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The map label for this gene is cynR [H]

Identifier: 76819189

GI number: 76819189

Start: 1640955

End: 1641869

Strand: Direct

Name: cynR [H]

Synonym: BURPS1710b_A1328

Alternate gene names: 76819189

Gene position: 1640955-1641869 (Clockwise)

Preceding gene: 76818902

Following gene: 76818903

Centisome position: 51.57

GC content: 64.37

Gene sequence:

>915_bases
ATGGATCAATCGTTTCAAGTCAACCTCAACCGCCTCCGCTACTTCCACGCGATCCTCGAGCACGGATCGATCCGCGCGGC
GGCTGAACGGCTGAACACAGCGCCGTCCGTCGTCAGCCGGCAGTTGCAGCTGCTCGAAAGCGAAATCGGCGCGCCGCTGT
TCGAGCGCCGCCAGCACGGCATGATCGCGACCGAAGCCGCGACGCTGCTCGTCGAATACACGCACGCGTGCCGAATCGGA
TTAGAGCAGTTCCACGAATCGCTGCACGGCGAATTGCGCGGGCGCGTCGAGATCGCGCTGACCGTCGGTTATGTCGAAGA
TCTGATGGACTCCGTCATTACCGGTTTTTTGCATCGGCATCCGCACGTGGCGGTCGAATTGAACGTGCGCACCGCCGACG
GCGTCGTAGATGACGTATTACGCAAACGTGCGCATATCGGCCTCACGTACAATCCGTCCCTGCCGCCCGAGATACGCGAA
TGCCTGAGCGTCGCGCATCCGACCTTTCTCGCGGTCGCGCCCGATCACCCGCTCGCGAAGCGCGGCGAGCCGCTCGAATT
GCGCGACGCGGTGCGCTATCCGCTCGCGCTGATGCCCGCGCCGTATTACGGCGTCGGGCAGATCGTGCATACCGTCGCGC
ACGCGGAGAACATTCCGCTTGCGCCGCGGCTCGTCACGAACTCGGTGCCGGCGATGCGGCGCTTCGTGCGCTCGGGCAAC
GGCGTCGCGTTTCTCACGCGGCTGCTTGTCGAAGACGATCTCGAGCGCGGCGAGATCGTCGCGCTGCGCATGCGCAACCC
GCTGTTCAATTCGCCCTGCGGCAAGGTGCTCGTTCATAACGAGCGCGCGCTGCCGCGCGCGGCGAACGAAATCCTCGCGC
GCATCGTGCGCGATTTGCCTTCGTTCAAGTCTTGA

Upstream 100 bases:

>100_bases
TACTCCTGCGCTCATTTGTCGTGGCCATTATCTCCATACTGTATGATCCCAGTGACAGCAACTTTGGTGTACAGCCGTTG
CCTTTCAGGGCAACAAGCGT

Downstream 100 bases:

>100_bases
ATCCTTCTTGAATCGCGCGCGCCGCGCGCCGCCGAATTGCTTCCGTTCGCGATGCTTTTCGCGCGCGCCGCGTCGATCGC
CTATCGACCGGAAGCGATCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Cyn operon transcriptional activator [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDQSFQVNLNRLRYFHAILEHGSIRAAAERLNTAPSVVSRQLQLLESEIGAPLFERRQHGMIATEAATLLVEYTHACRIG
LEQFHESLHGELRGRVEIALTVGYVEDLMDSVITGFLHRHPHVAVELNVRTADGVVDDVLRKRAHIGLTYNPSLPPEIRE
CLSVAHPTFLAVAPDHPLAKRGEPLELRDAVRYPLALMPAPYYGVGQIVHTVAHAENIPLAPRLVTNSVPAMRRFVRSGN
GVAFLTRLLVEDDLERGEIVALRMRNPLFNSPCGKVLVHNERALPRAANEILARIVRDLPSFKS

Sequences:

>Translated_304_residues
MDQSFQVNLNRLRYFHAILEHGSIRAAAERLNTAPSVVSRQLQLLESEIGAPLFERRQHGMIATEAATLLVEYTHACRIG
LEQFHESLHGELRGRVEIALTVGYVEDLMDSVITGFLHRHPHVAVELNVRTADGVVDDVLRKRAHIGLTYNPSLPPEIRE
CLSVAHPTFLAVAPDHPLAKRGEPLELRDAVRYPLALMPAPYYGVGQIVHTVAHAENIPLAPRLVTNSVPAMRRFVRSGN
GVAFLTRLLVEDDLERGEIVALRMRNPLFNSPCGKVLVHNERALPRAANEILARIVRDLPSFKS
>Mature_304_residues
MDQSFQVNLNRLRYFHAILEHGSIRAAAERLNTAPSVVSRQLQLLESEIGAPLFERRQHGMIATEAATLLVEYTHACRIG
LEQFHESLHGELRGRVEIALTVGYVEDLMDSVITGFLHRHPHVAVELNVRTADGVVDDVLRKRAHIGLTYNPSLPPEIRE
CLSVAHPTFLAVAPDHPLAKRGEPLELRDAVRYPLALMPAPYYGVGQIVHTVAHAENIPLAPRLVTNSVPAMRRFVRSGN
GVAFLTRLLVEDDLERGEIVALRMRNPLFNSPCGKVLVHNERALPRAANEILARIVRDLPSFKS

Specific function: Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR- cynTSX intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=231, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=131, Percent_Identity=32.0610687022901, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=24.8031496062992, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33907; Mature: 33907

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQSFQVNLNRLRYFHAILEHGSIRAAAERLNTAPSVVSRQLQLLESEIGAPLFERRQHG
CCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCC
MIATEAATLLVEYTHACRIGLEQFHESLHGELRGRVEIALTVGYVEDLMDSVITGFLHRH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHCC
PHVAVELNVRTADGVVDDVLRKRAHIGLTYNPSLPPEIRECLSVAHPTFLAVAPDHPLAK
CCEEEEEEEECHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHC
RGEPLELRDAVRYPLALMPAPYYGVGQIVHTVAHAENIPLAPRLVTNSVPAMRRFVRSGN
CCCCCCHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCC
GVAFLTRLLVEDDLERGEIVALRMRNPLFNSPCGKVLVHNERALPRAANEILARIVRDLP
CHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCC
SFKS
CCCC
>Mature Secondary Structure
MDQSFQVNLNRLRYFHAILEHGSIRAAAERLNTAPSVVSRQLQLLESEIGAPLFERRQHG
CCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHCC
MIATEAATLLVEYTHACRIGLEQFHESLHGELRGRVEIALTVGYVEDLMDSVITGFLHRH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHCC
PHVAVELNVRTADGVVDDVLRKRAHIGLTYNPSLPPEIRECLSVAHPTFLAVAPDHPLAK
CCEEEEEEEECHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHC
RGEPLELRDAVRYPLALMPAPYYGVGQIVHTVAHAENIPLAPRLVTNSVPAMRRFVRSGN
CCCCCCHHHHHHCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCC
GVAFLTRLLVEDDLERGEIVALRMRNPLFNSPCGKVLVHNERALPRAANEILARIVRDLP
CHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCC
SFKS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]