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The map label for this gene is toxD [H]

Identifier: 76818972

GI number: 76818972

Start: 113439

End: 114422

Strand: Direct

Name: toxD [H]

Synonym: BURPS1710b_A0084

Alternate gene names: 76818972

Gene position: 113439-114422 (Clockwise)

Preceding gene: 76818103

Following gene: 76819539

Centisome position: 3.57

GC content: 71.44

Gene sequence:

>984_bases
ATGACGCTCAAGCTGGCCGACAACCCGAACCGCCTCAGCGACCGCGCGGCCATGGCGCTGCCGGACGATCTGTTCGTCGC
GCGCACGAGCGCGACGGTCCTCTCGACGCATGTCGATTTGCTGCGCATGACGAGCGCGCAGTGGATCGCGATCGCCGAGG
CTCCCGACGCGCCGTTCGAGCGGCGCTACGCGGCGGGCACGCTGCTCGGATTCGCGGGCGATCCGCGCATCCGAGCGCTC
GATCCGCCGATGTGCGACGTGCCCGCCGCGCGCGCGCGGCTCGGCACCGAGCCGGCGCGCGTGCCGCAGGTGATCGCCGA
ATGGTCGCGCGTCGGCGTGATCGACGAATGGATCGAGAAGGAATGCCCGCGCCATACGGTCGAGCTCGCCGCGTACCGGA
TGATGCGCTACCCGGTCACGAACCTCGAATACCGGCGGTTCCTCGAGGAGACGGGCGCGCCGTGGCTGCCGACCTCGTGG
ACGTTCGGCGTCTACCCGCTCGAGCGCGCGAACCATCCGGTCTGGTCGGTGCCCGCCGAGGCCGCCGACGCGTACGCGGC
CTGGCTCTGCGAAGCAACCGGCCGGCGCTTCCGGCTGCCGACCGAGGCCGAATGGGAGTACGCGGCGTCGGGCGGCGCGG
ACGTCGAGTATCCGTGGGGCGACGCGTTCGATCCGCGTGCGGCGAACACGGTCGAGGCGGGGCCGCTGTCGACGACGCCC
GTCGGCATCTTTCCGCTCGGGCGCAGCGCGTTCGGCATCGACGATCTCGCCGGCAACGTCGAGGAATACGTCGCCGACGA
CTATCGCCCGTATCCGGGCGGCGAGGCGATCGCCGATGACCTCGCCGTCACGCAGGGCGGCTACCGGATCGCGCGCGGCG
GCAGCTTCACGCGCTTCGGCGATCTCGCGCGCTGCGCGCGCCGCCATGGCCGCTATCAGCGCGACATCTACGCGATGGGT
TTTCGCCTCGTGGAGTCGCGATGA

Upstream 100 bases:

>100_bases
CCCCCGTCGACAGCCAGCGGGTGCCGCGGCCGAAAGCCGGCCTGCACTATCTGGTGATGACGGCCCGCAAAACCGATTCG
ACTGACGCGAGTGCACGCCG

Downstream 100 bases:

>100_bases
ACGCCGGATCGAGCGCCGGCCGGCGCGGACGGCTTCCGTCGATGCAACCCGCCCCCGAGGCGCGAGCGGCGCGGGCGGTG
CACGCGCCGCACTCGACCGA

Product: TRP-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTLKLADNPNRLSDRAAMALPDDLFVARTSATVLSTHVDLLRMTSAQWIAIAEAPDAPFERRYAAGTLLGFAGDPRIRAL
DPPMCDVPAARARLGTEPARVPQVIAEWSRVGVIDEWIEKECPRHTVELAAYRMMRYPVTNLEYRRFLEETGAPWLPTSW
TFGVYPLERANHPVWSVPAEAADAYAAWLCEATGRRFRLPTEAEWEYAASGGADVEYPWGDAFDPRAANTVEAGPLSTTP
VGIFPLGRSAFGIDDLAGNVEEYVADDYRPYPGGEAIADDLAVTQGGYRIARGGSFTRFGDLARCARRHGRYQRDIYAMG
FRLVESR

Sequences:

>Translated_327_residues
MTLKLADNPNRLSDRAAMALPDDLFVARTSATVLSTHVDLLRMTSAQWIAIAEAPDAPFERRYAAGTLLGFAGDPRIRAL
DPPMCDVPAARARLGTEPARVPQVIAEWSRVGVIDEWIEKECPRHTVELAAYRMMRYPVTNLEYRRFLEETGAPWLPTSW
TFGVYPLERANHPVWSVPAEAADAYAAWLCEATGRRFRLPTEAEWEYAASGGADVEYPWGDAFDPRAANTVEAGPLSTTP
VGIFPLGRSAFGIDDLAGNVEEYVADDYRPYPGGEAIADDLAVTQGGYRIARGGSFTRFGDLARCARRHGRYQRDIYAMG
FRLVESR
>Mature_326_residues
TLKLADNPNRLSDRAAMALPDDLFVARTSATVLSTHVDLLRMTSAQWIAIAEAPDAPFERRYAAGTLLGFAGDPRIRALD
PPMCDVPAARARLGTEPARVPQVIAEWSRVGVIDEWIEKECPRHTVELAAYRMMRYPVTNLEYRRFLEETGAPWLPTSWT
FGVYPLERANHPVWSVPAEAADAYAAWLCEATGRRFRLPTEAEWEYAASGGADVEYPWGDAFDPRAANTVEAGPLSTTPV
GIFPLGRSAFGIDDLAGNVEEYVADDYRPYPGGEAIADDLAVTQGGYRIARGGSFTRFGDLARCARRHGRYQRDIYAMGF
RLVESR

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=277, Percent_Identity=28.158844765343, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38202250, Length=302, Percent_Identity=25.8278145695364, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI194248087, Length=204, Percent_Identity=31.3725490196078, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI194248088, Length=150, Percent_Identity=36.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226437577, Length=154, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 36249; Mature: 36118

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKLADNPNRLSDRAAMALPDDLFVARTSATVLSTHVDLLRMTSAQWIAIAEAPDAPFE
CEEEECCCCCHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
RRYAAGTLLGFAGDPRIRALDPPMCDVPAARARLGTEPARVPQVIAEWSRVGVIDEWIEK
HHHHHHEEEECCCCCCEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHH
ECPRHTVELAAYRMMRYPVTNLEYRRFLEETGAPWLPTSWTFGVYPLERANHPVWSVPAE
HCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCEECCHH
AADAYAAWLCEATGRRFRLPTEAEWEYAASGGADVEYPWGDAFDPRAANTVEAGPLSTTP
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VGIFPLGRSAFGIDDLAGNVEEYVADDYRPYPGGEAIADDLAVTQGGYRIARGGSFTRFG
EEEEECCCCCCCHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHH
DLARCARRHGRYQRDIYAMGFRLVESR
HHHHHHHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLKLADNPNRLSDRAAMALPDDLFVARTSATVLSTHVDLLRMTSAQWIAIAEAPDAPFE
EEEECCCCCHHHHHHHHCCCCHHEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
RRYAAGTLLGFAGDPRIRALDPPMCDVPAARARLGTEPARVPQVIAEWSRVGVIDEWIEK
HHHHHHEEEECCCCCCEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHH
ECPRHTVELAAYRMMRYPVTNLEYRRFLEETGAPWLPTSWTFGVYPLERANHPVWSVPAE
HCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCEECCHH
AADAYAAWLCEATGRRFRLPTEAEWEYAASGGADVEYPWGDAFDPRAANTVEAGPLSTTP
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VGIFPLGRSAFGIDDLAGNVEEYVADDYRPYPGGEAIADDLAVTQGGYRIARGGSFTRFG
EEEEECCCCCCCHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCHHHH
DLARCARRHGRYQRDIYAMGFRLVESR
HHHHHHHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]