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The map label for this gene is prmA

Identifier: 75909964

GI number: 75909964

Start: 4682250

End: 4683170

Strand: Direct

Name: prmA

Synonym: Ava_3760

Alternate gene names: 75909964

Gene position: 4682250-4683170 (Clockwise)

Preceding gene: 75909963

Following gene: 75909965

Centisome position: 73.55

GC content: 44.19

Gene sequence:

>921_bases
ATGGCAAACACTTGGTGGGAAATACAGATTTTATGTGAATCGGCGCTGGAAGACTCTGTTTCTTGGCGACTAGAAGATTT
TGGTTGTCGTGGTACAGCTAGCGAAAGTAAGGGTGATTCTTGCTTGGTTAAGGGTTATTTGCCGATATTTCAAGCACAGT
TATTAGATTTGGCGGCGCTGGGGTTATGGTTGCAGCAAGATGCCCTGTGTATAGGATTATCTTCTCCTACCTTGACTTGG
CAACTCATTGATGAGGAAGATTGGGCGAGTAGTTGGAAACAATATTGGCATCCGCAAGAAATAGGCGATCGCTTCCTCAT
CAATCCCGCATGGCTACCATCACCAGAAAACTACGATAGGTTAGTCATCCGCCTCGACCCCGGTGTAGCATTTGGTACAG
GAAACCATGCTACCACTCAATTATGTCTAGAATCTCTAGAAATGAGATTGAGTCAGGTTCCAAAATCATTTGTTAGTAAA
GATGCAGGTCAAGAACCTGTGATAATTGCGGATATTGGTTGTGGTTCTGGTATCCTTTCGATTGGGGCAATTCTATTAGG
CGCAGAGAAAGTCTATGCAGTAGATACCGACCCCTTAGCCGTGCAGTCAACCTTCAGCAATCGCGCCCTCAACGAGGTCA
ACCCAGAACGCCTCGTACCAGCAGAAGGTAGCGTAGATATCTTAAAGAAACTGATTGAACGCCCGGTAGATGGAATTGTC
TGCAATATTCTCGCTGATGTAATTATTCAATTAGTCCCAGAAATCAGCGAGATATCTAAACCTAGTACTTGGGCTATTTT
TAGCGGGATTTTAGTTGAACAATCTACTTCTGTTGTTGAGGCTTTAGAAAAACACGGTTGGGTAGTCGCTACTATGTGGA
AACGCAAAGAATGGTGCTGCTTAAATGTCAGGCGTACTTAA

Upstream 100 bases:

>100_bases
CGCGTACACAGTAACACTATAGGAGTCAGTAATCAGAACTCAGAAGTCAGCAGAAATAGTTTCTCCTGACTCCTGAATTC
TGGATTCTCAATTTTCAACA

Downstream 100 bases:

>100_bases
CTTATCAAGATTATGAATAGAGTGAGAGTGATGAGGTTCCGTCCACTATCGCTTTCTCTCATTTATAGCTGGGGACTGGG
GACTAGGTGAAAAGTCCTGT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MANTWWEIQILCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAALGLWLQQDALCIGLSSPTLTW
QLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENYDRLVIRLDPGVAFGTGNHATTQLCLESLEMRLSQVPKSFVSK
DAGQEPVIIADIGCGSGILSIGAILLGAEKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVVEALEKHGWVVATMWKRKEWCCLNVRRT

Sequences:

>Translated_306_residues
MANTWWEIQILCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAALGLWLQQDALCIGLSSPTLTW
QLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENYDRLVIRLDPGVAFGTGNHATTQLCLESLEMRLSQVPKSFVSK
DAGQEPVIIADIGCGSGILSIGAILLGAEKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVVEALEKHGWVVATMWKRKEWCCLNVRRT
>Mature_305_residues
ANTWWEIQILCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAALGLWLQQDALCIGLSSPTLTWQ
LIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENYDRLVIRLDPGVAFGTGNHATTQLCLESLEMRLSQVPKSFVSKD
AGQEPVIIADIGCGSGILSIGAILLGAEKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIVC
NILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVVEALEKHGWVVATMWKRKEWCCLNVRRT

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=226, Percent_Identity=34.9557522123894, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_ANAVT (Q3M6M1)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_324260.1
- ProteinModelPortal:   Q3M6M1
- SMR:   Q3M6M1
- STRING:   Q3M6M1
- GeneID:   3678964
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_3760
- NMPDR:   fig|240292.3.peg.3831
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   MSFGTGY
- PhylomeDB:   Q3M6M1
- ProtClustDB:   PRK00517
- BioCyc:   AVAR240292:AVA_3760-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33895; Mature: 33764

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTWWEIQILCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAAL
CCCCEEEHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
GLWLQQDALCIGLSSPTLTWQLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENYDR
HHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCE
LVIRLDPGVAFGTGNHATTQLCLESLEMRLSQVPKSFVSKDAGQEPVIIADIGCGSGILS
EEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHH
IGAILLGAEKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
HHHHHHCCCEEEEECCCCCEEEHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHH
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVVEALEKHGWVVATMWKRKEWCC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEECCCCEEE
LNVRRT
EEEECC
>Mature Secondary Structure 
ANTWWEIQILCESALEDSVSWRLEDFGCRGTASESKGDSCLVKGYLPIFQAQLLDLAAL
CCCEEEHHHHHHHHHHHHHHEEEHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
GLWLQQDALCIGLSSPTLTWQLIDEEDWASSWKQYWHPQEIGDRFLINPAWLPSPENYDR
HHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCE
LVIRLDPGVAFGTGNHATTQLCLESLEMRLSQVPKSFVSKDAGQEPVIIADIGCGSGILS
EEEEECCCEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEECCCCCCHHH
IGAILLGAEKVYAVDTDPLAVQSTFSNRALNEVNPERLVPAEGSVDILKKLIERPVDGIV
HHHHHHCCCEEEEECCCCCEEEHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHH
CNILADVIIQLVPEISEISKPSTWAIFSGILVEQSTSVVEALEKHGWVVATMWKRKEWCC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCEEEEEECCCCEEE
LNVRRT
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA