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The map label for this gene is sasA [H]

Identifier: 77456234

GI number: 77456234

Start: 7716

End: 9257

Strand: Direct

Name: sasA [H]

Synonym: Pfl01_0006

Alternate gene names: 77456234

Gene position: 7716-9257 (Clockwise)

Preceding gene: 77456232

Following gene: 77456239

Centisome position: 0.12

GC content: 60.96

Gene sequence:

>1542_bases
ATGAATAACCAGCGCCGACACGAAAGCCGCGTACCCAGCCAGGTTCAGCGGTTGTTCCGGCAACTGGTGCGCGAGTGGGT
GTGGATAAGTCTAGTGCTGTTGCCGCTGACTGCACTGCTTTCCTGGCGTGCGCAGATCAATTTGCATGACCCGGTGCCGT
TGATGGGCGCAGGACTTTCGGTAGCCATGGTTGCGTGCGTACTTGGGTTGCTGCTGTGGCGCCCGCGACTGGCGTTATGG
CTGACATTGGGCGGGATTGCCTGCGTGCTGCTGACCAGTGCAGGCCTGGCTGAAACGCGGCGTTGGTGGTCACCCACGCC
TGCGGCGCTGGGCATGCTGTTCGGCTATCTGATCTGGAACTGGCGTCGCTTGAGTGTGGTGCTCACCTACTTCGGCTGGG
AGTTGGCGCGGCTGGACAGTGAACCGAAAGTCTTTCCCGAACGACGTCGGGCGCAGTTTCCCAGCGCCGACCGCTTGCAG
GGGCAGATCATGGCGCTTGAGCAAGCCATGAGCCGTACCCGCGATACTCGCCGATTCATTGCCGACGGGCTGGAATATCT
GCCGGTCGCAACGCTGATCAGCGATCCTCGAGGAGAGGTCCTGTTGGGCAATCGCAAGGCCCGGAACCTGTTCGATCACA
CTCTGGTGGGCGAGGATGTGCTCGATCAACTGGCGAGCCTGGGCTATCCGGAGTTGTCCACAGAGCCGCGCCCGCCACTA
TCCGAGCTGCCTCTGCTGGAGTTTCGTGACCACAAGGAACGTAGCCTGCGTCTGGAACGCGCCGCGTTGTTGCCAGTGGA
TGGCGACATACCGATTGGCTGGCTGCTGAGTCTCACTGACCTGAGCGCCGAACGCGCCGCCGAGGAACAGCGTGGCGTGC
TGTTGCGCTTTCTGTCCCACGACCTGCGCGCTCCTCATTCGGCGATTCTTGCCCTGCTCGAGGTACACCGGCATCAGACG
GGAACGGATTCACCGCTGTTCGAACAGATTGAGCGCCAGGTACGTCGGGCGCTGGAACTCACCGACGGCTTCGTTCTGTT
GGCCCGGGCCGAGTCCGAGGCCTATCAGTTTCAACCGAGCCTGTTCGGGATGCTGGTCATGGACGTGCTGGATCAGGCGT
TGCCGATCGCTCAGCAAAAGCTCATCGAGCTCTCGAGCGACATGGACGAACAATCACACGAGCGCCTGATCATGGCCGAT
CAGGGCTTGCTGACCCGCGCGCTGTTCAACCTGCTGGAAAATGCAATCAAGTACAGCCCGGCCGGTTCAACCGTCGATCT
GCGTGTCAGCTGCCACGACGACTGGCTGCGTTGTGAACTGATTGATCAAGGCAAAGGCATCGCTGCAGAGGAACTGCCCG
ATCTGTTCAGCCAGTACCGGCGCTTTTCTTCTGCACAAGGTATCGACGGCGTGGGCCTGGGGTTGTCGATGGTCAAAGCC
GTGGTCGATCACCATGGTGGCCGGATCGAATGCGTGAGCGTGGTTGATCGAGGCACGACGTTCCGTCTGGAGCTGCCGCT
GATCGCTGAAGAGCAGGCATAA

Upstream 100 bases:

>100_bases
GTAAGCGGCACGCCTTGGAGTGAGCCGCTATGATTCTTCGGGTCTACGTCCTCAGACCGGCCGCCTATGAAACCATTCAA
CCTGCCCTGCCCTGTTTCCC

Downstream 100 bases:

>100_bases
AAAAACCGGCTATATCAGCCGGTTTCCTTACTTCCGAAAAAAACTTATGCACCTTTTACGGTGTTTTATCAGATTCGGAA
ATATATAAATAAATCAGTCA

Product: periplasmic sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MNNQRRHESRVPSQVQRLFRQLVREWVWISLVLLPLTALLSWRAQINLHDPVPLMGAGLSVAMVACVLGLLLWRPRLALW
LTLGGIACVLLTSAGLAETRRWWSPTPAALGMLFGYLIWNWRRLSVVLTYFGWELARLDSEPKVFPERRRAQFPSADRLQ
GQIMALEQAMSRTRDTRRFIADGLEYLPVATLISDPRGEVLLGNRKARNLFDHTLVGEDVLDQLASLGYPELSTEPRPPL
SELPLLEFRDHKERSLRLERAALLPVDGDIPIGWLLSLTDLSAERAAEEQRGVLLRFLSHDLRAPHSAILALLEVHRHQT
GTDSPLFEQIERQVRRALELTDGFVLLARAESEAYQFQPSLFGMLVMDVLDQALPIAQQKLIELSSDMDEQSHERLIMAD
QGLLTRALFNLLENAIKYSPAGSTVDLRVSCHDDWLRCELIDQGKGIAAEELPDLFSQYRRFSSAQGIDGVGLGLSMVKA
VVDHHGGRIECVSVVDRGTTFRLELPLIAEEQA

