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The map label for this gene is ftsI [H]

Identifier: 76818629

GI number: 76818629

Start: 355141

End: 356988

Strand: Direct

Name: ftsI [H]

Synonym: BURPS1710b_A0239

Alternate gene names: 76818629

Gene position: 355141-356988 (Clockwise)

Preceding gene: 76818571

Following gene: 76818114

Centisome position: 11.16

GC content: 74.24

Gene sequence:

>1848_bases
ATGCGCGTGCCCCGCCGCGACGCACGCACCGGGCACGGCGCCGGGACAGCGATCCGATCGCGCCGCCCCGCGTCACGATC
GCCCGCCGCCGTGCCGATCCGTTCGCCCTCCCGCCATCTCGCCGCTCAACCGACCATGCCGAAACCCGCCGAACCGCTCC
ACCGCCGCCCGCCGCTCACGCCCGCCGCGCTTCCCCGCTGGCGCTCGCGCTGCGTGCTCGCGCTCCTCTGCGCGGGATTC
GGCGCGCTCGCCGCGCGTGCGCTCTGGGTGCAGGTCGTACGCAGCGATTTCTACATCACGCAGGGAATCAAACGATACGG
GCACACGTTCGAAGCCGCCCCCGCACGCGGGCGCATCGTCGATCGCAACGGCGCCGAGCTCGCGATCGACGAGCCCGTCG
CCGACGTTTGGATCGCGCCCGACGCGTTCCGCCGCGCGACGCACGCCCAGATGCGCGCGCTCGCGTCGCTGCTCGGCGTG
CCGATCGACACGCTCGCCGCGAAAGCGCTCGGCACGCGGCAGTTCCTGTACCTGAAGCGCTGGATCGCGCCGGAGCTAGC
CGCTCGCATCGAGCGGCTCGCCGTGCCCGGCGTTCATGTCGCCGCCGCGACGCGGCGCTATTACCCGAGCGGCGGCGACG
CCGCGCAGCTCGTCGGCTTCGTCGGCGCGGACGGCCACGGGCTCGAGGGCGTCGAGCGCACGGCCGACGTCGCGCTCGCC
GGCGTCGGCGCGAAGCGCGACATGATCGTCGACCGGATGGGCCGCCCGGTGCAGGCCGGCGACGCCGCGTCGGCGGGCGT
GCCCGGCGCGGACGTCCGACTGTCGATCGACCGCCGGATCCAGCATCTCGCGCAGCGCGCCGTCGAGCGCGCGGTGGCGC
GCACCGCGGCGGCGGCCGGCTGCGCGATCGTGGTCGACGCGAAGACGGGCGAGATCCTCGCGCTCGTGAACGCGCCCACG
TTCGATCCGAACGAACGCACGGCCGCCGACGACGACGGCCGCTTGCGCGAGCGCGTGCTGACCGACGTCTTCGAGCCGGC
GTCGACGCTCAAGCCCGTCACGGTCGCGCTCGCGCTGAGCGAAGGCGTCGTCGCGCCGGACACGCGCATCGACACGTCGC
CCGGCGTGCTCGACATCGAAGGCGCGACGATTCACGACACCGGCGACTTCGGCGAGCTGACGGTCACGCAGATCATCGCG
AAATCGAGCAACATCGGCATGGCGAAGATCGCCGAGCGGCTGCGCGCGCAGGACATGTGGCGGACGTTCGCGCGCGCGGG
CATCGGCGCGCGGCCGCTCGCCGGCCTGCCGGCCGTCGCCCGCGGCACGCTGCGGCCGGCGCGCAGCTGGAAGCCCATCG
AGCGGCTGACGATGTCCTACGGCTACGGGCTGTCGGTGTCGCTCGCGCAACTCGCGGACGTCTATACGGCGTTCGCCGGC
GACGGCAGCCGGATACCGCTGTCGCTCGCGCATGCGGGCGCGCTGGCCGCGCGGGTGCGCGTCGTGCCGCCCGCGGTCGC
GCGGCAGATCCGCGCGATGCTCGAAACGGACGGCGAAGAAGGCACCGCGCGCATCGCGCGGCTACCCGATTACCGGATCG
GCGCGAAGACCGGCACCGCGCGCAAGCTGTGCGGCAAGCGGTACGCGCGCGGCAAGTACCGGGCGCTCTTCGTCGGCCTC
GCGCCGATGAGCGACCCGCGCCTGATCGTCGCGGTGATGATCGACGAGCCGTCGCGCGGCTCGTACTACGGCGGCCCCGC
GGCGGGGCCCGCATGGGCGGAGATCATGGACAACGCGTTGCATCTGCTCGGCGTGCCGCCCGACCGGCCGGCGGCGCGGC
ACGCCTGA

Upstream 100 bases:

>100_bases
CCCGCGCCGCTCGCGTCGACGCACCGCATCGCCGTTCATCTCTCGCCTGCGGTCGCGCGGCGTCACGCCCCGCGCTGAGG
CGCTTCATCGTGCCCGCCGA

Downstream 100 bases:

>100_bases
CGAGCGGCGGCGCCGGCCGGTCGCCGCTGCGCGGCGGCCGTGGCGCGCCTTGCTGTCTTATCGTCTCGCCGTCTCGCCGT
CGAAGCGTCGAAGCGTCGAA

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBP-2 [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MRVPRRDARTGHGAGTAIRSRRPASRSPAAVPIRSPSRHLAAQPTMPKPAEPLHRRPPLTPAALPRWRSRCVLALLCAGF
GALAARALWVQVVRSDFYITQGIKRYGHTFEAAPARGRIVDRNGAELAIDEPVADVWIAPDAFRRATHAQMRALASLLGV
PIDTLAAKALGTRQFLYLKRWIAPELAARIERLAVPGVHVAAATRRYYPSGGDAAQLVGFVGADGHGLEGVERTADVALA
GVGAKRDMIVDRMGRPVQAGDAASAGVPGADVRLSIDRRIQHLAQRAVERAVARTAAAAGCAIVVDAKTGEILALVNAPT
FDPNERTAADDDGRLRERVLTDVFEPASTLKPVTVALALSEGVVAPDTRIDTSPGVLDIEGATIHDTGDFGELTVTQIIA
KSSNIGMAKIAERLRAQDMWRTFARAGIGARPLAGLPAVARGTLRPARSWKPIERLTMSYGYGLSVSLAQLADVYTAFAG
DGSRIPLSLAHAGALAARVRVVPPAVARQIRAMLETDGEEGTARIARLPDYRIGAKTGTARKLCGKRYARGKYRALFVGL
APMSDPRLIVAVMIDEPSRGSYYGGPAAGPAWAEIMDNALHLLGVPPDRPAARHA

Sequences:

>Translated_615_residues
MRVPRRDARTGHGAGTAIRSRRPASRSPAAVPIRSPSRHLAAQPTMPKPAEPLHRRPPLTPAALPRWRSRCVLALLCAGF
GALAARALWVQVVRSDFYITQGIKRYGHTFEAAPARGRIVDRNGAELAIDEPVADVWIAPDAFRRATHAQMRALASLLGV
PIDTLAAKALGTRQFLYLKRWIAPELAARIERLAVPGVHVAAATRRYYPSGGDAAQLVGFVGADGHGLEGVERTADVALA
GVGAKRDMIVDRMGRPVQAGDAASAGVPGADVRLSIDRRIQHLAQRAVERAVARTAAAAGCAIVVDAKTGEILALVNAPT
FDPNERTAADDDGRLRERVLTDVFEPASTLKPVTVALALSEGVVAPDTRIDTSPGVLDIEGATIHDTGDFGELTVTQIIA
KSSNIGMAKIAERLRAQDMWRTFARAGIGARPLAGLPAVARGTLRPARSWKPIERLTMSYGYGLSVSLAQLADVYTAFAG
DGSRIPLSLAHAGALAARVRVVPPAVARQIRAMLETDGEEGTARIARLPDYRIGAKTGTARKLCGKRYARGKYRALFVGL
APMSDPRLIVAVMIDEPSRGSYYGGPAAGPAWAEIMDNALHLLGVPPDRPAARHA
>Mature_615_residues
MRVPRRDARTGHGAGTAIRSRRPASRSPAAVPIRSPSRHLAAQPTMPKPAEPLHRRPPLTPAALPRWRSRCVLALLCAGF
GALAARALWVQVVRSDFYITQGIKRYGHTFEAAPARGRIVDRNGAELAIDEPVADVWIAPDAFRRATHAQMRALASLLGV
PIDTLAAKALGTRQFLYLKRWIAPELAARIERLAVPGVHVAAATRRYYPSGGDAAQLVGFVGADGHGLEGVERTADVALA
GVGAKRDMIVDRMGRPVQAGDAASAGVPGADVRLSIDRRIQHLAQRAVERAVARTAAAAGCAIVVDAKTGEILALVNAPT
FDPNERTAADDDGRLRERVLTDVFEPASTLKPVTVALALSEGVVAPDTRIDTSPGVLDIEGATIHDTGDFGELTVTQIIA
KSSNIGMAKIAERLRAQDMWRTFARAGIGARPLAGLPAVARGTLRPARSWKPIERLTMSYGYGLSVSLAQLADVYTAFAG
DGSRIPLSLAHAGALAARVRVVPPAVARQIRAMLETDGEEGTARIARLPDYRIGAKTGTARKLCGKRYARGKYRALFVGL
APMSDPRLIVAVMIDEPSRGSYYGGPAAGPAWAEIMDNALHLLGVPPDRPAARHA

