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The map label for this gene is hpnA [H]

Identifier: 76819826

GI number: 76819826

Start: 1592432

End: 1593448

Strand: Direct

Name: hpnA [H]

Synonym: BURPS1710b_A1280

Alternate gene names: 76819826

Gene position: 1592432-1593448 (Clockwise)

Preceding gene: 76817279

Following gene: 76819824

Centisome position: 50.05

GC content: 71.09

Gene sequence:

>1017_bases
ATGAGGACCATGACTGACACACAACGCGATCTCGTTCTGGTGACCGGCGCATCCGGTTTTGTCGGCTCCGCCGTCGCGCG
CGCCGCGCGGCGGCAGGGCTATCGGGTGCGCGTGCTCGTGCGGCCGACGAGCCCGCGCACGAACGTCGCGGATCTCGACG
CCGAGATCGCCACCGGCGACATGCGCGACGAGGCATCGATGCGCGCCGCGCTGCGCGGCGTGCGCCATCTGCTGCACGTC
GCCGCCGACTACCGGCTGTGGGCGCCCGATCCGCTCGAGATCGAGCGCGCGAATCTCGAAGGCGCGGTCGCGACGATGCG
CGCGGCGCTCGCCGAGGGCGTCGAGCGGATCGTCTACACGAGCAGCGTCGCCACGCTGAAGGTAACGCCGTCGGGCGCCT
CGGCCGACGAATCGTCGCCGCTCGCCGCCGGGCAGGCGATCGGCGTATACAAGCGCAGCAAGGTGCTCGCCGAGCGCGCG
GTCGAGCGGATGATCGCCGAGGACGGGCTGCCCGCGGTGATCGTCAATCCGTCGACGCCGATCGGCCCGCGCGACGTGAA
GCCGACGCCGACCGGCCGGATCATCGTCGAGGCGGCGCTCGGCAAGATCCCGGCGTTCGTCGACACGGGGCTGAACCTCG
TGCACGTCGACGACGTCGCGCAGGGCCACCTGCTCGCGCTCGAGCGCGGGCGCGTCGGCGAGCGCTACATCCTCGGCGGC
GAGAACCTGCCGCTGCAGGCGATGCTCGCCGACATCGCGCAATCGACGGGACGCAAGCCGCCGACGATCGCGCTGCCGCG
CTGGCCGCTGTATCCGATCGCGCTCGGCGCGGAGGCGGTGGCGAAGCTGACGAAGCGCGAGCCGTTCGTGACGGTCGACG
GGCTCAGGATGTCGAAGAACAAGATGTATTTCACGTCCGCGAAAGCCGAGCGCGAGCTCGGCTACCGCGCGCGGCCGTAC
CGCGAAGGCATTCGCGACGCGCTCGACTGGTTCAGGCAGGCGGGCTATCTGCGCTGA

Upstream 100 bases:

>100_bases
CGCGAACGATGCTCGATGCAGCCCGCGCGCCGCGCATCCCGGGCGAGCACGTACAATCTCGCACGACGTACAACACGCCG
CGCCGCACGGCCGCGCGGCC

Downstream 100 bases:

>100_bases
GCGCCAACCGCGCGGGGCGTCCGGACGCGAGCGGGCGCAGACCGCGCGGGCGGGCCGGTTCGTTCGATGCGGCCCGCCCG
CGCGCACCGGCGCCGCCGGA

Product: dihydroflavonol-4-reductase family protein

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRTMTDTQRDLVLVTGASGFVGSAVARAARRQGYRVRVLVRPTSPRTNVADLDAEIATGDMRDEASMRAALRGVRHLLHV
AADYRLWAPDPLEIERANLEGAVATMRAALAEGVERIVYTSSVATLKVTPSGASADESSPLAAGQAIGVYKRSKVLAERA
VERMIAEDGLPAVIVNPSTPIGPRDVKPTPTGRIIVEAALGKIPAFVDTGLNLVHVDDVAQGHLLALERGRVGERYILGG
ENLPLQAMLADIAQSTGRKPPTIALPRWPLYPIALGAEAVAKLTKREPFVTVDGLRMSKNKMYFTSAKAERELGYRARPY
REGIRDALDWFRQAGYLR

Sequences:

>Translated_338_residues
MRTMTDTQRDLVLVTGASGFVGSAVARAARRQGYRVRVLVRPTSPRTNVADLDAEIATGDMRDEASMRAALRGVRHLLHV
AADYRLWAPDPLEIERANLEGAVATMRAALAEGVERIVYTSSVATLKVTPSGASADESSPLAAGQAIGVYKRSKVLAERA
VERMIAEDGLPAVIVNPSTPIGPRDVKPTPTGRIIVEAALGKIPAFVDTGLNLVHVDDVAQGHLLALERGRVGERYILGG
ENLPLQAMLADIAQSTGRKPPTIALPRWPLYPIALGAEAVAKLTKREPFVTVDGLRMSKNKMYFTSAKAERELGYRARPY
REGIRDALDWFRQAGYLR
>Mature_338_residues
MRTMTDTQRDLVLVTGASGFVGSAVARAARRQGYRVRVLVRPTSPRTNVADLDAEIATGDMRDEASMRAALRGVRHLLHV
AADYRLWAPDPLEIERANLEGAVATMRAALAEGVERIVYTSSVATLKVTPSGASADESSPLAAGQAIGVYKRSKVLAERA
VERMIAEDGLPAVIVNPSTPIGPRDVKPTPTGRIIVEAALGKIPAFVDTGLNLVHVDDVAQGHLLALERGRVGERYILGG
ENLPLQAMLADIAQSTGRKPPTIALPRWPLYPIALGAEAVAKLTKREPFVTVDGLRMSKNKMYFTSAKAERELGYRARPY
REGIRDALDWFRQAGYLR

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

Organism=Homo sapiens, GI116268111, Length=358, Percent_Identity=26.2569832402235, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI193211614, Length=336, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI8393516, Length=336, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI310132178, Length=359, Percent_Identity=25.6267409470752, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI310113012, Length=359, Percent_Identity=25.6267409470752, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI239745448, Length=359, Percent_Identity=25.6267409470752, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71987463, Length=334, Percent_Identity=27.8443113772455, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 36668; Mature: 36668

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTMTDTQRDLVLVTGASGFVGSAVARAARRQGYRVRVLVRPTSPRTNVADLDAEIATGD
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCHHCCCC
MRDEASMRAALRGVRHLLHVAADYRLWAPDPLEIERANLEGAVATMRAALAEGVERIVYT
CHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEE
SSVATLKVTPSGASADESSPLAAGQAIGVYKRSKVLAERAVERMIAEDGLPAVIVNPSTP
CCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
IGPRDVKPTPTGRIIVEAALGKIPAFVDTGLNLVHVDDVAQGHLLALERGRVGERYILGG
CCCCCCCCCCCCCEEEEEHHCCCCHHHHCCCCEEEECCCCCCCEEEEECCCCCCEEEECC
ENLPLQAMLADIAQSTGRKPPTIALPRWPLYPIALGAEAVAKLTKREPFVTVDGLRMSKN
CCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCHHHHHHHHCCCCEEEECCCEECCC
KMYFTSAKAERELGYRARPYREGIRDALDWFRQAGYLR
EEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRTMTDTQRDLVLVTGASGFVGSAVARAARRQGYRVRVLVRPTSPRTNVADLDAEIATGD
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCHHCCCC
MRDEASMRAALRGVRHLLHVAADYRLWAPDPLEIERANLEGAVATMRAALAEGVERIVYT
CHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEE
SSVATLKVTPSGASADESSPLAAGQAIGVYKRSKVLAERAVERMIAEDGLPAVIVNPSTP
CCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
IGPRDVKPTPTGRIIVEAALGKIPAFVDTGLNLVHVDDVAQGHLLALERGRVGERYILGG
CCCCCCCCCCCCCEEEEEHHCCCCHHHHCCCCEEEECCCCCCCEEEEECCCCCCEEEECC
ENLPLQAMLADIAQSTGRKPPTIALPRWPLYPIALGAEAVAKLTKREPFVTVDGLRMSKN
CCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCHHHHHHHHCCCCEEEECCCEECCC
KMYFTSAKAERELGYRARPYREGIRDALDWFRQAGYLR
EEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]