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The map label for this gene is ppsA [H]

Identifier: 75910045

GI number: 75910045

Start: 4781195

End: 4783654

Strand: Direct

Name: ppsA [H]

Synonym: Ava_3841

Alternate gene names: 75910045

Gene position: 4781195-4783654 (Clockwise)

Preceding gene: 75910041

Following gene: 75910048

Centisome position: 75.11

GC content: 44.88

Gene sequence:

>2460_bases
ATGGTGACAGTATCTCAAAACACTTTAGCAAAATGTTCTCAAGAGGAATCGCTGGTTCTCTGGCTTGATAAAGTTGGCAT
TAAAGATATTGCCTTAGTGGGGGGTAAAAATGCCTCATTGGGGGAAATGATTCAACAACTGACACCCAAAGGTGTGAACG
TACCGACAGGATTTGCTACTACTGCTTACGCTTATCGTTATTTCATCCAATCGGCTGGGTTAGAAGCCAAGTTACGGGAA
CTGTTTGCAGATTTGGATGTGGAGGATGTGAGAAATTTACAAGAAAGGGGACTAAAAGCGCGATCGCTCCTCATGCACAC
CCCATTTCCTGTAGAATTACAACAGGCGATCGCCTCTGCTTATGAAAGTTTGTGTAAGCAGTACAACCCTGATACAGATG
TCGCCGTCCGTTCCAGCGCTACCGCCGAAGACTTACCAGATGCGAGTTTTGCTGGACAACAAGAAACTTATCTCAATGTA
GTTGGCGCAGAAGAAGTATTAGCAGCTTGTCATAAATGCTTTGCTTCCCTATTTACAGACCGCGCCATTTCCTATCGCCA
TACTAAAGGATTTGATCACTTTAGCGTCGCCTTGGCTGTGGGTGTGCAGAAAATGGTACGTTCTGACCTAGCCACCTCTG
GGGTGATGTTCTCTATTGACACAGAAACGGGTTTTAAAGATGCAGCCTTAATTACAGCCGCCTATGGTTTAGGTGAAAAT
GTTGTTCAAGGCGCAGTTAATCCAGATGAATATTGTGTATTTAAGCCGACATTAAAAGCAGGATTTAAACCAATTATTGA
TAAAAAATTGGGCAGTAAAGAATTAAGAATGGTCTATGATGAAGGCTCCCAATCTACTAAAAATGAAGCAGTATCAATAG
TAGAACAAAATCAATTTGCTCTCAATGACGCAGACATTTTACAACTGGCTCATTGGGCTTGTTTAATTGAAGACCATTAT
TCTCAAGCCCACGGTAGTTACACCCCAATGGATATTGAATGGGCGAAAGATGGCATCACCAACCAACTTTTTGTAGTGCA
AGCACGGCCAGAAACGGTGCAGTCCCAGAAGAATGGTAACGTGTTGCGGAGTTACCGCTTGGGGCTGGGGACTGGGGAGA
AAACACAAAATATATCACTCCTCCCTCTTGTTACTGGACGCGCTATTGGTGAAGCCATTAGCCAGGGGAAAGCGCGGGTA
ATTTTAGATGCCAAACAAATAGAAGAATTTCAGGCTGGGGAAGTGTTGGTGACGGAGAGAACTGACCCTGACTGGGAACC
AATTATGAAACGTGCCAGTGCAATTATTACCAATTCTGGTGGTCGTACTTGTCATGCGGCAATTATCGCACGGGAATTGG
GTGTGCCGGCGATCGTTGGCTGTGGTAATGCCACGCAAGTTTTAACAACTGGTCAAGAGGTGACGGTTTCTTGTGCGGAG
GGTGAAGAAGGTAAAGTTTATCCTGGGTTATTACCTTTTGAAGTTAAAGAAGTTCCCTTAGAAAACTTACCCCGCACCCA
TACCCAAATCTTGATGAATGTGGGTAATCCCCAAGAAGCGTTTAGTTTATCGGCAATTCCCAATGACGGTGTTGGTTTAG
CCAGGACAGAGTTTATTATTGCTAACCAAATTCAAGTTCATCCCTTGGCATTGATTCACTACGACAAATTAGCGGATGCA
GAACAAAAAGCTAAAGTTGCGGCTATCACCGCCACGTATGAGGATAAACCCCAATATTTCGTCGATAAATTAGCCCAAGG
TGTGGGCAGAATTGCCGCCGCCTTTTATCCCAAACCTGTAATTGTGCGAATGTCCGATTTTAAGAGTAATGAATATCGCA
ACCTTGCAGGGGGTTCCCAATTTGAACCAGATGAAGAAAACCCGATGCTGGGTTGGCGGGGGGCTGCACGTTATTATGAT
CCAGGGTACAGAGAAGGTTTTGCTTTAGAATGCCATGCTATCAAGCGGGTGCGGGATGAGATGGGGTTAACTAACGTTAT
TCCCATGATTCCTTTCTGTCGCACACCAGAGGAGGGACGCTTGGTTTTAGCAGAGATGGCGAAACATGATTTAAAACAAG
GTGTGAACGACTTGCAGGTTTATGTAATGTGTGAGTTACCAAGTAACGTCATCTTGGCCGAACAGTTTGCAGAGGTGTTC
GACGGTTTCTCCATCGGTTCCAACGACTTGACTCAGCTGACACTAGGATTAGATAGAGATTCAGCTTTAGTCGCTCGACT
ATTTGACGAACGTAGCCCAGCTGTGAAACAAATGGTGAAAATGGCGATCGCCTCTGCAAAAAAACAACGCCGCAAAATCG
GCATCTGTGGGCAGGCACCAAGCGATTACCCGGAATTTGCCCAGTTTTTGGTAGAAGAGGGAATTGATTCCATTAGTCTC
AATCCCGACTCTGTATTAAAAACGATGCTGGAAATAGCTAAGGTGGAACAGCAAAGCTGA

Upstream 100 bases:

>100_bases
TTCTGTCCACCGTAGGCGAGCGATCGCCAAATAACGAAAATAAATGCAACAAAAAACTAATTCTCCATAACCAGAGCATT
AATTAAGGGAGGTAATACTG

Downstream 100 bases:

>100_bases
GGCAAGAGGTAAATCAATTCAAAATTCAAAATACCCTTCGGGAACGCCAAGGGCGAACAAAATTCAAAATTAGAGAATTG
CTTACTCAGCAAAATTTACA

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 819; Mature: 819

Protein sequence:

>819_residues
MVTVSQNTLAKCSQEESLVLWLDKVGIKDIALVGGKNASLGEMIQQLTPKGVNVPTGFATTAYAYRYFIQSAGLEAKLRE
LFADLDVEDVRNLQERGLKARSLLMHTPFPVELQQAIASAYESLCKQYNPDTDVAVRSSATAEDLPDASFAGQQETYLNV
VGAEEVLAACHKCFASLFTDRAISYRHTKGFDHFSVALAVGVQKMVRSDLATSGVMFSIDTETGFKDAALITAAYGLGEN
VVQGAVNPDEYCVFKPTLKAGFKPIIDKKLGSKELRMVYDEGSQSTKNEAVSIVEQNQFALNDADILQLAHWACLIEDHY
SQAHGSYTPMDIEWAKDGITNQLFVVQARPETVQSQKNGNVLRSYRLGLGTGEKTQNISLLPLVTGRAIGEAISQGKARV
ILDAKQIEEFQAGEVLVTERTDPDWEPIMKRASAIITNSGGRTCHAAIIARELGVPAIVGCGNATQVLTTGQEVTVSCAE
GEEGKVYPGLLPFEVKEVPLENLPRTHTQILMNVGNPQEAFSLSAIPNDGVGLARTEFIIANQIQVHPLALIHYDKLADA
EQKAKVAAITATYEDKPQYFVDKLAQGVGRIAAAFYPKPVIVRMSDFKSNEYRNLAGGSQFEPDEENPMLGWRGAARYYD
PGYREGFALECHAIKRVRDEMGLTNVIPMIPFCRTPEEGRLVLAEMAKHDLKQGVNDLQVYVMCELPSNVILAEQFAEVF
DGFSIGSNDLTQLTLGLDRDSALVARLFDERSPAVKQMVKMAIASAKKQRRKIGICGQAPSDYPEFAQFLVEEGIDSISL
NPDSVLKTMLEIAKVEQQS

Sequences:

>Translated_819_residues
MVTVSQNTLAKCSQEESLVLWLDKVGIKDIALVGGKNASLGEMIQQLTPKGVNVPTGFATTAYAYRYFIQSAGLEAKLRE
LFADLDVEDVRNLQERGLKARSLLMHTPFPVELQQAIASAYESLCKQYNPDTDVAVRSSATAEDLPDASFAGQQETYLNV
VGAEEVLAACHKCFASLFTDRAISYRHTKGFDHFSVALAVGVQKMVRSDLATSGVMFSIDTETGFKDAALITAAYGLGEN
VVQGAVNPDEYCVFKPTLKAGFKPIIDKKLGSKELRMVYDEGSQSTKNEAVSIVEQNQFALNDADILQLAHWACLIEDHY
SQAHGSYTPMDIEWAKDGITNQLFVVQARPETVQSQKNGNVLRSYRLGLGTGEKTQNISLLPLVTGRAIGEAISQGKARV
ILDAKQIEEFQAGEVLVTERTDPDWEPIMKRASAIITNSGGRTCHAAIIARELGVPAIVGCGNATQVLTTGQEVTVSCAE
GEEGKVYPGLLPFEVKEVPLENLPRTHTQILMNVGNPQEAFSLSAIPNDGVGLARTEFIIANQIQVHPLALIHYDKLADA
EQKAKVAAITATYEDKPQYFVDKLAQGVGRIAAAFYPKPVIVRMSDFKSNEYRNLAGGSQFEPDEENPMLGWRGAARYYD
PGYREGFALECHAIKRVRDEMGLTNVIPMIPFCRTPEEGRLVLAEMAKHDLKQGVNDLQVYVMCELPSNVILAEQFAEVF
DGFSIGSNDLTQLTLGLDRDSALVARLFDERSPAVKQMVKMAIASAKKQRRKIGICGQAPSDYPEFAQFLVEEGIDSISL
NPDSVLKTMLEIAKVEQQS
>Mature_819_residues
MVTVSQNTLAKCSQEESLVLWLDKVGIKDIALVGGKNASLGEMIQQLTPKGVNVPTGFATTAYAYRYFIQSAGLEAKLRE
LFADLDVEDVRNLQERGLKARSLLMHTPFPVELQQAIASAYESLCKQYNPDTDVAVRSSATAEDLPDASFAGQQETYLNV
VGAEEVLAACHKCFASLFTDRAISYRHTKGFDHFSVALAVGVQKMVRSDLATSGVMFSIDTETGFKDAALITAAYGLGEN
VVQGAVNPDEYCVFKPTLKAGFKPIIDKKLGSKELRMVYDEGSQSTKNEAVSIVEQNQFALNDADILQLAHWACLIEDHY
SQAHGSYTPMDIEWAKDGITNQLFVVQARPETVQSQKNGNVLRSYRLGLGTGEKTQNISLLPLVTGRAIGEAISQGKARV
ILDAKQIEEFQAGEVLVTERTDPDWEPIMKRASAIITNSGGRTCHAAIIARELGVPAIVGCGNATQVLTTGQEVTVSCAE
GEEGKVYPGLLPFEVKEVPLENLPRTHTQILMNVGNPQEAFSLSAIPNDGVGLARTEFIIANQIQVHPLALIHYDKLADA
EQKAKVAAITATYEDKPQYFVDKLAQGVGRIAAAFYPKPVIVRMSDFKSNEYRNLAGGSQFEPDEENPMLGWRGAARYYD
PGYREGFALECHAIKRVRDEMGLTNVIPMIPFCRTPEEGRLVLAEMAKHDLKQGVNDLQVYVMCELPSNVILAEQFAEVF
DGFSIGSNDLTQLTLGLDRDSALVARLFDERSPAVKQMVKMAIASAKKQRRKIGICGQAPSDYPEFAQFLVEEGIDSISL
NPDSVLKTMLEIAKVEQQS

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=803, Percent_Identity=54.0473225404732, Blast_Score=872, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=405, Percent_Identity=26.9135802469136, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI48994992, Length=371, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1789193, Length=413, Percent_Identity=25.181598062954, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788726, Length=382, Percent_Identity=24.869109947644, Blast_Score=86, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17564524, Length=243, Percent_Identity=29.2181069958848, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 89683; Mature: 89683

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVSQNTLAKCSQEESLVLWLDKVGIKDIALVGGKNASLGEMIQQLTPKGVNVPTGFAT
CEEECCHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHH
TAYAYRYFIQSAGLEAKLRELFADLDVEDVRNLQERGLKARSLLMHTPFPVELQQAIASA
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHH
YESLCKQYNPDTDVAVRSSATAEDLPDASFAGQQETYLNVVGAEEVLAACHKCFASLFTD
HHHHHHHCCCCCCEEEECCCCHHCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHH
RAISYRHTKGFDHFSVALAVGVQKMVRSDLATSGVMFSIDTETGFKDAALITAAYGLGEN
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCH
VVQGAVNPDEYCVFKPTLKAGFKPIIDKKLGSKELRMVYDEGSQSTKNEAVSIVEQNQFA
HHHCCCCCCCEEEECCCHHHCCHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHEECCCEE
LNDADILQLAHWACLIEDHYSQAHGSYTPMDIEWAKDGITNQLFVVQARPETVQSQKNGN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEECCHHHHHCCCCC
VLRSYRLGLGTGEKTQNISLLPLVTGRAIGEAISQGKARVILDAKQIEEFQAGEVLVTER
EEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCEEEECC
TDPDWEPIMKRASAIITNSGGRTCHAAIIARELGVPAIVGCGNATQVLTTGQEVTVSCAE
CCCCHHHHHHHHHEEEECCCCCEEHHHHHHHHCCCCEEEECCCCCEEEECCCEEEEEECC
GEEGKVYPGLLPFEVKEVPLENLPRTHTQILMNVGNPQEAFSLSAIPNDGVGLARTEFII
CCCCCCCCCCCCCHHHHCCHHHCCCHHHHHEEECCCCHHHEEEECCCCCCCCCEEEEEEE
ANQIQVHPLALIHYDKLADAEQKAKVAAITATYEDKPQYFVDKLAQGVGRIAAAFYPKPV
ECCEEECEEEEEEEHHHCCHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCE
IVRMSDFKSNEYRNLAGGSQFEPDEENPMLGWRGAARYYDPGYREGFALECHAIKRVRDE
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHH
MGLTNVIPMIPFCRTPEEGRLVLAEMAKHDLKQGVNDLQVYVMCELPSNVILAEQFAEVF
CCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHH
DGFSIGSNDLTQLTLGLDRDSALVARLFDERSPAVKQMVKMAIASAKKQRRKIGICGQAP
CCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SDYPEFAQFLVEEGIDSISLNPDSVLKTMLEIAKVEQQS
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTVSQNTLAKCSQEESLVLWLDKVGIKDIALVGGKNASLGEMIQQLTPKGVNVPTGFAT
CEEECCHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCCCHHH
TAYAYRYFIQSAGLEAKLRELFADLDVEDVRNLQERGLKARSLLMHTPFPVELQQAIASA
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHH
YESLCKQYNPDTDVAVRSSATAEDLPDASFAGQQETYLNVVGAEEVLAACHKCFASLFTD
HHHHHHHCCCCCCEEEECCCCHHCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHH
RAISYRHTKGFDHFSVALAVGVQKMVRSDLATSGVMFSIDTETGFKDAALITAAYGLGEN
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCCCCH
VVQGAVNPDEYCVFKPTLKAGFKPIIDKKLGSKELRMVYDEGSQSTKNEAVSIVEQNQFA
HHHCCCCCCCEEEECCCHHHCCHHHHHHHCCCCHHEEEECCCCCCCHHHHHHHEECCCEE
LNDADILQLAHWACLIEDHYSQAHGSYTPMDIEWAKDGITNQLFVVQARPETVQSQKNGN
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEEECCHHHHHCCCCC
VLRSYRLGLGTGEKTQNISLLPLVTGRAIGEAISQGKARVILDAKQIEEFQAGEVLVTER
EEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEEHHHHHHHCCCCEEEECC
TDPDWEPIMKRASAIITNSGGRTCHAAIIARELGVPAIVGCGNATQVLTTGQEVTVSCAE
CCCCHHHHHHHHHEEEECCCCCEEHHHHHHHHCCCCEEEECCCCCEEEECCCEEEEEECC
GEEGKVYPGLLPFEVKEVPLENLPRTHTQILMNVGNPQEAFSLSAIPNDGVGLARTEFII
CCCCCCCCCCCCCHHHHCCHHHCCCHHHHHEEECCCCHHHEEEECCCCCCCCCEEEEEEE
ANQIQVHPLALIHYDKLADAEQKAKVAAITATYEDKPQYFVDKLAQGVGRIAAAFYPKPV
ECCEEECEEEEEEEHHHCCHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCE
IVRMSDFKSNEYRNLAGGSQFEPDEENPMLGWRGAARYYDPGYREGFALECHAIKRVRDE
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHH
MGLTNVIPMIPFCRTPEEGRLVLAEMAKHDLKQGVNDLQVYVMCELPSNVILAEQFAEVF
CCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHH
DGFSIGSNDLTQLTLGLDRDSALVARLFDERSPAVKQMVKMAIASAKKQRRKIGICGQAP
CCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SDYPEFAQFLVEEGIDSISLNPDSVLKTMLEIAKVEQQS
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]