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The map label for this gene is plsC [C]

Identifier: 77456235

GI number: 77456235

Start: 9415

End: 10239

Strand: Reverse

Name: plsC [C]

Synonym: Pfl01_0007

Alternate gene names: 77456235

Gene position: 10239-9415 (Counterclockwise)

Preceding gene: 77456236

Following gene: 77456233

Centisome position: 0.16

GC content: 59.39

Gene sequence:

>825_bases
GTGCGCTTGAACAGTCGGGCATTGCCCGTAACGGTAAACGTCGCCATGTCGATACTGCAGGCCATCAGAATCTTCCTCTT
TTACCTGCTGCTGGGCACCACCGCTCTGCTGTGGTGCAGCCTGAGCTTTTTTATCGCGCCCTTTCTGTCGTTCAAGGCGC
GCTATCGTTTCATCAACGTGTACTGGTGCCGCTGCGCCTTGTGGTTGACCAAGGTGTTTCTCGGTATCCGTTACGAAGTC
AAAGGCGCGGAAAACGTGCCTGACCGGCCGTGCGTGATTCAATCGAACCACCAGAGCACGTGGGAGACGTTTTTTCTCTC
CGCTTATTTCTCGCCCTTGAGCCAGGTGCTCAAGCGCGAACTGCTGTACGTGCCGTTCTTCGGCTGGGCCATGGCCATGC
TGCGGCCGATCGCGATTGACCGCGACAACCCGAAAGCCGCCCTCAAGCAGGTGGCGGCGAAAGGTGACGAGCTGCTCAAG
GACGATGTCTGGGTGCTGATCTTCCCGGAAGGCACTCGCGTTCCCCACGGCACCATCGGCAAGTTCTCCCGCAGTGGCAG
CGCATTGGCGGTGAATGCAGCGCTTCCGGTACTGCCGATTGCACACAATGCCGGCAAGTTCTGGCCGAAAATCGGCTGGG
GCAAAAAGTCCGGTGTGATCACCGTGGTGATTGGTGAGCCTATGTACGCCGAGGGCAGTGGACCTCGCGCCATCGCCGAT
CTGAATGATCGGGTGCAGGCGTGGAACGAGAAGACACAACGGGAAATGGGCTCGCTGCCCCCGGCTCCTGAGGCACCGGC
TGCGAACGATCAGATCGCTGTCTGA

Upstream 100 bases:

>100_bases
CCGGTGGGCACCCTGATTTTTGACGATCTCGCGGCGATTGCCGCAGAACTTATCCACAACTAGAGTGCTTCTGAAGTTCC
TGACCAGGGATTGATCGGGA

Downstream 100 bases:

>100_bases
GATTTGTGGATAACCTGTGTACGGTTTGTTCGCAAAGCGCCGAATCATCAAACTAAGTGACTGATTTATTTATATATTTC
CGAATCTGATAAAACACCGT

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; Acyltransferase Family Protein; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; Acyltransferase Domain-Containing Protein; Scaffold Protein; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MRLNSRALPVTVNVAMSILQAIRIFLFYLLLGTTALLWCSLSFFIAPFLSFKARYRFINVYWCRCALWLTKVFLGIRYEV
KGAENVPDRPCVIQSNHQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLRPIAIDRDNPKAALKQVAAKGDELLK
DDVWVLIFPEGTRVPHGTIGKFSRSGSALAVNAALPVLPIAHNAGKFWPKIGWGKKSGVITVVIGEPMYAEGSGPRAIAD
LNDRVQAWNEKTQREMGSLPPAPEAPAANDQIAV

Sequences:

>Translated_274_residues
MRLNSRALPVTVNVAMSILQAIRIFLFYLLLGTTALLWCSLSFFIAPFLSFKARYRFINVYWCRCALWLTKVFLGIRYEV
KGAENVPDRPCVIQSNHQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLRPIAIDRDNPKAALKQVAAKGDELLK
DDVWVLIFPEGTRVPHGTIGKFSRSGSALAVNAALPVLPIAHNAGKFWPKIGWGKKSGVITVVIGEPMYAEGSGPRAIAD
LNDRVQAWNEKTQREMGSLPPAPEAPAANDQIAV
>Mature_274_residues
MRLNSRALPVTVNVAMSILQAIRIFLFYLLLGTTALLWCSLSFFIAPFLSFKARYRFINVYWCRCALWLTKVFLGIRYEV
KGAENVPDRPCVIQSNHQSTWETFFLSAYFSPLSQVLKRELLYVPFFGWAMAMLRPIAIDRDNPKAALKQVAAKGDELLK
DDVWVLIFPEGTRVPHGTIGKFSRSGSALAVNAALPVLPIAHNAGKFWPKIGWGKKSGVITVVIGEPMYAEGSGPRAIAD
LNDRVQAWNEKTQREMGSLPPAPEAPAANDQIAV

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5453718, Length=203, Percent_Identity=33.0049261083744, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI15100175, Length=203, Percent_Identity=33.0049261083744, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI6041665, Length=202, Percent_Identity=28.7128712871287, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564032, Length=242, Percent_Identity=26.0330578512397, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320151, Length=260, Percent_Identity=28.8461538461538, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641614, Length=196, Percent_Identity=27.5510204081633, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24641612, Length=196, Percent_Identity=27.5510204081633, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281364648, Length=187, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582856, Length=187, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582854, Length=187, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 30542; Mature: 30542

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNSRALPVTVNVAMSILQAIRIFLFYLLLGTTALLWCSLSFFIAPFLSFKARYRFINV
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWCRCALWLTKVFLGIRYEVKGAENVPDRPCVIQSNHQSTWETFFLSAYFSPLSQVLKRE
HHHHHHHHHHHHHHHCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LLYVPFFGWAMAMLRPIAIDRDNPKAALKQVAAKGDELLKDDVWVLIFPEGTRVPHGTIG
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCC
KFSRSGSALAVNAALPVLPIAHNAGKFWPKIGWGKKSGVITVVIGEPMYAEGSGPRAIAD
CCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCEEEHH
LNDRVQAWNEKTQREMGSLPPAPEAPAANDQIAV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLNSRALPVTVNVAMSILQAIRIFLFYLLLGTTALLWCSLSFFIAPFLSFKARYRFINV
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YWCRCALWLTKVFLGIRYEVKGAENVPDRPCVIQSNHQSTWETFFLSAYFSPLSQVLKRE
HHHHHHHHHHHHHHHCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LLYVPFFGWAMAMLRPIAIDRDNPKAALKQVAAKGDELLKDDVWVLIFPEGTRVPHGTIG
HHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCC
KFSRSGSALAVNAALPVLPIAHNAGKFWPKIGWGKKSGVITVVIGEPMYAEGSGPRAIAD
CCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCEEEHH
LNDRVQAWNEKTQREMGSLPPAPEAPAANDQIAV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA