| Definition | Burkholderia pseudomallei 1710b chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_007435 |
| Length | 3,181,762 |
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The map label for this gene is nrdA [H]
Identifier: 76818467
GI number: 76818467
Start: 2469269
End: 2471884
Strand: Direct
Name: nrdA [H]
Synonym: BURPS1710b_A2032
Alternate gene names: 76818467
Gene position: 2469269-2471884 (Clockwise)
Preceding gene: 76819196
Following gene: 76817725
Centisome position: 77.61
GC content: 69.0
Gene sequence:
>2616_bases GTGAGCCGCTCTCGGCCGCCATGCCCTGCGGCTATCGGGCCGAGCCCATCATTCACGCGCAATGCCGTAGAGAGGCTGTC CATGGCGACCATCGCAACCGAGTTCCACTTCGCTGCGCAACAATTCTCGATCGACGTGCTGCTGGAGAAATACGCGAAGG GCGAGGAGCGAACGGTCGACGACATCTATCGCCGCGTCGCGCGCGGCGTCGCGCAGGCGGAGCCGCCCGAATTGCGCGAC GAAATCGAGGCGCGCTTCGTCGAGCATCTGCAACGCGGCGCGCTCGGCGCCGGCCGGATCATGAGCGCGGCGGGCAGCCC GATCGCGGCGACGCTGATCAACTGCTTCGTGCAGCCGGTCGGCGATTGCATCCAGGGCGTCGACGAGCGTGGGCTGCCCG GCATCTATGTCGCGCTGCTGCAGGCGGCGGAGACGATGCGGCGCGGCGGCGGGGTCGGCTACAACTTCTCCGCGATCCGG CCGCGCGGCGCATACGTGCATTCGACGGGCTCGAGCGCGTCCGGGCCGTGCAGCTACATCGACGTGTTCGACGCGTCGTG CCGCACGGTCGAGAGCGCGGGCGCGCGGCGCGGCGCGCAGATGGCGGTGCTCGACTGCGATCACCCGGACCTGCTCGAAT TCATCGAGGCGAAGCATTCGAAGGGCCGCTGGAACAACTTCAACATCTCGGTCGCGGTGACCGACGCGTTCATGAACGCG GTCGAGCAGGACTTGCCGTGGCAGCTCGTGCATCGCGCGGAGCCGTCGCCCGCGCTGCGCGCGGCCGGCGATCTGCGGCG GCGCGACGACGGGATGTGGGTCTACGCCGAGCGGCGCGCGCGCGCGATCTGGGAGAAGATCATGCGCTCGACGTACGACG TCGCCGAGCCGGGCGTCGTGTTCATCTCGAAGATGAACGACGACAACAACCTGCGCGCGATCGAATCGATTCGCGCGACG AACCCGTGCGGCGAGCAGCCGCTGCCCGCGTACGGCTGCTGCAATCTCGGGCCGCTGAACCTCACGCGCTTCGTGATCGA TCCGTTCGCGGAGCTGACCGGCGGCGAAAGCGCGTTCGACTGGCGCGCGCTCGCCGAGCGCACGCGCACGCAGGTGCGCT TTCTCGACGACGTGCTCGACGTGACGCTCTGGCCGCTGCCCGAGCAGCGCCACGAGGCGCAGCAGAAGCGGCGGATCGGC ATCGGCTTCACGGGCCTCGGCGACACGCTCGTGATGCTCGGCCTGCGCTACGACTCGCAGCAGGGGCGCGACTTCGCCGC GCGCGTCGGGCGCGAGATGCGCGACGCCGCGTATCGCGCGTCGGTCGAGCTCGCGCGCGAGCGCGGCGCGTTTGCGCTGT TCGACGCGAACCGGTATCTCGAAGAAGGCACGTTCGCGTCGCGGCTGCCCGAGGACATTCGCGAGGCGATCCGCCGCGAC GGCATCCGCAACAGCCACCTGCTGTCGATCGCGCCGACGGGCACCGTGAGCCTCGCGTTCGCGGACAATGCGTCGAACGG CATCGAGCCCGCGTTCTCGTGGACCTATCAGCGCACGAAGATCATGGCCGACGGCAGCCGGCAGACGTTCGCCGTCGAGG ATTACGCGTACCGGCTGTATCGCGAGCTGGGCGGCGACGTCGGCGCGCTGCCCGCCTGTTTCGTGAGCGCGCTGCAGATG TCCGCGCACGACCACCTCGCGATGATGGCGGCCGTGCAGCCGTACATCGACACGTCGATCTCGAAGACGGTCAACGTGCC CGCCGACTATCCGTTCGACGATTTCGAGAGCCTCTACTTCGACGCGTGGAAGAGCGGGCTGAAAGGGCTCGCGACGTATC GCCCGAACGAGACGCTCGGCGCGGTGCTCCACACGTCCGAGCCCGACGACGCGCTCGAGGAGGCGGATCTCGATCCGCTG CGGATCGCGATCGACCACCGGCCGAAGGGGGAACTGCCGGCGGTGATCGAGAAGGTCGAATACCTGACGCAGCTCGGCAA GAAATCGCTATATGTCGCGGTGTCGTTCATGGAGGTGACGGGGCGCATCGGCGGCGACGAAGTGACGATCGAGCGGCCGA TCGAATTCTTCATTCCGGTCGGCCAGCGCGACGAATCGCAGCAATGGATCACGGCGACGATGCGTTCGCTGTCGCTTGCC GCGCGCGGCGGCTTCGTCGCGCGCAATCTGCAGGATCTGCGCAAGGTGTCGTGGGACCGCGGGCAGGTGCGGCTCGGCGA GACGCAGCGGCTCGACGGCCGGCGCATTCCGCTGTGGCACGATTCCGAAGTCGCCGCGCTCAGCTATGCGATCCAGCAGA TCCTGCATCGTCGCGGCTTTCTCGACGCGGAAGGCAACCAGGTGCCGTCGCGGCTGCTCGCGAAGCTGCCGCGCGGCGGC GCGGACTCGCACGCGGTTGCCGCGCTGCTCGCGGCCGAAGCCGGATCGGCGGGCGGCGAAGGTGACGAAGAGACGGCGGC GGCGCGCGGCGCCGGCGCCGGCGAGCTGCGCACGATGTTCGGCCGCAAGTGCAATTCGTGCGGCGCGAACGCGGTGATTC GCAAGGACGGCTGCGATTTCTGCACCGCGTGCGGCGAGATCGGCGCGTGCGGGTAG
Upstream 100 bases:
>100_bases CGGTGTTCCGTTTCATTGACCCGGCCGTGGTTTCGCGCGATCGGCGCGCGCCGCCCGATTGCGGGGAAAGGGCGGCTGCG GTAAGGTCCTCGCATGCGGC
Downstream 100 bases:
>100_bases GCACGCGCGTGCTCGTTCGCGCATGTGCGCGCAGCCGGCGGCGCACGCATGTGCGCGTCGGCGCGGCGGCCGGGCCGGCG GTTCGATGCGGCGCACGCCG
Product: ribonucleotide reductase, coenzyme B12-dependent
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 871; Mature: 870
Protein sequence:
>871_residues MSRSRPPCPAAIGPSPSFTRNAVERLSMATIATEFHFAAQQFSIDVLLEKYAKGEERTVDDIYRRVARGVAQAEPPELRD EIEARFVEHLQRGALGAGRIMSAAGSPIAATLINCFVQPVGDCIQGVDERGLPGIYVALLQAAETMRRGGGVGYNFSAIR PRGAYVHSTGSSASGPCSYIDVFDASCRTVESAGARRGAQMAVLDCDHPDLLEFIEAKHSKGRWNNFNISVAVTDAFMNA VEQDLPWQLVHRAEPSPALRAAGDLRRRDDGMWVYAERRARAIWEKIMRSTYDVAEPGVVFISKMNDDNNLRAIESIRAT NPCGEQPLPAYGCCNLGPLNLTRFVIDPFAELTGGESAFDWRALAERTRTQVRFLDDVLDVTLWPLPEQRHEAQQKRRIG IGFTGLGDTLVMLGLRYDSQQGRDFAARVGREMRDAAYRASVELARERGAFALFDANRYLEEGTFASRLPEDIREAIRRD GIRNSHLLSIAPTGTVSLAFADNASNGIEPAFSWTYQRTKIMADGSRQTFAVEDYAYRLYRELGGDVGALPACFVSALQM SAHDHLAMMAAVQPYIDTSISKTVNVPADYPFDDFESLYFDAWKSGLKGLATYRPNETLGAVLHTSEPDDALEEADLDPL RIAIDHRPKGELPAVIEKVEYLTQLGKKSLYVAVSFMEVTGRIGGDEVTIERPIEFFIPVGQRDESQQWITATMRSLSLA ARGGFVARNLQDLRKVSWDRGQVRLGETQRLDGRRIPLWHDSEVAALSYAIQQILHRRGFLDAEGNQVPSRLLAKLPRGG ADSHAVAALLAAEAGSAGGEGDEETAAARGAGAGELRTMFGRKCNSCGANAVIRKDGCDFCTACGEIGACG
Sequences:
>Translated_871_residues MSRSRPPCPAAIGPSPSFTRNAVERLSMATIATEFHFAAQQFSIDVLLEKYAKGEERTVDDIYRRVARGVAQAEPPELRD EIEARFVEHLQRGALGAGRIMSAAGSPIAATLINCFVQPVGDCIQGVDERGLPGIYVALLQAAETMRRGGGVGYNFSAIR PRGAYVHSTGSSASGPCSYIDVFDASCRTVESAGARRGAQMAVLDCDHPDLLEFIEAKHSKGRWNNFNISVAVTDAFMNA VEQDLPWQLVHRAEPSPALRAAGDLRRRDDGMWVYAERRARAIWEKIMRSTYDVAEPGVVFISKMNDDNNLRAIESIRAT NPCGEQPLPAYGCCNLGPLNLTRFVIDPFAELTGGESAFDWRALAERTRTQVRFLDDVLDVTLWPLPEQRHEAQQKRRIG IGFTGLGDTLVMLGLRYDSQQGRDFAARVGREMRDAAYRASVELARERGAFALFDANRYLEEGTFASRLPEDIREAIRRD GIRNSHLLSIAPTGTVSLAFADNASNGIEPAFSWTYQRTKIMADGSRQTFAVEDYAYRLYRELGGDVGALPACFVSALQM SAHDHLAMMAAVQPYIDTSISKTVNVPADYPFDDFESLYFDAWKSGLKGLATYRPNETLGAVLHTSEPDDALEEADLDPL RIAIDHRPKGELPAVIEKVEYLTQLGKKSLYVAVSFMEVTGRIGGDEVTIERPIEFFIPVGQRDESQQWITATMRSLSLA ARGGFVARNLQDLRKVSWDRGQVRLGETQRLDGRRIPLWHDSEVAALSYAIQQILHRRGFLDAEGNQVPSRLLAKLPRGG ADSHAVAALLAAEAGSAGGEGDEETAAARGAGAGELRTMFGRKCNSCGANAVIRKDGCDFCTACGEIGACG >Mature_870_residues SRSRPPCPAAIGPSPSFTRNAVERLSMATIATEFHFAAQQFSIDVLLEKYAKGEERTVDDIYRRVARGVAQAEPPELRDE IEARFVEHLQRGALGAGRIMSAAGSPIAATLINCFVQPVGDCIQGVDERGLPGIYVALLQAAETMRRGGGVGYNFSAIRP RGAYVHSTGSSASGPCSYIDVFDASCRTVESAGARRGAQMAVLDCDHPDLLEFIEAKHSKGRWNNFNISVAVTDAFMNAV EQDLPWQLVHRAEPSPALRAAGDLRRRDDGMWVYAERRARAIWEKIMRSTYDVAEPGVVFISKMNDDNNLRAIESIRATN PCGEQPLPAYGCCNLGPLNLTRFVIDPFAELTGGESAFDWRALAERTRTQVRFLDDVLDVTLWPLPEQRHEAQQKRRIGI GFTGLGDTLVMLGLRYDSQQGRDFAARVGREMRDAAYRASVELARERGAFALFDANRYLEEGTFASRLPEDIREAIRRDG IRNSHLLSIAPTGTVSLAFADNASNGIEPAFSWTYQRTKIMADGSRQTFAVEDYAYRLYRELGGDVGALPACFVSALQMS AHDHLAMMAAVQPYIDTSISKTVNVPADYPFDDFESLYFDAWKSGLKGLATYRPNETLGAVLHTSEPDDALEEADLDPLR IAIDHRPKGELPAVIEKVEYLTQLGKKSLYVAVSFMEVTGRIGGDEVTIERPIEFFIPVGQRDESQQWITATMRSLSLAA RGGFVARNLQDLRKVSWDRGQVRLGETQRLDGRRIPLWHDSEVAALSYAIQQILHRRGFLDAEGNQVPSRLLAKLPRGGA DSHAVAALLAAEAGSAGGEGDEETAAARGAGAGELRTMFGRKCNSCGANAVIRKDGCDFCTACGEIGACG
Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]
COG id: COG0209
COG function: function code F; Ribonucleotide reductase, alpha subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-cone domain [H]
Homologues:
Organism=Homo sapiens, GI4506749, Length=549, Percent_Identity=24.408014571949, Blast_Score=160, Evalue=4e-39, Organism=Escherichia coli, GI1789030, Length=578, Percent_Identity=22.6643598615917, Blast_Score=96, Evalue=9e-21, Organism=Escherichia coli, GI2367133, Length=645, Percent_Identity=24.8062015503876, Blast_Score=89, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17555242, Length=588, Percent_Identity=25.6802721088435, Blast_Score=172, Evalue=8e-43, Organism=Saccharomyces cerevisiae, GI6322123, Length=557, Percent_Identity=25.673249551167, Blast_Score=152, Evalue=2e-37, Organism=Saccharomyces cerevisiae, GI6320914, Length=591, Percent_Identity=25.0423011844332, Blast_Score=148, Evalue=4e-36, Organism=Drosophila melanogaster, GI17352481, Length=541, Percent_Identity=24.0295748613678, Blast_Score=157, Evalue=2e-38,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005144 - InterPro: IPR013344 - InterPro: IPR013509 - InterPro: IPR000788 - InterPro: IPR008926 [H]
Pfam domain/function: PF03477 ATP-cone; PF02867 Ribonuc_red_lgC; PF00317 Ribonuc_red_lgN [H]
EC number: =1.17.4.1 [H]
Molecular weight: Translated: 95489; Mature: 95358
Theoretical pI: Translated: 5.62; Mature: 5.62
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRSRPPCPAAIGPSPSFTRNAVERLSMATIATEFHFAAQQFSIDVLLEKYAKGEERTVD CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH DIYRRVARGVAQAEPPELRDEIEARFVEHLQRGALGAGRIMSAAGSPIAATLINCFVQPV HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHH GDCIQGVDERGLPGIYVALLQAAETMRRGGGVGYNFSAIRPRGAYVHSTGSSASGPCSYI HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCH DVFDASCRTVESAGARRGAQMAVLDCDHPDLLEFIEAKHSKGRWNNFNISVAVTDAFMNA HHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHH VEQDLPWQLVHRAEPSPALRAAGDLRRRDDGMWVYAERRARAIWEKIMRSTYDVAEPGVV HHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEE FISKMNDDNNLRAIESIRATNPCGEQPLPAYGCCNLGPLNLTRFVIDPFAELTGGESAFD EEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH WRALAERTRTQVRFLDDVLDVTLWPLPEQRHEAQQKRRIGIGFTGLGDTLVMLGLRYDSQ HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCC QGRDFAARVGREMRDAAYRASVELARERGAFALFDANRYLEEGTFASRLPEDIREAIRRD CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHCCCHHHHCCHHHHHHHHHC GIRNSHLLSIAPTGTVSLAFADNASNGIEPAFSWTYQRTKIMADGSRQTFAVEDYAYRLY CCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHEEEEECCCCCEEEHHHHHHHHH RELGGDVGALPACFVSALQMSAHDHLAMMAAVQPYIDTSISKTVNVPADYPFDDFESLYF HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHH DAWKSGLKGLATYRPNETLGAVLHTSEPDDALEEADLDPLRIAIDHRPKGELPAVIEKVE HHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH YLTQLGKKSLYVAVSFMEVTGRIGGDEVTIERPIEFFIPVGQRDESQQWITATMRSLSLA HHHHHCCCCEEEEEEEHHHHCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHH ARGGFVARNLQDLRKVSWDRGQVRLGETQRLDGRRIPLWHDSEVAALSYAIQQILHRRGF HCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC LDAEGNQVPSRLLAKLPRGGADSHAVAALLAAEAGSAGGEGDEETAAARGAGAGELRTMF CCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHH GRKCNSCGANAVIRKDGCDFCTACGEIGACG CCCCCCCCCCCEEECCCCHHHHHHCCCCCCC >Mature Secondary Structure SRSRPPCPAAIGPSPSFTRNAVERLSMATIATEFHFAAQQFSIDVLLEKYAKGEERTVD CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH DIYRRVARGVAQAEPPELRDEIEARFVEHLQRGALGAGRIMSAAGSPIAATLINCFVQPV HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHH GDCIQGVDERGLPGIYVALLQAAETMRRGGGVGYNFSAIRPRGAYVHSTGSSASGPCSYI HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCH DVFDASCRTVESAGARRGAQMAVLDCDHPDLLEFIEAKHSKGRWNNFNISVAVTDAFMNA HHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHH VEQDLPWQLVHRAEPSPALRAAGDLRRRDDGMWVYAERRARAIWEKIMRSTYDVAEPGVV HHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEE FISKMNDDNNLRAIESIRATNPCGEQPLPAYGCCNLGPLNLTRFVIDPFAELTGGESAFD EEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH WRALAERTRTQVRFLDDVLDVTLWPLPEQRHEAQQKRRIGIGFTGLGDTLVMLGLRYDSQ HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCC QGRDFAARVGREMRDAAYRASVELARERGAFALFDANRYLEEGTFASRLPEDIREAIRRD CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHCCCHHHHCCHHHHHHHHHC GIRNSHLLSIAPTGTVSLAFADNASNGIEPAFSWTYQRTKIMADGSRQTFAVEDYAYRLY CCCCCCEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHEEEEECCCCCEEEHHHHHHHHH RELGGDVGALPACFVSALQMSAHDHLAMMAAVQPYIDTSISKTVNVPADYPFDDFESLYF HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHH DAWKSGLKGLATYRPNETLGAVLHTSEPDDALEEADLDPLRIAIDHRPKGELPAVIEKVE HHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH YLTQLGKKSLYVAVSFMEVTGRIGGDEVTIERPIEFFIPVGQRDESQQWITATMRSLSLA HHHHHCCCCEEEEEEEHHHHCCCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHH ARGGFVARNLQDLRKVSWDRGQVRLGETQRLDGRRIPLWHDSEVAALSYAIQQILHRRGF HCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC LDAEGNQVPSRLLAKLPRGGADSHAVAALLAAEAGSAGGEGDEETAAARGAGAGELRTMF CCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHHH GRKCNSCGANAVIRKDGCDFCTACGEIGACG CCCCCCCCCCCEEECCCCHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]