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The map label for this gene is glmM

Identifier: 75909973

GI number: 75909973

Start: 4690375

End: 4691847

Strand: Direct

Name: glmM

Synonym: Ava_3769

Alternate gene names: 75909973

Gene position: 4690375-4691847 (Clockwise)

Preceding gene: 161567473

Following gene: 75909974

Centisome position: 73.68

GC content: 46.98

Gene sequence:

>1473_bases
ATGGTTTCATCTATAACTCGGATTCAGAACTACGTAATAGATGGTGCAGCTACATCTGATGGATTAGCAACAGTCCTTGA
GAGCAACTTTGCACCTAGTTTAATATCTCTACCAGCAACGCCTCTTTTTGGTACAGATGGTATTCGTGGCAAGGTGGGGG
AATTACTTAGTGCGCCGTTAGCGTTGCAAATTGGTTTTTGGGCAGGCGTAGTTTTACGTAGTCACGCTGGTCAATTAAGA
CCAGTAATCTTAGGGCAGGATTCCCGTAACTCTAGCGATATGTTGGCGATGGCTTTAAGTGCAGGGTTAACCGCCGCCGG
GCTAGAAGTTTGGTATTTAGGGTTATGTCCTACTCCTTGCGTGGCTTATTTAACTAGTGTGAGTGAAGCCATAGGTGGTG
TGATGATTTCTGCTAGTCACAACCCTCCCGAAGATAACGGGATTAAAATTTTTGGTGCTAATGGTGGGAAGTTATCCCAG
GCTTTGCAGGCAGAAATTGAAAAAGGTTTGCGGGGAAATCTGCCAATTACCAGTAATGTCAGTAATTGTGGACGGCATTA
CTCACGCCGGGAATTGGTGAAAGATTACGGCGAAGCTTTAAAACGACCCTGGCAAAATAAAGTGAATCTTCAGGGAATGA
AGGTTGTACTGGATTTAGCTTGGGGTGCAGCCGTTGGGTTAGCACCGTCGGTATTTGCAGAGATGGGGGCAGAAGTTATT
TCCCTGCATAATGCCGCAGATGGCGATCGCATCAACGTTAACTGCGGTTCCACCCACCTAGAAATGTTGCAAGCGGCTGT
TCAAGAACATAACGCCGATTTAGGTTTTGCCTTTGATGGCGATGCCGATCGCGTTTTGGCTGTAGATCCTACCGGCCGTC
CTGTAAATGGGGACTATATCTTGTACCTGTGGGGATTGCACCTCAAACAACAAAACCAACTCCCAGACAACTTGATTGTT
TCCACCGTCATGGCAAACCTGGGCTTTGAGAAAGCTTGGCAGCAACAGGGTGGTAAATTAATTCGCACCGCCGTTGGTGA
TCAATATGTGCAAGCAGAAATGATCAAAACTGGGGCAATGTTGGGGGGTGAACAATCAGGACACATTCTTTGTAGTCATT
ATGGGATGACTGGGGATGGCTTGTTAACAGCCTTACACTTGGCAAGTTTGGTCAAACAATCTGGTGTTTCCTTAGCCGAA
TTGATAGACCAAAGCTTCCAGACCTATCCTCAATTATTGCGGAACGTGCGAGTTGTAGACCGCGATCGCCGCCTGAATTG
GCAAAACTGCACACCAGTACAACAGGCGATCGCTCTTGCCGAGAAAGCAATGGGTGATACTGGTAGAATTTTAGTTAGGG
CATCCGGTACAGAACCCGTCATCAGAGTCATGGTAGAAGCCGCCAACGCCGAACTAGCTAACTATTGGACAAATGAACTA
GTAGCCCAGGTACAACAACACCTAGCGCCTTAA

Upstream 100 bases:

>100_bases
ACTGAGAACTGGGTTGTTTACTCAGCACTCAATACTTAAAATCTGTCGAACTGGCGTTAAAGTAATAATTCTTAGTGTGA
TGTGAGGGGTGTTTAAAATT

Downstream 100 bases:

>100_bases
CTGAGTTCGACACTTCCCATCCTTGAGGCAGAGGGGAAGGGAGCAGGGAGCAGGGGGCAGGGGGAGCAGGGGAGGCAGGG
GGAGAAGTCCCCAATCCCCA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MVSSITRIQNYVIDGAATSDGLATVLESNFAPSLISLPATPLFGTDGIRGKVGELLSAPLALQIGFWAGVVLRSHAGQLR
PVILGQDSRNSSDMLAMALSAGLTAAGLEVWYLGLCPTPCVAYLTSVSEAIGGVMISASHNPPEDNGIKIFGANGGKLSQ
ALQAEIEKGLRGNLPITSNVSNCGRHYSRRELVKDYGEALKRPWQNKVNLQGMKVVLDLAWGAAVGLAPSVFAEMGAEVI
SLHNAADGDRINVNCGSTHLEMLQAAVQEHNADLGFAFDGDADRVLAVDPTGRPVNGDYILYLWGLHLKQQNQLPDNLIV
STVMANLGFEKAWQQQGGKLIRTAVGDQYVQAEMIKTGAMLGGEQSGHILCSHYGMTGDGLLTALHLASLVKQSGVSLAE
LIDQSFQTYPQLLRNVRVVDRDRRLNWQNCTPVQQAIALAEKAMGDTGRILVRASGTEPVIRVMVEAANAELANYWTNEL
VAQVQQHLAP

Sequences:

>Translated_490_residues
MVSSITRIQNYVIDGAATSDGLATVLESNFAPSLISLPATPLFGTDGIRGKVGELLSAPLALQIGFWAGVVLRSHAGQLR
PVILGQDSRNSSDMLAMALSAGLTAAGLEVWYLGLCPTPCVAYLTSVSEAIGGVMISASHNPPEDNGIKIFGANGGKLSQ
ALQAEIEKGLRGNLPITSNVSNCGRHYSRRELVKDYGEALKRPWQNKVNLQGMKVVLDLAWGAAVGLAPSVFAEMGAEVI
SLHNAADGDRINVNCGSTHLEMLQAAVQEHNADLGFAFDGDADRVLAVDPTGRPVNGDYILYLWGLHLKQQNQLPDNLIV
STVMANLGFEKAWQQQGGKLIRTAVGDQYVQAEMIKTGAMLGGEQSGHILCSHYGMTGDGLLTALHLASLVKQSGVSLAE
LIDQSFQTYPQLLRNVRVVDRDRRLNWQNCTPVQQAIALAEKAMGDTGRILVRASGTEPVIRVMVEAANAELANYWTNEL
VAQVQQHLAP
>Mature_490_residues
MVSSITRIQNYVIDGAATSDGLATVLESNFAPSLISLPATPLFGTDGIRGKVGELLSAPLALQIGFWAGVVLRSHAGQLR
PVILGQDSRNSSDMLAMALSAGLTAAGLEVWYLGLCPTPCVAYLTSVSEAIGGVMISASHNPPEDNGIKIFGANGGKLSQ
ALQAEIEKGLRGNLPITSNVSNCGRHYSRRELVKDYGEALKRPWQNKVNLQGMKVVLDLAWGAAVGLAPSVFAEMGAEVI
SLHNAADGDRINVNCGSTHLEMLQAAVQEHNADLGFAFDGDADRVLAVDPTGRPVNGDYILYLWGLHLKQQNQLPDNLIV
STVMANLGFEKAWQQQGGKLIRTAVGDQYVQAEMIKTGAMLGGEQSGHILCSHYGMTGDGLLTALHLASLVKQSGVSLAE
LIDQSFQTYPQLLRNVRVVDRDRRLNWQNCTPVQQAIALAEKAMGDTGRILVRASGTEPVIRVMVEAANAELANYWTNEL
VAQVQQHLAP

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Homo sapiens, GI63055049, Length=551, Percent_Identity=22.1415607985481, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI31377548, Length=420, Percent_Identity=22.6190476190476, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789566, Length=445, Percent_Identity=39.3258426966292, Blast_Score=264, Evalue=8e-72,
Organism=Escherichia coli, GI1788361, Length=443, Percent_Identity=28.2167042889391, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786904, Length=354, Percent_Identity=24.2937853107345, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_ANAVT (Q3M6L2)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_324269.1
- HSSP:   Q9P4V2
- ProteinModelPortal:   Q3M6L2
- SMR:   Q3M6L2
- STRING:   Q3M6L2
- GeneID:   3678973
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_3769
- NMPDR:   fig|240292.3.peg.3887
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q3M6L2
- ProtClustDB:   PRK14317
- BioCyc:   AVAR240292:AVA_3769-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 52407; Mature: 52407

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 139-139

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSITRIQNYVIDGAATSDGLATVLESNFAPSLISLPATPLFGTDGIRGKVGELLSAPL
CCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCH
ALQIGFWAGVVLRSHAGQLRPVILGQDSRNSSDMLAMALSAGLTAAGLEVWYLGLCPTPC
HEEHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHCCEEEEEECCCHHH
VAYLTSVSEAIGGVMISASHNPPEDNGIKIFGANGGKLSQALQAEIEKGLRGNLPITSNV
HHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCH
SNCGRHYSRRELVKDYGEALKRPWQNKVNLQGMKVVLDLAWGAAVGLAPSVFAEMGAEVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEHHHHHHHCCCHHHHHHHCHHHH
SLHNAADGDRINVNCGSTHLEMLQAAVQEHNADLGFAFDGDADRVLAVDPTGRPVNGDYI
HHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCEE
LYLWGLHLKQQNQLPDNLIVSTVMANLGFEKAWQQQGGKLIRTAVGDQYVQAEMIKTGAM
EEEEEEHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEHHHHCCHHHHHHHHHHHHH
LGGEQSGHILCSHYGMTGDGLLTALHLASLVKQSGVSLAELIDQSFQTYPQLLRNVRVVD
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHC
RDRRLNWQNCTPVQQAIALAEKAMGDTGRILVRASGTEPVIRVMVEAANAELANYWTNEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHH
VAQVQQHLAP
HHHHHHHCCC
>Mature Secondary Structure
MVSSITRIQNYVIDGAATSDGLATVLESNFAPSLISLPATPLFGTDGIRGKVGELLSAPL
CCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCH
ALQIGFWAGVVLRSHAGQLRPVILGQDSRNSSDMLAMALSAGLTAAGLEVWYLGLCPTPC
HEEHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHCCCCHHCCEEEEEECCCHHH
VAYLTSVSEAIGGVMISASHNPPEDNGIKIFGANGGKLSQALQAEIEKGLRGNLPITSNV
HHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCH
SNCGRHYSRRELVKDYGEALKRPWQNKVNLQGMKVVLDLAWGAAVGLAPSVFAEMGAEVI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEHHHHHHHCCCHHHHHHHCHHHH
SLHNAADGDRINVNCGSTHLEMLQAAVQEHNADLGFAFDGDADRVLAVDPTGRPVNGDYI
HHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCEE
LYLWGLHLKQQNQLPDNLIVSTVMANLGFEKAWQQQGGKLIRTAVGDQYVQAEMIKTGAM
EEEEEEHHHHCCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEHHHHCCHHHHHHHHHHHHH
LGGEQSGHILCSHYGMTGDGLLTALHLASLVKQSGVSLAELIDQSFQTYPQLLRNVRVVD
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHHC
RDRRLNWQNCTPVQQAIALAEKAMGDTGRILVRASGTEPVIRVMVEAANAELANYWTNEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHH
VAQVQQHLAP
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA