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The map label for this gene is noxB [C]

Identifier: 76817863

GI number: 76817863

Start: 811970

End: 813295

Strand: Direct

Name: noxB [C]

Synonym: BURPS1710b_A0619

Alternate gene names: 76817863

Gene position: 811970-813295 (Clockwise)

Preceding gene: 76819605

Following gene: 76819379

Centisome position: 25.52

GC content: 68.48

Gene sequence:

>1326_bases
ATGCCCGATTCGAATCCCACCGCGGCCGCGTTGCTCGCGCAGCCGCTCACGCTGCCGAACGGCACCGTGCTGAAGAACCG
CCTCGCGAAATCGGCGCTGAGCGAAGCGCTGTGCGGGCACGACGGCCGTGTGACGCCGCAGCTGATCGCGCTGTACCGGC
GCTGGTCGGGTTCGGGCGCGGGGCTGCTCGTCACCGGCAACGTGATGATCGACGGCAAGGCGCTCGGCGAGCCCGGCAAC
GTCGTGATCGAGGACGACCGCGATCTGCCGCGTCTGCGCGAATGGGCCGCGGCCGCGAAAGCGCACGGCAGCGAGATCTG
GATGCAGATCAATCATCCCGGCAAGCAGGCGATGCGCGGACTCAACGAGGAAACCGTCGCGCCGTCGGCGATCGGCTTCG
GGCCGAAGCTTTCGCCGTATTTCGCGGTGCCGCGCGCGCTGACGGTGGACGAGATCGACGCGCTGATCCGGCGCTACGGA
ACGACGGCCGCCGTCGCGCAGCAGGCGGGCTTCACCGGCGTGCAGTTGCACGGCGCGCACGGCTATCTGATCAACCAGTT
CCTGTCGCCGCAGCACAATCAGCGCACCGACGAATGGGGCGGCAGCGCGGAGAACCGCCGGCGCTTCGTGCTCGCGGTGT
ACGCGGAAGTGCGGCGCCGGGTGGGCCCCGATTTTCCGATCGGCATCAAGCTCAATTCGGCCGATTTCCAGCGCGGCGGC
TTCACCGAGGAAGAATCGCTCGACGTGATCCGCGCGCTCGCCGAGGCGGGCATCGATCTGATCGAGATTTCCGGCGGCAC
CTACGAAACGCCCGTGATGCAGCTCGGCGACCGCAAGGCGTCGACGATCGCGCGTGAAGCGTACTTCCTCGCGTTCGCCG
AGAAGGTGCGCGCGGACGTGAAGGTGCCGTTGATGGTCACGGGCGGCTTTCGCAGCCTCGCCGGCATGGAGGCGCCGCTG
CGCGACGGCGCGCTCGACCTGATCGGCCTCGGGCGTATCCTCGCGATCGAGCCCGACGCGCCCGCGCGCCTGCTGCGCGG
CGAGGAAACGCGCCATCGCGTGAAGCCGCTCAGCACGGGCGTCAAATACTTCGACAGCCTCGGTTCGCTCGAAGTCACGT
GGTATACGCGGCAGCTCCATCGAATCGGCAAGGGGCGCAATCCGATTCCCGACGAGAATGCGCTGAAATCGTTCCTGCTC
GACCTGTCGTCGAAGGGCTGCGCGATCTTCAAGGCGCGTCGCCTGCGTGCTTCGTCCTCCGAAGCGTCGGCCGCGCGGGG
TTCGGCGACGTCGGTCGCCGGCGGCCCGCGGCACGATGCGCATTGA

Upstream 100 bases:

>100_bases
CTCAGTTCCGATTTTGAACTTACGATCCCAACCAATACATCAATCGATGTAACATTACTCGATGGATTTTCGGTCGTCGA
CCCAACCGGAGCGTCATGCC

Downstream 100 bases:

>100_bases
GCGGAGCGACCCGCCTCGCGCAACGGCGCCGCCCGGCCGAGTAAACGCCGCGCGGCGCGCGGCATCGGCGCATCGAATGC
GCTTTGCTCGATGCTTCGCG

Product: oxidoreductase, FAD/FMN-binding

Products: trans-transtetradehydroacyl-CoA; NADPH [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVTPQLIALYRRWSGSGAGLLVTGNVMIDGKALGEPGN
VVIEDDRDLPRLREWAAAAKAHGSEIWMQINHPGKQAMRGLNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYG
TTAAVAQQAGFTGVQLHGAHGYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVGPDFPIGIKLNSADFQRGG
FTEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKASTIAREAYFLAFAEKVRADVKVPLMVTGGFRSLAGMEAPL
RDGALDLIGLGRILAIEPDAPARLLRGEETRHRVKPLSTGVKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFLL
DLSSKGCAIFKARRLRASSSEASAARGSATSVAGGPRHDAH

Sequences:

>Translated_441_residues
MPDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVTPQLIALYRRWSGSGAGLLVTGNVMIDGKALGEPGN
VVIEDDRDLPRLREWAAAAKAHGSEIWMQINHPGKQAMRGLNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYG
TTAAVAQQAGFTGVQLHGAHGYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVGPDFPIGIKLNSADFQRGG
FTEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKASTIAREAYFLAFAEKVRADVKVPLMVTGGFRSLAGMEAPL
RDGALDLIGLGRILAIEPDAPARLLRGEETRHRVKPLSTGVKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFLL
DLSSKGCAIFKARRLRASSSEASAARGSATSVAGGPRHDAH
>Mature_440_residues
PDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVTPQLIALYRRWSGSGAGLLVTGNVMIDGKALGEPGNV
VIEDDRDLPRLREWAAAAKAHGSEIWMQINHPGKQAMRGLNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYGT
TAAVAQQAGFTGVQLHGAHGYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVGPDFPIGIKLNSADFQRGGF
TEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKASTIAREAYFLAFAEKVRADVKVPLMVTGGFRSLAGMEAPLR
DGALDLIGLGRILAIEPDAPARLLRGEETRHRVKPLSTGVKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFLLD
LSSKGCAIFKARRLRASSSEASAARGSATSVAGGPRHDAH

Specific function: Reduces a range of alternative electron acceptors [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=312, Percent_Identity=31.4102564102564, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787939, Length=341, Percent_Identity=31.0850439882698, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17565138, Length=360, Percent_Identity=38.0555555555556, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17540738, Length=367, Percent_Identity=36.2397820163488, Blast_Score=221, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI17559802, Length=361, Percent_Identity=35.1800554016621, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17564188, Length=364, Percent_Identity=33.7912087912088, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17559804, Length=365, Percent_Identity=33.1506849315069, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17566914, Length=355, Percent_Identity=34.3661971830986, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI72001454, Length=359, Percent_Identity=34.2618384401114, Blast_Score=198, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17566916, Length=366, Percent_Identity=34.1530054644809, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321973, Length=87, Percent_Identity=45.9770114942529, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=88, Percent_Identity=44.3181818181818, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR016040
- InterPro:   IPR001155
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: 1.3.1.34 [C]

Molecular weight: Translated: 47567; Mature: 47436

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVTPQLIALYRRWSGSGA
CCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
GLLVTGNVMIDGKALGEPGNVVIEDDRDLPRLREWAAAAKAHGSEIWMQINHPGKQAMRG
EEEEECCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHCC
LNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYGTTAAVAQQAGFTGVQLHGAH
CCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCC
GYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVGPDFPIGIKLNSADFQRGG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCC
FTEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKASTIAREAYFLAFAEKVRADV
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
KVPLMVTGGFRSLAGMEAPLRDGALDLIGLGRILAIEPDAPARLLRGEETRHRVKPLSTG
EEEEEEECCCHHHHCCCCCCCCCCEEEEECCEEEEECCCCCHHHHCCCHHHHHHHHHHHH
VKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFLLDLSSKGCAIFKARRLRASSS
HHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHCCCC
EASAARGSATSVAGGPRHDAH
HHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDSNPTAAALLAQPLTLPNGTVLKNRLAKSALSEALCGHDGRVTPQLIALYRRWSGSGA
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
GLLVTGNVMIDGKALGEPGNVVIEDDRDLPRLREWAAAAKAHGSEIWMQINHPGKQAMRG
EEEEECCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHCC
LNEETVAPSAIGFGPKLSPYFAVPRALTVDEIDALIRRYGTTAAVAQQAGFTGVQLHGAH
CCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECCC
GYLINQFLSPQHNQRTDEWGGSAENRRRFVLAVYAEVRRRVGPDFPIGIKLNSADFQRGG
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEEEEECCCCCCCCC
FTEEESLDVIRALAEAGIDLIEISGGTYETPVMQLGDRKASTIAREAYFLAFAEKVRADV
CCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
KVPLMVTGGFRSLAGMEAPLRDGALDLIGLGRILAIEPDAPARLLRGEETRHRVKPLSTG
EEEEEEECCCHHHHCCCCCCCCCCEEEEECCEEEEECCCCCHHHHCCCHHHHHHHHHHHH
VKYFDSLGSLEVTWYTRQLHRIGKGRNPIPDENALKSFLLDLSSKGCAIFKARRLRASSS
HHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEHHHHHHHCCCC
EASAARGSATSVAGGPRHDAH
HHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FAD. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: transDidehydroacyl-CoA; NADP+ [C]

Specific reaction: transDidehydroacyl-CoA + NADP+ =trans-transtetradehydroacyl-CoA + NADPH [C]

General reaction: Redox reaction [C]

Inhibitor: Iodoacetic acid; N-Ethyl maleimide [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8357835 [H]