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The map label for this gene is apbE [H]

Identifier: 76819747

GI number: 76819747

Start: 679090

End: 680274

Strand: Direct

Name: apbE [H]

Synonym: BURPS1710b_A0494

Alternate gene names: 76819747

Gene position: 679090-680274 (Clockwise)

Preceding gene: 76819144

Following gene: 76818761

Centisome position: 21.34

GC content: 73.67

Gene sequence:

>1185_bases
ATGTCGAAGACGTCTATTGAATGGTCGCCCGGCGCGCGGCTGAATCGCTGCCGCGCAAGCGGCGCGACGATGGGCACGCG
CTACGGCGCGCAGTTCTACGCGCCGCCGACGGCCGACGCGAGGGCGATCGCGGCCGCCCTCGACGCGGCGGTGCGGGCGG
TCGACGCGCAGATGTCGAACTGGAAGGCCGATTCGGATCTGTCGCGGCTCAATCGCGCGACGCCCGGAAGCTGGACGCCG
ATCTGCGCGAACCTCGCCGCGGTGCTCGTGCGCGCGCGGGAAATCGGCCGCGAGACGGACAACGCGTTCAACATCGGCGT
CGGCACGCTCGTCGATCGATGGGGATTCGGGCCGGGCGCGGCCGCGAACCGACAAGCGGACAACGAATGGGCGGCGAATC
GACAGGCGGCCGGCCGACACACGGTTGATCGACGTACGGTTGATCGACACACGGCGGACCGACACACGGCGGACCGACAA
ACGAAGGACGGGCGCACGCCGGACCGCCAGCCGGCGCGCCCGGCCGACCCCGCGAACGGGTTGTCGGGCGCGATCGACGC
GCGCCGCCGCGCGTCGATCCTGCGCGGCCCCGTGCCGTCGCCGTGCCGCCCGATCGACGAACTGCTCGAAGTCGATGTCG
CGCGGGGCCGGGCGCGCCGGCTCGCGGACGTCGCCTTCGACCTGTGCGGGATCGCGAAGGGCTTCGGCGTGGACGAGCTT
GCGCGCGTGCTCGATCGCCACGGCATCGGCGCATGGCTCGTCGGCATCGACGGCGAGCTGCGCGCGCGCGGATGCAAGCC
GGACGGCTCGCCGTGGGCGATCGCGCTCGAAGCGCCCGACTACGGCCGGCGCGGCGCGATGGGCGCGATCGATCTCGTCG
ACGCGGCCGTCGCGACCTCCGGCGATTACCGGCATTGGGCCGACTTCGGCGGCGAACGCCTCTCGCATACGATGGACCCG
CGCGCCGGCGCGCCGCTGCGCGGCGACATCGCCTCGGTCACGGTCGTCGCGCCGACCTGCACCGACGCGGACGCGTACGC
CACCGCGTTGATGGTGCTCGGCGCGCAGGCGGGATGCGCGCACGCCGAACGCCACGGGCTCGACGCGCTGTTCGTCGTGC
GCGACGGCGACGCGCTGCGCACGATCGGCTGCGGCGCTTTCGCGGACGCGGGGCCGGCGGGCTGA

Upstream 100 bases:

>100_bases
TGCGGCGGCCGCGCGATGGCCGACGGCGTCGCGCGCGCGTGGGAGCGCATCCTGGCGGATTCCGGCTCGTCCGTCGCGCA
ATTGAAGCAGCAGGGGCGCT

Downstream 100 bases:

>100_bases
GCGCCGCGCGGCGCTTACACGTCGAACTTCACGCCCTGCGCGAGCGGCAATTCGCGGCTGTAGTTGATCGTGTTCGTCGC
GCGGCGCATGTAGCTCTTCC

Product: ApbE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MSKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSNWKADSDLSRLNRATPGSWTP
ICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGAAANRQADNEWAANRQAAGRHTVDRRTVDRHTADRHTADRQ
TKDGRTPDRQPARPADPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRARRLADVAFDLCGIAKGFGVDEL
ARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATSGDYRHWADFGGERLSHTMDP
RAGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADAGPAG

Sequences:

>Translated_394_residues
MSKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSNWKADSDLSRLNRATPGSWTP
ICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGAAANRQADNEWAANRQAAGRHTVDRRTVDRHTADRHTADRQ
TKDGRTPDRQPARPADPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRARRLADVAFDLCGIAKGFGVDEL
ARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATSGDYRHWADFGGERLSHTMDP
RAGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADAGPAG
>Mature_393_residues
SKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSNWKADSDLSRLNRATPGSWTPI
CANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGAAANRQADNEWAANRQAAGRHTVDRRTVDRHTADRHTADRQT
KDGRTPDRQPARPADPANGLSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRARRLADVAFDLCGIAKGFGVDELA
RVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATSGDYRHWADFGGERLSHTMDPR
AGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCAHAERHGLDALFVVRDGDALRTIGCGAFADAGPAG

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=163, Percent_Identity=36.1963190184049, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 41570; Mature: 41439

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSN
CCCCCCCCCCCCHHHHHHCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
WKADSDLSRLNRATPGSWTPICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGA
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCCC
AANRQADNEWAANRQAAGRHTVDRRTVDRHTADRHTADRQTKDGRTPDRQPARPADPANG
CCCCCCCCHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
LSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRARRLADVAFDLCGIAKGFGVDEL
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATS
HHHHHHCCCCEEEEECCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC
GDYRHWADFGGERLSHTMDPRAGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCA
CCCHHHHHCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCH
HAERHGLDALFVVRDGDALRTIGCGAFADAGPAG
HHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SKTSIEWSPGARLNRCRASGATMGTRYGAQFYAPPTADARAIAAALDAAVRAVDAQMSN
CCCCCCCCCCCHHHHHHCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHC
WKADSDLSRLNRATPGSWTPICANLAAVLVRAREIGRETDNAFNIGVGTLVDRWGFGPGA
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHCCCCCCC
AANRQADNEWAANRQAAGRHTVDRRTVDRHTADRHTADRQTKDGRTPDRQPARPADPANG
CCCCCCCCHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
LSGAIDARRRASILRGPVPSPCRPIDELLEVDVARGRARRLADVAFDLCGIAKGFGVDEL
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ARVLDRHGIGAWLVGIDGELRARGCKPDGSPWAIALEAPDYGRRGAMGAIDLVDAAVATS
HHHHHHCCCCEEEEECCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCC
GDYRHWADFGGERLSHTMDPRAGAPLRGDIASVTVVAPTCTDADAYATALMVLGAQAGCA
CCCHHHHHCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCH
HAERHGLDALFVVRDGDALRTIGCGAFADAGPAG
HHHHCCCCEEEEEECCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]