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The map label for this gene is ycbL [H]

Identifier: 77456233

GI number: 77456233

Start: 6835

End: 7551

Strand: Reverse

Name: ycbL [H]

Synonym: Pfl01_0005

Alternate gene names: 77456233

Gene position: 7551-6835 (Counterclockwise)

Preceding gene: 77456235

Following gene: NA

Centisome position: 0.12

GC content: 61.23

Gene sequence:

>717_bases
ATGCGCGTTGCGATACTGGACGATGAACCCGCCGAACTGCGCCGGGTCGAGCAGACCCTGCAACAAATGGCCGAGGCCGG
AGGACAGCCCTGGTCACTGCACAGCTTCGAAAGCGGTGAAGACCTGCTGCGTCAGTTGCGTCGAGAAACCTTCGACCTGC
TGATCCTCGACTGGCAATTGCCCGACCTGACCGGCCTGGCGCTGCTGCGCTGGACCCGCGAACACATGGAAGCGCCGCCA
GCGGCCATCATGCTGACCAGCCGCGATGGTGAGAGCGATATCGTCCAGGCCCTGAATGCCGGGGCCGACGATTACGTCAG
CAAGCCGTTTCGGCCCAATGAATTGAAAGCCCGGGTTGCAGCGGTACTGCGTCGGCACAGCCTGCAACGTAACGCCGCGG
CCGACGTCCTGCGTTTCAATGACCTGGTGTTCGACGACGCCGAGCTGACTGTCACCCGCGACGGGAAACCGATTGTCATG
ACCGAGCGCGAGTATCGACTCGCTCACTGCCTGTTCAGCAATCTTGGCCGACCGCTTTCACGGGATTACCTGTACGAACG
ATTCTGGCCCCACGAAGAAATGTCCACGTCGCGACCGCTGGACACGCATATCTATCGCCTGCGCAACAAGCTCGGGCTGA
CGGCGGATCGGGGTTGGCAGTTACTGACGATTTATGGGTATGGGTATCGTTTGGAGAGTGTGGCGGCAGGCGAGTGA

Upstream 100 bases:

>100_bases
GAATCATAGCGGCTCACTCCAAGGCGTGCCGCTTACTTTCACTGCATGGAGTGAGCCGATCCGGTCGGCACACCACCCGA
GCGACAAGGAACCACCGCGT

Downstream 100 bases:

>100_bases
ATCGCAGGCAATAAAAAAGGCCAACGCTGGTGCGTTGGCCTTTTCGTTGGTGCTGACCAGGATCAGAAATCCAGGTTGGA
CACCGCCAGAGCGTTGCTCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRVAILDDEPAELRRVEQTLQQMAEAGGQPWSLHSFESGEDLLRQLRRETFDLLILDWQLPDLTGLALLRWTREHMEAPP
AAIMLTSRDGESDIVQALNAGADDYVSKPFRPNELKARVAAVLRRHSLQRNAAADVLRFNDLVFDDAELTVTRDGKPIVM
TEREYRLAHCLFSNLGRPLSRDYLYERFWPHEEMSTSRPLDTHIYRLRNKLGLTADRGWQLLTIYGYGYRLESVAAGE

Sequences:

>Translated_238_residues
MRVAILDDEPAELRRVEQTLQQMAEAGGQPWSLHSFESGEDLLRQLRRETFDLLILDWQLPDLTGLALLRWTREHMEAPP
AAIMLTSRDGESDIVQALNAGADDYVSKPFRPNELKARVAAVLRRHSLQRNAAADVLRFNDLVFDDAELTVTRDGKPIVM
TEREYRLAHCLFSNLGRPLSRDYLYERFWPHEEMSTSRPLDTHIYRLRNKLGLTADRGWQLLTIYGYGYRLESVAAGE
>Mature_238_residues
MRVAILDDEPAELRRVEQTLQQMAEAGGQPWSLHSFESGEDLLRQLRRETFDLLILDWQLPDLTGLALLRWTREHMEAPP
AAIMLTSRDGESDIVQALNAGADDYVSKPFRPNELKARVAAVLRRHSLQRNAAADVLRFNDLVFDDAELTVTRDGKPIVM
TEREYRLAHCLFSNLGRPLSRDYLYERFWPHEEMSTSRPLDTHIYRLRNKLGLTADRGWQLLTIYGYGYRLESVAAGE

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=34.1880341880342, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=32.4675324675325, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=33.0508474576271, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786911, Length=180, Percent_Identity=37.2222222222222, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789809, Length=205, Percent_Identity=33.1707317073171, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=31.6017316017316, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1790860, Length=216, Percent_Identity=32.8703703703704, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787229, Length=236, Percent_Identity=33.0508474576271, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082012, Length=234, Percent_Identity=31.6239316239316, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=31.7596566523605, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=29.7872340425532, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786784, Length=188, Percent_Identity=32.9787234042553, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI2367329, Length=181, Percent_Identity=32.0441988950276, Blast_Score=84, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27409; Mature: 27409

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAILDDEPAELRRVEQTLQQMAEAGGQPWSLHSFESGEDLLRQLRRETFDLLILDWQL
CEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECC
PDLTGLALLRWTREHMEAPPAAIMLTSRDGESDIVQALNAGADDYVSKPFRPNELKARVA
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
AVLRRHSLQRNAAADVLRFNDLVFDDAELTVTRDGKPIVMTEREYRLAHCLFSNLGRPLS
HHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEEECHHHHHHHHHHHHCCCCHH
RDYLYERFWPHEEMSTSRPLDTHIYRLRNKLGLTADRGWQLLTIYGYGYRLESVAAGE
HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEECCCCCCC
>Mature Secondary Structure
MRVAILDDEPAELRRVEQTLQQMAEAGGQPWSLHSFESGEDLLRQLRRETFDLLILDWQL
CEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECC
PDLTGLALLRWTREHMEAPPAAIMLTSRDGESDIVQALNAGADDYVSKPFRPNELKARVA
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHH
AVLRRHSLQRNAAADVLRFNDLVFDDAELTVTRDGKPIVMTEREYRLAHCLFSNLGRPLS
HHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCEEEEECHHHHHHHHHHHHCCCCHH
RDYLYERFWPHEEMSTSRPLDTHIYRLRNKLGLTADRGWQLLTIYGYGYRLESVAAGE
HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]