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The map label for this gene is irlR2 [H]

Identifier: 76819077

GI number: 76819077

Start: 1381218

End: 1381910

Strand: Direct

Name: irlR2 [H]

Synonym: BURPS1710b_A1103

Alternate gene names: 76819077

Gene position: 1381218-1381910 (Clockwise)

Preceding gene: 76817382

Following gene: 76819668

Centisome position: 43.41

GC content: 63.64

Gene sequence:

>693_bases
ATGAAGGTCCTTATCGTAGAAGACGAGCCGAAGACGGGCATGTATTTGAAGCGCGGGCTCACCGAAGCGGGCTTCGTCTG
CGACTGGACACAGGACGGCATCAGCGGTCTGCATCAGTTGCAGACGGAGAACTACGATCTCGCGATCCTCGACGTGATGC
TGCCCGGTTGCGACGGCTGGACAGTCGTGCGCGAGCTGCGCAGAACGCACCGCACGCCGGTGCTGTTCCTCACCGCGCGC
GATCACGTCGACGATCGCGTGAAAGGCCTCGAGCTCGGCGGCGACGACTATCTCGCGAAGCCGTTCGATTTCGCCGAATT
GCTCGCGCGTGTGCGCTCGCTGCTGCGGCGCGGCCAGGCAACCGATGCGCCGGTGCTGCGCGTCGCCAATCTCGAGCTCG
ATCTCATCCAGCGCAAGGCGCGCCGCCAGGGCAACACGATCCTGCTCACCGCTAAGGAATTCCTGCTGCTATGGCTGCTG
ATGCGCCGGCAGGGCGAGATCCTGCCGCGCTCGCTGATCGCATCGCAGATCTGGGACATCAACTTCGACAGCGATTCGAA
CGTCGTCGACGCGGCGATCAAGCGCGTGCGCGCGAAGGTCGATCAGGACTACGAGCCCAAGCTGATCCACACGGTGCGTG
GAATGGGATACGTTCTCGAGCAGCGGGGCGAGCCGTGCGAATCGTGTGCATGA

Upstream 100 bases:

>100_bases
CAATCTTCAAATCGCATGTTCAATCATGCACACCGAAATGTTGAACTGTGAACGACACGCATTCTCAAAGAAAATTTAAC
GCGTTCTTAATGAGTTTGAA

Downstream 100 bases:

>100_bases
TGCGCCGCCTCGCGCCGCGCACGATGCGCGCGCGGCTGGCGATCAAGTTCGCGCTGTCGACATCGGTGCTGCTCGCGATC
AGCGGCCTGCTGCTGTACGA

Product: DNA-binding response regulator IrlR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKVLIVEDEPKTGMYLKRGLTEAGFVCDWTQDGISGLHQLQTENYDLAILDVMLPGCDGWTVVRELRRTHRTPVLFLTAR
DHVDDRVKGLELGGDDYLAKPFDFAELLARVRSLLRRGQATDAPVLRVANLELDLIQRKARRQGNTILLTAKEFLLLWLL
MRRQGEILPRSLIASQIWDINFDSDSNVVDAAIKRVRAKVDQDYEPKLIHTVRGMGYVLEQRGEPCESCA

Sequences:

>Translated_230_residues
MKVLIVEDEPKTGMYLKRGLTEAGFVCDWTQDGISGLHQLQTENYDLAILDVMLPGCDGWTVVRELRRTHRTPVLFLTAR
DHVDDRVKGLELGGDDYLAKPFDFAELLARVRSLLRRGQATDAPVLRVANLELDLIQRKARRQGNTILLTAKEFLLLWLL
MRRQGEILPRSLIASQIWDINFDSDSNVVDAAIKRVRAKVDQDYEPKLIHTVRGMGYVLEQRGEPCESCA
>Mature_230_residues
MKVLIVEDEPKTGMYLKRGLTEAGFVCDWTQDGISGLHQLQTENYDLAILDVMLPGCDGWTVVRELRRTHRTPVLFLTAR
DHVDDRVKGLELGGDDYLAKPFDFAELLARVRSLLRRGQATDAPVLRVANLELDLIQRKARRQGNTILLTAKEFLLLWLL
MRRQGEILPRSLIASQIWDINFDSDSNVVDAAIKRVRAKVDQDYEPKLIHTVRGMGYVLEQRGEPCESCA

Specific function: Member of the two-component regulatory system irlR/irlS. May be involved in invasion of eukaryotic cells and heavy-metal resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=60.8108108108108, Blast_Score=274, Evalue=3e-75,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=53.4562211981567, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=41.2556053811659, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=36.8181818181818, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=39.0134529147982, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=32.7354260089686, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=35.0877192982456, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=35.6164383561644, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=35.7466063348416, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.4444444444444, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.8421052631579, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=32.8888888888889, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=31.858407079646, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=30.4347826086957, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.8943089430894, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=36.8932038834951, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=144, Percent_Identity=27.0833333333333, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26172; Mature: 26172

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLIVEDEPKTGMYLKRGLTEAGFVCDWTQDGISGLHQLQTENYDLAILDVMLPGCDGW
CEEEEEECCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCH
TVVRELRRTHRTPVLFLTARDHVDDRVKGLELGGDDYLAKPFDFAELLARVRSLLRRGQA
HHHHHHHHHCCCCEEEEEECCCHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCC
TDAPVLRVANLELDLIQRKARRQGNTILLTAKEFLLLWLLMRRQGEILPRSLIASQIWDI
CCCCEEEEECCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
NFDSDSNVVDAAIKRVRAKVDQDYEPKLIHTVRGMGYVLEQRGEPCESCA
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKVLIVEDEPKTGMYLKRGLTEAGFVCDWTQDGISGLHQLQTENYDLAILDVMLPGCDGW
CEEEEEECCCCCCHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCH
TVVRELRRTHRTPVLFLTARDHVDDRVKGLELGGDDYLAKPFDFAELLARVRSLLRRGQA
HHHHHHHHHCCCCEEEEEECCCHHHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCC
TDAPVLRVANLELDLIQRKARRQGNTILLTAKEFLLLWLLMRRQGEILPRSLIASQIWDI
CCCCEEEEECCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
NFDSDSNVVDAAIKRVRAKVDQDYEPKLIHTVRGMGYVLEQRGEPCESCA
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9393784 [H]