Sequences:

>Translated_513_residues
MNNQRRHESRVPSQVQRLFRQLVREWVWISLVLLPLTALLSWRAQINLHDPVPLMGAGLSVAMVACVLGLLLWRPRLALW
LTLGGIACVLLTSAGLAETRRWWSPTPAALGMLFGYLIWNWRRLSVVLTYFGWELARLDSEPKVFPERRRAQFPSADRLQ
GQIMALEQAMSRTRDTRRFIADGLEYLPVATLISDPRGEVLLGNRKARNLFDHTLVGEDVLDQLASLGYPELSTEPRPPL
SELPLLEFRDHKERSLRLERAALLPVDGDIPIGWLLSLTDLSAERAAEEQRGVLLRFLSHDLRAPHSAILALLEVHRHQT
GTDSPLFEQIERQVRRALELTDGFVLLARAESEAYQFQPSLFGMLVMDVLDQALPIAQQKLIELSSDMDEQSHERLIMAD
QGLLTRALFNLLENAIKYSPAGSTVDLRVSCHDDWLRCELIDQGKGIAAEELPDLFSQYRRFSSAQGIDGVGLGLSMVKA
VVDHHGGRIECVSVVDRGTTFRLELPLIAEEQA
>Mature_513_residues
MNNQRRHESRVPSQVQRLFRQLVREWVWISLVLLPLTALLSWRAQINLHDPVPLMGAGLSVAMVACVLGLLLWRPRLALW
LTLGGIACVLLTSAGLAETRRWWSPTPAALGMLFGYLIWNWRRLSVVLTYFGWELARLDSEPKVFPERRRAQFPSADRLQ
GQIMALEQAMSRTRDTRRFIADGLEYLPVATLISDPRGEVLLGNRKARNLFDHTLVGEDVLDQLASLGYPELSTEPRPPL
SELPLLEFRDHKERSLRLERAALLPVDGDIPIGWLLSLTDLSAERAAEEQRGVLLRFLSHDLRAPHSAILALLEVHRHQT
GTDSPLFEQIERQVRRALELTDGFVLLARAESEAYQFQPSLFGMLVMDVLDQALPIAQQKLIELSSDMDEQSHERLIMAD
QGLLTRALFNLLENAIKYSPAGSTVDLRVSCHDDWLRCELIDQGKGIAAEELPDLFSQYRRFSSAQGIDGVGLGLSMVKA
VVDHHGGRIECVSVVDRGTTFRLELPLIAEEQA

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=29.7413793103448, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786600, Length=418, Percent_Identity=23.2057416267943, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=217, Percent_Identity=29.0322580645161, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790436, Length=111, Percent_Identity=36.9369369369369, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=219, Percent_Identity=29.6803652968037, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=219, Percent_Identity=27.3972602739726, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=26.3598326359833, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=373, Percent_Identity=26.0053619302949, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 57851; Mature: 57851

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNQRRHESRVPSQVQRLFRQLVREWVWISLVLLPLTALLSWRAQINLHDPVPLMGAGLS
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHH
VAMVACVLGLLLWRPRLALWLTLGGIACVLLTSAGLAETRRWWSPTPAALGMLFGYLIWN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHH
WRRLSVVLTYFGWELARLDSEPKVFPERRRAQFPSADRLQGQIMALEQAMSRTRDTRRFI
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADGLEYLPVATLISDPRGEVLLGNRKARNLFDHTLVGEDVLDQLASLGYPELSTEPRPPL
HCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCH
SELPLLEFRDHKERSLRLERAALLPVDGDIPIGWLLSLTDLSAERAAEEQRGVLLRFLSH
HHCCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRAPHSAILALLEVHRHQTGTDSPLFEQIERQVRRALELTDGFVLLARAESEAYQFQPS
HHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCHH
LFGMLVMDVLDQALPIAQQKLIELSSDMDEQSHERLIMADQGLLTRALFNLLENAIKYSP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCHHHHHHHHHHHHHHHCCC
AGSTVDLRVSCHDDWLRCELIDQGKGIAAEELPDLFSQYRRFSSAQGIDGVGLGLSMVKA
CCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VVDHHGGRIECVSVVDRGTTFRLELPLIAEEQA
HHHCCCCCEEEEEEECCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MNNQRRHESRVPSQVQRLFRQLVREWVWISLVLLPLTALLSWRAQINLHDPVPLMGAGLS
CCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHH
VAMVACVLGLLLWRPRLALWLTLGGIACVLLTSAGLAETRRWWSPTPAALGMLFGYLIWN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHH
WRRLSVVLTYFGWELARLDSEPKVFPERRRAQFPSADRLQGQIMALEQAMSRTRDTRRFI
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADGLEYLPVATLISDPRGEVLLGNRKARNLFDHTLVGEDVLDQLASLGYPELSTEPRPPL
HCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCH
SELPLLEFRDHKERSLRLERAALLPVDGDIPIGWLLSLTDLSAERAAEEQRGVLLRFLSH
HHCCCHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRAPHSAILALLEVHRHQTGTDSPLFEQIERQVRRALELTDGFVLLARAESEAYQFQPS
HHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCHH
LFGMLVMDVLDQALPIAQQKLIELSSDMDEQSHERLIMADQGLLTRALFNLLENAIKYSP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCHHHHHHHHHHHHHHHCCC
AGSTVDLRVSCHDDWLRCELIDQGKGIAAEELPDLFSQYRRFSSAQGIDGVGLGLSMVKA
CCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
VVDHHGGRIECVSVVDRGTTFRLELPLIAEEQA
HHHCCCCCEEEEEEECCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA