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The map label for this gene is CYP102A1 [H]

Identifier: 76819144

GI number: 76819144

Start: 676770

End: 679109

Strand: Direct

Name: CYP102A1 [H]

Synonym: BURPS1710b_A0493

Alternate gene names: 76819144

Gene position: 676770-679109 (Clockwise)

Preceding gene: 76817320

Following gene: 76819747

Centisome position: 21.27

GC content: 73.42

Gene sequence:

>2340_bases
ATGCTGCGCCAGCTTCATTCGATTCCCGGCCTGATCGCCGCCGCGCTCCTGATCGTCGTCACGCTGACGGGCGCGGCGCT
GTCGATCCAGCCCGCGCTCGAGCGCGCGGCCGTCGCCGGCCCCCCGCGCGCGCCGCTCGACGTCGCGACGCTCGCCGGCC
GCGTGAGCGCGCAGGTGCCGGGCGTCGAGAAGCTCGTGCGCCGGCCGTCCGGCGAAATCGTCGCGTACTACGCGGGCACC
GACGGGCCGCGCGCATCGATCGTCGATCCGTCGACCGGCGCGCCGCTCGCCGATTATCGCCCGTCGCCCGTCGTGCGCTG
GCTCACGAACCTGCACCGCAAGTTCCTGCTCGGCGACGCCGGGCGGATCGCGACGGGCGTGACCGCCGCCGCGATGCTGT
TCATCGCGCTGTCCGGGCTCGCGCTGCTCGCTCACCGGATGGGCGGCTGGCGGCGCCTGGCGGGCCCGATTCGCGGCGAC
GGATTGCAGCGGCTGCACAACGAGACCGCGCGCGTCGCGCTCGCGGGGCTCGTGCTGTCGGCGTTGACCGGGCTGGTGCT
GTCGCTGTCGACGTTCGGCGTGATTCCCGAGCGCGGCGCGGCGTCGGCGCTCGCGCTCGACGCGCGCCCGGGCATCGCCG
CCGCGGCGAAGGCGCCGATACCCATCGCGCAAATGGCCGCGCTGCGCGCCACTGATTGGTCGACGCTGCGCCAACTGAGC
TTTCCCGCGCCGGACGAGCCGCGCGGCCTGATCGAATTGAAGACGACCGACGGCGCCGGCTTCGTCGATCCGGCGACGGG
CGCCGCGCTCGCCTACCAGCCCGCAGACGGCTGGCAGCGCCTGCACGCGCTCGTGAAGATGCTGCACACGGGCGAAGGAT
TGTGGTGGCTCGGGCTCGTGCTCGGCGCATCGTCGCTCGCCACGCCGCTGCTCGCGGTGACGGGCGTGATGCTGTGGGCG
CGCCGGCGGCGCGCGCAGCCCAAGCGCGCCGGCGATGCGCCGGCGCGCGACGCGGACACCGTGCTGCTCGTCGGCAGCGA
AGGCAACAGCACCTGGGGCTTCGCGTCGGCGCTGCAAGCGGCGCTCGCGCAGGCGGGCCGGCGCGTGCACGTCGCACCGA
TGAACGACGGCGCTCGCGGCTACCCCGCCGCGCGGCACGTGCTCGTGCTGAGCGCGACCTACGGCGACGGCGACGCGCCC
GGCAACGCGCAGTCATTCCTGCCGAAGCTCGCGCGGCTGTCGGCGGGGCAAGGCGCGTCATTCGCGGTGCTCGGTTTCGG
CGATCGCCAGTTTCCGCGGTTTTGCGGCTACGCGCGAAGCGTCCATGACGCGCTCGTCGCGAAAGGCCTGACACCGCTGC
TCGATCTCGGCACCGTCGACAGGCAATCGGAGCCCGAATTCCGCGCGTGGTGCGCGCGGCTCGGCGATGCGCTCGGGCTC
GCGCTCGACGTCCGCCATGCGCCGACGCTGCCGCGCACGATGCCGCTCACGCTCGTCGAGCGCGACGACTACGGCGGCGA
TCCGCGAGCGATGACGTCGGTGCTGCGCTTCGCGCCCGCCGGGCGAGATGGCCGCACCGGCCGCGCGGACCGGGCCGGAC
GTGATGAACACGATGAACGCGATGGGCGTGAACGACGTCAAGAACGCGAAGAACGGCTCGAGGATGCCGGCCGGCGGGCC
GCATGGTGGACGGCGTTCGCGCGGCGGCGGCTGCCGTCGTTCGAAACCGGCGATCTGCTCGGCGTCGTGCCGCCGGGCGA
AGCTTCGCCGCGCTACTACTCGCTCGCAAGCGCCTCGTCGGACGGCATCGTCGAGATCTGCGTGCGCCGCCATCCGCACG
GCGTGTGCTCGCGCTATCTGACCGGCCTGCAACCGGGCGACACGATCGAGGCGTTCGTTCGCCCGCATGCGCGCCTGCGT
CCGCACGCGGGCGCGGCGCCGGTGATCCTGATCGGCGCGGGCACCGGCATCGGCCCGCTGATCGGCTTCATCCGGCACAA
CGCCGCGCGCCGCCCGATGCACTTGTACTTCGGCGCGCGCAACGCGAACGACGGCTTCCCGTACCGCGACGAGCTCGACG
GCCTCGTGCGCGACCGCCGGCTGCGCGCACTGACGACCGCGTTCTCGCGCGCGGAGCGCGGAGCCTACGTGCAGGACCGG
CTCGTCGCCGACGCGCGCAACCTGCGCGAGCTCGTCGCGCACGGCGCACAAATCATGGTGTGCGGCGGCCGCGCGATGGC
CGACGGCGTCGCGCGCGCGTGGGAGCGCATCCTGGCGGATTCCGGCTCGTCCGTCGCGCAATTGAAGCAGCAGGGGCGCT
ATGTCGAAGACGTCTATTGA

Upstream 100 bases:

>100_bases
CGTGCCGCTCAACGCGGCGGGCGCCGGCAAGGCGGTCAAGGGCCGCGGCTACGTGAAGTCGTTCCGCTATTCGCTGTAAC
ACGAAGACGAGAGGTACCCC

Downstream 100 bases:

>100_bases
ATGGTCGCCCGGCGCGCGGCTGAATCGCTGCCGCGCAAGCGGCGCGACGATGGGCACGCGCTACGGCGCGCAGTTCTACG
CGCCGCCGACGGCCGACGCG

Product: sulfite reductase (NADPH) flavoprotein alpha-component

Products: NA

Alternate protein names: Cytochrome P450(BM-3); Cytochrome P450BM-3; Cytochrome P450 102; NADPH--cytochrome P450 reductase [H]

Number of amino acids: Translated: 779; Mature: 779

Protein sequence:

>779_residues
MLRQLHSIPGLIAAALLIVVTLTGAALSIQPALERAAVAGPPRAPLDVATLAGRVSAQVPGVEKLVRRPSGEIVAYYAGT
DGPRASIVDPSTGAPLADYRPSPVVRWLTNLHRKFLLGDAGRIATGVTAAAMLFIALSGLALLAHRMGGWRRLAGPIRGD
GLQRLHNETARVALAGLVLSALTGLVLSLSTFGVIPERGAASALALDARPGIAAAAKAPIPIAQMAALRATDWSTLRQLS
FPAPDEPRGLIELKTTDGAGFVDPATGAALAYQPADGWQRLHALVKMLHTGEGLWWLGLVLGASSLATPLLAVTGVMLWA
RRRRAQPKRAGDAPARDADTVLLVGSEGNSTWGFASALQAALAQAGRRVHVAPMNDGARGYPAARHVLVLSATYGDGDAP
GNAQSFLPKLARLSAGQGASFAVLGFGDRQFPRFCGYARSVHDALVAKGLTPLLDLGTVDRQSEPEFRAWCARLGDALGL
ALDVRHAPTLPRTMPLTLVERDDYGGDPRAMTSVLRFAPAGRDGRTGRADRAGRDEHDERDGRERRQEREERLEDAGRRA
AWWTAFARRRLPSFETGDLLGVVPPGEASPRYYSLASASSDGIVEICVRRHPHGVCSRYLTGLQPGDTIEAFVRPHARLR
PHAGAAPVILIGAGTGIGPLIGFIRHNAARRPMHLYFGARNANDGFPYRDELDGLVRDRRLRALTTAFSRAERGAYVQDR
LVADARNLRELVAHGAQIMVCGGRAMADGVARAWERILADSGSSVAQLKQQGRYVEDVY

Sequences:

>Translated_779_residues
MLRQLHSIPGLIAAALLIVVTLTGAALSIQPALERAAVAGPPRAPLDVATLAGRVSAQVPGVEKLVRRPSGEIVAYYAGT
DGPRASIVDPSTGAPLADYRPSPVVRWLTNLHRKFLLGDAGRIATGVTAAAMLFIALSGLALLAHRMGGWRRLAGPIRGD
GLQRLHNETARVALAGLVLSALTGLVLSLSTFGVIPERGAASALALDARPGIAAAAKAPIPIAQMAALRATDWSTLRQLS
FPAPDEPRGLIELKTTDGAGFVDPATGAALAYQPADGWQRLHALVKMLHTGEGLWWLGLVLGASSLATPLLAVTGVMLWA
RRRRAQPKRAGDAPARDADTVLLVGSEGNSTWGFASALQAALAQAGRRVHVAPMNDGARGYPAARHVLVLSATYGDGDAP
GNAQSFLPKLARLSAGQGASFAVLGFGDRQFPRFCGYARSVHDALVAKGLTPLLDLGTVDRQSEPEFRAWCARLGDALGL
ALDVRHAPTLPRTMPLTLVERDDYGGDPRAMTSVLRFAPAGRDGRTGRADRAGRDEHDERDGRERRQEREERLEDAGRRA
AWWTAFARRRLPSFETGDLLGVVPPGEASPRYYSLASASSDGIVEICVRRHPHGVCSRYLTGLQPGDTIEAFVRPHARLR
PHAGAAPVILIGAGTGIGPLIGFIRHNAARRPMHLYFGARNANDGFPYRDELDGLVRDRRLRALTTAFSRAERGAYVQDR
LVADARNLRELVAHGAQIMVCGGRAMADGVARAWERILADSGSSVAQLKQQGRYVEDVY
>Mature_779_residues
MLRQLHSIPGLIAAALLIVVTLTGAALSIQPALERAAVAGPPRAPLDVATLAGRVSAQVPGVEKLVRRPSGEIVAYYAGT
DGPRASIVDPSTGAPLADYRPSPVVRWLTNLHRKFLLGDAGRIATGVTAAAMLFIALSGLALLAHRMGGWRRLAGPIRGD
GLQRLHNETARVALAGLVLSALTGLVLSLSTFGVIPERGAASALALDARPGIAAAAKAPIPIAQMAALRATDWSTLRQLS
FPAPDEPRGLIELKTTDGAGFVDPATGAALAYQPADGWQRLHALVKMLHTGEGLWWLGLVLGASSLATPLLAVTGVMLWA
RRRRAQPKRAGDAPARDADTVLLVGSEGNSTWGFASALQAALAQAGRRVHVAPMNDGARGYPAARHVLVLSATYGDGDAP
GNAQSFLPKLARLSAGQGASFAVLGFGDRQFPRFCGYARSVHDALVAKGLTPLLDLGTVDRQSEPEFRAWCARLGDALGL
ALDVRHAPTLPRTMPLTLVERDDYGGDPRAMTSVLRFAPAGRDGRTGRADRAGRDEHDERDGRERRQEREERLEDAGRRA
AWWTAFARRRLPSFETGDLLGVVPPGEASPRYYSLASASSDGIVEICVRRHPHGVCSRYLTGLQPGDTIEAFVRPHARLR
PHAGAAPVILIGAGTGIGPLIGFIRHNAARRPMHLYFGARNANDGFPYRDELDGLVRDRRLRALTTAFSRAERGAYVQDR
LVADARNLRELVAHGAQIMVCGGRAMADGVARAWERILADSGSSVAQLKQQGRYVEDVY

Specific function: Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is re

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=223, Percent_Identity=34.0807174887892, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI40254422, Length=278, Percent_Identity=32.0143884892086, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI24041029, Length=225, Percent_Identity=31.5555555555556, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI10835173, Length=225, Percent_Identity=32.8888888888889, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1789123, Length=216, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17554134, Length=228, Percent_Identity=35.0877192982456, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17566446, Length=171, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325305, Length=194, Percent_Identity=28.8659793814433, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321832, Length=177, Percent_Identity=33.8983050847458, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583543, Length=224, Percent_Identity=31.25, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI78706876, Length=224, Percent_Identity=31.25, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI78706872, Length=224, Percent_Identity=31.25, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582192, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137192, Length=224, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023206
- InterPro:   IPR001128
- InterPro:   IPR015702
- InterPro:   IPR017972
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1; PF00067 p450 [H]