Specific function: Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=555, Percent_Identity=35.8558558558559, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI1786854, Length=617, Percent_Identity=24.9594813614263, Blast_Score=115, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65440; Mature: 65440

Theoretical pI: Translated: 10.92; Mature: 10.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPRRDARTGHGAGTAIRSRRPASRSPAAVPIRSPSRHLAAQPTMPKPAEPLHRRPPLT
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHCCCCCC
PAALPRWRSRCVLALLCAGFGALAARALWVQVVRSDFYITQGIKRYGHTFEAAPARGRIV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEE
DRNGAELAIDEPVADVWIAPDAFRRATHAQMRALASLLGVPIDTLAAKALGTRQFLYLKR
ECCCCEEEECCCCHHEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHH
WIAPELAARIERLAVPGVHVAAATRRYYPSGGDAAQLVGFVGADGHGLEGVERTADVALA
HHCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHEEECCCCCCCCCHHHHHHHHEE
GVGAKRDMIVDRMGRPVQAGDAASAGVPGADVRLSIDRRIQHLAQRAVERAVARTAAAAG
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
CAIVVDAKTGEILALVNAPTFDPNERTAADDDGRLRERVLTDVFEPASTLKPVTVALALS
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEEEEEC
EGVVAPDTRIDTSPGVLDIEGATIHDTGDFGELTVTQIIAKSSNIGMAKIAERLRAQDMW
CCCCCCCCCCCCCCCEEEECCCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RTFARAGIGARPLAGLPAVARGTLRPARSWKPIERLTMSYGYGLSVSLAQLADVYTAFAG
HHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DGSRIPLSLAHAGALAARVRVVPPAVARQIRAMLETDGEEGTARIARLPDYRIGAKTGTA
CCCCCCCHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHH
RKLCGKRYARGKYRALFVGLAPMSDPRLIVAVMIDEPSRGSYYGGPAAGPAWAEIMDNAL
HHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
HLLGVPPDRPAARHA
HEECCCCCCCCCCCC
>Mature Secondary Structure
MRVPRRDARTGHGAGTAIRSRRPASRSPAAVPIRSPSRHLAAQPTMPKPAEPLHRRPPLT
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHCCCCCC
PAALPRWRSRCVLALLCAGFGALAARALWVQVVRSDFYITQGIKRYGHTFEAAPARGRIV
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEE
DRNGAELAIDEPVADVWIAPDAFRRATHAQMRALASLLGVPIDTLAAKALGTRQFLYLKR
ECCCCEEEECCCCHHEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHH
WIAPELAARIERLAVPGVHVAAATRRYYPSGGDAAQLVGFVGADGHGLEGVERTADVALA
HHCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHEEECCCCCCCCCHHHHHHHHEE
GVGAKRDMIVDRMGRPVQAGDAASAGVPGADVRLSIDRRIQHLAQRAVERAVARTAAAAG
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
CAIVVDAKTGEILALVNAPTFDPNERTAADDDGRLRERVLTDVFEPASTLKPVTVALALS
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEEEEEC
EGVVAPDTRIDTSPGVLDIEGATIHDTGDFGELTVTQIIAKSSNIGMAKIAERLRAQDMW
CCCCCCCCCCCCCCCEEEECCCEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RTFARAGIGARPLAGLPAVARGTLRPARSWKPIERLTMSYGYGLSVSLAQLADVYTAFAG
HHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DGSRIPLSLAHAGALAARVRVVPPAVARQIRAMLETDGEEGTARIARLPDYRIGAKTGTA
CCCCCCCHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHH
RKLCGKRYARGKYRALFVGLAPMSDPRLIVAVMIDEPSRGSYYGGPAAGPAWAEIMDNAL
HHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
HLLGVPPDRPAARHA
HEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3126399 [H]