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The map label for this gene is dac [H]

Identifier: 76818571

GI number: 76818571

Start: 353920

End: 354921

Strand: Direct

Name: dac [H]

Synonym: BURPS1710b_A0238

Alternate gene names: 76818571

Gene position: 353920-354921 (Clockwise)

Preceding gene: 76818185

Following gene: 76818629

Centisome position: 11.12

GC content: 72.26

Gene sequence:

>1002_bases
ATGACGACCGAGCCTCTTTCGACAACCGTCGCACGCGGCAGCCGCCGCGCGGCATGTGCGCTGCTCCGCACGCCCTCGCG
CCTGTTCGCCTCGCTCTTCGTGTCCGCGGCATGCGCCGCGCCGAACGGCGCGCGAGCCGCGCCGGCCCCGGCACCGGCGA
TCCAGGCCGCGTCCTGGCTCGTCGTCGACGCCGATTCCGGCAAGACGCTCGGCGCGCACAATGTCGACGCGCGCCGCGAG
CCGGCGTCGCTGACCAAGCTGATGACCGCGTACGTCGCGTTCGACGCGCTCGAGCGCGACGCGCTGCGCTGGGACGACAC
CGTCACGGTGGCCGCCGACGACATCGCCTCCGTCGGCCGCGACGAGGCACGCATGTATCTGACGCCCGGGCAGCGCGTTC
GCGTGCGCGACCTGATGCGCGGCCTGATCGTCGCCTCCGCGAACGACGCGGCGCTCGTGCTCGCGAAGCGCATCGGCGGC
AGCCCCGCCGGCTTCGCGACGATGATGAACGACACGGCGCGCCGGCTCGGCATGCGCGATTCGCACTTCGTGTCGCCGTC
CGGCATCACGACGCCCGATCACTATTCGACCGCGCACGACCTGTCGATTCTCGCGCAGCGTCTGAACCGCGATTTCCCGG
CGTTCTACACGTTCTCGTCGCAACGGCATTTCGCGTACGGCGCGTTCGCGAAGACCAACAAGAATCGTCTGCTCGGCGCC
GATCCGAGCGTCGACGGCATGAAGACCGGCCATACGAACGCAGCCGGATGGTGCATGGTCGTCACCGCGAAGCGGCCCGT
CGGCGGCGCGCGCGCGCGGCACCGCGTGATCGCGGTGCTGCTCGGCGAGCCGACCGAGAAGCAGCGGCTCGCCGACGCCC
GCGCGCTCCTCGATCAGGGCTTCGCGTCGCTCGGCGCCGACGCGCCGGCGGCGAACGCCGTGCGACGGGCGAACGCGCGC
CCCGGCGAGCATCGCGCGCAAGCGCGGGCGCGCATGCTCTGA

Upstream 100 bases:

>100_bases
GCCGGCGATTTGCGCTTCGCCGTTCCAGCCGCTTTCGCGAGCCGCCTTCCCGATCCCGCGTCTTCTGCCGTTTTCCATCC
TCTGCATACCTGATTTCCCC

Downstream 100 bases:

>100_bases
CGCCCGCGCGGCGCCGCGTGCGGGCGCGCCGGCGGCGCGACATGCGCGTGCAGTTGTCGCGTTGTCGTTGTCGATGTTGT
CGTCGTCTCGATACCGACGT

Product: peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTTEPLSTTVARGSRRAACALLRTPSRLFASLFVSAACAAPNGARAAPAPAPAIQAASWLVVDADSGKTLGAHNVDARRE
PASLTKLMTAYVAFDALERDALRWDDTVTVAADDIASVGRDEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGG
SPAGFATMMNDTARRLGMRDSHFVSPSGITTPDHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQGFASLGADAPAANAVRRANAR
PGEHRAQARARML

Sequences:

>Translated_333_residues
MTTEPLSTTVARGSRRAACALLRTPSRLFASLFVSAACAAPNGARAAPAPAPAIQAASWLVVDADSGKTLGAHNVDARRE
PASLTKLMTAYVAFDALERDALRWDDTVTVAADDIASVGRDEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGG
SPAGFATMMNDTARRLGMRDSHFVSPSGITTPDHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQGFASLGADAPAANAVRRANAR
PGEHRAQARARML
>Mature_332_residues
TTEPLSTTVARGSRRAACALLRTPSRLFASLFVSAACAAPNGARAAPAPAPAIQAASWLVVDADSGKTLGAHNVDARREP
ASLTKLMTAYVAFDALERDALRWDDTVTVAADDIASVGRDEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGGS
PAGFATMMNDTARRLGMRDSHFVSPSGITTPDHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGAD
PSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQGFASLGADAPAANAVRRANARP
GEHRAQARARML

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=277, Percent_Identity=36.8231046931408, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI87082022, Length=286, Percent_Identity=39.8601398601399, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1786851, Length=273, Percent_Identity=35.5311355311355, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87082054, Length=227, Percent_Identity=30.3964757709251, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 35486; Mature: 35355

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEPLSTTVARGSRRAACALLRTPSRLFASLFVSAACAAPNGARAAPAPAPAIQAASWL
CCCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCEEE
VVDADSGKTLGAHNVDARREPASLTKLMTAYVAFDALERDALRWDDTVTVAADDIASVGR
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
DEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGGSPAGFATMMNDTARRLGMRD
CCCEEEECCCCEEHHHHHHHHHEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
SHFVSPSGITTPDHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
CCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHEECCCCCEECC
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQG
CCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
FASLGADAPAANAVRRANARPGEHRAQARARML
HHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TTEPLSTTVARGSRRAACALLRTPSRLFASLFVSAACAAPNGARAAPAPAPAIQAASWL
CCCCCHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCEEE
VVDADSGKTLGAHNVDARREPASLTKLMTAYVAFDALERDALRWDDTVTVAADDIASVGR
EEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
DEARMYLTPGQRVRVRDLMRGLIVASANDAALVLAKRIGGSPAGFATMMNDTARRLGMRD
CCCEEEECCCCEEHHHHHHHHHEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
SHFVSPSGITTPDHYSTAHDLSILAQRLNRDFPAFYTFSSQRHFAYGAFAKTNKNRLLGA
CCEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHEECCCCCEECC
DPSVDGMKTGHTNAAGWCMVVTAKRPVGGARARHRVIAVLLGEPTEKQRLADARALLDQG
CCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHEEEEEEECCCCHHHHHHHHHHHHHHH
FASLGADAPAANAVRRANARPGEHRAQARARML
HHHHCCCCCHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]