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The map label for this gene is aroE [H]

Identifier: 77456251

GI number: 77456251

Start: 25085

End: 25906

Strand: Direct

Name: aroE [H]

Synonym: Pfl01_0023

Alternate gene names: 77456251

Gene position: 25085-25906 (Clockwise)

Preceding gene: 77456250

Following gene: 77456255

Centisome position: 0.39

GC content: 64.11

Gene sequence:

>822_bases
ATGGATCGTTACGTCGTTTTCGGTAACCCGATCGGCCACAGCAAGTCGCCGATGATTCACAAACTGTTCGCCGAACAGAC
CGGGCAGAGCCTCGACTACAGCACCCTGCTGGCGCCGCTCGACGATTTTTCCGGCTGCGCCACGGCGTTTTTCCAGGAAG
GTCGCGGCGCCAACGTGACCGTGCCGTTCAAGGAAGATGCTTATCGCCTGGCCAACAGCCTGACCGCCCGCGCCGAACGC
GCGGGTGCGGTGAACACGCTGAGCAAACTGGCTGACGGCAGCCTGCTCGGCGATAACACCGACGGCGCCGGGCTGGTGCG
CGATCTGACGGTCAATGGCGGGTTCAGCCTCACCGGCAAACGCATTCTGCTACTCGGCGCCGGTGGCGCGGTGCGCGGTG
CACTGGAGCCGTTGCTGGCGGAGAAACCGGCCTCGGTGATCATCGCCAACCGCACAGTGGACAAGGCCGAGCTGCTGGCT
GAACTGTTTTGTGATCTGGGGCCGGTGTCGGCCAGTGGTTACGACTGGTTGCGTGAACCGGTGGACGTGATCATCAACGC
CACCTCCGCCAGCCTCACCGGCGATGTGCCGCCGATTGCAGAAAGCCTGATCGAACCCGGCAAGACCCTGTGCTACGACA
TGATGTACGGCAAGGAACCGACCGCGTTCTGCCGCTGGGCCAGCGAGCATGGCGCGGGCGTGGTGATGGATGGCTTGGGC
ATGCTGGCGGAACAGGCGGCGGAAGCCTTCTTCCTGTGGCGCGGTGTGCGTCCCGACACTGCGCCGGTTCTGGCGGAGTT
GCGTCGACAACTGACGCTGTAA

Upstream 100 bases:

>100_bases
GGCCTACGACTGGAAAGCCGAACCGGGCAGCGAAGAAGCGCGCCTGACCGAGTACTTCCTGCAAGATCGCGACTGGCTAG
CCCAGGCCTGAGGACTTCTC

Downstream 100 bases:

>100_bases
GGCGCTTTAGTCTTCGAAGCGGATCGGGCATTTCTCCGGCCCTTCGAGTTTGCGCAACTCCTCCACCACCTGCGGTCGCG
CCTGACGCAAGGTCAGGCTG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MDRYVVFGNPIGHSKSPMIHKLFAEQTGQSLDYSTLLAPLDDFSGCATAFFQEGRGANVTVPFKEDAYRLANSLTARAER
AGAVNTLSKLADGSLLGDNTDGAGLVRDLTVNGGFSLTGKRILLLGAGGAVRGALEPLLAEKPASVIIANRTVDKAELLA
ELFCDLGPVSASGYDWLREPVDVIINATSASLTGDVPPIAESLIEPGKTLCYDMMYGKEPTAFCRWASEHGAGVVMDGLG
MLAEQAAEAFFLWRGVRPDTAPVLAELRRQLTL

Sequences:

>Translated_273_residues
MDRYVVFGNPIGHSKSPMIHKLFAEQTGQSLDYSTLLAPLDDFSGCATAFFQEGRGANVTVPFKEDAYRLANSLTARAER
AGAVNTLSKLADGSLLGDNTDGAGLVRDLTVNGGFSLTGKRILLLGAGGAVRGALEPLLAEKPASVIIANRTVDKAELLA
ELFCDLGPVSASGYDWLREPVDVIINATSASLTGDVPPIAESLIEPGKTLCYDMMYGKEPTAFCRWASEHGAGVVMDGLG
MLAEQAAEAFFLWRGVRPDTAPVLAELRRQLTL
>Mature_273_residues
MDRYVVFGNPIGHSKSPMIHKLFAEQTGQSLDYSTLLAPLDDFSGCATAFFQEGRGANVTVPFKEDAYRLANSLTARAER
AGAVNTLSKLADGSLLGDNTDGAGLVRDLTVNGGFSLTGKRILLLGAGGAVRGALEPLLAEKPASVIIANRTVDKAELLA
ELFCDLGPVSASGYDWLREPVDVIINATSASLTGDVPPIAESLIEPGKTLCYDMMYGKEPTAFCRWASEHGAGVVMDGLG
MLAEQAAEAFFLWRGVRPDTAPVLAELRRQLTL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=274, Percent_Identity=53.6496350364963, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=31.3653136531365, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=272, Percent_Identity=28.6764705882353, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29006; Mature: 29006

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRYVVFGNPIGHSKSPMIHKLFAEQTGQSLDYSTLLAPLDDFSGCATAFFQEGRGANVT
CCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCEEE
VPFKEDAYRLANSLTARAERAGAVNTLSKLADGSLLGDNTDGAGLVRDLTVNGGFSLTGK
ECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCCCEEEEEEECCCEEECCC
RILLLGAGGAVRGALEPLLAEKPASVIIANRTVDKAELLAELFCDLGPVSASGYDWLREP
EEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
VDVIINATSASLTGDVPPIAESLIEPGKTLCYDMMYGKEPTAFCRWASEHGAGVVMDGLG
HHHEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEHHHH
MLAEQAAEAFFLWRGVRPDTAPVLAELRRQLTL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDRYVVFGNPIGHSKSPMIHKLFAEQTGQSLDYSTLLAPLDDFSGCATAFFQEGRGANVT
CCCEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCEEE
VPFKEDAYRLANSLTARAERAGAVNTLSKLADGSLLGDNTDGAGLVRDLTVNGGFSLTGK
ECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCCCCCEEEEEEECCCEEECCC
RILLLGAGGAVRGALEPLLAEKPASVIIANRTVDKAELLAELFCDLGPVSASGYDWLREP
EEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
VDVIINATSASLTGDVPPIAESLIEPGKTLCYDMMYGKEPTAFCRWASEHGAGVVMDGLG
HHHEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEHHHH
MLAEQAAEAFFLWRGVRPDTAPVLAELRRQLTL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA