Click here to switch to the map view.

The map label for this gene is betC [H]

Identifier: 77456254

GI number: 77456254

Start: 28518

End: 30050

Strand: Reverse

Name: betC [H]

Synonym: Pfl01_0026

Alternate gene names: 77456254

Gene position: 30050-28518 (Counterclockwise)

Preceding gene: 77456256

Following gene: 77456253

Centisome position: 0.47

GC content: 59.75

Gene sequence:

>1533_bases
ATGGAATGCCGCGATCACATGAAGCGCAAGAACATTCTTTTCATCATGGCCGATCAAATGGCCGCGCCAATGTTGCCGTT
CTACGGCCCGTCGCCGATCAAACTGCCGAATCTCAGCCGCCTCGCCGAACAAGGCGTGGTGTTCGATGCCGCGTACTGCA
ACAGCCCGCTGTGCGCACCGTCGCGTTTTACCTTGGTCAGCGGGCAGTTGCCGAGCAAGATCGGCGCCTACGACAACGCC
GCCGATTTCCCCGCCGACATTCCCACCTACGCCCATTACCTGCGCCGCCTCGGTTACCGCACCGCGCTCTCCGGCAAGAT
GCACTTCTGCGGCCCCGATCAACTGCACGGTTACGAAGAGCGCCTGACCAGTGATATCTACCCGGCCGACTACGGCTGGG
CGGTGAACTGGGACGAGCCCGATGTGCGGCCGAGCTGGTATCACAACATGTCTTCGGTGTTGCAGGCCGGGCCGTGCGTG
CGCACCAACCAGCTCGACTTCGATGAAGAGGTGGTGTTCAAGGCTCAGCAATATCTGTTTGACCATATTCGCGAGGACGG
CGACCAGCCGTTCTGCCTGACCGTGTCGATGACTCACCCGCACGATCCGTACACGATTCCCAAGGCATTCTGGGATTTGT
ACGACGATGCGGATATACCGCTTCCAACGACGCCGGATCAGCATTCACTCGATCCGCATTCCCAGCGTTTGCTCAAGGTC
TACGACCTGTGGGACAAGCCGCTGCCTGTGGATAAGATTCGCGACGCGCGCCGTGCCTACTTCGGTGCTTGCAGTTATAT
CGACGCCAACGTCGGCAAACTTCTGCAAACCCTCGAAGATTGTGGGCTGATGGATGACACCGTCATCGTGTTTTCCGGTG
ACCATGGCGACATGCTCGGCGAGAAGGGCCTCTGGTACAAAATGCACTGGTTCGAAATGGCCGCGCGGGTTCCCCTGTTG
ATAAGTGCACCCGGTCAGTTCAAATCGGGCCGTGTCAGCGCTGCCGTCTCCACCGCCGACCTGTTGCCGACCTTCGTCGA
GCTGGCGGGCGGCAGCCTGGAACCGAATCTGCCGCTGGACGGCCGCTCGTTGGTTCCGCACCTGAACGGGCAGGGCGGTC
ACGACGAAGTGTTCGGCGAATACATGGCCGAAGGCACCGTCAGCCCGCTGATGATGATCCGGCGTGGCGCGTACAAATTT
ATCTACAGCGAAACCGACCCTTGCCTACTCTTCGATGTGGATAACGATCCACGCGAGCAGGAAGAACTCAGCCAATCGCC
ACAACATCGCCAACTGTTCGACGATTTTCTCGCCGAAGCGCGGGCCAAGTGGGACATCCCGGCCATCCACCGCAAAGTCC
TAGAAAGCCAGCGCCGTCGGCGTTTCGTCGCCGAGGCGCTGACGATCGGCAAACTGAAGAGCTGGGATCACCAGCCGCTG
GTGGACGCCAGTCAGCAATACATGCGCAACCACATCGACCTCGATGACCTGGAGCGCAAGGCCCGTTATCCACAACCCTG
CCAAAACCAATAA

Upstream 100 bases:

>100_bases
ACATAAGCTGTGCTTATCCTAGTCATTGTCCGGCGCGGGCTTTACCGGATATCGCGGGGAATCCATGCTCGATCGCAGCA
ATGTCGCATAAATATTCACT

Downstream 100 bases:

>100_bases
CGTTAAGGGGAAGTCCATGGTCAAGTTATCCACAGTCGTGACGGTCAGTCTGCTGGCACTGGGCAGCGCATCCGCGTTCG
CCGAGAGCTGCGACACGGTG

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MECRDHMKRKNILFIMADQMAAPMLPFYGPSPIKLPNLSRLAEQGVVFDAAYCNSPLCAPSRFTLVSGQLPSKIGAYDNA
ADFPADIPTYAHYLRRLGYRTALSGKMHFCGPDQLHGYEERLTSDIYPADYGWAVNWDEPDVRPSWYHNMSSVLQAGPCV
RTNQLDFDEEVVFKAQQYLFDHIREDGDQPFCLTVSMTHPHDPYTIPKAFWDLYDDADIPLPTTPDQHSLDPHSQRLLKV
YDLWDKPLPVDKIRDARRAYFGACSYIDANVGKLLQTLEDCGLMDDTVIVFSGDHGDMLGEKGLWYKMHWFEMAARVPLL
ISAPGQFKSGRVSAAVSTADLLPTFVELAGGSLEPNLPLDGRSLVPHLNGQGGHDEVFGEYMAEGTVSPLMMIRRGAYKF
IYSETDPCLLFDVDNDPREQEELSQSPQHRQLFDDFLAEARAKWDIPAIHRKVLESQRRRRFVAEALTIGKLKSWDHQPL
VDASQQYMRNHIDLDDLERKARYPQPCQNQ

Sequences:

>Translated_510_residues
MECRDHMKRKNILFIMADQMAAPMLPFYGPSPIKLPNLSRLAEQGVVFDAAYCNSPLCAPSRFTLVSGQLPSKIGAYDNA
ADFPADIPTYAHYLRRLGYRTALSGKMHFCGPDQLHGYEERLTSDIYPADYGWAVNWDEPDVRPSWYHNMSSVLQAGPCV
RTNQLDFDEEVVFKAQQYLFDHIREDGDQPFCLTVSMTHPHDPYTIPKAFWDLYDDADIPLPTTPDQHSLDPHSQRLLKV
YDLWDKPLPVDKIRDARRAYFGACSYIDANVGKLLQTLEDCGLMDDTVIVFSGDHGDMLGEKGLWYKMHWFEMAARVPLL
ISAPGQFKSGRVSAAVSTADLLPTFVELAGGSLEPNLPLDGRSLVPHLNGQGGHDEVFGEYMAEGTVSPLMMIRRGAYKF
IYSETDPCLLFDVDNDPREQEELSQSPQHRQLFDDFLAEARAKWDIPAIHRKVLESQRRRRFVAEALTIGKLKSWDHQPL
VDASQQYMRNHIDLDDLERKARYPQPCQNQ
>Mature_510_residues
MECRDHMKRKNILFIMADQMAAPMLPFYGPSPIKLPNLSRLAEQGVVFDAAYCNSPLCAPSRFTLVSGQLPSKIGAYDNA
ADFPADIPTYAHYLRRLGYRTALSGKMHFCGPDQLHGYEERLTSDIYPADYGWAVNWDEPDVRPSWYHNMSSVLQAGPCV
RTNQLDFDEEVVFKAQQYLFDHIREDGDQPFCLTVSMTHPHDPYTIPKAFWDLYDDADIPLPTTPDQHSLDPHSQRLLKV
YDLWDKPLPVDKIRDARRAYFGACSYIDANVGKLLQTLEDCGLMDDTVIVFSGDHGDMLGEKGLWYKMHWFEMAARVPLL
ISAPGQFKSGRVSAAVSTADLLPTFVELAGGSLEPNLPLDGRSLVPHLNGQGGHDEVFGEYMAEGTVSPLMMIRRGAYKF
IYSETDPCLLFDVDNDPREQEELSQSPQHRQLFDDFLAEARAKWDIPAIHRKVLESQRRRRFVAEALTIGKLKSWDHQPL
VDASQQYMRNHIDLDDLERKARYPQPCQNQ

Specific function: Converts choline-O-sulfate into choline [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4557659, Length=420, Percent_Identity=28.3333333333333, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI39930577, Length=450, Percent_Identity=26, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI5360208, Length=317, Percent_Identity=28.391167192429, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI31742482, Length=436, Percent_Identity=25.2293577981651, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI146229331, Length=474, Percent_Identity=25.9493670886076, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI146229329, Length=474, Percent_Identity=25.9493670886076, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI6005990, Length=474, Percent_Identity=25.9493670886076, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI146229324, Length=474, Percent_Identity=25.9493670886076, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI262118210, Length=343, Percent_Identity=27.9883381924198, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI4504061, Length=393, Percent_Identity=23.4096692111959, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI53831991, Length=113, Percent_Identity=35.3982300884956, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI146229327, Length=202, Percent_Identity=30.1980198019802, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1790112, Length=430, Percent_Identity=27.6744186046512, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17568795, Length=346, Percent_Identity=24.8554913294798, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24656835, Length=409, Percent_Identity=26.8948655256724, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24647401, Length=379, Percent_Identity=26.9129287598945, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666175, Length=392, Percent_Identity=25.5102040816327, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR017785
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.6 [H]

Molecular weight: Translated: 58034; Mature: 58034

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECRDHMKRKNILFIMADQMAAPMLPFYGPSPIKLPNLSRLAEQGVVFDAAYCNSPLCAP
CCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEHHHCCCCCCCC
SRFTLVSGQLPSKIGAYDNAADFPADIPTYAHYLRRLGYRTALSGKMHFCGPDQLHGYEE
CCEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCEECCCCHHHCCHHH
RLTSDIYPADYGWAVNWDEPDVRPSWYHNMSSVLQAGPCVRTNQLDFDEEVVFKAQQYLF
HHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
DHIREDGDQPFCLTVSMTHPHDPYTIPKAFWDLYDDADIPLPTTPDQHSLDPHSQRLLKV
HHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
YDLWDKPLPVDKIRDARRAYFGACSYIDANVGKLLQTLEDCGLMDDTVIVFSGDHGDMLG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
EKGLWYKMHWFEMAARVPLLISAPGQFKSGRVSAAVSTADLLPTFVELAGGSLEPNLPLD
CCCCEEEHHHHHHHHCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRSLVPHLNGQGGHDEVFGEYMAEGTVSPLMMIRRGAYKFIYSETDPCLLFDVDNDPREQ
CCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCEEEEECCCCCHHH
EELSQSPQHRQLFDDFLAEARAKWDIPAIHRKVLESQRRRRFVAEALTIGKLKSWDHQPL
HHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VDASQQYMRNHIDLDDLERKARYPQPCQNQ
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MECRDHMKRKNILFIMADQMAAPMLPFYGPSPIKLPNLSRLAEQGVVFDAAYCNSPLCAP
CCCHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEEHHHCCCCCCCC
SRFTLVSGQLPSKIGAYDNAADFPADIPTYAHYLRRLGYRTALSGKMHFCGPDQLHGYEE
CCEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCEECCCCHHHCCHHH
RLTSDIYPADYGWAVNWDEPDVRPSWYHNMSSVLQAGPCVRTNQLDFDEEVVFKAQQYLF
HHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
DHIREDGDQPFCLTVSMTHPHDPYTIPKAFWDLYDDADIPLPTTPDQHSLDPHSQRLLKV
HHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
YDLWDKPLPVDKIRDARRAYFGACSYIDANVGKLLQTLEDCGLMDDTVIVFSGDHGDMLG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
EKGLWYKMHWFEMAARVPLLISAPGQFKSGRVSAAVSTADLLPTFVELAGGSLEPNLPLD
CCCCEEEHHHHHHHHCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRSLVPHLNGQGGHDEVFGEYMAEGTVSPLMMIRRGAYKFIYSETDPCLLFDVDNDPREQ
CCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCEEEEECCCCCHHH
EELSQSPQHRQLFDDFLAEARAKWDIPAIHRKVLESQRRRRFVAEALTIGKLKSWDHQPL
HHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
VDASQQYMRNHIDLDDLERKARYPQPCQNQ
HHHHHHHHHHCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141699; 11481430; 9736747 [H]