC
GGTACGCTGTTTCTCGACGAGATCGGCGATTTTCCGCTGACATTGCAACCCAAGTTGCTGCGGTTCATTCAGGACAAGGA
ATATGAGCGGGTAGGGGATCCGGTCACCCGCCGCGCCGATGTGCGCATCCTCGCCGCCACCAACCTCAATCTTGAGGACA
TGGTGCGCGACGGCCGTTTCCGTGAAGACCTGCTCTATCGCCTGAACGTCATCACCCTGCATTTGCCGCCGCTGCGCGAG
CGGGCCGAAGACATCCTGACCCTGGCCGACCGTTTCCTCGCCCGTTTCGTGAAGGAGTATGCGCGTCCGGCACGGGGCTT
CAGCGACGAGGCTCGCGAAGCACTGCTGGGCTACCGTTGGCCCGGCAACATCCGTGAGCTGCGCAACGTGGTCGAGCGGG
CGAGCATCATCTGCCCGCAGGAGCGCGTGGAAATCAGCCACCTCGGCATGGCCGAGCAACCGGCCAACAACGCGCCACGG
GTCGGCGCCGCGCTGAGCCTCGACGAGCTGGAAAAGGCTCACATCGGCGCAGTACTGGCGACCGCCGGGACCCTCGATCA
GGCTGCCAAGACTCTGGGGATCGACGCCTCGACCCTGTATCGCAAGCGCAAGCAGTACAACCTGTGA

Upstream 100 bases:

>100_bases
AGCTACCCTGCTATGACTGGAATCGATCAGAATCAACCATGCAACTTGCCCGATTTTTCCGGGACTAACCCAAGACATTC
ACTTATGGAGCGTAGGAAAA

Downstream 100 bases:

>100_bases
GCATCCGCCGATGAAACTGGCGATGAAGTTGCGGACTCGCTTGTTCCTGAGCATTTCCGCGCTGATCACCGTGGCCTTGC
TCGGGTTGATGCTCGGGCTG

Product: two-component response regulator AlgB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MESATEHQGRILLVDDESAILRTFRYCLEDEGYTVATANSAAQADALLQRQVFDLCFLDLRLGEDNGLDVLAQMRIQAPW
MRVVIVTAHSAVDTAVDAIQAGAADYLVKPCSPDQLRLATAKQLEVRQLSARLEALEGEIRKPKDGLDSHSPAMKVVLET
ARQVAGTDANILILGESGTGKGELARAIHGWSKREKKSCVTINCPSLTAELMESELFGHSRGAFTGASESTLGRVNQADG
GTLFLDEIGDFPLTLQPKLLRFIQDKEYERVGDPVTRRADVRILAATNLNLEDMVRDGRFREDLLYRLNVITLHLPPLRE
RAEDILTLADRFLARFVKEYARPARGFSDEAREALLGYRWPGNIRELRNVVERASIICPQERVEISHLGMAEQPANNAPR
VGAALSLDELEKAHIGAVLATAGTLDQAAKTLGIDASTLYRKRKQYNL

Sequences:

>Translated_448_residues
MESATEHQGRILLVDDESAILRTFRYCLEDEGYTVATANSAAQADALLQRQVFDLCFLDLRLGEDNGLDVLAQMRIQAPW
MRVVIVTAHSAVDTAVDAIQAGAADYLVKPCSPDQLRLATAKQLEVRQLSARLEALEGEIRKPKDGLDSHSPAMKVVLET
ARQVAGTDANILILGESGTGKGELARAIHGWSKREKKSCVTINCPSLTAELMESELFGHSRGAFTGASESTLGRVNQADG
GTLFLDEIGDFPLTLQPKLLRFIQDKEYERVGDPVTRRADVRILAATNLNLEDMVRDGRFREDLLYRLNVITLHLPPLRE
RAEDILTLADRFLARFVKEYARPARGFSDEAREALLGYRWPGNIRELRNVVERASIICPQERVEISHLGMAEQPANNAPR
VGAALSLDELEKAHIGAVLATAGTLDQAAKTLGIDASTLYRKRKQYNL
>Mature_448_residues
MESATEHQGRILLVDDESAILRTFRYCLEDEGYTVATANSAAQADALLQRQVFDLCFLDLRLGEDNGLDVLAQMRIQAPW
MRVVIVTAHSAVDTAVDAIQAGAADYLVKPCSPDQLRLATAKQLEVRQLSARLEALEGEIRKPKDGLDSHSPAMKVVLET
ARQVAGTDANILILGESGTGKGELARAIHGWSKREKKSCVTINCPSLTAELMESELFGHSRGAFTGASESTLGRVNQADG
GTLFLDEIGDFPLTLQPKLLRFIQDKEYERVGDPVTRRADVRILAATNLNLEDMVRDGRFREDLLYRLNVITLHLPPLRE
RAEDILTLADRFLARFVKEYARPARGFSDEAREALLGYRWPGNIRELRNVVERASIICPQERVEISHLGMAEQPANNAPR
VGAALSLDELEKAHIGAVLATAGTLDQAAKTLGIDASTLYRKRKQYNL

Specific function: Positive regulator of the alginate biosynthetic gene algD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=439, Percent_Identity=43.0523917995444, Blast_Score=318, Evalue=4e-88,
Organism=Escherichia coli, GI1788550, Length=459, Percent_Identity=39.6514161220044, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1790299, Length=472, Percent_Identity=37.5, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1788905, Length=442, Percent_Identity=37.7828054298643, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI87082117, Length=227, Percent_Identity=52.863436123348, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789087, Length=300, Percent_Identity=45.3333333333333, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789233, Length=304, Percent_Identity=43.75, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=47.8448275862069, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082152, Length=250, Percent_Identity=44.8, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=37.5, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=40.3125, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789828, Length=317, Percent_Identity=33.7539432176656, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081858, Length=329, Percent_Identity=29.7872340425532, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789809, Length=107, Percent_Identity=33.6448598130841, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790552, Length=108, Percent_Identity=31.4814814814815, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49481; Mature: 49481

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESATEHQGRILLVDDESAILRTFRYCLEDEGYTVATANSAAQADALLQRQVFDLCFLDL
CCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHE
RLGEDNGLDVLAQMRIQAPWMRVVIVTAHSAVDTAVDAIQAGAADYLVKPCSPDQLRLAT
EECCCCCHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHHCCCHHHEECCCCCCCEEHHH
AKQLEVRQLSARLEALEGEIRKPKDGLDSHSPAMKVVLETARQVAGTDANILILGESGTG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
KGELARAIHGWSKREKKSCVTINCPSLTAELMESELFGHSRGAFTGASESTLGRVNQADG
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCC
GTLFLDEIGDFPLTLQPKLLRFIQDKEYERVGDPVTRRADVRILAATNLNLEDMVRDGRF
CEEEHHCCCCCCCEECHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCHHHHHHCCCH
REDLLYRLNVITLHLPPLRERAEDILTLADRFLARFVKEYARPARGFSDEAREALLGYRW
HHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PGNIRELRNVVERASIICPQERVEISHLGMAEQPANNAPRVGAALSLDELEKAHIGAVLA
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TAGTLDQAAKTLGIDASTLYRKRKQYNL
HHCCHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MESATEHQGRILLVDDESAILRTFRYCLEDEGYTVATANSAAQADALLQRQVFDLCFLDL
CCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHE
RLGEDNGLDVLAQMRIQAPWMRVVIVTAHSAVDTAVDAIQAGAADYLVKPCSPDQLRLAT
EECCCCCHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHHCCCHHHEECCCCCCCEEHHH
AKQLEVRQLSARLEALEGEIRKPKDGLDSHSPAMKVVLETARQVAGTDANILILGESGTG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
KGELARAIHGWSKREKKSCVTINCPSLTAELMESELFGHSRGAFTGASESTLGRVNQADG
HHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCC
GTLFLDEIGDFPLTLQPKLLRFIQDKEYERVGDPVTRRADVRILAATNLNLEDMVRDGRF
CEEEHHCCCCCCCEECHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCHHHHHHCCCH
REDLLYRLNVITLHLPPLRERAEDILTLADRFLARFVKEYARPARGFSDEAREALLGYRW
HHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCC
PGNIRELRNVVERASIICPQERVEISHLGMAEQPANNAPRVGAALSLDELEKAHIGAVLA
CCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TAGTLDQAAKTLGIDASTLYRKRKQYNL
HHCCHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]