EC number: =1.14.14.1; =1.6.2.4 [H]

Molecular weight: Translated: 83057; Mature: 83057

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRQLHSIPGLIAAALLIVVTLTGAALSIQPALERAAVAGPPRAPLDVATLAGRVSAQVP
CCCHHHHCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
GVEKLVRRPSGEIVAYYAGTDGPRASIVDPSTGAPLADYRPSPVVRWLTNLHRKFLLGDA
CHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GRIATGVTAAAMLFIALSGLALLAHRMGGWRRLAGPIRGDGLQRLHNETARVALAGLVLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALTGLVLSLSTFGVIPERGAASALALDARPGIAAAAKAPIPIAQMAALRATDWSTLRQLS
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHCC
FPAPDEPRGLIELKTTDGAGFVDPATGAALAYQPADGWQRLHALVKMLHTGEGLWWLGLV
CCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHH
LGASSLATPLLAVTGVMLWARRRRAQPKRAGDAPARDADTVLLVGSEGNSTWGFASALQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
ALAQAGRRVHVAPMNDGARGYPAARHVLVLSATYGDGDAPGNAQSFLPKLARLSAGQGAS
HHHHCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
FAVLGFGDRQFPRFCGYARSVHDALVAKGLTPLLDLGTVDRQSEPEFRAWCARLGDALGL
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCE
ALDVRHAPTLPRTMPLTLVERDDYGGDPRAMTSVLRFAPAGRDGRTGRADRAGRDEHDER
EEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
DGRERRQEREERLEDAGRRAAWWTAFARRRLPSFETGDLLGVVPPGEASPRYYSLASASS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEECCCCC
DGIVEICVRRHPHGVCSRYLTGLQPGDTIEAFVRPHARLRPHAGAAPVILIGAGTGIGPL
CCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHCCCHHCCCCCCCCCEEEEECCCCHHHH
IGFIRHNAARRPMHLYFGARNANDGFPYRDELDGLVRDRRLRALTTAFSRAERGAYVQDR
HHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LVADARNLRELVAHGAQIMVCGGRAMADGVARAWERILADSGSSVAQLKQQGRYVEDVY
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MLRQLHSIPGLIAAALLIVVTLTGAALSIQPALERAAVAGPPRAPLDVATLAGRVSAQVP
CCCHHHHCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
GVEKLVRRPSGEIVAYYAGTDGPRASIVDPSTGAPLADYRPSPVVRWLTNLHRKFLLGDA
CHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GRIATGVTAAAMLFIALSGLALLAHRMGGWRRLAGPIRGDGLQRLHNETARVALAGLVLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ALTGLVLSLSTFGVIPERGAASALALDARPGIAAAAKAPIPIAQMAALRATDWSTLRQLS
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCHHHCCCCCCHHHHHHHHCCCHHHHHHCC
FPAPDEPRGLIELKTTDGAGFVDPATGAALAYQPADGWQRLHALVKMLHTGEGLWWLGLV
CCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHH
LGASSLATPLLAVTGVMLWARRRRAQPKRAGDAPARDADTVLLVGSEGNSTWGFASALQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
ALAQAGRRVHVAPMNDGARGYPAARHVLVLSATYGDGDAPGNAQSFLPKLARLSAGQGAS
HHHHCCCEEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCC
FAVLGFGDRQFPRFCGYARSVHDALVAKGLTPLLDLGTVDRQSEPEFRAWCARLGDALGL
EEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCE
ALDVRHAPTLPRTMPLTLVERDDYGGDPRAMTSVLRFAPAGRDGRTGRADRAGRDEHDER
EEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
DGRERRQEREERLEDAGRRAAWWTAFARRRLPSFETGDLLGVVPPGEASPRYYSLASASS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEECCCCC
DGIVEICVRRHPHGVCSRYLTGLQPGDTIEAFVRPHARLRPHAGAAPVILIGAGTGIGPL
CCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHCCCHHCCCCCCCCCEEEEECCCCHHHH
IGFIRHNAARRPMHLYFGARNANDGFPYRDELDGLVRDRRLRALTTAFSRAERGAYVQDR
HHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LVADARNLRELVAHGAQIMVCGGRAMADGVARAWERILADSGSSVAQLKQQGRYVEDVY
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544578; 1727637; 8342039; 9033595; 10051560; 11695892 [H]