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The map label for this gene is arcB [C]

Identifier: 75909975

GI number: 75909975

Start: 4693523

End: 4695667

Strand: Direct

Name: arcB [C]

Synonym: Ava_3771

Alternate gene names: 75909975

Gene position: 4693523-4695667 (Clockwise)

Preceding gene: 75909974

Following gene: 75909976

Centisome position: 73.73

GC content: 42.24

Gene sequence:

>2145_bases
ATGAGTGTATTAAATATGAATCATGATGAGTATAATCAAGAGTCATTAAAAAACGTAAACAAACAAGCCCAAGAAGCACT
ACAACAGCAAATTGAACGGCAGCGATTGGTAATGGCGATCGCAGTACGTATTCGTGAGAGTTTACGTCTCAATGAAGTTT
TAAACACCACTGTGGCGGAAGTACGCCAGTTCCTTCAGGCAGACCGAGTGTTTATTTACCGCTTTGCACCAAATTACAGT
GGGTGTGTAGTGGTGGAATCTGTTGGTGATAATTGGCGTGCTGTATTGAATGCCCAAGTGGAAGATACTTACTTCATGGA
AACTCACGGAGAAAAATATAGACAAGGAGGCTTACAGGCGATCGCAGACATTTATGCAGAAGATATCAGCGAATGTCACC
GGGATTTACTAATTCAATTCCAGGTCAAAGCAAACTTGGTAGTCCCTATTTTGCAGGGGGAAAAGCTATGGGGGTTATTA
GTTACCAACCAGTGTGGAACATCAAGACATTGGCAGTCTTGGGAAATCGATTTACTCCAACAATTAGCAACCCAAGTAGG
TATCGCCATTCAGCAATCGGAACTATACGAGCAGGTACGTGCTGAACTCAAAGAGCGCAAGCAAGCAGAACAGAAAGTCC
GTGAACAAGCAGCCCTATTGGATATTGCGACTGATGCAATTTTAGTCCGAGATTTTCATAGCCAAATCTTGTTTTGGAAT
AAGGCGGCGGAGCGTCTATATGGTTGGCAAGCTCATGAGGCTATAGGAAAAAATTCTGAGGAACTTTTATTCAAAGAAAG
CTCCTCTCAACTGGAATTAGTTCGCAACCACGTCTTGGAGCATGGTTCATGGCAAGGTGAATTAAATAAAATCACAAAAT
CCGGTAAAGAAATCATTGTAGAAAGCCGTTGGAATCTGATGTTTGATGAATCAGGCCAACCTAAATCTATTTTGACTGTG
GACACAGACATCACCGAAAAAAAACAACTGCAAGCTCAATTTCTCCGCGCTCAACGCATGGAAAGTCTGGGTACACTAGC
TAGCGGTATTGCCCATGACCTCAACAACATCTTGACACCTATCATGGCTTCTATTCAGTTGTTGGCGCTCAAGTCTTCCA
GTAACGATGCTCGTAACCATCAATTGCTGAAGATTCTGGAACATAACTCTAAACGTGCAGCCGATTTAGTCAAACAGATT
TTAACATTTGCACGGGGTTCAGAAACCAGGGGTGTGACTTTGCAAATCGAACCTTTACTGTTAGAAATTGAACAGATTCT
CAACAGCACATTTCCCAAATCTATCAAAATTACTAAGCATCTACCGCCTGAAAACCTATGGACTATTCAGGCAGATCCTA
CACAAATACATCAAGTGTTGATGAATCTGTGCGTTAATGCTCGTGATGCGATGCCGGGAAATGGTACCCTCTCCATATTT
GCAGAAAATCTCCTGGTAGATAAGAATTTTGCCAAGATGAATTTAGACGCTGAGGTAGGCCCCTATGTAGTCATCACCAT
TGCGGATACTGGATTTGGCATTCCACCATTAATTTTAGAGCGAATTTTTGAACCCTTTTTCACTACCAAAGAATCAGGTA
AAGGTACTGGGCTTGGTCTTTCCACTGTGATTGGTATTGTCAAGAACCACGGCGGTTTTGTGAATGTGAATAGCGAAATC
GGCAAAGGTAGCCAGTTTCAGGTGTTTTTGCCGGCTGTCGAGGATAGAGCAAAACAGCAAGTAGAAGACCTTGATTTGCC
TGCTGGTCAAGGAGAATTGATTCTGATTGTAGATGATGAAGCCGCTATTGTAGAAATTACCAAGACTTCTTTAGAAGACT
ACAACTACAAAACTCTAACTGCCAAAAATGGGATTGAGGCGATCGCTCTCTATGCCCAACATCAAGATAAAATCAGCATG
GTGCTGATGGATATAATGATGCCCTCAATGGATGGGTTAACTGCCATTCGGATTCTGCAAGAAATGAATCCACAACTCAA
AATTATTGCTATTAGTGGCATCACTGGCAATAACCAACTTGCGGAAGCTGCTAACGCTGGTGTCAATGCCTTTTTGCGAA
AGCCTTACAACATCTATGATTTAGTCCACGCTATTCACAACATCTTCCATCAGGTGACACAATAG

Upstream 100 bases:

>100_bases
AAATCTTGAAGAAAACTCATAAATATTTCCAAGAAATTGACGGGAAATCTATATAAAAGCATTAGAAAAATCCCCAAGAT
ATTCATAACTCATTGATGAG

Downstream 100 bases:

>100_bases
CCAAACCATCAATTGCCATAGTTATTGGTTTGTACCTTATCCTAAGGATACCAAACACTGAATGCTTGCGTTGCTTTTAG
AGAATGCTTGGCTGCAAAGC

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MSVLNMNHDEYNQESLKNVNKQAQEALQQQIERQRLVMAIAVRIRESLRLNEVLNTTVAEVRQFLQADRVFIYRFAPNYS
GCVVVESVGDNWRAVLNAQVEDTYFMETHGEKYRQGGLQAIADIYAEDISECHRDLLIQFQVKANLVVPILQGEKLWGLL
VTNQCGTSRHWQSWEIDLLQQLATQVGIAIQQSELYEQVRAELKERKQAEQKVREQAALLDIATDAILVRDFHSQILFWN
KAAERLYGWQAHEAIGKNSEELLFKESSSQLELVRNHVLEHGSWQGELNKITKSGKEIIVESRWNLMFDESGQPKSILTV
DTDITEKKQLQAQFLRAQRMESLGTLASGIAHDLNNILTPIMASIQLLALKSSSNDARNHQLLKILEHNSKRAADLVKQI
LTFARGSETRGVTLQIEPLLLEIEQILNSTFPKSIKITKHLPPENLWTIQADPTQIHQVLMNLCVNARDAMPGNGTLSIF
AENLLVDKNFAKMNLDAEVGPYVVITIADTGFGIPPLILERIFEPFFTTKESGKGTGLGLSTVIGIVKNHGGFVNVNSEI
GKGSQFQVFLPAVEDRAKQQVEDLDLPAGQGELILIVDDEAAIVEITKTSLEDYNYKTLTAKNGIEAIALYAQHQDKISM
VLMDIMMPSMDGLTAIRILQEMNPQLKIIAISGITGNNQLAEAANAGVNAFLRKPYNIYDLVHAIHNIFHQVTQ

Sequences:

>Translated_714_residues
MSVLNMNHDEYNQESLKNVNKQAQEALQQQIERQRLVMAIAVRIRESLRLNEVLNTTVAEVRQFLQADRVFIYRFAPNYS
GCVVVESVGDNWRAVLNAQVEDTYFMETHGEKYRQGGLQAIADIYAEDISECHRDLLIQFQVKANLVVPILQGEKLWGLL
VTNQCGTSRHWQSWEIDLLQQLATQVGIAIQQSELYEQVRAELKERKQAEQKVREQAALLDIATDAILVRDFHSQILFWN
KAAERLYGWQAHEAIGKNSEELLFKESSSQLELVRNHVLEHGSWQGELNKITKSGKEIIVESRWNLMFDESGQPKSILTV
DTDITEKKQLQAQFLRAQRMESLGTLASGIAHDLNNILTPIMASIQLLALKSSSNDARNHQLLKILEHNSKRAADLVKQI
LTFARGSETRGVTLQIEPLLLEIEQILNSTFPKSIKITKHLPPENLWTIQADPTQIHQVLMNLCVNARDAMPGNGTLSIF
AENLLVDKNFAKMNLDAEVGPYVVITIADTGFGIPPLILERIFEPFFTTKESGKGTGLGLSTVIGIVKNHGGFVNVNSEI
GKGSQFQVFLPAVEDRAKQQVEDLDLPAGQGELILIVDDEAAIVEITKTSLEDYNYKTLTAKNGIEAIALYAQHQDKISM
VLMDIMMPSMDGLTAIRILQEMNPQLKIIAISGITGNNQLAEAANAGVNAFLRKPYNIYDLVHAIHNIFHQVTQ
>Mature_713_residues
SVLNMNHDEYNQESLKNVNKQAQEALQQQIERQRLVMAIAVRIRESLRLNEVLNTTVAEVRQFLQADRVFIYRFAPNYSG
CVVVESVGDNWRAVLNAQVEDTYFMETHGEKYRQGGLQAIADIYAEDISECHRDLLIQFQVKANLVVPILQGEKLWGLLV
TNQCGTSRHWQSWEIDLLQQLATQVGIAIQQSELYEQVRAELKERKQAEQKVREQAALLDIATDAILVRDFHSQILFWNK
AAERLYGWQAHEAIGKNSEELLFKESSSQLELVRNHVLEHGSWQGELNKITKSGKEIIVESRWNLMFDESGQPKSILTVD
TDITEKKQLQAQFLRAQRMESLGTLASGIAHDLNNILTPIMASIQLLALKSSSNDARNHQLLKILEHNSKRAADLVKQIL
TFARGSETRGVTLQIEPLLLEIEQILNSTFPKSIKITKHLPPENLWTIQADPTQIHQVLMNLCVNARDAMPGNGTLSIFA
ENLLVDKNFAKMNLDAEVGPYVVITIADTGFGIPPLILERIFEPFFTTKESGKGTGLGLSTVIGIVKNHGGFVNVNSEIG
KGSQFQVFLPAVEDRAKQQVEDLDLPAGQGELILIVDDEAAIVEITKTSLEDYNYKTLTAKNGIEAIALYAQHQDKISMV
LMDIMMPSMDGLTAIRILQEMNPQLKIIAISGITGNNQLAEAANAGVNAFLRKPYNIYDLVHAIHNIFHQVTQ

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=557, Percent_Identity=23.8779174147217, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788549, Length=371, Percent_Identity=28.3018867924528, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87081816, Length=386, Percent_Identity=23.3160621761658, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1790300, Length=358, Percent_Identity=25.1396648044693, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=411, Percent_Identity=23.3576642335766, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=289, Percent_Identity=25.2595155709343, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=241, Percent_Identity=26.1410788381743, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786600, Length=413, Percent_Identity=21.3075060532688, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80180; Mature: 80049

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLNMNHDEYNQESLKNVNKQAQEALQQQIERQRLVMAIAVRIRESLRLNEVLNTTVAE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRQFLQADRVFIYRFAPNYSGCVVVESVGDNWRAVLNAQVEDTYFMETHGEKYRQGGLQA
HHHHHHHCCEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHH
IADIYAEDISECHRDLLIQFQVKANLVVPILQGEKLWGLLVTNQCGTSRHWQSWEIDLLQ
HHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHH
QLATQVGIAIQQSELYEQVRAELKERKQAEQKVREQAALLDIATDAILVRDFHSQILFWN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHH
KAAERLYGWQAHEAIGKNSEELLFKESSSQLELVRNHVLEHGSWQGELNKITKSGKEIIV
HHHHHHHCCHHHHHHCCCCHHEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEE
ESRWNLMFDESGQPKSILTVDTDITEKKQLQAQFLRAQRMESLGTLASGIAHDLNNILTP
ECCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMASIQLLALKSSSNDARNHQLLKILEHNSKRAADLVKQILTFARGSETRGVTLQIEPLL
HHHHHEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
LEIEQILNSTFPKSIKITKHLPPENLWTIQADPTQIHQVLMNLCVNARDAMPGNGTLSIF
HHHHHHHHCCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEEE
AENLLVDKNFAKMNLDAEVGPYVVITIADTGFGIPPLILERIFEPFFTTKESGKGTGLGL
EEHHEEECCHHEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
STVIGIVKNHGGFVNVNSEIGKGSQFQVFLPAVEDRAKQQVEDLDLPAGQGELILIVDDE
HHHHHHHHCCCCEEEECCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCEEEEECCC
AAIVEITKTSLEDYNYKTLTAKNGIEAIALYAQHQDKISMVLMDIMMPSMDGLTAIRILQ
CEEEEEEHHHHCCCCEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHCCCCCCHHHHHHHH
EMNPQLKIIAISGITGNNQLAEAANAGVNAFLRKPYNIYDLVHAIHNIFHQVTQ
HCCCCEEEEEEECCCCCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVLNMNHDEYNQESLKNVNKQAQEALQQQIERQRLVMAIAVRIRESLRLNEVLNTTVAE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRQFLQADRVFIYRFAPNYSGCVVVESVGDNWRAVLNAQVEDTYFMETHGEKYRQGGLQA
HHHHHHHCCEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHH
IADIYAEDISECHRDLLIQFQVKANLVVPILQGEKLWGLLVTNQCGTSRHWQSWEIDLLQ
HHHHHHHHHHHHHHHHEEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCHHHHH
QLATQVGIAIQQSELYEQVRAELKERKQAEQKVREQAALLDIATDAILVRDFHSQILFWN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHH
KAAERLYGWQAHEAIGKNSEELLFKESSSQLELVRNHVLEHGSWQGELNKITKSGKEIIV
HHHHHHHCCHHHHHHCCCCHHEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEE
ESRWNLMFDESGQPKSILTVDTDITEKKQLQAQFLRAQRMESLGTLASGIAHDLNNILTP
ECCCCEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMASIQLLALKSSSNDARNHQLLKILEHNSKRAADLVKQILTFARGSETRGVTLQIEPLL
HHHHHEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
LEIEQILNSTFPKSIKITKHLPPENLWTIQADPTQIHQVLMNLCVNARDAMPGNGTLSIF
HHHHHHHHCCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEEE
AENLLVDKNFAKMNLDAEVGPYVVITIADTGFGIPPLILERIFEPFFTTKESGKGTGLGL
EEHHEEECCHHEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCH
STVIGIVKNHGGFVNVNSEIGKGSQFQVFLPAVEDRAKQQVEDLDLPAGQGELILIVDDE
HHHHHHHHCCCCEEEECCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCCCEEEEECCC
AAIVEITKTSLEDYNYKTLTAKNGIEAIALYAQHQDKISMVLMDIMMPSMDGLTAIRILQ
CEEEEEEHHHHCCCCEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHCCCCCCHHHHHHHH
EMNPQLKIIAISGITGNNQLAEAANAGVNAFLRKPYNIYDLVHAIHNIFHQVTQ
HCCCCEEEEEEECCCCCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA