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The map label for this gene is ribD [H]

Identifier: 76819539

GI number: 76819539

Start: 114364

End: 115728

Strand: Direct

Name: ribD [H]

Synonym: BURPS1710b_A0085

Alternate gene names: 76819539

Gene position: 114364-115728 (Clockwise)

Preceding gene: 76818972

Following gene: 76817238

Centisome position: 3.59

GC content: 76.48

Gene sequence:

>1365_bases
ATGGCCGCTATCAGCGCGACATCTACGCGATGGGTTTTCGCCTCGTGGAGTCGCGATGAACGCCGGATCGAGCGCCGGCC
GGCGCGGACGGCTTCCGTCGATGCAACCCGCCCCCGAGGCGCGAGCGGCGCGGGCGGTGCACGCGCCGCACTCGACCGAG
CGGACGGGCCGCCGACGATGAGCGCGTTCTCCGACATCGACCGCACGCACATGGCCCATGCGCTGCGGCTCGCCGAACAG
GGGCTTTACACGACGCATCCGAACCCGCGCGTGGGCTGCGTGATCGCGCGCGGTGCCCGCACGCTCGGCGCGGGCTGGCA
CCGCCGCGCAGGCGAACCGCACGCGGAAGTGCACGCGCTGCGCGAAGCGGGCGAGCGCGCACGCGGCGCGACCGCGTACG
TGACGCTCGAGCCCTGCGCGCACTTCGGCAGGACGCCGCCGTGCGCGAACGCGCTCGTCGCGGCGGGCGTCGCGCGCGTC
GTGATCGCCGCGCGCGATCCGTTCGAGCAGGTCGCCGGGCGCGGCGCGGCGCGCCTGGCCGACGCGGGCATCGTCGTCGA
GCAGGGGCTGCTGGCGGCGCAGGCGCGCGAGCTGAACATCGGCTTCTTCAGCCGGATCGAGCGCGGCCGGCCGTGGACGC
GCGCGACGCTGGGCTTGCCGATCGACGCCCCGCCGGCGCTCGATTCGGCCGAGCTGGCGGCGCTTGACGCGGCGCTGTCC
GAGGCGCGCGACGATCTCCGGCACTGGCGCGCGCGCAGCTCGCTCGTGCTCGAACGCGCGCCCGACGCCGGGCGCGCCGT
CGGGTGCAACGCAGCCGCGCCCCGCTACGTCGTGAGCGCGCGGGACTGCGCGGCGCTCGGCGCGGCGAGCGCCGCGTGCG
CGCCCGCCGACGGCGTGCCGACGCTCGCGCTGCATCGCGACGACAACAGCGCAAGCGCATGCGAAGACGCGCACGGCATC
GGCCATCGTGCCCGTCGCGTCGATCGCGTCGATCACGCCGATGCGCGGCCCGCCGGCGCACCGTCGGCTTCGGCTTCCGA
CACCGACGCCGGCCTGCCCCTGCCCGACGCGTTCGCGCGGCTCGCGCGGCAAGGCGTCAACGAGCTGCTCGTCGACGCCG
ATCTTGCGTTGTGCGACGCGCTGTTCGGCAGCGATCTCGCCGACGAGCTGCTGCTGTACGCGCACCCGGCGCGCCGCGAC
GCGCCCGTATCGGCGTCGCGGCTCGCCGCGGCGATCGACGACGTCGCGCGCCGCTGGGGCCTGCGGCCGCTCGAGCGTCT
CGCGATCGGCCGCGGCGAGCGGATCCTGCTGCGCCGCGCGCGCGGGCCCGAGCCCCGGCAAGGCGAGCCGGGCGTCATCC
CCTAG

Upstream 100 bases:

>100_bases
GCGATCGCCGATGACCTCGCCGTCACGCAGGGCGGCTACCGGATCGCGCGCGGCGGCAGCTTCACGCGCTTCGGCGATCT
CGCGCGCTGCGCGCGCCGCC

Downstream 100 bases:

>100_bases
CCGCGCGGCGCATCGCCGCGCACCGCTTTATTTCAGGACCACATCGAACGAGGACCTCAATGAACGCATCCGCAGTCGAG
ACCATCTACGAGTCGACCGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAAISATSTRWVFASWSRDERRIERRPARTASVDATRPRGASGAGGARAALDRADGPPTMSAFSDIDRTHMAHALRLAEQ
GLYTTHPNPRVGCVIARGARTLGAGWHRRAGEPHAEVHALREAGERARGATAYVTLEPCAHFGRTPPCANALVAAGVARV
VIAARDPFEQVAGRGAARLADAGIVVEQGLLAAQARELNIGFFSRIERGRPWTRATLGLPIDAPPALDSAELAALDAALS
EARDDLRHWRARSSLVLERAPDAGRAVGCNAAAPRYVVSARDCAALGAASAACAPADGVPTLALHRDDNSASACEDAHGI
GHRARRVDRVDHADARPAGAPSASASDTDAGLPLPDAFARLARQGVNELLVDADLALCDALFGSDLADELLLYAHPARRD
APVSASRLAAAIDDVARRWGLRPLERLAIGRGERILLRRARGPEPRQGEPGVIP

Sequences:

>Translated_454_residues
MAAISATSTRWVFASWSRDERRIERRPARTASVDATRPRGASGAGGARAALDRADGPPTMSAFSDIDRTHMAHALRLAEQ
GLYTTHPNPRVGCVIARGARTLGAGWHRRAGEPHAEVHALREAGERARGATAYVTLEPCAHFGRTPPCANALVAAGVARV
VIAARDPFEQVAGRGAARLADAGIVVEQGLLAAQARELNIGFFSRIERGRPWTRATLGLPIDAPPALDSAELAALDAALS
EARDDLRHWRARSSLVLERAPDAGRAVGCNAAAPRYVVSARDCAALGAASAACAPADGVPTLALHRDDNSASACEDAHGI
GHRARRVDRVDHADARPAGAPSASASDTDAGLPLPDAFARLARQGVNELLVDADLALCDALFGSDLADELLLYAHPARRD
APVSASRLAAAIDDVARRWGLRPLERLAIGRGERILLRRARGPEPRQGEPGVIP
>Mature_453_residues
AAISATSTRWVFASWSRDERRIERRPARTASVDATRPRGASGAGGARAALDRADGPPTMSAFSDIDRTHMAHALRLAEQG
LYTTHPNPRVGCVIARGARTLGAGWHRRAGEPHAEVHALREAGERARGATAYVTLEPCAHFGRTPPCANALVAAGVARVV
IAARDPFEQVAGRGAARLADAGIVVEQGLLAAQARELNIGFFSRIERGRPWTRATLGLPIDAPPALDSAELAALDAALSE
ARDDLRHWRARSSLVLERAPDAGRAVGCNAAAPRYVVSARDCAALGAASAACAPADGVPTLALHRDDNSASACEDAHGIG
HRARRVDRVDHADARPAGAPSASASDTDAGLPLPDAFARLARQGVNELLVDADLALCDALFGSDLADELLLYAHPARRDA
PVSASRLAAAIDDVARRWGLRPLERLAIGRGERILLRRARGPEPRQGEPGVIP

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=343, Percent_Identity=39.3586005830904, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=34.3949044585987, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 47842; Mature: 47711

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAISATSTRWVFASWSRDERRIERRPARTASVDATRPRGASGAGGARAALDRADGPPTM
CCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCH
SAFSDIDRTHMAHALRLAEQGLYTTHPNPRVGCVIARGARTLGAGWHRRAGEPHAEVHAL
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCHHHCCCHHHCCCCCHHHHHHH
REAGERARGATAYVTLEPCAHFGRTPPCANALVAAGVARVVIAARDPFEQVAGRGAARLA
HHHHHHHCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
DAGIVVEQGLLAAQARELNIGFFSRIERGRPWTRATLGLPIDAPPALDSAELAALDAALS
HCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH
EARDDLRHWRARSSLVLERAPDAGRAVGCNAAAPRYVVSARDCAALGAASAACAPADGVP
HHHHHHHHHHHHHHHHEECCCCCCCEECCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCC
TLALHRDDNSASACEDAHGIGHRARRVDRVDHADARPAGAPSASASDTDAGLPLPDAFAR
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LARQGVNELLVDADLALCDALFGSDLADELLLYAHPARRDAPVSASRLAAAIDDVARRWG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
LRPLERLAIGRGERILLRRARGPEPRQGEPGVIP
CCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAISATSTRWVFASWSRDERRIERRPARTASVDATRPRGASGAGGARAALDRADGPPTM
CCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCH
SAFSDIDRTHMAHALRLAEQGLYTTHPNPRVGCVIARGARTLGAGWHRRAGEPHAEVHAL
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCHHHCCCHHHCCCCCHHHHHHH
REAGERARGATAYVTLEPCAHFGRTPPCANALVAAGVARVVIAARDPFEQVAGRGAARLA
HHHHHHHCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHH
DAGIVVEQGLLAAQARELNIGFFSRIERGRPWTRATLGLPIDAPPALDSAELAALDAALS
HCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHH
EARDDLRHWRARSSLVLERAPDAGRAVGCNAAAPRYVVSARDCAALGAASAACAPADGVP
HHHHHHHHHHHHHHHHEECCCCCCCEECCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCC
TLALHRDDNSASACEDAHGIGHRARRVDRVDHADARPAGAPSASASDTDAGLPLPDAFAR
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LARQGVNELLVDADLALCDALFGSDLADELLLYAHPARRDAPVSASRLAAAIDDVARRWG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHC
LRPLERLAIGRGERILLRRARGPEPRQGEPGVIP
CCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]